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| 1 | CDP1, a novel component of chloroplast division site positioning system in Arabidopsis显示文摘叶绿体是从 endosymbiotic cyanobacteria 演变的植物特定的细胞器。他们通过二进制分裂划分。叶绿体部门地点的选择为对称的叶绿体部门是枢轴的。在 E。coli,在房间的中点部门地点放被 Min 系统的动态摆动调整,它包括 MinC,头脑和矿。在植物的头脑和矿的相当或相同的事物涉及叶绿体分割。MinC 的相当或相同的事物仍然没在更高的植物被识别。然而,象 FtsZ 一样蛋白质, ARC3,被发现地点放涉及叶绿体分割。这里,我们报导放 1 的那个叶绿体部门地点(AtCDP1 ) 是在 Arabidopsis 涉及叶绿体部门地点放置的新奇叶绿体部门蛋白质。AtCDP1 被与房间部门显型为殖民地在细菌屏蔽一个 Arabidopsis cDNA 表示图书馆发现。AtCDP1 只在 Arabidopsis 在年轻绿纸巾被表示。有多重部门地点的伸长的叶绿体在 loss-of-function cdp1 异种被观察。AtCDP1 的 Overexpression 也引起了一个叶绿体部门显型。蛋白质相互作用试金建议 AtCDP1 可以调停通过和 ARC3 的相互作用放的叶绿体部门地点。总的来说,我们的结果显示 AtCDP1 是放系统,和这个系统的工作机制的叶绿体部门地点的一个新奇部件与在原核生物的房间的传统的 MinCDE 系统的不同。 | Min Zhang Yong Hu Jingjing Jia Dapeng Li Runjie Zhang Hongbo Gao Yikun He | 2009 | Cell Research2009，19，7： | 5 |
| 2 | Antigenicity of tissues and organs from GGTA1/CMAH/β4GalNT2 triple gene knockout pigs显示文摘Clinical xenotransplantations have been hampered by human preformed antibody-mediated damage of the xenografts.To overcome biological incompatibility between pigs and humans,one strategy is to remove the major antigens[Gal,Neu5 Gc,and Sd(a)]present on pig cells and tissues.Triple gene(GGTAI,CMAH,and β4 GalNT2)knockout(TKO)pigs were produced in our laboratory by CRISPR-Cas9 targeting.To investigate the antigenicity reduction in the TKO pigs,the expression levels of these three xenoantigens in the cornea,heart,liver,spleen,lung,kidney,and pancreas tissues were examined.The level of human IgG/IgM binding to those tissues was also investigated,with wildtype pig tissues as control.The results showed that aGal,Neu5 Gc,and Sd(a)were markedly positive in all the examined tissues in wildtype pigs but barely detected in TKO pigs.Compared to wildtype pigs,the liver,spleen,and pancreas of TKO pigs showed comparable levels of human IgG and IgM binding,whereas corneas,heart,lung,and kidney of TKO pigs exhibited significantly reduced human IgG and IgM binding.These results indicate that the antigenicity of TKO pig is significantly reduced and the remaining xenoantigens on porcine tissues can be eliminated via a gene targeting approach. | Ronggen Wang Miaomiao Ruan Runjie Zhang Lei Chen Xiaoxue Li Bin Fang Chu Li Xueyang Ren Jiying Liu Qiang Xiong Lining Zhang Yong Jin Lin Li Rongfeng Li Ying Wang Haiyuan Yang Yifan Dai | 2019 | The Journal of Biomedical Research2019，33，4： | 3 |
| 3 | Effectof fenvalerate on the reproduction and fitness costs of thebrown planthopper, Nilaparvata lugens and its resistancemechanism 显示文摘 | LING Shanfeng ZHANG Hong ZHANG Runjie | 2011 | Pesticide Biochemistry and Physiology2011，101，： | 1 |
| 4 | Relationship between temperature and function response in Cardiochiles philippinesis (Hymenoptera:Braconidae),a larval parasitoid of Cnaphalocrocis medinalis(Lepidoptera:Pyrallidae)显示文摘 | Zhang Runjie | 1996 | Environmental Entomology1996，25，6： | 1 |
| 5 | Study on Transformation of Ideas of Environmental Protection Administration and Construction of Ecological Civilization in China显示文摘The transformation process of ideas of environmental protection administration in China was introduced firstly,and then the connotation and construction of ecological civilization were analyzed. | Fu Baorong Yang Tao He Zhe Zuo Shiwen Gu Chunyu Liu Song Zhang Runjie | 2017 | Meteorological and Environmental Research2017，8，3： | 1 |
| 6 | The advantages of crosstalk during the evolution of the BZR1–ARF6–PIF4 (BAP) module∞显示文摘The BAP module,comprising BRASSINAZOLE RESISTANT 1(BZR1),AUXIN RESPONSE FACTOR 6(ARF6),and PHYTOCHROME‐INTERACTING FACTOR 4(PIF4),functions as a molecular hub to orchestrate plant growth and development.In Arabidopsis thaliana,components of the BAP module physically interact to form a complex system that integrates light,brassinosteroid(BR),and auxin signals.Little is known about the origin and evolution of the BAP module.Here,we conducted comparative genomic and transcriptomic analyses to investigate the evolution and functional diversification of the BAP module.Our results suggest that the BAP module originated in land plants and that theζ,ε,andγwhole‐genome duplication/triplication events contributed to the expansion of BAP module components in seed plants.Comparative transcriptomic analysis suggested that the prototype BAP module arose in Marchantia polymorpha,experienced stepwise evolution,and became established as a mature regulatory system in seed plants.We developed a formula to calculate the signal transduction productivity of the BAP module and demonstrate that more crosstalk among components enables higher signal transduction efficiency.Our results reveal the evolutionary history of the BAP module and provide insights into the evolution of plant signaling networks and the strategies employed by plants to integrate environmental and endogenous signals. | Runjie Diao Mengru Zhao Yannan Liu Zhenhua Zhang Bojian Zhong | 2023 | Journal of Integrative Plant Biology2023，65，12： | 0 |
| 7 | Effects of Angelica Polysaccharide on telomere length in mice with benzene-induced aplastic anemia显示文摘Objective:To investigate the changes in telomere length and the level of burst-forming units-erythrocyte(BFU-Es)and colony-forming unit-erythrocytes(CFU-Es)in mice with benzene-induced aplastic anemia(AA),and follow-up the therapeutic effects of Angelica Polysaccharide(AP).Methods:Male BALB/c mice(n=120)were randomly divided into three groups(1,2,3):normal control(n=24),AA control(n=48),and treated AA(n=48),respectively.Mice in Group 2 received benzene inhalation for 2.5 months and 1 ml distilled water p.o.per day for 2 weeks after the establishment of AA models.Similar procedure was applied to the mice in Group 3 and AP was given for 2 weeks after the establishment of AA models.Real-time polymerase chain reaction was used to survey relative telomere length measurement of the bone marrow cells.A BFU-Es and CFU-Es survey was done to follow-up the therapeutic effects of AP.Results:Compared with normal control,significant reductions of RBC,WBC,and platelet counts were found in peripheral blood of AA mice.After treatment with AP,counts of BFU-Es and CFU-Es were restored up to 66.8%and 77.25%,respectively,and length of telomere was restored up to 76.34%,of the normal levels.The telomere length in treated AA group was higher than the control AA group.Conclusion:The AP can protect the telomere length and differentiation of hemopoietic stem/progenitor cells,accelerate the recovery of BFU-Es and CFU-Es of AA mice,and then improve the bone marrow failure. | Runjie Sun Xing Cui Qingsong Wang Yanyu Zhang Xiaoqi Sun | 2020 | TMR Modern Herbal Medicine2020，3，1： | 0 |
| 8 | Transfer of a eubacteria-type cell division site-determining factor CrMinD gene to the nucleus from the chloroplast genome in Chlamydomonas reinhardtii显示文摘MinD is a ubiquitous ATPase that plays a crucial role in selection of the division site in eubacteria, chloroplasts, and probably Archaea. In four green algae, Mesostigma viride, Nephroselmis olivacea, Chlorella vulgaris and Prototheca wickerhamii, MinD homologues are encoded in the plastid genome. However, in Arabidopsis, MinD is a nucleus-encoded, chloroplast-targeted protein involved in chloro- plast division, which suggests that MinD has been transferred to the nucleus in higher land plants. Yet the lateral gene transfer (LGT) of MinD from plastid to nucleus during plastid evolution remains poorly understood. Here, we identified a nucleus-encoded MinD homologue from unicellular green alga Chlamydomonas reinhardtii, a basal species in the green plant lineage. Overexpression of CrMinD in wild type E. coli inhibited cell division and resulted in the filamentous cell formation, clearly demon- strated the conservation of the MinD protein during the evolution of photosynthetic eukaryotes. The transient expression of CrMinD-egfp confirmed the role of CrMinD protein in the regulation of plastid division. Searching all the published plastid genomic sequences of land plants, no MinD homologues were found, which suggests that the transfer of MinD from plastid to nucleus might have occurred be- fore the evolution of land plants. | LIU WeiZhong HU Yong ZHANG RunJie ZHOU WeiWei ZHU JiaYing LIU XiangLin HE YiKun | 2007 | Chinese Science Bulletin2007，52，18： | 0 |
| 9 | Large sequence models for sequential decision-making:a survey显示文摘Transformer architectures have facilitated the development of large-scale and general-purpose sequence models for prediction tasks in natural language processing and computer vision,e.g.,GPT-3 and Swin Transformer.Although originally designed for prediction problems,it is natural to inquire about their suitability for sequential decision-making and reinforcement learning problems,which are typically beset by long-standing issues involving sample efficiency,credit assignment,and partial observability.In recent years,sequence models,especially the Transformer,have attracted increasing interest in the RL communities,spawning numerous approaches with notable effectiveness and generalizability.This survey presents a comprehensive overview of recent works aimed at solving sequential decision-making tasks with sequence models such as the Transformer,by discussing the connection between sequential decision-making and sequence modeling,and categorizing them based on the way they utilize the Transformer.Moreover,this paper puts forth various potential avenues for future research intending to improve the effectiveness of large sequence models for sequential decision-making,encompassing theoretical foundations,network architectures,algorithms,and efficient training systems. | Muning WEN Runji LIN Hanjing WANG Yaodong YANG Ying WEN Luo MAI Jun WANG Haifeng ZHANG Weinan ZHANG | 2023 | Frontiers of Computer Science2023，17，6： | 0 |
| 10 | Response Mechanism of Water Ecosystem under the Influence of Urbanization: A Case Study of the Connection Zone between Shenyang and Fushun显示文摘Taking the connection zone between Shenyang and Fushun as an example,urbanization indicator system was established from the aspects of population,economy,space and society,and the comprehensive evaluation indicator system of water ecological environment was also established from the aspects of water ecological environmental pressure,state and response. Based on the evaluation of comprehensive level of urbanization and the comprehensive quality of water ecological environment,their changing trends during 2000-2014 were analyzed,and the response model between them was established. The composite index of urbanization in the connection zone between Shenyang and Fushun always increased from 2000 to 2014,and urbanization developed rapidly after 2004. The comprehensive quality of water ecological environment decreased firstly and then increased during 2000-2014. The response relationship between urbanization comprehensive index and water ecological comprehensive index during 2000-2014 could be expressed by a cubic curve. | Zhang Runjie Gu Chunyu Zuo Shiwen Qi Yue Tong Lili Fu Baorong | 2018 | Meteorological and Environmental Research2018，9，5： | 0 |
| 11 | Linear stability theory with the equivalent spanwise wavenumber correction in 3D boundary layers显示文摘The prediction on small disturbance propagation in complex three-dimensional(3D) boundary layers is of great significance in transition prediction methodology, especially in the aircraft design. In this paper, the linear stability theory(LST) with the equivalent spanwise wavenumber correction(ESWC) is proposed in order to accurately predict the linear evolution of a disturbance in a kind of boundary layer flow with a vital variation in the spanwise direction. The LST with the ESWC takes not only the scale of the mean flow with the significant variation but also the wavenumber evolution of the disturbance itself. Compared with the conventional LST, the results obtained by the new method are in excellent agreement with those of the numerical simulations. The LST with the ESWC is an effective method on the prediction of the disturbance evolution in 3D boundary layers, which improves the prediction of the LST in the applications to complex 3D boundary layers greatly. | Runjie SONG Shaolong ZHANG Jianxin LIU | 2019 | Applied Mathematics and Mechanics(English Edition)2019，40，3： | 0 |
| 12 | Origin and evolution of green plants in the light of key evolutionary events显示文摘Green plants(Viridiplantae)are ancient photosynthetic organisms that thrive both in aquatic and terrestrial ecosystems,greatly contributing to the changes in global climates and ecosystems.Significant progress has been made toward understanding the origin and evolution of green plants,and plant biologists have arrived at the consensus that green plants first originated in marine deep-water environments and later colonized fresh water and dry land.The origin of green plants,colonization of land by plants and rapid radiation of angiosperms are three key evolutionary events during the long history of green plants.However,the comprehensive understanding of evolutionary features and molecular innovations that enabled green plants to adapt to complex and changeable environments are still limited.Here,we review current knowledge of phylogenetic relationships and divergence times of green plants,and discuss key morphological innovations and distinct drivers in the evolution of green plants.Ultimately,we highlight fundamental questions to advance our understanding of the phenotypic novelty,environmental adaptation,and domestication of green plants. | Zhenhua Zhang Xiaoya Ma Yannan Liu Lingxiao Yang Xuan Shi Hao Wang Runjie Diao Bojian Zhong | 2022 | Journal of Integrative Plant Biology2022，64，2： | 0 |
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