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| 1 | Deformation response of roof in solid backfilling coal mining based on viscoelastic properties of waste gangue显示文摘Solid backfill mining(SBM)is a form of green mining,the core of which is to control and minimize the deformation and movement of strata above longwall coal mines.Establishing a mechanical model that can reliably describe roof deformation by considering the viscoelastic properties of waste gangue is important as it assists in improving mine designs and reducing the environmental impact on the surface.In this paper,the time-dependent deformation characteristics of gangue under different stress levels were obtained by using lateral confinement compression,that reliably represents the compaction of goaf.The viscoelastic foundation model for gangue mechanical response is different from the traditionally used elastic foundation model,as it considers the time factor and viscoelasticity.A mechanical model using a thin plate on a fractional viscoelastic foundation was established,and the roof deflection,bending moment,time-dependent,viscous and other characteristics of SBM were included and analyzed.Compared with the existing elastic foundation model,the proposed fractional order viscoelastic foundation model has higher accuracy with laboratory data.The plate deflection increases by 50.9%and the bending moment increases by 37.9%after 100 days,which the elastic model would not have been able to predict. | Peng Huang Jixiong Zhang Xingjie Yan Anthony John Spencer Spearing Meng Li Shiwei Liu | 2021 | International Journal of Mining Science and Technology2021，31，2： | 8 |
| 2 | Genesis of the Bianjiadayuan Pb-Zn polymetallic deposit, Inner Mongolia, China:Constraints from in-situ sulfur isotope and trace element geochemistry of pyrite显示文摘The Southern Great Xing’an Range (SGXR) which forms part of the eastern segment of the Central Asian Orogenic Belt (CAOB) is known as one of the most important Cu-Mo-Pb-Zn-Ag-Au metallogenic belts in China,hosting a number of porphyry Mo (Cu),skarn Fe (Sn),epithermal Au-Ag,and hydrothermal veintype Ag-Pb-Zn ore deposits.Here we investigate the Bianjiadayuan hydrothermal vein-type Ag-Pb-Zn ore deposit in the southern part of the SGXR.Porphyry Sn ±Cu ± Mo mineralization is also developed to the west of the Ag-Pb-Zn veins in the ore field.We identify a five-stage mineralization process based on field and petrologic studies including (i) the early porphyry mineralization stage,(ii) main porphyry mineralization stage,(iii) transition mineralization stage,(iv) vein-type mineralization stage and (v) late mineralization stage.Pyrite is the predominant sulfide mineral in all stages except in the late mineralization stage,and we identify corresponding four types of pyrites: Py1 is medium-grained subhedral to euhedral occurring in the early barren quartz vein;Py2 is medium- to fine-grained euhedral pyrite mainly coexisting with molybdenite,chalcopyrite,minor sphalerite and galena;Py3 is fine-grained,subhedral to irregular pyrite and displays cataclastic textures with micro-fractures;Py4 occurs as euhedral microcrystals and forms irregularly shaped aggregate with sphalerite and galena.LA-ICP-MS trace element analyses of pyrite show that Cu,Pb,Zn,Ag,Sn,Cd and Sb are partitioned into pyrite as structurally bound metals or mineral micro/nano-inclusions,whereas Co,Ni,As and Se enter the lattice via isomorphism in all types of pyrite.The Cu,Zn,Ag,Cd concentrations gradually increase from Py1 to Py4,which we correlate with cooling and mixing of ore-forming fluid with meteoric water.Py2 contains the highest contents of Co,Ni,Se,Te and Bi,suggesting high temperature conditions for the porphyry mineralization stage.Ratios of Co/Ni (0.03-10.79,average 2.13) and sulphur isotope composition of sulfide indicate typical hydrothermal origin for pyrites.The δ^34SCDT values of Py1 (0.42‰-1.61‰,average 1.16‰),Py2 (-1.23‰ to 0.82‰,average 0.35‰),Py3 (-0.36‰ to 2.47‰,average 0.97‰),Py4 (2.51‰-3.72‰,average 3.06‰),and other sulfides are consistent with those of typical porphyry deposit (-5‰ to 5‰),indicating that the Pb-Zn polymetallic mineralization in the Bianjiadayuan deposit is genetically linked to the Yanshanian (JurassiceCretaceous) magmatic-hydrothermal events.Variations of d34S values are ascribed to the changes in physical and chemical conditions during the evolution and migration of the ore-forming fluid.We propose that the high Sn content of pyrite in the Bianjiadayuan hydrothermal vein-type PbeZn polymetallic deposit can be used as a possible pathfinder to prospect for Sn mineralization in the surrounding area or deeper level of the ore field in this region. | Kai-Rui Song Li Tang Shou-Ting Zhang M. Santosh Christopher J. Spencer Yu Zhao Hao-Xing Li Liang Wang An-Li Zhang Yin-Qiang Sun | 2019 | Geoscience Frontiers2019，10，5： | 4 |
| 3 | The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells显示文摘 | William J. Harris Xu Huang James T. Lynch Gary J. Spencer James R. Hitchin Yaoyong Li Filippo Ciceri Julian G. Blaser Brigit F. Greystoke Allan M. Jordan Crispin J. Miller Donald J. Ogilvie Tim C.P. Somervaille | 2012 | Cancer Cell2012，，4： | 2 |
| 4 | Comparative efficacy of fibrinogen and platelet supplementation on the in vitro reversibility of competitive glycoprotein Ⅱb/Ⅲa receptor-directed platelet inhibition显示文摘 | Li YF Spencer FA Becker RC | 2002 | Am Heart J2002，143，： | 1 |
| 5 | Lathyrus Sativus (Grass Pea) and Its Neurotoxin ODAP显示文摘 | Yah Z Y Spencer P S Li Z X | 2006 | Phytochemistry2006，，67： | 1 |
| 6 | Estrogen regulation of trefoil factor 1 expression by estrogen receptor alpha and Sp proteins显示文摘 | SUN J M SPENCER V A LI L | 2005 | Exp Cell Res2005，302，： | 1 |
| 7 | Effect of Non-Proportional Damping on Seismic Isolation 显示文摘 | Du Yongfeng Li Hui Spencer Jr | 2002 | Journal of Structural Control2002，9，3： | 1 |
| 8 | Miglitol:a review of its therapentic potential in type 2 diabetes meIlitus显示文摘 | Scott LI Spencer CM | 2000 | Drugs2000，59，3： | 1 |
| 9 | Effect of non-proportional damping on seismic isolation 显示文摘 | DU Yongfeng LI Hui SPENCER B F Jr | 2002 | Journal of Structural Control2002，9，3： | 1 |
| 10 | Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1‐ and TCF‐dependent Mechanisms显示文摘 | Elsayed E. Ibrahim Roya Babaei‐Jadidi Anas Saadeddin Bradley Spencer‐Dene Sina Hossaini Mohammed Abuzinadah Ningning Li Wakkas Fadhil Mohammad Ilyas Dominique Bonnet Abdolrahman S. Nateri | 2012 | STEM CELLS2012，，10： | 1 |
| 11 | Seismic Performance of Double-Layer Spherical Reticulated Shell with Replaceable Bar-Type Dampers显示文摘 | Yang Yang Bill F. Spencer Youming Li Shizhao Shen | 2011 | International Journal of Space Structures2011，，1： | 1 |
| 12 | Impacts of amino acid nutrition on pregnancy outcome in pigs:mechanisms and implications for swine production显示文摘 | Wu G Bazer FW Burghardt RC Johnson GA Kim SW Li XL Satterfield MC Spencer TE | | 0，，13： | 1 |
| 13 | High fat feeding and dietary l-arginine supplementation differentially regulate gene expression in rat white adipose tissue显示文摘 | Wenjuan Jobgen Wenjiang J. Fu Haijun Gao Peng Li Cynthia J. Meininger Stephen B. Smith Thomas E. Spencer Guoyao Wu | 2009 | Amino Acids2009，，1： | 1 |
| 14 | SARS-CoV-2 productively infects primary human immune system cells in vitro and in CoviD-19 patients显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CovV-2)infection is associated with a hyperinflammatory state and lymphocytopenia,a hallmark that appears as both signature and prognosis of disease severity outcome.Although cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion,it is still unclear whether direct SARS-Cov-2 infection of immune cells could also play a role in this scenario by harboring viral replication.We found that monocytes,as well as both B and T lymphocytes,were susceptible to SARS-Cov-2 infection in vitro,accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive T cell apoptosis.In addition,flow cytometry and immunofluorescence analysis revealed that SARS-Cov-2 was frequently detected in monocytes and B lymphocytes from coronavirus disease 2019(CoVID-19)patients.The rates of SARS-Cov-2-infected monocytes in peripheral blood mononuclear cells from CoVID-19 patients increased over time from symptom onset,with SARS-CoV-2-positive monocytes,B cells,and CD4+T lymphocytes also detected in postmortem lung tissue.These results indicated that SARS-CoV-2 infection of blood-circulating leukocytes in covID-19 patients might have important implications for disease pathogenesis and progression,immune dysfunction,and virus spread within the host. | Marjorie C.Pontelli italo A.Castro Ronaldo B.Martins Leonardo La Serra Flavio P.Veras Daniele C.Nascimento Camila M.Silva Ricardo S.Cardoso Roberta Rosales Rogério Gomes Thais M.Lima Juliano P.Souza Brenda C.Vitti Diego B.Caetite Mikhael H.F.de Lima Spencer D.Stumpf Cassandra E.Thompson Louis-Marie Bloyet Juliana E Toller-Kawahisa Marcela C.Giannini Leticia P.Bonjorno Marial.F.Lopes Sabrina S.Batah Li Siyuan Rodrigo Luppino-Assad Sergio C.L.Almeida Fabiola R.Oliveira Maira N.Benatti Lorena L.F.Pontes Rodrigo C.Santana Fernando C.Vilar Maria Auxiliadora-Martins Pei-Yong Shi Thiago M.Cunha Rodrigo T.Calado JoséC.Alves-Filho Dario S.Zamboni Alexandre T.Fabro Paulo Louzada-Junior Rene D.R.Oliveira Sean P.J.Whelan Fernando Q.Cunha Eurico Arruda | 2022 | Journal of Molecular Cell Biology2022，14，4： | 1 |
| 15 | Ferry,role of dissolved organic matter,nitrate,and bicarbonate in the photolysis of aqueous gipronil environ显示文摘 | SPENCER S WALSE STEPHEN L MORGAN LI KONG | 2004 | Sci Technol2004，38，： | 1 |
| 16 | Effect of non-pro- portional damping on seismic isolation显示文摘 | DU Yong feng LI Hui SPENCER B F | 2002 | journal of Struc- tural Control2002，9，3： | 1 |
| 17 | Role of dissolved organic matter, nitrate and bicarbonate in the pho- tolysis of aqueous fipronil显示文摘 | Spencer S Walse Stephen L Morgan Li Kong | 2004 | Environmental Science and Technology2004，38，： | 1 |
| 18 | Comparative effects of unfractionated heparin and low molecular weight heparin on vascular endothelial cell tissue factor pathway inhibitor release:a model for assessing intrinsic thromboresistance显示文摘 | Li Y Rodriquez M Spencer FA | 2002 | J Thromb Thrombolysis2002，14，2： | 1 |
| 19 | Arginine metabolism and nutrition in growth, health and disease显示文摘 | Guoyao Wu Fuller W. Bazer Teresa A. Davis Sung Woo Kim Peng Li J. Marc Rhoads M. Carey Satterfield Stephen B. Smith Thomas E. Spencer Yulong Yin | 2009 | Amino Acids2009，，1： | 1 |
| 20 | Chromatin immunoprecipitation: a tool for studying histone acetylation and transcription factor binding 显示文摘 | Spencer VA Sun JM Li L | 2003 | Methods2003，31，1： | 1 |
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