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| 1 | Engineered trimeric ACE2 binds viral spike protein and locks it in'Thfee-up'conformation to potently inhibit SARS-CoV-2 infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in a severe global pandemic Following SARS-CoV,SARS-CoV-2 is yet another emerge nt beta-coronavirus threate ning human health.1 However,seventeen years after the SARS pandemic,no targeted vaccines or therapeutics have been approved for SARS,while some of them might have held promise for treating COVID-19.Many neutralizing antibodies against SARS-CoV-2 are currently being developed.However,RNA viruses are known to have high mutation rates. | Liang Guo Wenwen Bi Xinling Wang Wei Xu Renhong Yan Yuanyuan Zhang Kai Zhao Yaning Li Mingfeng Zhang Xia Cai Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Bobo Dang | 2021 | Cell Research2021，31，1： | 5 |
| 2 | Flexoelectric materials and their related applications: A focused review显示文摘Flexoelectricity refers to the mechanical-electro coupling between strain gradient and electric polarization, and conversely, the electro-mechanical coupling between electric field gradient and mechanical stress. This unique effect shows a promising size effect which is usually large as the material dimension is shrunk down. Moreover, it could break the limitation of centrosymmetry, and has been found in numerous kinds of materials which cover insulators, liquid crystals, biological materials, and semiconductors. In this review, we will give a brief report about the recent discoveries in flexoelectricity, focusing on the flexoelectric materials and their applications. The theoretical developments in this field are also addressed. In the end, the perspective of flexoelectricity and some open questions which still remain unsolved are commented upon. | Longlong SHU Renhong LIANG Zhenggang RAO Linfeng FEI Shanming KE Yu WANG | 2019 | Journal of Advanced Ceramics2019，8，2： | 4 |
| 3 | Electric modulation of conduction in MAPbBr_(3) single crystals显示文摘The resistive switching(RS)mechanism of hybrid organic–inorganic perovskites has not been clearly understood until now.A switchable diode-like RS behavior in MAPbBr3 single crystals using Au(or Pt)symmetric electrodes is reported.Both the high resistance state(HRS)and low resistance state(LRS)are electrode-area dependent and light responsive.We propose an electric-fielddriven inner p–n junction accompanied by a trap-controlled space-charge-limited conduction(SCLC)conduction mechanism to explain this switchable diode-like RS behavior in MAPbBr_(3) single crystals. | Shanming Ke Shangyu Luo Jinhui Gong Liwen Qiu Renhong Liang Yangbo Zhou Bingcheng Luo Baochang Cheng Li Wang Longlong Shu | 2021 | Journal of Advanced Ceramics2021，10，2： | 0 |
| 4 | ACE2-targeting monoclonal antibody as potent and broad-spectrum coronavirus blocker显示文摘The evolution of coronaviruses,such as SARS-CoV-2,makes broad-spectrum coronavirus preventional or therapeutical strategies highly sought after.Here we report a human angiotensin-converting enzyme 2(ACE2)-targeting monoclonal antibody,3E8,blocked the S1-subunits and pseudo-typed virus constructs from multiple coronaviruses including SARS-CoV-2,SARS-CoV-2 mutant variants(SARS-CoV-2-D614G,B.1.1.7,B.1.351,B.1.617.1,and P.1). | Yuning Chen Ya-Nan Zhang Renhong Yan Guifeng Wang Yuanyuan Zhang Zhe-Rui Zhang Yaning Li Jianxia Ou Wendi Chu Zhijuan Liang Yongmei Wang Yi-Li Chen Ganjun Chen Qi Wang Qiang Zhou Bo Zhang Chunhe Wang | 2021 | Signal Transduction and Targeted Therapy2021，6，9： | 0 |
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