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| 1 | Function of shoulder muscles of driver in vehicle steering maneuver显示文摘In order to study the function of muscles of driver shoulder during vehicle steering, identification of relations between electromyograph (EMG) activity of 10 shoulder muscles and steering force was performed. The procedure was to perform controlled steering maneuver by right hand in a driving simulator, and based on analyzing the EMG data with steering force in the steering wheel plane, the function was identified. It was found that muscle function depends strongly on both steering rotation and steering torque directions. In clockwise steering, the long head of triceps brachii was the prime mover and an important contributor to clockwise moment, while the sternocostal portion of the pectoralis major, the lateral head of triceps brachii, biceps brachii and teres major were the important stabilizers or fixators. In contrast, in counterclockwise steering, the anterior, middle and posterior deltoid, the clavicular portion of the pectoralis major and infraspinatus were the prime movers and also the important contributors to counterclockwise moment, while the sternocostal portion of the pectoralis major, the lateral head of triceps brachii, biceps brachii and teres major were the important stabilizers or fixators. We conclude that the prime movers are primarily a consequence of steering direction, while the stabilizers or fixators are primarily constant. These results can be used to improve the neuromuscular model and estimate the steering comfort of driver. | LIU YaHui JI XueWu RYOUHEI Hayama TAKAHIRO Mizuno LOU LiMing | 2012 | Science China(Technological Sciences)2012，55，12： | 12 |
| 2 | A Novel Estimating Method for Steering Efficiency of the Driver with Electromyography Signals显示文摘The existing research of steering efficiency mainly focuses on the mechanism efficiency of steering system,aiming at designing and optimizing the mechanism of steering system.In the development of assist steering system especially the evaluation of its comfort,the steering efficiency of driver physiological output usually are not considered,because this physiological output is difficult to measure or to estimate,and the objective evaluation of steering comfort therefore cannot be conducted with movement efficiency perspective.In order to take a further step to the objective evaluation of steering comfort,an estimating method for the steering efficiency of the driver was developed based on the research of the relationship between the steering force and muscle activity.First,the steering forces in the steering wheel plane and the electromyography(EMG)signals of the primary muscles were measured.These primary muscles are the muscles in shoulder and upper arm which mainly produced the steering torque,and their functions in steering maneuver were identified previously.Next,based on the multiple regressions of the steering force and EMG signals,both the effective steering force and the total force capacity of driver in steering maneuver were calculated.Finally,the steering efficiency of driver was estimated by means of the estimated effective force and the total force capacity,which represented the information of driver physiological output of the primary muscles.This research develops a novel estimating method for driver steering efficiency of driver physiological output,including the estimation of both steering force and the force capacity of primary muscles with EMG signals,and will benefit to evaluate the steering comfort with an objective perspective. | LIU Yahui JI Xuewu HAYAMA Ryouhei MIZUNO Takahiro | 2014 | Chinese Journal of Mechanical Engineering2014，27，3： | 4 |
| 3 | Randomized phase II study of gemcitabine and S-1 combination versus gemcitabine alone in the treatment of unresectable advanced pancreatic cancer (Japan Clinical Cancer Research Organization PC-01 study)显示文摘 | Masato Ozaka Yuji Matsumura Hiroshi Ishii Yasushi Omuro Takao Itoi Hisatsugu Mouri Keiji Hanada Yasutoshi Kimura Iruru Maetani Yoshinobu Okabe Masaji Tani Takaaki Ikeda Susumu Hijioka Ryouhei Watanabe Shinya Ohoka Yuki Hirose Masafumi Suyama Naoto Egawa A | 2012 | Cancer Chemotherapy and Pharmacology2012，，5： | 3 |
| 4 | Rapid Ventricular Induction of Brain Natriuretic Peptide Gene Expression in Experimental Acute Myocardial Infarction显示文摘 | Norio Hama Hiroshi Itoh Gotaro Shirakami Osamu Nakagawa Shin-ichi Suga Yoshihiro Ogawa Izuru Masuda Kuniaki Nakanishi Takaaki Yoshimasa Yukiya Hashimoto Masayuki Yamaguchi Ryouhei Hori Hirofumi Yasue Kazuwa Nakao | 1995 | Circulation1995，，6： | 1 |
| 5 | Mendel's green coty- ledon gene encodes a positive regulator of the chlorophyll-de- grading pathway 显示文摘 | Yutaka S Ryouhei M Minoru N | 2007 | Proceedings of the National Academy of Sciences of the United States of America2007，104，14： | 1 |
| 6 | Biological activity of the Helicobacter priori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites显示文摘 | Hideaki H Ryouhei T Akiko F | 2002 | Proc Natl Acad Sci2002，99，14： | 1 |
| 7 | Polypropylene Laminated Steel Sheet Usable without Painting显示文摘 | Yoshihara Ryoichi Wake Ryousuke Mizoguchi Ryouhei | 2000 | Nippon Steel Technical Report2000，，81： | 1 |
| 8 | Treatment of the unstable distal radius fracture with external fixation and a hydroxyapatite spacer显示文摘 | Hiroaki Sakano Tomihisa Koshino Ryouhei Takeuchi Naotaka Sakai Tomoyuki Saito | 2001 | Journal of Hand Surgery2001，，： | 1 |
| 9 | Effect of bilingualism on cognitive control in the Simon task: evidence from MEG显示文摘 | Ellen Bialystok Fergus I.M. Craik Cheryl Grady Wilkin Chau Ryouhei Ishii Atsuko Gunji Christo Pantev | 2004 | Neuroimage2004，，1： | 1 |
| 10 | Fault-tolerant automobile steering based on diversity of steer-by-wire, braking and acceleration显示文摘 | Ryouhei Hayama Masayasu Higashi Sadahiro Kawahara Shirou Nakano Hiromitsu Kumamoto | 2009 | Reliability Engineering and System Safety2009，，1： | 1 |
| 11 | Synchronous Cancer of the Biliary Tract and Pancreas Associated with Anomalous Arrangement of the Pancreaticobiliary Ductal System显示文摘 | Nobuhiko Ueda Takukazu Nagakawa Tetsuo Ohta Masato Kayahara Keiichi Ueno Ichiroh Konishi Ryouhei Izumi Itsuo Miyazaki | 1992 | Journal of Clinical Gastroenterology1992，，2： | 1 |
| 12 | Two short-chain dehydro- genase/reductases,non-yellow coloring 1 and NYCl-like,are re- quired for chlorophyll band light-harvesting complex II degrada- tion during senescence in rice显示文摘 | Yutaka S Ryouhei M Susumu K | 2009 | Plant J2009，57，： | 1 |
| 13 | Mendel's green cotyledon gene encodes a positive regulator of the chlorophyll-degrading pathway显示文摘 | Yutaka S Ryouhei M Minoru N | 2007 | PNAS2007，104，14： | 1 |
| 14 | Defect in non-yellow coloring 3,an a/b hydrolase-fold family protein, causes a stay-green phe- notype during leafseneseence in rice 显示文摘 | Ryouhei M Yutaka S Yu M | 2009 | Plant J2009，59，： | 1 |
| 15 | Structure-function relationships of soybean proteins revealed by using recombinant systems显示文摘 | Shigeru Utsumi Nobuyuki Maruyama Ryouhei Satoh Motoyasu Adachi | 2002 | Enzyme and Microbial Technology2002，，3： | 1 |
| 16 | Fault- tolerant Automobile Steering Based on Diversity of Steer-by-Wire, Braking and Acceleration 显示文摘 | Ryouhei Hayama Masayasu Higashi Sadahiro Kawahara | 2010 | Reliability Engineering & System Safety2010，95，1： | 1 |
| 17 | Rapid Ventricular Induction of Brain Natriuretic Peptide Gene Expression in Experimental Acute Myocardial Infarction显示文摘 | Norio Hama Hiroshi Itoh Gotaro Shirakami Osamu Nakagawa Shin-ichi Suga Yoshihiro Ogawa Izuru Masuda Kuniaki Nakanishi Takaaki Yoshimasa Yukiya Hashimoto Masayuki Yamaguchi Ryouhei Hori Hirofumi Yasue Kazuwa Nakao | 1995 | Circulation1995，，6： | 1 |
| 18 | Fault-tolerant automobile steering,based on diversity of steer-by-wire,braking and acceleration显示文摘 | Ryouhei Hayama Masayasu Higashi Sadahiro Kawahara | | 0，，1： | 1 |
| 19 | Distant metastasis of hepatocellular carcinoma to Meckel’s cave and cranial nerves:A case report and review of literature显示文摘BACKGROUND Metastasis occurs as a late event in the natural history of hepatocellular carcinoma(HCC),and most patients die of liver failure attributed to the tumor supplanting the liver.Conversely,the brain is a less common metastatic site.CASE SUMMARY We describe a rare case of hepatitis C virus-related multiple HCC metastasizing to the cavernous sinus,Meckel’s cave,and the petrous bone involving multiple cranial nerves in an 82-year-old woman.At admission imaging studies including Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging(MRI)revealed multiple HCC nodules in both right and left lobes.Ultrasound guided biopsy of the left lobe revealed moderately differentiated HCC.Molecular targeted therapy with Lenvatinib(8 mg/d for 94 d,per os)and Ramucirumab(340 mg/d and 320 mg/d,two times by intravenous injection)were administered for 4 mo,resulting in progression of the disease.Three months after the start of molecular target therapy,the patient presented with symptoms of hyperalgesia of the right face and limited abduction of the right eye,indicating disturbances in the right trigeminal and abducens nerves.Brain MRI disclosed a mass involving the cavernous sinus,Meckel’s cave and the petrous bone.Contrast-enhanced MRI with gadolinium-chelated contrast medium revealed a well-defined mass with abnormal enhancement around the right cavernous sinus and the right Meckel’s cave.CONCLUSION The diagnosis of metastatic HCC to the cavernous sinus,Meckel’s cave,and the petrous bone was made based on neurological findings and imaging studies including MRI,but not on histological examinations.Further studies may provide insights into various methods for diagnosing HCC metastasizing to the craniospinal area. | Soo Ki Kim Takako Fujii Ryouhei Komaki Hisato Kobayashi Toyokazu Okuda Yumi Fujii Takanobu Hayakumo Kanako Yuasa Masahiro Takami Aya Ohtani Yuka Saijo Yu-Ichiro Koma Soo Ryang Kim | 2021 | World Journal of Hepatology2021，13，6： | 0 |
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