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| 1 | Natural heme oxygenase-1 inducers in hepatobiliary function显示文摘Many physiological effects of natural antioxidants,their extracts or their major active components,have been reported in recent decades.Most of these compounds are characterized by a phenolic structure,similar to that of α-tocopherol,and present antioxidant proper-ties that have been demonstrated both in vitro and in vivo.Polyphenols may increase the capacity of en-dogenous antioxidant defences and modulate the cellu-lar redox state.Changes in the cellular redox state may have wide-ranging consequences for cellular growth and differentiation.The majority of in vitro and in vivo studies conducted so far have attributed the protective effect of bioactive polyphenols to their chemical reac-tivity toward free radicals and their capacity to prevent the oxidation of important intracellular components.However,in recent years a possible novel aspect in the mode of action of these compounds has been sug-gested; that is,the ultimate stimulation of the heme oxygenase-1 (HO-1) pathway is likely to account for the established and powerful antioxidant/anti-inflam-matory properties of these polyphenols.The products of the HO-catalyzed reaction,particularly carbon mon-oxide (CO) and biliverdin/bilirubin have been shown to exert protective effects in several organs against oxidative and other noxious stimuli.In this context,it is interesting to note that induction of HO-1 expression by means of natural compounds contributes to protec-tion against liver damage in various experimental mod-els.The focus of this review is on the significance of targeted induction of HO-1 as a potential therapeutic strategy to protect the liver against various stressors in several pathological conditions. | Giovanni Li Volti David Sacerdoti Claudia Di Giacomo Maria Luisa Barcellona Antonio Scacco Paolo Murabito Antonio Biondi Francesco Basile Diego Gazzolo Raul Abella Alessandro Frigiola Fabio Galvano | 2008 | World Journal of Gastroenterology2008，14，40： | 2 |
| 2 | A revision of the trauma score 显示文摘 | Champion HR Scacco WJ Copes WS | 1998 | J Trauma1998，29，8： | 1 |
| 3 | Influence of soil salinity on sensory characteristics and volatile aromacompounds of Nero d' Avola wine显示文摘 | Scacco A Vrezera A Lanza C M | 2010 | American Society for Enology and Viticulture2010，61，4： | 1 |
| 4 | Fast power cycling test for insulated gate bipolar transistor modules in traction application显示文摘 | M. Held P. Jacob G. Nicoletti P. Scacco M. -H. Poech | 1999 | International Journal of Electronics1999，，10： | 1 |
| 5 | Sequential serum- dependent activation of CREB and NRF - 1 leads to enhanced mitochondrial respiration through the induction of cytochrome c 显示文摘 | Herzig RP Scacco S Scarpulla RC | 2000 | J Biol Chem2000，275，13： | 1 |
| 6 | Correlation between mito-chondrial DNA 4977-bp deletion and respiratory chain enzyme activeties in aging human skeletal muscles 显示文摘 | Boffoli D Scacco S | 1994 | Biochem Biophys Res Commun1994，205，： | 1 |
| 7 | Complex I and the cAMP cascade in human physiopathology显示文摘 | Papa S Scacco S Sardanelli AM | | 0，，01： | 1 |
| 8 | Glatiramer acetate in- duces pro apoptotie mechanisms involving Bel-2, Bax and Cyt c in peripheral lymphocytes from multiple sclerosis patients显示文摘 | Ruggieri M Avolio C Scacco S | 2006 | J Neurol2006，253，2： | 1 |
| 9 | Volatile compound and sensory analysis for the character-ization of an Italian white wine from 'Inzolia' grapes显示文摘 | Verzera A Ziino M Scacco A | 2008 | Food Analytical Methods2008，1，2： | 1 |
| 10 | Dental-derived stem cells and biowaste biomaterials:What’s next in bone regenerative medicine applications显示文摘The human teeth and oral cavity harbor various populations of mesenchymal stem cells(MSCs),so called dental-derived stem cells(D-dSCs)with self-renewing and multilineage differentiation capabilities.D-dSCs properties involves a strong paracrine component resulting from the high levels of bioactive molecules they secrete in response to the local microenvironment.Altogether,this viewpoint develops a general picture of current innovative strategies to employ D-dSCs combined with biomaterials and bioactive factors for regenerative medicine purposes,and offers information regarding the available scientific data and possible applications. | MICHELE DI COSOLA STEFANIA CANTORE MARIO GIOSUÈBALZANELLI CIRO GARGIULO ISACCO KIEU CAO DIEM NGUYEN RAJIV SAINI ANNARITA MALCANGI MARGHERITA TUMEDEI MARIATERESA AMBROSINO ANTONIO MANCINI SALVATORE SCACCO RICCARDO NOCINI LUIGI SANTACROCE ANDREA BALLINI EDOARDO BRAUNER | 2022 | BIOCELL2022，46，4： | 1 |
| 11 | Complex I and the cAMP cascade in human physiopathology显示文摘 | Papa S Scacco S Sardanelli AM | | 0，，01： | 1 |
| 12 | Volatile compound and sensory analysis for the characterization of an Italian white wine from 'Inzolia' grapes显示文摘 | VERZERA A Z/INO M SCACCO A | 2008 | Food Analytical Methods2008，1，2： | 1 |
| 13 | Fast power cycling test for IGBT modules in traction application 显示文摘 | HELD M JACOB P NICOLETYI G SCACCO P | 1999 | Journal of Electronics1999，86，10： | 1 |
| 14 | Decline with age of the respiratory chain activety in human skeletal muscle显示文摘 | Boffoli D Scacco SC Vergari RG | | 0，，： | 1 |
| 15 | Ageing is associated in females with a decline in the content and activity on the b_C1 complexin skeletal muscle mitochondria显示文摘 | Boffoli D Scacco SC Vergari RG | | 0，，： | 1 |
| 16 | Decline with age of the respiratory chain activity in human skeletal muscle显示文摘 | Boffoli D Scacco SC Vergari RG | 1994 | Biochem Biophys Acta1994，1226，： | 1 |
| 17 | Relationship between oxidative stress and 'burning mouth syn- drome' in female patients: a scientific hypothesis显示文摘 | Tatullo M Marrelli M Scacco S | 2012 | Eur Rev Med Pharmacol Sci2012，16，9： | 1 |
| 18 | Decline with age of the respiratory chain activity in human skeletal muscle显示文摘 | Boffoli D Scacco S C Vergari R | 1994 | Biochim Biophys Acta1994，1226，1： | 1 |
| 19 | Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I显示文摘 | Iuso A Scacco S Piccoli C | 2006 | J Biol Chem2006，281，10： | 1 |
| 20 | Fast power cycling test for IGBT modules in traction application显示文摘 | M Held P Jacob G Nicoletti P Scacco M H Poech | | 0，，10： | 1 |
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