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| 1 | Preeclampsia in women with chronic kidney disease显示文摘 | Giuseppe Maria Maruotti Laura Sarno Raffaele Napolitano Laura Letizia Mazzarelli Filomena Quaglia Angela Capone Alfredo Capuano Pasquale Martinelli | 2012 | Journal of Maternal-Fetal and Neonatal Medicine2012，，8： | 1 |
| 2 | Influence of the polymer structure and nanotube concentration on the conductivity and rheological properties of polyethylene/ CNTcomposites 显示文摘 | Valentino Olga Sarno Maria Rainone Nicola G | 2008 | Physica E2008，40，7： | 1 |
| 3 | Boceprevir or telaprevir in hepatitis C virus chronic infection:The Italian real life experience显示文摘AIM: To check the safety and efficacy of boceprevir/telaprevir with peginterferon/ribavirin for hepatitis C virus(HCV) genotype 1 in the real-world settings. METHODS: This study was a non-randomized, observational, prospective, multicenter. This study involved 47 centers in Italy. A database was prepared for the homogenous collection of the data, was used by all of the centers for data collection, and was updated continuously. All of the patients enrolled in this study were older than 18 years of age and were diagnosed with chronic infection due to HCV genotype 1. The HCV RNA testing was performed using COBAS-Taq Man2.0(Roche, LLQ 25 IU/m L). RESULTS: All consecutively treated patients were included. Forty-seven centers enrolled 834 patients as follows: Male 64%; median age 57(range 18-78), of whom 18.3% were over 65; mean body mass index 25.6(range 16-39); genotype 1b(79.4%); diagnosis of cirrhosis(38.2%); and fibrosis F3/4(71.2%). The following drugs were used: Telaprevir(66.2%) and PEG-IFN-alpha2a(67.6%). Patients were na?ve(24.4%), relapsers(30.5%), partial responders(14.8%) and null responders(30.3%). Overall, adverse events(AEs) occurred in 617 patients(73.9%) during the treatment. Anemia was the most frequent AE(52.9% of cases), especially in cirrhotic. The therapy was stopped for 14.6% of the patients because of adverse events or virological failure(15%). Sustained virological response was achieved in 62.7% of the cases, but was 43.8% in cirrhotic patients over 65 years of age. CONCLUSION: In everyday practice, triple therapy is safe but has moderate efficacy, especially for patients over 65 years of age, with advanced fibrosis, nonresponders to peginterferon + ribavirin. | Antonio Ascione Luigi Elio Adinolfi Pietro Amoroso Angelo Andriulli Orlando Armignacco Tiziana Ascione Sergio Babudieri Giorgio Barbarini Michele Brogna Francesco Cesario Vincenzo Citro Ernesto Claar Raffaele Cozzolongo Giuseppe D’Adamo Emilio D’Amico Pellegrino Dattolo Massimo De Luca Vincenzo De Maria Massimo De Siena Giuseppe De Vita Antonio Di Giacomo Rosanna De Marco Giorgio De Stefano Giulio De Stefano Sebastiano Di Salvo Raffaele Di Sarno Nunzia Farella Laura Felicioni Basilio Fimiani Luca Fontanella Giuseppe Foti Caterina Furlan Francesca Giancotti Giancarlo Giolitto Tiziana Gravina Barbara Guerrera Roberto Gulminetti Angelo Iacobellis Michele Imparato Angelo Iodice Vincenzo Iovinella Antonio Izzi Alfonso Liberti Pietro Leo Gennaro Lettieri Ileana Luppino Aldo Marrone Ettore Mazzoni Vincenzo Messina Roberto Monarca Vincenzo Narciso Lorenzo Nosotti Adriano Maria Pellicelli Alessandro Perrella Guido Piai Antonio Picardi Paola Pierri Grazia Pietromatera Francesco Resta Luca Rinaldi Mario Romano Angelo Rossini Maurizio Russello Grazia Russo Rodolfo Sacco Vincenzo Sangiovanni Antonio Schiano Antonio Sciambra Gaetano Scifo Filomena Simeone Annarita Sullo Pierluigi Tarquini Paolo Tundo Alfredo Vallone | 2016 | World Journal of Hepatology2016，8，22： | 1 |
| 4 | Validation of ninhydrin quantitative method for cephalexin generic tablets 显示文摘 | RAUL DELFINO M MARIA MONZON C DEL CARMEN TERESA SARNO M | 2013 | Current Pharmaceutical Analysis2013，9，1： | 1 |
| 5 | Lamb-dip saturated-absorption cavity ring-down rovibrational molecular spectroscopy in the near-infrared显示文摘The high-detection-sensitivity saturated-absorption cavity ring-down(SCAR)technique is extended to Lambdip spectroscopy of rovibrational molecular transitions in the near-infrared region.Frequency-comb-referenced sub-Doppler saturation measurements,performed on the acetylene(ν_(1)+ν_(3)+ν_(4)←ν_(4))R(14)e line at6562 cm^(-1),are analyzed by a SCAR global line profile fitting routine,based on a specially developed theoretical model.Compared to a conventional cavity ring-down evaluation,our approach yields dip profiles with a linewidth freed from saturation broadening effects,reduced by 40%,and a signal-to-noise ratio increased by 90%.Ultimately,an overall(statistical and systematic)fractional uncertainty as low as 7×10^(-12)is achieved for the absolute line-center frequency.At the same time,our method is also able to accurately infer the linear(nonsaturated)behavior of the gas absorption,providing Lamb-dip-based line strength measurements with a relative uncertainty of 0.5%. | ROBERTO AIELLO VALENTINA DI SARNO MARIA GIULIA DELLI SANTI MAURIZIO DE ROSA IOLANDA RICCIARDI GIOVANNI GIUSFREDI PAOLO DE NATALE LUIGI SANTAMARIA PASQUALE MADDALONI | 2022 | Photonics Research2022，10，8： | 0 |
| 6 | CNTs tuning and vertical alignment in anodic aluminium oxide membrane显示文摘Anodic aluminium oxide (AAOM) membranes were used for template growth of carbon nanotubes (CNT) inside their pores by chemical vapour deposition (CVD) of different hydrocarbons, in the absence of transition metal catalyst. A composite material, containing one nanotube for each channel, having the same length as the membrane thickness and the external diameter close to the diameter of the membrane holes, was obtained. Yield, selectivity, and quality of CNTs in terms of diameter (up to very thin CNT), carbon order, length, arrangement (i.e. number of tubes for each channel), purity, that are critical requisites for several applications were optimized by investigating the effect of changing the hydrocarbon feedstock gas, also in the presence of hydrogen. The samples produced using methane as a feedstock have a well ordered structure. The role of the alumina channels surface during the CNT growth has been investigated and its catalytic activity has been proved for the first time. | Maria Sarno Diana Sannino Caterina Leone Paolo Ciambelli | 2012 | Journal of Natural Gas Chemistry2012，21，6： | 0 |
| 7 | Protein kinase CK2: a potential therapeutic target for diverse human diseases显示文摘CK2 is a constitutively active Ser/Thr protein kinase,which phosphorylates hundreds of substrates,controls several signaling pathways,and is implicated in a plethora of human diseases.Its best documented role is in cancer,where it regulates practically all malignant hallmarks.Other well-known functions of CK2 are in human infections;in particular,several viruses exploit host cell CK2 for their life cycle.Very recently,also SARS-CoV-2,the virus responsible for the COVID-19 pandemic,has been found to enhance CK2 activity and to induce the phosphorylation of several CK2 substrates(either viral and host proteins).CK2 is also considered an emerging target for neurological diseases,inflammation and autoimmune disorders,diverse ophthalmic pathologies,diabetes,and obesity.In addition,CK2 activity has been associated with cardiovascular diseases,as cardiac ischemia-reperfusion injury,atherosclerosis,and cardiac hypertrophy.The hypothesis of considering CK2 inhibition for cystic fibrosis therapies has been also entertained for many years.Moreover,psychiatric disorders and syndromes due to CK2 mutations have been recently identified.On these bases,CK2 is emerging as an increasingly attractive target in various fields of human medicine,with the advantage that several very specific and effective inhibitors are already available.Here,we review the literature on CK2 implication in different human pathologies and evaluate its potential as a pharmacological target in the light of the most recent findings. | Christian Borgo Claudio D'Amore Stefania Sarno Mauro Salvi Maria Ruzzene | 2021 | Signal Transduction and Targeted Therapy2021，6，6： | 0 |
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