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| 1 | Role of hepatectomy for recurrent or initially unresectable hepatocellular carcinoma显示文摘As a result of donor shortage and high postoperative morbidity and mortality after liver transplantation,hepatectomy is the most widely applicable and reliable option for curative treatment of hepatocellular carcinoma(HCC).Because intrahepatic tumor recurrence is frequent after loco-regional therapy,repeated treatments are advocated provided background liver function is maintained.Among treatments including local ablation and transarterial chemoembolization,hepatectomy provides the best long-term outcomes,but studies comparing hepatectomy with other nonsurgical treatments require careful review for selection bias.In patients with initially unresectable HCC,transarterial chemo-or radio-embolization,and/or systemic chemotherapy can down-stage the tumor and conversion to resectable HCC is achieved in approximately 20%of patients.However,complete response is rare,and salvage hepatectomy is essential to help prolong patients’survival.To counter the short recurrence-free survival,excellent overall survival is obtained by combining and repeating different treatments.It is important to recognize hepatectomy as a complement,rather than a contraindication,to other nonsurgical treatments in a mul-tidisciplinary approach for patients with HCC,including recurrent or unresectable tumors. | Yoji Kishi Kazuaki Shimada Satoshi Nara Minoru Esaki Tomoo Kosuge | 2014 | World Journal of Hepatology2014，6，12： | 5 |
| 2 | Efficacy of a Hepatectomy and a Tumor Thrombectomy for Hepatocellular Carcinoma with Tumor Thrombus Extending to the Main Portal Vein显示文摘 | Daisuke Ban Kazuaki Shimada Yusuke Yamamoto Satoshi Nara Minoru Esaki Yoshihiro Sakamoto Tomoo Kosuge | 2009 | Journal of Gastrointestinal Surgery2009，，11： | 4 |
| 3 | Liver atrophy after percutaneous transhepatic portal embolization occurs in two histological phases: Hepatocellular atrophy followed by apoptosis显示文摘AIM To clarify the histological changes associated with liver atrophy after percutaneous transhepatic portalembolization(PTPE) in pigs and humans. METHODS As a preliminary study, we performed pathological examinations of liver specimens from five pigs that had undergone PTPE in a time-dependent model of liver atrophy. In specimens from embolized lobes(EMB) and nonembolized lobes(controls), we measured the portal vein to central vein distance(PV-CV), the area and number of hepatocytes per lobule, and apoptotic activity using the terminal deoxynucleotidyl transferase dU TP nickend labeling assay. Immunohistochemical reactivities were evaluated for light chain 3(LC3) and lysosomal-associated membrane protein 2(LAMP2) as autophagy markers and for glutamine synthetase and cytochrome P450 2 E1(CYP2 E1) as metabolic zonation markers. Samples from ten human livers taken 20-36 d after PTPE were similarly examined. RESULTS PV-CVs and lobule areas did not differ between EMB and controls at day 0, but were lower in EMB than in controls at weeks 2, 4, and 6(P ≤ 0.001). Hepatocyte numbers were not significantly reduced in EMB at day 0 and week 2 but were reduced at weeks 4 and 6(P ≤ 0.05). Apoptotic activity was higher in EMB than in controls at day 0 and week 4. LC3 and LAMP2 staining peaked in EMB at week 2, with no significant difference between EMB and controls at weeks 4 and 6. Glutamine synthetase and CYP2 E1 zonation in EMB at weeks 2, 4, and 6 were narrower than those in controls. Human results were consistent with those of porcine specimens. CONCLUSION The mechanism of liver atrophy after PTPE has two histological phases: Hepatocellular atrophy is likely caused by autophagy in the first 2 wk and apoptosis thereafter. | Yasuhito Iwao Hidenori Ojima Tatsushi Kobayashi Yoji Kishi Satoshi Nara Minoru Esaki Kazuaki Shimada Nobuyoshi Hiraoka Minoru Tanabe Yae Kanai | 2017 | World Journal of Hepatology2017，9，32： | 1 |
| 4 | Is celiac axis resection justified for T4 pancreatic body cancer?显示文摘 | Yusuke Yamamoto Yoshihiro Sakamoto Daisuke Ban Kazuaki Shimada Minoru Esaki Satoshi Nara Tomoo Kosuge | 2012 | Surgery2012，，1： | 1 |
| 5 | Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement显示文摘 | Kazuaki Shimada Tsuyoshi Sano Satoshi Nara Minoru Esaki Yoshihiro Sakamoto Tomoo Kosuge Hidenori Ojima | 2009 | Surgery2009，，4： | 1 |
| 6 | A Closed Form Formula for Magnetic Dipole Localization by Measurement of Its Magnetic Field and Spatial Gradients显示文摘 | Takaaki Nara Satoshi Suzuki Shigeru Ando | 2006 | IEEE Transactions on Magnetics2006，42，10： | 1 |
| 7 | A closed form formula for magnetic dipole localization by measurement of its magnetic field and spatial gradients显示文摘 | TAKAAKI NARA SATOSHI SUZUKI SHIGERU ANDO | 2006 | IEEE Transactions on Magnetics2006，42，10： | 1 |
| 8 | Therapeutic value of lymph node dissection during hepatectomy in patients with intrahepatic cholangiocellular carcinoma with negative lymph node involvement显示文摘 | Kazuaki Shimada Tsuyoshi Sano Satoshi Nara Minoru Esaki Yoshihiro Sakamoto Tomoo Kosuge Hidenori Ojima | 2009 | Surgery2009，，4： | 1 |
| 9 | A closedform formula for magnetic dipole localization by measurement of its magnetic field and spatial gradient显示文摘 | Takaaki Nara Satoshi Suzuki Shigeru Ando | | 0，，10： | 1 |
| 10 | Surgical Management of Infrahilar/Suprapancreatic Cholangiocarcinoma: an Analysis of the Surgical Procedures, Surgical Margins, and Survivals of 77 Patients显示文摘 | Yoshihiro Sakamoto Kazuaki Shimada Satoshi Nara Minoru Esaki Hidenori Ojima Tsuyoshi Sano Junji Yamamoto Tomoo Kosuge | 2010 | Journal of Gastrointestinal Surgery2010，，2： | 1 |
| 11 | Roux-en-Y reconstruction using staplers during pancreaticoduodenectomy: Results of a prospective preliminary study显示文摘 | Yoshihiro Sakamoto Takahiro Kajiwara Minoru Esaki Kazuaki Shimada Satoshi Nara Tomoo Kosuge | 2009 | Surgery Today2009，，1： | 1 |
| 12 | Analysis of 5-Year Survivors After a Macroscopic Curative Pancreatectomy for Invasive Ductal Adenocarcinoma显示文摘 | Kazuaki Shimada Yoshihiro Sakamoto Satoshi Nara Minoru Esaki Tomoo Kosuge Nobuyoshi Hiraoka | 2010 | World Journal of Surgery2010，，8： | 1 |
| 13 | Multiple Primary Cancers Associated with Esophageal Carcinoma显示文摘 | Youichi Kumagai Tatsuyuki Kawano Yasuaki Nakajima Kagami Nagai Haruhiro Inoue Satoshi Nara Takehisa Iwai | 2001 | Surgery Today2001，，10： | 1 |
| 14 | Prognostic impact of marginal resection for patients with solitary hepatocellular carcinoma: Evidence from 570 hepatectomies显示文摘 | Satoshi Nara Kazuaki Shimada Yoshihiro Sakamoto Minoru Esaki Yoji Kishi Tomoo Kosuge Hidenori Ojima | 2012 | Surgery2012，，4： | 1 |
| 15 | A closed form formula for magnetic dipole localization by measurement of its magnetic field and spatial gradients显示文摘 | TAKAAKI NARA SATOSHI SUZUKI SHIGERUANDO | 2006 | IEEE Transactions on Magnetics2006，42，10： | 1 |
| 16 | A closedform formula for magnetic dipole localization by measurement of its magnetic field and spatial gradients显示文摘 | Takaaki Nara Satoshi Suzuki Shigeru Ando | 2006 | IEEE Transactions on magnetics2006，42，10： | 1 |
| 17 | A Closed-form Formula for Magnetic Dipole Localization by Measurement of Its Magnetic Field and Spatial Gradients 显示文摘 | Takaaki Nara Satoshi Suzuki Shigeru Ando | 2006 | IEEE Transactions on Magnentics2006，42，10： | 1 |
| 18 | Prognosis of patients undergoing hepatectomy for solitary hepatocellular carcinoma originating in the caudate lobe显示文摘 | Yoshihiro Sakamoto Satoshi Nara Shojiro Hata Yusuke Yamamoto Minoru Esaki Kazuaki Shimada Tomoo Kosuge | 2011 | Surgery2011，，5： | 1 |
| 19 | Multiple Primary Cancers Associated with Esophageal Carcinoma显示文摘 | Youichi Kumagai Tatsuyuki Kawano Yasuaki Nakajima Kagami Nagai Haruhiro Inoue Satoshi Nara Takehisa Iwai | 2001 | Surgery Today2001，，10： | 1 |
| 20 | Left hepatic trisectionectomy for perihilar cholangiocarcinoma with a right-sided round ligament:A case report显示文摘BACKGROUND A right-sided round ligament(RSRL)is a rare,congenital anomaly of the intrahepatic portal vein,with a reported frequency of 0.2%-1.2%.For patients with perihilar cholangiocarcinoma associated with an RSRL,an accurate understanding of the vascular and biliary anatomy is indispensable.CASE SUMMARY We report a 70-year-old male with perihilar cholangiocarcinoma associated with an RSRL.After percutaneous transhepatic embolization of the left and anterior portal branches,we conducted a left trisectionectomy of the liver with extrahepatic bile duct resection and hepaticojejunostomy.The postoperative course was uneventful,and R0 resection was achieved.When the liver volume of each section was compared between 7 patients with an RSRL and 20 patients with normal portal vein anatomy,the posterior section in RSRL patients was significantly larger than that in patients with normal portal vein anatomy(median:457 mL vs 306 mL,P=0.031).In patients with perihilar cholangiocarcinoma associated with an RSRL,left trisectionectomy has several surgical advantages:(1)The posterior branch of the portal vein often ramifies independently,and the division of the portal vein is easily conducted;(2)A relatively large amount of remnant liver can be retained;and(3)The anatomy of the posterior branch of the Glissonian pedicle is similar to that in patients with normal anatomy.CONCLUSION In patients with an RSRL and perihilar cholangiocarcinoma that does not involve the posterior section,left trisectionectomy may be a favorable choice. | Tomoyuki Ishida Satoshi Nara Keiichi Akahoshi Takeshi Takamoto Yoji Kishi Minoru Esaki Nobuyoshi Hiraoka Kazuaki Shimada | 2020 | World Journal of Gastrointestinal Surgery2020，12，2： | 0 |
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