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| 1 | Highly efficient derivation of ventricular cardiomyocytes from induced pluripotent stem cells with a distinct epigenetic signature显示文摘从 pluripotent 干细胞导出的 Cardiomyocytes 能在药测试,疾病建模和基于房间的治疗被使用。没有 procardiogenic 生长因素,然而,从 pluripotent 干细胞的 cardiomyogenesis 的效率通常是低的,产生 cardiomyocyte 人口是异构的。这里,我们证明导致的 pluripotent 干细胞( iPSCs )能从鼠科的室的 myocytes ( VM )被导出,并且与从各种各样的体的房间类型导出的 iPSCs 的另外的报告一致,自发地作为与遗传上匹配的胚胎的干细胞(转换字符)或 iPSCs 相比区分 cardiomyocytes 进跳动的显著地更高的倾向从尾巴尖端成纤维细胞导出的 导出VM 的 iPSCs ( ViPSCs )展览。惊人地,导出 ViPSC 的 cardiomyocytes 显示的多数室的显型。在 ViPSCs 的提高的室的 myogenesis 在区别的早阶段经由心血管的祖先的增加的数字被调停。以便从 ViPSCs 调查提高的室的 myogenesis 的机制,我们执行了全球基因表示和 DNA methylation 分析,它揭示了可以涉及在 pluripotent 干细胞指定 VM 命运的不同 epigenetic 签名。 | Huansheng Xu B Alexander Yi Hao Wu Christoph Bock Hongcang Gu Kathy O Lui Joo-Hye C Park Ying Shao Alyssa K Riley Ibrahim J Domian Erding Hu Robert Willette John Lepore Alexander Meissner Zhong Wang Kenneth R Chien | 2012 | Cell Research2012，22，1： | 7 |
| 2 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 6 |
| 3 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | The Lancet2011，，9785： | 2 |
| 4 | National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants显示文摘 | Goodarz Danaei Mariel M Finucane Yuan Lu Gitanjali M Singh Melanie J Cowan Christopher J Paciorek John K Lin Farshad Farzadfar Young-Ho Khang Gretchen A Stevens Mayuree Rao Mohammed K Ali Leanne M Riley Carolyn A Robinson Majid Ezzati | 2011 | 2011 (9785)2011，，9785： | 2 |
| 5 | A here dimensional osteochondral composite scaffold for articular cartilage repair显示文摘 | SHERWOOD J K RILEY S L PALAZZOLO R | 2002 | Biomaterials2002，23，： | 1 |
| 6 | Distraction osteogenesis in adult obstructive sleep apnea surgery:a preliminary report显示文摘 | Li K K Powell N B Riley R W | 2002 | J Oral Maxillofac Surg2002，60，1： | 1 |
| 7 | Radiationinduced ocular motor cranial nerve palsies in patients with pituitary tumor显示文摘 | Vaphiades MS Spencer SA Riley K | 2011 | J Neurophthalmol2011，31，3： | 1 |
| 8 | Molecular characterization and phylogenetic arialysis of Murray Valley encephalitis virus and West Nile virus(Kunjin subtype) from an arbovirus disease outbreak in horses in Victoria, Australia, in 2011显示文摘 | Mann RA Fegan M O' Riley K | 2013 | Journal of Veterinary Diagnostic Investigation2013，25，1： | 1 |
| 9 | Innate immune respons to malar-ia:rapid induction of IFN-gamma from human NK cells by live Plasmo-dium falciparum-infected erythrocytes显示文摘 | Artavanis-Tsakonas K Riley EM | | 0，，06： | 1 |
| 10 | In vitro digestibility of raw starches extracted from five Yam species grown in Jamaica显示文摘 | | 2004 | Starch/St(a)rke2004，56，： | 1 |
| 11 | In vitro activity of Melaleuca alternifolia (tea tree) oil against dermatophytes and other filamentous fungi 显示文摘 | HAMMER K A CARSON C F RILEY T V | 2002 | Journal Antimicrobial Chemotherapy2002，50，2： | 1 |
| 12 | Treatment-related deaths during induction and first remission of acute myeloid leukemia in children treated on tenth medical research council acute myeloid leukemia trial (MRC AML 10) the MCR childhood leukemia working party显示文摘 | Hamn IM Wheatrey K | 1999 | Br J Haematol1999，106，2： | 1 |
| 13 | Petroleum generation by laboratoryscale pyrolysis over six years simulating conditions in a subsiding basin显示文摘 | Saxby J D Riley K W | 1984 | Nature1984，308，8： | 1 |
| 14 | Urokinase plasminogen activator receptor expression and associated functions in ovarian carcinoma 显示文摘 | Ahmed N Riley C Oliva K | 2005 | British Journal of Cancer2005，92，： | 1 |
| 15 | Improved survival of vitrified porcine embryos after partial delipation through chemically stimulated li-polysis and inhibition of apoptosis显示文摘 | Men H Agca Y Riley L K | 2006 | Theriogenology2006，66，： | 1 |
| 16 | Fiber-type susceptibility to eccentric contraction-induced damage of hindlimb-unloaded rat AL muscles 显示文摘 | Vijayan K Thompson J L Norenberg K M Fitts R H Riley D A | 2001 | J Appl Physiol2001，90，3： | 1 |
| 17 | The pivotal role of hepatocytes in drug discovery显示文摘 | Soars MG McGinnity DF Grime K Riley RJ | 2007 | Chem Biol Interact2007，，： | 1 |
| 18 | Detecting Food and Waterborne Viruses by Surface - Enhanced Raman Spectroscopy显示文摘 | Cui Fan Zhiqiang I-Iu Lela K Riley | 2010 | Journal of Food Science2010，75，5： | 1 |
| 19 | Ligamentous anatomy of the distal clavicle显示文摘 | Renfree K J Riley MK Wheeler D | 2003 | J Shoulder Elbow Surg2003，12，： | 1 |
| 20 | Dynamic stability inelders: momentum control in locomotor ADL 显示文摘 | KAYA B K KREBS D E RILEY P O | 1998 | J GerontolA Biol Sci Med Sci1998，53，2： | 1 |
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