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93篇 您的检索式:作者名="Saraya"
    题名 作者 年代 出处 被引量
1Plasma cathepsin L:A prognostic marker for pancreatic cancer显示文摘AIM:To assess the prognostic significance of cathepsin L,a cysteine protease that degrades the peri-tumoral tissue,in patients with pancreatic cancer.METHODS:Plasma samples from 127 pancreatic cancer patients were analyzed for cathepsin L levels by ELISA.Out of these patients,25 underwent surgeryand their paraffin-embedded tissue was analyzed for cathepsin L expression by immunohistochemistry.Survival of patients and clinicopathological parameters was correlated with cathepsin L expression in plasma and tissue using appropriate statistical analysis.RESULTS:The mean(±SD)cathepsin L in plasma samples of pancreatic cancer patients was 5.98±2.5ng/m L that was significantly higher compared to the levels in healthy controls(3.83±0.45)or chronic pancreatitis patients(3.97±1.06).Using ROC curve,a cut-off level of 5.0 ng/m L was decided for survival analysis.Elevated plasma levels of cathepsin L were found to be associated with poor prognosis(P=0.01)in multivariate analysis.The plasma levels of the protease decreased after surgery.Though no significant correlation was seen between plasma and tissue expression of this protease,a trend did emerge that high cathepsin L expression in tissue correlated with its high levels in plasma.CONCLUSION:Cathepsin L levels in plasma of pancreatic cancer patients may be used as a potential prognostic marker for the disease.Nidhi Singh Prasenjit Das Surabhi Gupta Vikas Sachdev Siddhartha Srivasatava Siddhartha Datta Gupta Ravindra Mohan Pandey Peush Sahni Shyam S Chauhan Anoop Saraya 2014World Journal of Gastroenterology2014,20,46:2
2Prognostic Significance of Extracellular Matrix Degrading Enzymes—Cathepsin L and Matrix Metalloproteases-2 [MMP-2] in Human Pancreatic Cancer显示文摘Nidhi Singh Prasenjit Das Siddhartha Datta Gupta Peush Sahni R. M. Pandey Surabhi Gupta Shyam S. Chauhan Anoop Saraya 2013Cancer Investigation2013,,7:2
3A Randomized Controlled Trial of Antioxidant Supplementation for Pain Relief in Patients With Chronic Pancreatitis显示文摘Payal Bhardwaj Pramod Kumar Garg Subir Kumar Maulik Anoop Saraya Rakesh Kumar Tandon Subrat Kumar Acharya 2009Gastroenterology2009,,1:2
4Early Enteral Nutrition in Severe Acute Pancreatitis: A Prospective Randomized Controlled Trial Comparing Nasojejunal and Nasogastric Routes显示文摘Ajay Kumar Namrata Singh Shyam Prakash Anoop Saraya Yogendra Kumar Joshi 2006Journal of Clinical Gastroenterology2006,,5:2
5A pancreatography study of chronic caIcific pancreatitis of the tropics显示文摘Saraya A Acharya SK Vashist S 2002Trop Gastroenterol2002,23,4:1
6Clinical, radiological and functional assessment of pulmonary status in patients with achalasia cardia before and after treatment显示文摘Rajinder Parshad Sudheer Kumar Devana Karthik Panchanatheeswaran Anoop Saraya Govind K. Makharia Surendra Kumar Sharma Ashu Seith Bhalla 2012European Journal of Cardio-Thoracic Surgery2012,,5:1
7High-resolu- tion CT findings of patients with pulmonary nocardiosis 显示文摘Naoki Tsujimoto Takeshi Saraya Ken Kikuchi 2012J Tho- rac Dis2012,4,6:1
8Pathological Evidence of Rhabdomyolysis-induced Acute Tubulointerstitial Nephritis Accompanying Legionella pneumophila Pneumonia显示文摘Shimura C Saraya T Wada H 2008Clin Pathol J Clin Pathol2008,61,9:1
9The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side popu- lation cells in hepatocellular carcinoma显示文摘Chiba T Miyagi S Saraya A 2008Cancer Res2008,68,19:1
10Effects of fluoroquinolones on insulin secretion and β-cell ATP-sensitive K + channels显示文摘Atsunori Saraya Masaaki Yokokura Tohru Gonoi Susumu Seino 2004European Journal of Pharmacology2004,,1:1
11The Polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma显示文摘Chiba T Miyagi S Saraya A 2008Cancer Res2008,68,:1
12Depletion of Sf3bl impairs proliferative capacity of hematopoietic stem cells but is not sufficient to induce myelodysplasia 显示文摘Wang C Sashida G Saraya A 2014Blood2014,123,21:1
13High-resolution CT findings of patients with pulmonary nocardiosis显示文摘Tsujimoto N Saraya T Kikuchi K 2012J Thorac Dis2012,4,6:1
14Effect of fluoro- qninolones on insulin and beta-cell ATP-sensitive K^+ channels 显示文摘Saraya A Yokokura M Gonoi T 2004Eur J Pharmacol2004,497,1:1
15The polycomb gene product BMI1 contributes to the maintenance of tumor - initiating side population ceils in hepatocellular carcinoma 显示文摘Chiba T Miyagi S Saraya A 2008Cancer Res2008,68,19:1
16Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘 Yokokura M Gonoi T 2004European Journal of Pharmacology2004,497,1:1
17Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘Saraya A Yokokura M Gonoi T 2004Eur J Pharmacol2004,497,:1
18The role of procalci- tonin as a guide for the diagnosis,proguosis,and decision of an- tibiotic therapy for lower respiratory tract infections显示文摘E1-Azeem AA Hamdy G Saraya M 2013Egypt J Chest Dis Tuberc2013,62,:1
19A Randomized Controlled Trial of Antioxidant Supplementation for Pain Relief in Patients With Chronic Pancreatitis显示文摘Payal Bhardwaj Pramod Kumar Garg Subir Kumar Maulik Anoop Saraya Rakesh Kumar Tandon Subrat Kumar Acharya 2009Gastroenterology2009,,1:1
20Effects of fluoroquinolones on insulin secretion and beta-cell ATP-sensitive K+ channels显示文摘 Yokokura M Gonoi T Sdno S 2004Eur J Pharmacol2004,497,:1
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