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| 1 | Program design of on-line fault diagnosis for ASCS of AMT in a heavy-duty vehicle显示文摘 | Liu Haiou Zeng Ai Song Weiqun | 2011 | Applied Mechanics and Materials2011，109，： | 1 |
| 2 | Effects of diazepam on glutamatergic synaptic transmission in the hippocampal CA1 area of rats with traumatic brain injury显示文摘The activity of the Schaffer collaterals of hippocampal CA3 neurons and hippocampal CA1 neurons has been shown to increase after fluid percussion injury. Diazepam can inhibit the hyperexcitability of rat hippocampal neurons after injury, but the mechanism by which it affects excitatory synaptic transmission remains poorly understood. Our results showed that diazepam treatment significantly increased the slope of input-output curves in rat neurons after fluid percussion injury. Diazepam significantly decreased the numbers of spikes evoked by super stimuli in the presence of 15 μmol/L bicuculline, indicating the existence of inhibitory pathways in the injured rat hippocampus. Diazepam effectively increased the paired-pulse facilitation ratio in the hippocampal CA1 region following fluid percussion injury, reduced miniature excitatory postsynaptic potentials, decreased action-potential-dependent glutamine release, and reversed spontaneous glutamine release. These data suggest that diazepam could decrease the fluid percussion injury-induced enhancement of excitatory synaptic transmission in the rat hippocampal CA1 area. | Lei Cao Xiaohua Bie Su Huo Jubao Du Lin Liu Weiqun Song | 2014 | Neural Regeneration Research2014，9，21： | 1 |
| 3 | The role of different cues in the brain mechanism on visual spatial attention显示文摘在大脑的视觉空间注意机制被事件相关的潜力(ERP ) 通过 precue 目标的视觉搜索范例在 16 个年轻题目学习技术,与由汉字和区域暗示的不同规模的专心的范围 cued。结果证明汉字暗示的反应时间为小区域暗示特别为区域暗示比那长得多。与外面的干扰,在区域暗示下面的目标刺激识别在汉字暗示下面是比那快得多的。与相比在区域暗示下面,在汉字暗示下面的目标能导致以后的 P1 的增加, N1 减少并且 P2 增加。区域暗示和汉字暗示之间的差别被干扰类型影响,这应该也被注意。在外面的干扰下面,没有重要差别在区域暗示和汉字暗示之间被发现;然而,它不是在干扰下面的原因。就外面的干扰和内部干扰之间的差别而言,我们能断定随在目标识别的困难的增加,在由在二种暗示下面的目标刺激的前面的正面的资源的消费有明显的差别。 | SONG Weiqun LUO Yuejia CHI Song JI Xunming LING Feng ZHAO Lun WANG Maobin SHI Jiannong | 2006 | Progress in Natural Science:Materials International2006，16，10： | 1 |
| 4 | Effects of Early Infection of Tobacco Mosaic Virus on Photosynthetic Proteins and Its Control显示文摘[Objectives] This study was conducted to explore the optimal period of TMV control and the physiological sites that interfere with TMV infection. [Methods] Proteome analysis was performed on the host tissues(tobacco plants) at different time periods of viral infection, to verify the changes in the expression of differential protein genes and N and PR1-a in the photosynthetic pathway and porphyrin metabolism and chlorophyll metabolism pathways in proteome; and the tobacco plants were treated with different preparations. [Results] The expression levels of N and PR1-a in the tobacco leaves treated with preparation B reached the highest level, and the effects on the expression levels of the differential protein genes were also the most significant. The control effects of the preparations were tested by the half-leaf method, and the results showed that preparation B had a significant control effect against the early infection of the virus.[Conclusions] This study lays a foundation for the prevention and control of tobacco mosaic virus on crops. | Xiaojing XU Kunfeng SONG Fengsheng HAO Jiajia ZHAO Hongxiang GUO Weiqun LIU | 2019 | Agricultural Biotechnology2019，8，2： | 0 |
| 5 | Repetitive training for ameliorating upper limbs spasm of hemiplegic patients显示文摘BACKGROUND:The main aim of rehabilitation is to ameliorate motor function and use the damaged limbs in the activities of daily living.Several factors are needed in the self-recovery of the patients,and the most important one is to reduce spasm.Some mechanical repetitive movements can affect and change the excitability of motor neurons.OBJECTIVE:To observe the effect of repetitive training on ameliorating spasm of upper limbs of hemiplegic patients.DESIGN:A self-controlled observation before and after training.SETTING:Department of Rehabilitation,Xuanwu Hospital of Capital Medical University.PARTICI PANTS: Seven hemiplegic patients induced by brain injury were selected from the Department of Rehabilitation,Xuanwu Hospital,Capital Medical University from March to June in 2005.Inclusive criteria:①Agreed and able to participate in the 30-minute training of hand function; ②Without disturbance of understanding.The patients with aphasia or apraxia,manifestation of shoulder pain,and severe neurological or mental defects.For the 7 patients,the Rivermead motor assessment(RMA)scores ranged 0-10 points,the Rivermead mobility index(RMI)ranged 1-3,and modified Ashworth scale(MAS)was grade 2-4.Their horizontal extension of shoulder joint was 0°-30°,anteflextion was 0°-50°,internal rotation was 50°-90°,external rotation was 0°-10°:and the elbow joint could extend for 15°-135°.METHODS:The viva 2 serial MOTOmed exerciser(Reck Company,Germany)was used.There were three phases of A-B-A.①The phase A lasted for 1 week.The patient sat on a chair facting to the MOTOmed screen.and did the circumduction of upper limbs forwardly,30 minutes a day and 5 days a week.②The phase B lasted for 3 weeks.The training consisted of forward circumduction of upper limbs for 15 minutes.followed by backward ones for 15 minutes and 5-minute rest.③The training in the phase A was performed again for 2 weeks.The extensions of upper limbs were recorded at phase A,the extension and flexion of elbow joints were recorded at phase B,and the extensions were recorded at the second A phase.All the patients were evaluated by the same therapeutist.①RMA was used to evaluate the motor function completely,including the motor control of both upper and lower limbs,but only the data of upper limbs were recommended to be used. Tne flexibility and concordance of upper limbs were described by detecting the ability of hand to move objects with 15 items,2 grades for each item:0 for could not complete and 1 for could complete.②RMI was used to measure the flexion and extension of elbow joint and shoulder joint,the scores ranged from 0(no movement and no obvious muscle contraction)to 5(close to normal movement).③MAS was used to evaluate the muscle tension in clinic.Grade 1 for without abnormal increase of muscle tension,and grade 5 for muscle rigidity.and it was unable for passive movement.④Ranges of motion of elbow joint and should joint were measured using protractor.MAIN OUTCOME MEASURES:①The strength of each limb to persist for 40 s recorded by two hand pedals;②Changes of muscle tensions detected by the two hand pedals;③Changes of muscle contraction at the flexion and extension of ipsilateral limb recorded by EMG;④Minimal moment of iplateral end foot;⑤RMA;⑥RMI;⑦MAS;⑧Ranges of motion of elbow joints and shoulder joints.RESULTS:The functions were evaluated at 6 weeks after training.①The strength of each limb to persist for 40 s was recorded.and the strength of the ipsilateral limb changed obviously from 20%-40%to 50%-70%.②The muscle tensions detected by the two hand pedals changed from 2.2-4.0 N·m to 0.2-1.0 N·m.③EMG displayed that along with the enhancement of fast movements.the strength curve increased(the EMG for the extension of elbow joints were obvious).④The minimal moment of iplateral end foot was 5.0 N·m.⑤The RMA scores ranged 15-30 points.⑥The RMI ranged 4-5.⑦MAS were grades 0-2.⑧For shoulder joints,the ranges of motion were 90°-180°for external extension,90°for anteflexion,90°for internal rotation and 50°-75°for external rotation;For elbow joints,the extension of active movements was close to 0°.CONCLUSION:After repetitive movements,the strength of upper limb increased,the range of motion enlarged,and spasm reduced. | Lin Zhu Lin Liu Weiqun Song | 2006 | Neural Regeneration Research2006，1，7： | 0 |
| 6 | Design, Synthesis and Antifungal Activity of Novel Thioureas Containing 1,3,4-Thiadiazole and Thioether Skeleton显示文摘 | WANG Caixia SONG Hailong LIU Weiqun XU Cuilian | 2016 | Chemical Research in Chinese Universities2016，32，4： | 0 |
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