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| 1 | Intensivist-based deep sedation using propofol for pediatric outpatient flexible bronchoscopy显示文摘AIM To evaluate the safety and efficacy of sedating pediatric patients for outpatient flexible bronchoscopy.METHODS A retrospective chart review was conducted for all children, age 17 years or under who underwent flexible bronchoscopy under deep sedation in an outpatient hospital-based setting. Two sedation regimens were used; propofol only or ketamine prior to propofol. Patients were divided into three age groups; infants(less than 12 mo), toddlers(1-3 years) and children(4-17 years). Demographics, indication for bronchoscopy, sedative dosing, sedation and recovery time and adverse events were reviewed.RESULTS Of the total 458 bronchoscopies performed, propofol only regimen was used in 337(74%) while propofol and ketamine was used in 121(26%). About 99% of the procedures were successfully completed. Children in the propofol + ketamine group tend to be youngerand have lower weight compared to the propofol only group. Adverse events including transient hypoxemia and hypotension occurred in 8% and 24% respectively. Median procedure time was 10 min while the median discharge time was 35 min. There were no differences in the indication of the procedure, propofol dose, procedure or recovery time in either sedative regimen. When compared to other age groups, infants had a higher incidence of hypoxemia.CONCLUSION Children can be effectively sedated for outpatient flexible bronchoscopy with high rate of success. This procedure should be performed under vigilance of highly trained providers. | Kamal Abulebda Samer Abu-Sultaneh Sheikh Sohail Ahmed Elizabeth A S Moser Renee C McKinney Riad Lutfi | 2017 | World Journal of Critical Care Medicine2017，6，4： | 8 |
| 2 | A computer program for monitoring and controlling ultrasonic anemome- ters for aerodynamic measurements in animal buildings 显示文摘 | Samer M Loebsin C Bobrutzki K Von | 2011 | Computers and Electronics in Agriculture2011，79，： | 1 |
| 3 | Pharmacogenetics of analgesics: toward the individualization of prescription显示文摘 | Rollason V Samer C Piguet V | 2008 | Pharmacogenomics2008，9，7： | 1 |
| 4 | Moving towards dose individualization of tyrosine kinase inhibitors 显示文摘 | KLUMPEN H J SAMER C F MATHIJSSEN R H | 2011 | Cancer Treat Rev2011，37，4： | 1 |
| 5 | Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers显示文摘 | Ancrenaz V Deglon J Samer C | 2013 | Basic Clin Pharmacol Toxicol2013，112，2： | 1 |
| 6 | 显示文摘 | Samer C J Joseph Schork F | 1999 | Ind Eng Chem Res1999，38，： | 1 |
| 7 | Applications of CYP450 testing in the clinical setting显示文摘 | Samer C F lng Lorenzini K Rollason V | 2013 | Mol Diagn Ther2013，17，3： | 1 |
| 8 | Increased concentrations of tirofiban in blood and their correlation with inhibition of platelet aggregation after greater bolus doses of tirofiban显示文摘 | David J Schneider Howard C Herrmann Nasser Lakkis Frank Aguirre Man-Wai Lo Kuo-Chang Yin Atul Aggarwal Samer S Kabbani Peter M DiBattiste | 2003 | The American Journal of Cardiology2003，，3： | 1 |
| 9 | The compatibility of Hly factor, a transmissible element that controls alpha-hemolysin production in Escherichia coli显示文摘 | Monti-Bragadin C Samer L Rottini G | 1975 | J Gen Microbiol1975，86，2： | 1 |
| 10 | Epstein-Barr-virus-induced interstitial lung dis-ease显示文摘 | KAMEL M LALAINE C SAMER S | 2005 | Current Opinion in Pulmonary Medicine2005，11，： | 1 |
| 11 | The role of high shear in continuous miniemulsion polymerization显示文摘 | Samer C J Schork F J | 1999 | Ind Eng Chem Res1999，38，： | 1 |
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