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| 1 | Technical and conceptual considerations forusing animated stimuli in studies of animalbehavior显示文摘Rapid technical advances in the field of computeropened new avenues in animal behavior research.animation (CA) and virtual reality (VR) haveAnimated stimuli are powerful tools as theyoffer standardization, repeatability, and complete control over the stimulus presented, thereby"reducing" and "replacing" the animals used, and "refining" the experimental design in line withthe 3Rs. However, appropriate use of these technologies raises conceptual and technical questions.In this review, we offer guidelines for common technical and conceptual considerations related tothe use of animated stimuli in animal behavior research. Following the steps required to create ananimated stimulus, we discuss (I) the creation, (11) the presentation, and (111) the validation of CAsand VRs. Although our review is geared toward computer-graphically designed stimuli, consider-ations on presentation and validation also apply to video playbacks. CA and VR allow both new be-havioral questions to be addressed and existing questions to be addressed in new ways, thus weexpect a rich future for these methods in both ultimate and proximate studies of animal behavior. | Laura CHOUINARD-THULY Stefanie GIERSZEWSKI Gil G. ROSENTHAL Simon M. READER Guillaume RIEUCAU Kevin L. Woo Robert GERLAI Cynthia TEDORE Spencer J. INGLEY John R. STOWERS Joachim G.FROMMENI Francine L. DOLINS Klaudia WITTE | 2017 | Current Zoology2017，63，1： | 10 |
| 2 | Importance of bifurcation angle in bifurcation stenting显示文摘Bifurcation coronary lesions are relatively frequent in today's interventional cardiology practice,averaging between 10%-15% of all percutaneous coronary interventions(PCIs).1 Several problems inherent in the treatment of bifurcation lesions are periprocedural side branch(SB)compromise(composite of SB closure or appearance of significant ostial stenosis after main vessel(MV)stenting causing ischemia)frequently related to periprocedural myonecrosis,relatively higher restenosis rates especially in two-stent techniques,and higher rates of stent thrombosis in different time frames.1-4 The lead author and other investigators demonstrated that both periprocedural result and long-term results could be influenced by bifurcation angulations.The purpose of this study is to show why and how bifurcation angulations are important for bifurcation stenting. | Dobrin Vassilev Alexander Alexandrov Dan Le Katrina Nguyen James Nguyen Hung Phan Robert J. Gil | 2012 | Chinese Medical Journal2012，，22： | 7 |
| 3 | QT hysteresis in long-QT syndrome children with exercise testing显示文摘背景先天的长 QT 症候群(LQTS ) 是导致能引起与延长改正率的 QT 间隔和多态的室的心悸亢进联系的中略和突然的死亡的反常心脏的极化的继承离子隧道混乱。在成年人的几研究证明 LQTS 病人与哪个的正常题目相比改变了 QT 改编到心率变化在 QT 圆长度阴谋形成“一个磁滞现象环”。这研究是观察在长在孩子测试的锻练期间改变 QT 症候群(LQTS ) 病人的 QT 间隔,探索这些题目根据 1993 个 LQTS 诊断标准被划分成 3 个组的 LQTS.Methods 的新诊断方法。组 1:得分了的 LQTS 组(n=17 ) 或 4 削尖显示明确的 LQTS 的 = 。组 2:中间的组(n=16 ) ,延长了 QT 间隔,但是获得了 1.5 ~ 3.5 的病人。组 3:正常控制组(n=18 ) 。所有学习人口的平均年龄是(12.3 ??????( | GAO Dong-sheng FANG Wei-yi Christine Chiu-Man Joel Kirsh Gil Gross Robert M. Hamilton | 2007 | Chinese Medical Journal2007，，3： | 2 |
| 4 | Risk of Upper Gastrointestinal Injury and Events in Patients Treated With Cyclooxygenase (COX)-1/COX-2 Nonsteroidal Antiinflammatory Drugs (NSAIDs), COX-2 Selective NSAIDs, and Gastroprotective Cotherapy: An Appraisal of the Literature显示文摘 | Robert W. Dubois Gil Y. Melmed James M. Henning Myriam Bernal | 2004 | JCR: Journal of Clinical Rheumatology2004，，4： | 1 |
| 5 | Local Delivery Versus Intracoronary Infusion of Abciximab in Patients With Acute Coronary Syndromes显示文摘 | Francesco Prati Davide Capodanno Tomasz Pawlowski Vito Ramazzotti Mario Albertucci Alessio La Manna Marilena Di Salvo Robert J. Gil Corrado Tamburino | 2010 | JACC: Cardiovascular Interventions2010，，9： | 1 |
| 6 | A genome-wide association study of aging显示文摘 | Stefan Walter Gil Atzmon Ellen W. Demerath Melissa E. Garcia Robert C. Kaplan Meena Kumari Kathryn L. Lunetta Yuri Milaneschi Toshiko Tanaka Gregory J. Tranah Uwe V?lker Lei Yu Alice Arnold Emelia J. Benjamin Reiner Biffar Aron S. Buchman Eric Boerwinkle | 2011 | Neurobiology of Aging2011，，11： | 1 |
| 7 | Changes in coronary bifurcations after stent placement in the main vessel and balloon opening of stent cells:theory and practical verification on a bench-test model显示文摘Objective To describe changes that occur in stent morphology and structure after its implantation in coronary bifurcation.Side branch (SB) compromise after stenting of main vessel in coronary bifurcation is a major intraprocedural problem and for the long term,as a place of restenosis.Methods We created an elastic wall model (parent vessel diameter 3.5mm,daughter branches 3.5mm and 2.75mm)with 30,45 and 60 degree distal angulation between branches.After stent implantation,struts to the side branch were opened with 2.0mm and consequently 3.0mm diameter balloons.Subsequent balloon redilatations and kissing balloon inflations (KBI) were performed.All stages of the procedure were photographed with magnification up to 100 times.Results We found that the leading mechanism for side branch compromise was carina displacement,and discovered theoretical description for expected ostial stenosis severity.Based on our model we found that displacement of bifurcation flow divider cause SB stenosis with almost perfect coincidence with our theoretical predictions.Opening of stent cells through the proximal and distal stent struts always increased interslrut distance,but never achieved good apposition to the wall.Balloon diameter increase didn't give proportional enlargement in stent cell diameters.KBI leads to some small better stent positioning,correcting main vessel strut dislodgment from wall,but never gave full strut-wall contact.Distance between struts and wall was minimal only when the stent cell perfectly faced ostium of SB.This was also our observation that the shape of ostium of SB becomed eUiptically-bean shaped after stent implantation and generally kept that shape during consequent stages of experiment.Measured diameter and area stenosis were perfectly fitted and theoretically predicted from our concept Conclusion We have described stent-wall deformations in stent-balloon technique for treatment of coronary bifurcation demonstrating carina displacement as possibly main mechanism of side branch compromise after main vessel stenting.We have shown that KBI could not give full strut-wall contact if there is no perfect facing of stem cell and SB ostium.(J Geroatr Cardool 2008;5(1):43-49) | Dobrin Vassilev Robert Gil | 2008 | Journal of Geriatric Cardiology2008，5，1： | 1 |
| 8 | Misdiagnosed Aortic Intramural Hematoma and the Role of Intravascular Ultrasound Imaging in Detection of Acute Aortic Syndrome:A Case Report显示文摘Acute aortic syndrome includes classic aortic dissection,aortic intramural hematoma,and penetrating atherosclerotic ulcer– a group of conditions that are defined by their dynamic evolution and similar clinical manifestation.Accurate diagnosis and prompt treatment are essential as all the aforementioned conditions are a signifi cant threat to a patient’s life.However,acute aortic syndrome and especially aortic intramural hematoma may be challenging diagnostic problems.Intravascular ultrasound imaging is a diagnostic method that can be useful for more thorough evaluation of the aortic lesion and can particularly aid in discerning the different forms of acute aortic syndrome.We present a case of a patient with aortic intramural hematoma that was missed by conventional imaging studies but was successfully visualized with intravascular ultrasound imaging. | Niya Mileva Dobrin Vassilev Robert Gil Gianluca Rigatelli | 2018 | Cardiovascular Innovations and Applications2018，，B01： | 1 |
| 9 | The role of cationic anirimicrobial peptides in innate host defences显示文摘 | Robert EW Hancock Gil D | 2000 | Trends in Microbiology2000，8，： | 1 |
| 10 | Acute Pancreatitis—Progress and Challenges: A Report on an International Symposium显示文摘 | Elham Afghani Stephen J. Pandol Tooru Shimosegawa Robert Sutton Bechien U. Wu Santhi Swaroop Vege Fred Gorelick Morihisa Hirota John Windsor Simon K. Lo Martin L. Freeman Markus M. Lerch Yoshihisa Tsuji Gil Y. Melmed Wahid Wassef Julia Mayerle | 2015 | Pancreas2015，，8： | 1 |
| 11 | Entrapment of a volatile lipophilic aroma compound ( d -limonene) in spray dried water-washed oil bodies naturally derived from sunflower seeds ( Helianthus annus )显示文摘 | Ian D. Fisk Robert Linforth Gil Trophardy David Gray | 2013 | Food Research International2013，，1： | 1 |
| 12 | Theoretical prediction of side branch compromise after main branch stenting in coronary bifurcation显示文摘One of the main problems of treatment of bifurcation lesions is side branch (SB) stenosis appearing after stent placement in the main vessel. The aim of this study was to create quantitative method for prediction of side branch compromise extent. We accepted that the main mechanism for SB ostial stenosis is flow divider (FD) displacement from stent struts after stent implantation in the main vessel. Using easily measurable parameters from coronary angiography, as SB diameter, angle á (initial angle between axes of parent vessel and SB axis) and angle á' (angle between above mentioned axes after stent placement) we can calculate percentage diameter stenosis at branch ostium (%DS): %DS = sin (á - á')/(tan á). In boundary condition of full FD displacement %DS = cos á. We tested our theoretical predictions with fluoroscopic observation of elastic wall model of bifurcation (45o distal angle between branches) permitting wall deformations with stent. There is full coincidence of values of %DS and percentage area stenosis (%AS). The regular formulas for calculations of %DS and %AS overestimate stenosis severity between 10% and 25%. Our model tests have shown full coincidence between predicted values for %DS and observed values. We demonstrate that part of the SB ostium is not visible in regular angiography and contributes to ostial lumen area. This is a method that permits quantitative prediction of side branch compromise. | Dobrin Vassilev Robert Gil | 2008 | Journal of Geriatric Cardiology2008，5，2： | 0 |
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