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	题名	作者	年代	出处	被引量
1	Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study显示文摘A highly sensitive, rapid and rugged liquid chromatography-tandem mass spectrometry(LC-ESI-MS/MS)method was developed for reliable estimation of amantadine(AMD), an antiviral drug in human plasma.The analyte and internal standard(IS), amantadine-d6(AMD-d6), were extracted from 200 m L plasma by solid phase extraction on Phenomenex Strata-X-C 33 m cartridges. Chromatography was performed on Synergi? Hydro-RP C18(150 mm ? 4.6 mm, 4 mm) analytical column using a mixture of acetonitrile and10 m M ammonium formate, p H 3.0(80:20, v/v) as the mobile phase. Detection and quantitation was done by multiple reaction monitoring in the positive ionization mode for AMD(m/z 152.1-135.1) and IS(m/z 158.0-141.1) on a triple quadrupole mass spectrometer. The assay was linear in the concentration range of 0.50–500 ng/m L with correlation coefficient(r2) Z 0.9969. The limit of detection of the method was 0.18 ng/m L. The intra-batch and inter-batch precisions were r 5.42% and the accuracy varied from98.47% to 105.72%. The extraction recovery of amantadine was precise and quantitative in the range of97.89%–100.28%. IS-normalized matrix factors for amantadine varied from 0.981 to 1.012. The stability of AMD in whole blood and plasma was evaluated under different conditions. The developed method was successfully applied for a bioequivalence study with 100 mg of AMD in 32 healthy volunteers. The reproducibility of the assay was determined by reanalysis of 134 subject samples.	Abhaysingh Bhadoriya Shivprakash Rathnam Bhavesh DasANDi Dharmesh Parmar Mallika Sanyal Pranav S.Shrivastav	2018	Journal of Pharmaceutical Analysis2018，8，3：	9
2	Differences in reactivity of pulverised coal in air (Oz/Nz) and oxy- fuel (Oz/CO2) conditions 显示文摘	Rathnam R K Elliott L K Wall T F Liu Y Moghtaderi B	2009	Fuel ProcessingTechnology2009，90，6：	1
3	Difference in reactivity of pulverized coal in (OJN~) and oxy-fuel(O~/CO2) conditions 显示文摘	Rathnam R K Elliott L K Wall T F	2009	Fuel Processing Technology2009，90，：	1
4	Differ-ences in reactivity of pulversied coal in air(O2/N2)and oxy-fuel(O2/CO2)conditions显示文摘	Rathnam R K Elliott L K Wall T F	2009	Fuel Process-ing Technology2009，90，6：	1
5	Molecular interaction study of binary mixtures of methyl benzoate : viscometric and ultrasonic study 显示文摘	RATHNAM M V SAYED R T BHANUSHALI K R	2012	J Mol Liq2012，166，1：	1
6	Differencesin reactivity of pulverised coal in air(O2/N2)and oxy-fuel(O2/CO2)conditions显示文摘	Rathnam R K Elliott L K Wall T F	2009	Fuel Processing Technology2009，90，6：	1
7	Nipple discharge: an early warning sign of breast cancer 显示文摘	Parthasarathy V Rathnam U	2012	Int J Prev Med2012，3，11：	1
8	Nipple discharge:an early warn-ing sign of breast cancer显示文摘	Parthasarathy V Rathnam U	2012	Int J Prev Med2012，3，：	1
9	Photosynthesis and photorespiratory carbon metabolism in mesophyll protoplasts and chloroplasts isolated from isogenic and tetraploid cultivars of ryegrass (Lolium perene L) 显示文摘	Rathnam C K Cholett R	1980	Plant Physiol1980，65，：	1
10	Differences in reactivity of pulverised coal in air (O2/N2 ) and oxyfuel (O2/CO2) conditions 显示文摘	R K Rathnam L K Elliott T F Wall	2009	Fuel Processing Technology2009，90，6：	1
11	Nipple discharge:an early warning sign of breast cancer显示文摘	Parthasarathy V Rathnam U		0，，：	1
12	An overview on oxyfuel coal combustion--State of the art research and technology development 显示文摘	WALL T LIU Y H SPERO C ELLIOTT L KHARE S RATHNAM R ZEENATHAL F MOGHTADERI B BUHRE B SHENG Chang-dong GUPTA R YAMADA T MAKINO K YU J L	2009	Chemical Engineering Research and Design2009，87，10：	1
13	Carbopol-based gels for nasal delivery of progesterone显示文摘	Rathnam G Naraymlml N Ilavarasan R	2008	AAPS PharmSciTech2008，9，4：	1
14	Palmistry: A tool for dental caries prediction显示文摘	Madan N Rathnam A Bajaj N	2011	Indian J Dent Res2011，22，2：	1
15	An overview on oxyfuel coal combustion-state of the art research and technology development显示文摘	Wall T F Liu Y H Spero C Elliott L Khare S Rathnam R Zeenathal F Moghtaderi B Sheng C D Gupta R Yamada T Makino K Yu J L		0，，08：	1
16	An overview on oxyfuel coal combustion—State of the art research and technology development显示文摘	Terry Wall Yinghui Liu Chris Spero Liza Elliott Sameer Khare Renu Rathnam Farida Zeenathal Behdad Moghtaderi Bart Buhre Changdong Sheng Raj Gupta Toshihiko Yamada Keiji Makino Jianglong Yu	2009	Chemical Engineering Research and Design2009，，8：	1
17	Differences in Reactivity of Pulverised Coal in Air (O2/N2) and Oxy- fuel (O2/CO2) Conditions 显示文摘	Rathnam R K Elliott L K Wall T F	2009	Fuel Processing Technol- ogy2009，90，6：	1
18	An overview on oxy-fuel coal combustion--state of the art research and technology development 显示文摘	Wall T Liu Y Spero C Elliott L Khare S Rathnam R Zeenathal F Moghtaderi B Buhre B Sheng C	2009	Chemical Engineering Research and Design2009，87，8：	1
19	Differences in reactivity of pulverised coal in air (O 2 /N 2 ) and oxy-fuel (O 2 /CO 2 ) conditions显示文摘	Renu Kumar Rathnam Liza K. Elliott Terry F. Wall Yinghui Liu Behdad Moghtaderi	2009	Fuel Processing Technology2009，，6：	1
20	Differences in reactivity of pulverised coal in air (O 2 /N 2 ) and oxy-fuel (O 2 /CO 2 ) conditions显示文摘	Renu Kumar Rathnam Liza K. Elliott Terry F. Wall Yinghui Liu Behdad Moghtaderi	2009	Fuel Processing Technology2009，，6：	1

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