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5篇 您的检索式:作者名="Saguna"
    题名 作者 年代 出处 被引量
1JC virus induces altered patterns of cellular gene expression: Interferon-inducible genes as major transcriptional targets显示文摘Saguna Verma Katja Ziegler Praveen Ananthula Juliene K.G. Co Richard J. Frisque Richard Yanagihara Vivek R. Nerurkar 2005Virology2005,,2:1
2Ref(2 ) P, the Drosophila melanogaster homologue of mammalian p62,is required for the for- marion of protein aggregates in adult brain 显示文摘Nezis IP Simonsen A Saguna AP 2008J Cell Biol2008,180,6:1
3Triggering receptor expressed on myeloid cells-1 ( TREM-1 ) : a new player in antiviral immunity? 显示文摘Kelsey Roe S6bastien Gibot Saguna Verma 2014Front Microbiol2014,5,26:1
4econdary Acute Lympho-blastic Leukemia after Hodgkin 's Lymphoma or a CoincidentalAssociation of Two Hematological Malignancies 显示文摘STevet M Oragan C Saguna C 2013Maedica(Buchar)2013,8,4:1
5Single institution experience with the Ladd's procedure in patients with heterotaxy and stage Ⅰ palliated single-ventricle显示文摘AIM:To investigate and describe our current institutional management protocol for single-ventricle patients who must undergo a Ladd's procedure.METHODS:We retrospectively reviewed the charts of all patients from January 2005 to March 2014 who were diagnosed with heterotaxy syndrome and an associated intestinal rotation anomaly who carried a cardiac diagnosis of functional single ventricle and were status post stage I palliation.A total of 8 patients with a history of stage I single-ventricle palliation underwent Ladd's procedure during this time period.We reviewed each patients chart to determine if significant intraoperative or post-operative morbidity or mortality occurred.We also described our protocolized management of these patients in the cardiac intensive care unit,which included pre-operative labs,echocardiography,milrinone infusion,as well as protocolized fluid administration and anticoagulation regimines.We also reviewed the literature to determine the reported morbidity and mortality associated with the Ladd's procedure in this particular cardiac physiology and if other institutions have reported protocolized care of these patients.RESULTS:A total of 8 patients were identified to have heterotaxy with an intestinal rotation anomaly and single-ventricle heart disease that was status post single ventricle palliation.Six of these patients were palliated with a Blaylock-Taussig shunt,one of whom underwent a Norwood procedure.The two other patients were palliated with a stent,which was placed in the ductus arteriosus.These eight patients all underwent elective Ladd's procedure at the time of gastrostomy tube placement.Per our protocol,all patients remained on aspirin prior to surgery and had no period where they were without anticoagulation.All patients remained on milrinone during and after the procedure and received fluid administration upon arrival to the cardiac intensive care unit to account for losses.All 8 patients experienced no intraoperative or post-operative complications.All patients survived to discharge.One patient presented to the emergency room two months after discharge in cardiac arrest and died due to bowel obstruction and perforation.CONCLUSION:Protocolized intensive care management may have contributed to favorable outcomes following Ladd's procedure at our institution.Kurt D Piggott Grace George Harun Fakioglu Carlos Blanco Sukumar Saguna Narasimhulu Kamal Pourmoghadam Hamish Munroe William Decampli 2016World Journal of Clinical Pediatrics2016,5,3:0
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