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| 1 | Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists显示文摘Currently, pharmaceutical preparations are serious contributors to liver disease; hepatotoxicity ranking as the most frequent cause for acute liver failure and post-commercialization regulatory decisions. The diagnosis of hepatotoxicity remains a difficult task because of the lack of reliable markers for use in general clinical practice. To incriminate any given drug in an episode of liver dysfunction is a step-by-step process that requires a high degree of suspicion, compatible chronology, awareness of the drug’s hepatotoxic potential, the exclusion of alternative causes of liver damage and the ability to detect the presence of subtle data that favors a toxic etiology. This process is time-consuming and the final result is frequently inaccurate. Diagnostic algorithms may add consistency to the diagnostic process by translating the suspicion into a quantitative score. Such scales are useful since they provide a framework that emphasizes the features that merit attention in cases of suspected hepatic adverse reaction as well. Current efforts in collecting bona fide cases of drug-induced hepatotoxicity will make refinements of existing scales feasible. It is now relatively easy to accommodate relevant data within the scoring system and to delete low-impact items. Efforts should also be directed toward the development of an abridged instrument for use in evaluating suspected drug-induced hepatotoxicity at the very beginning of the diagnosis and treatment process when clinical decisions need to be made. The instrument chosen would enable a confident diagnosis to be made on admission of the patient and treatment to be fine-tuned as further information is collected. | Raúl J Andrade Mercedes Robles Alejandra Fernández-Castaer Susana López-Ortega M Carmen López-Vega M Isabel Lucena | 2007 | World Journal of Gastroenterology2007,13,3: | 18 |
| 2 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999,,3: | 5 |
| 3 | Current role and future perspectives of cardiac rehabilitation in coronary heart disease显示文摘Ischaemic heart disease(IHD)is a major cause of morbidity and mortality worldwide.While there have been major advances in this field,these patients are still a higher risk subgroup.As such,strategies to mitigate risk and tailor secondary prevention measures are of the utmost relevance.Cardiac rehabilitation(CR),encompassing several domains including exercise training,cardiovascular risk factor optimization,nutritional and psychological assessments,as well as other ancillary interventions has shown to be one of the pillars in the contemporary management of patients with IHD.Indeed,CR is associated with several benefits in this population,ranging from functional capacity to improvements in outcomes.Whilst this,there are still several issues concerning the optimal application of CR which are still not fully ascertained,such as lack of referral and completion,as well as questions related to programme design(particularly among patients with multiple comorbidities).In this review,we aim at presenting a pragmatic overview on the current role of CR in the management of individuals with IHD,while also discussing some of the caveats in the current data,as well as future concepts which could help improve the uptake and personalization of this pivotal time-tested intervention. | Eduardo M Vilela Ricardo Ladeiras-Lopes Ana Joao Joana Braga Susana Torres Sofia Viamonte José Ribeiro Madalena Teixeira José P Nunes Ricardo Fontes-Carvalho | 2021 | World Journal of Cardiology2021,13,12: | 5 |
| 4 | Land cover changes and fragmentation in mountain neotropical ecosystems of Oaxaca, Mexico under community forest management显示文摘Changes in land cover have a direct impact on forest ecosystem goods and services. In this study, changes in land cover in Sierra de Juarez–Oaxaca ecosystems were estimated using a consistent processing of Landsat images and OBIA methodology. Additionally, landscape analyses using FRAGSTAT were conducted. In 2014, Sierra de Juarez–Oaxaca was covered by approximately 84% of forests, mainly pine-oak and cloud forests. After extensive deforestation until 2001, this trend was reversed and the forest cover surface area in 2014 was slightly higher than in 1979. The comparison of the landscape structure of the forested and agricultural lands suggests an increase in habitat heterogeneity. However, interspersion and juxtaposition indices, showing the patch shape by patch area and perimeter, were similar throughout the study period(1979–2014). Social and economic drivers can explain this situation: namely, community organization, forest enterprises, payment for ecosystem services programs, and changes of agricultural activity. Communities in the Sierra of Oaxaca have reforested degraded lands, created community forest enterprises, and preserved the forest under conservation schemes like those proposed by the Mexican payment for ecosystem services programs. However, their sustainable management faces internal challenges and has become highly dependent on political and institutional decisions beyond their control. | Rafael M~a Navarro Cerrillo Dennis J.Esteves Vieira Susana Ochoa-Gaona Bernardus H.J.de Jong M~a del Mar Delgado Serrano | 2019 | Journal of Forestry Research2019,30,1: | 4 |
| 5 | National natural capital accounting with the ecological footprint concept显示文摘 | Mathis Wackernagel Larry Onisto Patricia Bello Alejandro Callejas Linares Ina Susana López Falfán Jesus Méndez Garc??a Ana Isabel Suárez Guerrero Ma Guadalupe Suárez Guerrero | 1999 | Ecological Economics1999,,3: | 3 |
| 6 | Interaction of different polyphenols with Bovine Serum Albumin (BSA) and Human Salivary r-Amylase (HSA) by fluorescence quenching显示文摘 | SUSANA S NUNO M VICTOR DE F | 2007 | J Agric Food Chem2007,55,: | 1 |
| 7 | Power ENO methods: a fifth-order accurate weighted power ENO method显示文摘 | Susana S Antonio M | 2004 | Journal of Computational Physics2004,194,: | 1 |
| 8 | Zeolite as efficient catalysts for key transformations in carbohydrate chemistry 显示文摘 | Xavier Nuno M Lucas Susana D Rauter Amelia P | 2009 | Journal of Molecular Catalysis A: Chemical2009,305,12: | 1 |
| 9 | Modeling res- piration rate of shredded Galena kale for development of modi- fied atmosphere packaging 显示文摘 | Susana C F Fernanda A R O Jesus M F | 2002 | Journal of Food Engineering2002,54,4: | 1 |
| 10 | Hydrolysis-induced aqueous gelcasting for near-net shapeforming of ZTA ceramic composites显示文摘 | Ganesh Ibram Olhero Susana M Torres Paula M C | 2009 | Journal of theEuropean Ceramic Society2009,29,8: | 1 |
| 11 | Raman microspectroscopic studies of amber resins with insect inclusions显示文摘 | Howell G M Edwards Dennis W Farwell Susana E Jorge Villar | 2007 | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2007,68,4: | 1 |
| 12 | Choice modelling approaches: a superior alternative for environmental evaluation显示文摘 | HANLEYN SUSANA M ROBERT W | 2001 | Journal of economical surveys2001,15,3: | 1 |
| 13 | Composition and Antimicrobial Activity of the Essential Oils from Invasive Species of the Azores,Hedychium gardnerianum and Pittosporum undulatum显示文摘 | Jorge R M Lurdes B C Susana C M | 2003 | Phytochemistry2003,64,: | 1 |
| 14 | Chemical characteristics and mineral composition of quinoa by near‐infrared spectroscopy显示文摘 | M Inmaculada González Martín Guillermo Wells Moncada Susana Fischer Olga Escuredo | 2014 | Food Agric2014,,5: | 1 |
| 15 | Growth and proteolytic activity of hairy roots from Centaurea calcitrapa-effect of nitrogen and sucrose显示文摘 | Pedro M L L Susana de C Tiago M M | 2002 | Enzyme and Microbial Technology2002,31,3: | 1 |
| 16 | Mechanical improvement of concrete by irradiated polypropylene fibers 显示文摘 | GONZALO M B ENRIQUE V S SUSANA H L | 2005 | Polymer Engineering and Science2005,45,10: | 1 |
| 17 | Agile and resilient approaches to supply chain management: influence on performance and competitiveness 显示文摘 | CARVALHO H SUSANA G A VIRGILIO C M | 2012 | Logistics Research2012,4,12: | 1 |
| 18 | Effects of intravenous albumin in patients with cirrhosis and episodic hepatic encephalopathy: A randomized double-blind study显示文摘 | Macarena Simón-Talero Rita García-Martínez Maria Torrens Salvador Augustin Susana Gómez Gustavo Pereira Mónica Guevara Pere Ginés Germán Soriano Eva Román Jordi Sánchez-Delgado Roser Ferrer Juan C. Nieto Pilar Sunyé Inma Fuentes Rafael Esteban Juan Córdob | 2013 | Journal of Hepatology2013,,6: | 1 |
| 19 | Differential cellular localization of estrogen receptor in uterine and mammary cells显示文摘 | Paula M Susana Z Ricardo B | 2001 | Mol Cell Endocrinol2001,181,: | 1 |
| 20 | Ocular Aberrations before and after Myopic Corneal Refractive Surgery:LASIK-Induced Changes Measured with Laser Ray Tracing显示文摘 | ESTBER M B JESUS M L SUSANA M | 2001 | Investigative Ophthalmology & Visual Science2001,42,6: | 1 |