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| 1 | Initial Validation of Mobile-Structural Health Monitoring Method Using Smartphones显示文摘 | Yu Yan Han Ruicong Zhao Xuefeng | 2015 | International Journal of Distributed Sensor Networks2015，，： | 1 |
| 2 | A smart O_(2)-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy improving显示文摘Drug transportation is impeded by various barriers in the hypoxic solid tumor,resulting in compromised anticancer efficacy.Herein,a solid lipid monostearin(MS)-coated CaO_(2)/MnO_(2) nanocarrier was designed to optimize doxorubicin(DOX)transportation comprehensively for chemotherapy enhancement.The MS shell of nanoparticles could be destroyed selectively by highly-expressed lipase within cancer cells,exposing water-sensitive cores to release DOX and produce O_(2).After the cancer cell death,the core-exposed nanoparticles could be further liberated and continue to react with water in the tumor extracellular matrix(ECM)and thoroughly release O_(2) and DOX,which exhibited cytotoxicity to neighboring cells.Small DOX molecules could readily diffuse through ECM,in which the collagen deposition was decreased by O_(2)-mediated hypoxia-inducible factor-1 inhibition,leading to synergistically improved drug penetration.Concurrently,DOX-efflux-associated P-glycoprotein was also inhibited by O_(2),prolonging drug retention in cancer cells.Overall,the DOX transporting processes from nanoparticles to deep tumor cells including drug release,penetration,and retention were optimized comprehensively,which significantly boosted antitumor benefits. | Xiaojuan Zhang Chuanchuan He Yun Sun Xiaoguang Liu Yan Chen Chen Chen Ruicong Yan Ting Fan Tan Yang Yao Lu Jun Luo Xiang Ma Guangya Xiang | 2021 | Acta Pharmaceutica Sinica B2021，11，11： | 1 |
| 3 | A new method to prepare calcium oxalate films for marble protection显示文摘Artificial calcium oxalate films have been applied to protect sculptures,monuments,and buildings made of marble due to their potential protective capacities.Unfortunately,artificially prepared calcium oxalate films are usually loose,and easy to peel off in contrast to the natural ones.In this paper,a new method was developed for the preparation of a compact and cohesive calcium oxalate film,using ethylene glycol as an additive.The morphology,elemental composition,structure,and crystal phase of the film were analyzed by SEM,EDX,IR,and XRD,and the protective effects were investigated by acid resistance test,while its adhesion to the underlying marble by the Scotch tape test.The porosity,water absorption,and color of treated marble were also assessed.The results showed that a calcium oxalate film with a compact structure,good adhesion,and a protective effect against acid rain can be successfully obtained by including ethylene glycol as an additive.With the new preparation method,a better bond between the stone and the film is obtained which contributes to solving the spalling problem of the artificial calcium oxalate films. | HE Lu JIANG YiJie MA WenTing LIU Yan YANG FuWei LU RuiCong WANG Lu ZHANG Kun CHEN XinNan GAO Xiang | 2023 | Science China(Technological Sciences)2023，66，8： | 0 |
| 4 | Gradient-structure-enhanced dielectric energy storage performance of flexible nanocomposites containing controlled preparation of defective TiO_(2) and ferroelectric KNbO_(3) nanosheets显示文摘Next generation power system needs dielectrics with increased dielectric energy density.However,the low energy density of dielectrics limits their development.Here,an asymmetric trilayered nanocomposite,with a transition layer(TL),an insulation layer(IL),and a polarization layer(PL),is designed based on poly(vinylidene fluoride)-polymethyl methacrylate(PVDF-PMMA)matrix using KNbO_(3)(KN)and TiO_(2)(TO)as the nanofillers.The morphology and defect control of the two-dimensional nano KN and nano TO fillers are realized via a hydrothermal method to increase the composite breakdown strength(E_(b))and the composite energy density(U_(e)).The asymmetric trilayered structure leads to a gradient electric field distribution,and the KN and TO nanosheets block charges transfer along z direction.As a result,the development path of the electrical trees is greatly curved,and E_(b) is effectively improved.And the Ue value of the nanocomposites reaches 17.79 J·cm^(-3) at 523 MV·m^(-1).On the basis,the composite Ue is further improved by defect control in TO nanosheets.The nanocomposite KN/TO/PVDF-PMMA containing TO with less oxygen vacancy concentration(calcined at oxygen atmosphere)acquires a high Ue of 21.61 J·cm^(-3) at 548 MV·m^(-1).This study provides an idea for improving the energy storage performance by combining the design of the composite dielectric structure and the control of nanofillers’defect and morphology. | Yan Wang Lili Zhao Ruicong Chen Wenhui Zhao Dengwei Hu Haoran Wang Bin Cui | 2024 | Nano Research2024，17，5： | 0 |
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