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| 1 | Knockdown of ecdysis-triggering hormone gene with a binary UAS/GAL4 RNA interference system leads to lethal ecdysis deficiency in silkworm显示文摘被触发蜕皮的荷尔蒙(ETH ) 是在大多数昆虫的蜕皮过程的一个集成因素,包括 Bombyx 粗腐殖质 i (蚕) 。在蚕理解 ETH 基因的函数,我们开发了一条有效途径到击倒在 vivo 的 ETH 的表达式成功地在另外的昆虫种类基于 RNA 干扰(RNAi ) 和是的一个二进制 UAS/GAL4 表达式系统使用了。二种转基因的蚕与这个方法被建立:有在 UAS 的控制下面的 ETH RNAi 顺序的受动器紧张和有编码的 GAL4 的使活跃之物紧张在 Bombyx 粗腐殖质 i 的控制下面定序细胞质的 actin3。由穿过二紧张,双 positive 转基因的蚕被获得,并且他们的 ETH 表示被发现比每个单身的积极转基因的父母的戏剧性地低。证明致命到双 positive 的严重蜕皮缺乏在 pharate 秒中间形态幼虫的阶段的转基因的蚕,当单个积极的转基因或野类型的蚕有正常蜕皮时。这条 UAS/GAL4 RNAi 途径提供一个方法在不同发展阶段学习内长的蚕基因的功能。 | Hongjiu Dai Li Ma Jue Wang Rongjing Jiang Zhugang Wang Jian Fei | 2008 | Acta Biochimica et Biophysica Sinica2008，40，9： | 12 |
| 2 | Geometry,kinematics and evolution of the Tongbai orogenic belt显示文摘The Tongbai orogenic belt (TOB) is composed of six tectonic units. From south to north these units are: Tongbai gneiss rise (TGR); Hongyihe-Luozhuang eclogite belt (HLE); Ma- opo-Hujiazhai igneous rock belt (MHI); Zhoujiawan flysch belt (ZFB); Yangzhuang greenschist belt (YGB); and Dongjiazhuang marble belt (DMB).The geometry and kinematic images of the TOB in- clude: the antiformal structures caused by a later uplift process, the top-to-north ductile shear struc- ture that related to a process that the ultrahigh pressure rocks are brought to surface, the top-to-south ductile shear thrust and the sinistrial shear structures related to a south-north direction compression, and the east-west direction fold structures in the upper crust. In the view of the multistage subduc- tion-collision orogenic belt, according to the characters of petrology and its distribution, geometry, kinematics and structural chronology in these tectonic units, tectonic evolution of the TOB can be divided into four stages: oceanic crust subduction during 400―300 Ma, continental collision during 270―250 Ma, continental deep subduction and uplift during 250―205 Ma and doming deformation during 200―185 Ma. | HUANG Shaoying XU Bei WANG Changqiu ZHAN Sheng DENG Rongjing | 2006 | Science China Earth Sciences2006，49，8： | 9 |
| 3 | The Effect of Home-Based Cardiac Rehabilitation on Functional Capacity,Behavior,and Risk Factors in Patients with Acute Coronary Syndrome in China显示文摘Aim:To investigate the effect of home-based cardiac rehabilitation on functional capacity,health behavior,and risk factors in patients with acute coronary syndrome in China.Methods:Eighty patients with acute coronary syndrome were enrolled in this prospective randomized controlled study.Patients in the cardiac rehabilitation group(n=52)received home-based cardiac rehabilitation with a heart manual and a home exercise video for 3 months and patients in the control group(n=28)received only routine secondary prevention.The 6-min walk distance,laboratory test results,healthy behavior(questionnaire),quality of life(12-item Short Form Health Survey),anxiety(7-item Generalized Anxiety Disorder Questionnaire),and depression(9-item Patient Health Questionnaire)were evaluated at the beginning and after treatment for 3 months.Results:Compared with baseline data,52 patients who participated in cardiac rehabilitation had longer 6-min walk distance(515.26±113.74 m vs 0.445.30±97.92 m,P<0.0002),higher proportions of“always exercise”(78.26% vs.28%,P<0.05),“always limit food with sugar”(65.22% vs 12%,P<0.05),“always eat fruits 200–400 g every day”(82.61% vs.4%,P<0.05).and“always eat vegetables 300–500 g every day”(21.74%vs.12%,P<0.06)after treatment for 3 months.The low-density lipoprotein cholesterol control rate(52.17% vs.28%,P<0.05)and the systolic blood pressure control rate(100%vs.68%,P<0.05)were also signifi cantly increased after treatment for 3 months in the cardiac rehabilitation group.No signifi cant increase was found in the control group after treatment for 3 months.No cardiac-event related to home exercise was reported in both groups.Conclusion:Home-based cardiac rehabilitation is a feasible and available cardiac rehabilitation mode in China. | Rongjing Ding Jianchao Li Limin Gao Liang Zhu Wenli Xie Xiaorong Wang Qin Tang Huili Wang Dayi Hu | 2017 | Cardiovascular Innovations and Applications2017，，B02： | 5 |
| 4 | Efficient and stable genera-tion of transgenic silkworm, Bombyx mori with the lepi-dopteran derived transposon piggyBac显示文摘The piggyBac transposable element was suc-cessfully used for generation of the transgenic silkworm, Bombyx mori. The EGFP was adopted in this study as a screening marker in transgenic vector under the control of an artificial promoter containing Pax-6 binding sites that can drive eye-specific genes expression in various insect species including B. mori and Drosophila. 111 independent trans-genic lines were obtained among 700 fertile G0 moths. Most of the transgenic lines contained two or more chromosomal insertions of the EGFP marker, which were stably inherited over more than six generations during the time of this pro-ject. PiggyBac-mediated transposition was confirmed by identifying the characteristic TTAA duplication sequence at the insertion sites. The stable and high efficient transmission of a genetic marker into B. mori confirms the usage of this vector-marker system for industrial production and theo-retical research. | DAI Hongjiu XU Guojiang Thomas Jean-luc WANG Zhugang JIANG Rongjing FEI Jian | 2005 | Chinese Science Bulletin2005，50，15： | 2 |
| 5 | Animal exercise studies in cardiovascular research:Current knowledge and optimal design--A position paper of the Committee on Cardiac Rehabilitation,Chinese Medical Doctors’Association显示文摘Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against cardiovascular diseases However,the underlying mechanisms of the beneficial effects of exercise have yet to be elucidated.Animal exercise studies are widely used to investigate the key mechanisms of exercise-induced cardiovascular protection.However,standardized procedures and well-established evaluation indicators for animal exercise models are needed to guide researchers in carrying out effective,high-quality animal studies using exercise to prevent and treat cardiovascular diseases.In our review,we present the commonly used animal exercise models in cardiovascular research and propose a set of standard procedures for exercise training,emphasizing the appropriate measurements and analysis in these chronic exercise models.We also provide recommendations for optimal design of animal exercise studies in cardiovascular research,including the choice of exercise models,control of exercise protocols,exercise at different stages of disease,and other considerations,such as age,sex,and genetic background.We hope that this position paper will promote basic research on exercise-induced cardiovascular protection and pave the way for successful translation of exercise studies from bench to bedside in the prevention and treatment of cardiovascular diseases. | Yihua Bei Lei Wang Rongjing Ding Lin Che Zhiqing Fan Wei Gao Qi Liang Shenghui Lin Suixin Liu Xiao Lu Yuqin Shen Guifu Wu Jian Yang Guolin Zhang Wei Zhao Lan Guo Junjie Xiao | 2021 | Journal of Sport and Health Science2021，10，6： | 2 |
| 6 | FEM-based strain analysis study for multilayer sheet forming process显示文摘纤维金属把压成薄片比有许多优点传统把压成薄片(例如,没有合成织物表的失败的风险,纤维的任何类型和树脂材料能被放在任何地方在金属性的层之间) 。而且,严格地控制在纤维金属的力量把压成薄片的温度和穿孔机的进程要求也是不比那些在紧的传统把压成薄片。为了推进,探索新奇方法,这研究进行一个有限元素基于方法(女性底) 由使用 3A 方法的多层的空白上的紧张分析。象起皱和骨折那样的不同形成模式被使用试验性、数字的研究讨论。Hydroforming 被用于多层的形成。Barlat 2000 收益标准和 DYNAFORM/LS-DYNA 被用于模拟。最佳的进程参数根据固定死文件夹差距和可变的洞压力被决定。这研究的结果将在使用 3A 方法形成的多层的结构的力学上提高知识并且扩展它的商业应用。 | Rongjing ZHANG Lihui LANG Rizwan ZAFAR | 2015 | Frontiers of Mechanical Engineering2015，10，4： | 2 |
| 7 | Research on One-Piece Structure Target Flow Sensing Technology Based on Fiber Bragg Grating显示文摘鉴于在传统的水力的系统的察觉存在的问题,例如大量传感器和低测量精确性,一个新一个片目标类型流动传感器基于纤维布拉格栅栏(FBG ) 被设计并且研究。紧缩的结构被设计,它是方便的基于 FBG 的原则和目标类型流动传感器的结构的分析被拆除,处理,并且安装。在液体流动放的目标的力量被变成 FBG 波长飘移,一种相应关系地。温度和种类的生气敏感上的问题被使用相称性地在伸臂的两表面上粘贴的两倍 FBG 有效地解决。液体状态上的影响在软件通过模拟被分析流畅,并且结果证明影响比传统的结构的小。在水力的系统的实验的结果证明在在双 FBG 中央波长的变化之间有一种好线性关系,在目标表上装载的质量有一种好线性关系,并且敏感是两次单个 FBG 敏感的。 | Chuntong LIU Zhengyi ZHANG Hongcai LI Zhenxin HE Xiaofeng ZHAO Rongjing WU | 2016 | Photonic Sensors2016，6，4： | 2 |
| 8 | Sensing cytochrome P4501A1 activity by a resorufin-based isoform-specific fluorescent probe显示文摘Cytochrome P4501 A1(CYP1A1),a heme-containing monooxygenase,is of particular importance for human health because of its vital roles in the metabolic activation of pro-carcinogenic compounds to the carcinogens.Deciphering the relevance of CYP1A1 to human diseases and screening of CYP1A1 modulators require reliable tool(s)for probing this key enzyme in complex biological matrices.Herein,a practical and ultrasensitive fluorescence-based assay for real-time sensing CYP1A1 activities in biological systems has been developed,via designing an isoform-specific fluorogenic sensor for CYP1A1(CHPO).The newly developed fluorogenic substrate for CYP1A1 has been carefully investigated in terms of specificity,sensitivity,precision,quantitative linear range and the anti-interference ability.The excellent selectivity,strong anti-interference ability and fast response kinetics,making the practicability of CHPObased CYP1A1 activity assay is better than that of most reported CYP1A1 activity assays.Furthermore,CHPO has been successfully used for imaging CYP1A1 activities in living cells and human tissues,as well as for high-throughput screening of CYP1A1 inhibitors using tissue preparations as enzyme sources.Collectively,this study provided a practical fluorogenic sensor for real-time sensing CYP1A1 in complex biological systems,which would strongly facilitate the investigations on the relevance of CYP1A1 to human diseases and promote high-throughput screening of CYP1A1 modulators for biomedical applications. | Qiang Jin Hongying Ma Lei Feng Ping Wang Rongjing He Jing Ning Ling Yang Guangbo Ge | 2020 | Chinese Chemical Letters2020，31，11： | 2 |
| 9 | Research hotspots and trends of cardiopulmonary exercise test:Visualization analysis based on citespace显示文摘The study aims to grasp the hot spots and trends of global cardiopulmonary exercise research.Web of Science(WoS)core collection and Derwent Innovation Index database were retrieved to collect literature from 2002 to 2022 with Cardiopulmonary Exercise Test(CPET)as the retrieval theme.CiteSpace was used to conduct bibliometrics and visual analysis of 6679 pieces of literature in the web of science core collection database and 251 patent data in the Derwent Innovation Index database.The results show that:(1)the number of CPET theme research papers is increasing year by year,and the main research fields are cardiology,respiratory system,sports science,etc.;(2)The main research hot spots of CPET include exercise prescription,exercise and heart failure,COVID-19 cardiopulmonary rehabilitation and evaluation,etc.;(3)The development trend of CPET technology is majorly in the direction of intelligence,portability,individualization and the integration of Virtual Reality(VR)technology and evidence-based research of CPET guiding clinical decision-making. | Yu Zhao Jianchao Li Chunjing Tao Rongjing Ding | 2022 | Medicine in Novel Technology and Devices2022，，4： | 1 |
| 10 | Rho A/ROK pathway related to the mechanism of higher susceptibility to spasm in RA than in IMA显示文摘 | Kun X Lefeng W Rongjing D | 2009 | J Card Surg2009，24，6： | 1 |
| 11 | Receptor and ligand based 3D-QSAR study for a series of non-nucleoside HIV-1 reverse transcriptase inhibitors 显示文摘 | Rongjing Hu Florent Barbault Michel Delamar | 2009 | Bioorganie & Medicinal Chemistry2009，17，6： | 1 |
| 12 | QSAR models for 2-amino-6-arylsufonylbenzonitriles and congeners HIV-1 reverse transcriprase inhibitors based on linear and nonlinear regression methods显示文摘 | Rongjing Hu Jean Pierre Doucet Michel Delamar | 2009 | European lournal of Medicinal Chemistry2009，44，5： | 1 |
| 13 | The synthesis and characterization of polyurethane/clay nanocomposites显示文摘 | Zhang Xinmin Xu Rongjing Wu Zenggang | 2003 | Polymer International2003，52，： | 1 |
| 14 | Effect of raceway geometry parameters on the carrying capability and the service life of a four-point-contact slewing bearing显示文摘 | Xuehai Gao Xiaodiao Huang Hua Wang Rongjing Hong Jie Chen | 2010 | Journal of Mechanical Science and Technology2010，，10： | 1 |
| 15 | Weighted Particle Swarm Clustering Algorithm for Self-Organizing Maps显示文摘The traditional K-means clustering algorithm is difficult to determine the cluster number,which is sensitive to the initialization of the clustering center and easy to fall into local optimum.This paper proposes a clustering algorithm based on self-organizing mapping network and weight particle swarm optimization SOM&WPSO(Self-Organization Map and Weight Particle Swarm Optimization).Firstly,the algorithm takes the competitive learning mechanism of a self-organizing mapping network to divide the data samples into coarse clusters and obtain the clustering center.Then,the obtained clustering center is used as the initialization parameter of the weight particle swarm optimization algorithm.The particle position of the WPSO algorithm is determined by the traditional clustering center is improved to the sample weight,and the cluster center is the“food”of the particle group.Each particle moves toward the nearest cluster center.Each iteration optimizes the particle position and velocity and uses K-means and K-medoids recalculates cluster centers and cluster partitions until the end of the algorithm convergence iteration.After a lot of experimental analysis on the commonly used UCI data set,this paper not only solves the shortcomings of K-means clustering algorithm,the problem of dependence of the initial clustering center,and improves the accuracy of clustering,but also avoids falling into the local optimum.The algorithm has good global convergence. | Guorong Cui Hao Li Yachuan Zhang Rongjing Bu Yan Kang Jinyuan Li Yang Hu | 2020 | Journal of Quantum Computing2020，2，2： | 1 |
| 16 | Arterial stiffness blood pressure progression,and incident hypertension显示文摘 | Kaess BM RongJ Larson MG | 2012 | JAMA2012，308，： | 1 |
| 17 | Helical carbon nanotubes: Intrinsic peroxidase catalytic activity and its application for biocatalysis and biosensing显示文摘 | Cui Rongjing Han Zhida Zhu junjie | 2011 | Chemistry2011，17，34： | 1 |
| 18 | Grid-connected Photovoltaic Generation System显示文摘 | Wai Rongjing Wang Wenhang | 2008 | IEEE Transactions on Circuits and Systems2008，55，3： | 1 |
| 19 | Devel- opment of a heat shock inducible and inheritable RNAi system in silkworm 显示文摘 | Dai Hongjiu Jiang Rongjing Wang Jue | 2007 | Biomolecular Engineering2007，24，6： | 1 |
| 20 | RhoA/ROK pathway related to the mechanism of higher susceptibility to spasm in RA than in IMA 显示文摘 | Kun X Lefeng W Rongjing D | 2009 | J Card Surg2009，24，6： | 1 |
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