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9篇 您的检索式:作者名="Salaroli"
    题名 作者 年代 出处 被引量
1Repeatability of laser in situ keratomileusis flap thickness measurement by Fourier-domain optical coherence tomography显示文摘Salaroli CHR Li Y Zhang X 0,,:1
2XAV939-mediated ARTD activity inhibition in human MB cell lines显示文摘RENNA C SALAROLI R COCCHI C 2015PLoS One2015,10,01:1
3Re- vised IPSS (IPSS-R) stratification and outcome of MDS patients treated with azacitidine显示文摘BRECCIA M SALAROLI A LOGLISCI G 2013Ann Hema- tol2013,92,:1
4Systematic review of dasatinib in chronic myeloid leukemia 显示文摘BRECCIA M SALAROLI A MOLICA 2013OncoTargets Ther2013,6,5:1
5Systematic review of dasatinib in chronic myeloid leukemia 显示文摘Breccia M Salaroli A Molica 2013OncoTargets Ther2013,6,5:1
6Lithium induces mortality in medulloblastoma cell lines显示文摘Ronchi A Salaroli R Rivetd S 2010Int J Oncol2010,37,3:1
7Architectural analysis of clear corneal incision techniques in cataract surgery using Fourier-Domain OCT显示文摘Teixeira A Salaroli C Filho FR 2012Ophthalmic Surg Lasers Imaging2012,43,:1
8Deferasirox treatment interruption in a transfurion-requiring myelodysplastic patient led to loss of erythroid response显示文摘Breccia M Loglisci G Salaroli A 0,,01:1
9Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia显示文摘BACKGROUND Mesenchymal stromal cell(MSC)-based therapy is currently under study to treat inflammatory bowel diseases.MSC bioactive products could represent a valid alternative to overcome issues associated with systemic whole-cell therapies.However,MSC anti-inflammatory mechanisms differ between rodents and humans,impairing the reliability of preclinical models.AIM To evaluate the effect of conditioned medium(CM)derived from porcine vascular wall MSCs(pVW-MSCs)on survival and differentiation of porcine and guinea pig enteric ganglia exposed to lipopolysaccharide(LPS).METHODS Primary cultures of enteric ganglia were obtained by mechanic and enzymatic digestion of ileum resections from guinea pigs(Cavia porcellus)(GPEG)and pigs(Suus scrofa)(PEG).pVW-MSCs were derived by enzymatic digestion from vascular wall resections of porcine aorta and tested by immunoflowcytometry for MSC immune profile.Enteric ganglia were treated with increasing concentrations of LPS,CM derived by pVW-MSCs or a combination of CM and LPS 1μg/mL.Cell count and morphometric analysis of HuD positive neurons and glial fibrillary acidic protein positive glial cells were performed by immunofluorecent staining of cultured ganglia.RESULTS PEG showed a higher number of neurons compared to GPEG.Overall,CM exerted a protective role on LPS-treated enteric ganglia.CM in combination with LPS increased the number of glial cells per ganglion in both cultures evoking glial cells differentiation in porcine cultures.CONCLUSION These findings suggest an immunomodulating activity of pVW-MSCs mediators on the enteric nervous system in inflammatory conditions.Giovanni Dothel Chiara Bernardini Augusta Zannoni Maria Rosaria Spirito Roberta Salaroli Maria Laura Bacci Monica Forni Fabrizio De Ponti 2019World Journal of Gastroenterology2019,25,33:0
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