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| 1 | 乙型肝炎病毒慢性感染者血清中不同类型病毒转录体的检测及其意义显示文摘目的:建立针对乙型肝炎病毒(HBV)全长型(fRNA)和顿挫型转录体(trRNA)的血清学检测方法,并探讨其临床应用价值.方法:自患者血清中提取病毒核酸,经PCR及PRT-PCR进行扩增,琼脂糖电泳显示产物,Southern印迹验证反应的特异性.取代表性产物克隆,测序.结果:在HBV慢性携带者的血清中检测到了在上述不同poly(A)位点成熟的病毒RNA.血清中fRNA的检出与e抗原阳性和较强的病毒DNA信号相对应,与转氨酶活性呈正相关,这一血清学指标反映了病毒复制;而trRNA的检出与e抗原阳性和转氨酶活性无关,不象fRNA那样依赖于血清中病毒DNA的量.二者检出率随年龄有不同变化,前者随年龄增加而进行性减低乃至转阴;而后者在10-20岁期间检出率升至80%,以后维持在较高水平.即使在某些表面抗原阴性血清中,也能检测到trRNA和不在上述两个位点成熟的病毒RNA.这些转录体在某些隐源性肝硬变和丙型肝炎患者血清中也存在.结论:病毒转录体的血清学检测有助于确定目前尚不认识的HBV感染期,可用来更准确地区分复制期和非复制期以及检出隐匿性HBV感染. | 苏勤 张伟 刘节 王淑芳 Kunio Takegoshi Claus H Schrder | 2003 | 世界华人消化杂志2003，11，2： | 16 |
| 2 | Ultrasonic distance sensors-An overview and trends显示文摘Nowadays ultrasonic distance sensors are widely used in automobiles,robotics and in industrial automation.Some functional principles of usable transducers for airborne ultrasonic distance measurements are shown.As every sensor principle,ultrasonic distance sensors have pros and cons which lead to some problems and challenges de-scribed below.For the main challenges(crosstalk and blind zone) some trends and solutions are presented. | Bernd Henning Andreas Schrder | 2011 | 电子测量与仪器学报2011，25，7： | 3 |
| 3 | Influences on development of thermal and residual stresses in quenched steel cylinders of different dimensions显示文摘 | SCHRDER R | 1985 | Materials Science and Technology1985，1，10： | 1 |
| 4 | Structure, mechanism and regulation of peroxiredoxins 显示文摘 | Wood Z A Schrder E Robin H J | 2003 | Trends in Biochemi- cal Sciences2003，28，1： | 1 |
| 5 | Percutaneous endoscopic gastrostomy in paediatric cancer patients显示文摘 | Barlaug M Kruse A Schrder H | | 0，，23： | 1 |
| 6 | Sexual function before and after radical retropubic prostatectomy: a systematic review of prognostic indicators for a successful outcome显示文摘 | Dubbelman YD Dohle GR Schrder FH | 2006 | Eur Urol2006，50，： | 1 |
| 7 | Plant polyketide synthases: A chalcone synthase-type enzyme which performs a condensation reaction with methylmalonyl- CoA in the biosynthesis of C-methylated chalcones 显示文摘 | Schrder J Raiber S Berger T | 1998 | Biochemistry1998，37，23： | 1 |
| 8 | Effects of opioid antagonists and morphine in a hippocampal hypoxia/ hypoglycemiamodel显示文摘 | Ammon-Treiber S Stolze D Schrder H | 2012 | Neuropharmacology2012，55，8： | 1 |
| 9 | The reduction of nosocomial MRSA infection in Germany:an analysis of data from the Hospital InfectionSurveillance System(HISS)between2007and 2012显示文摘 | Meyer E Schrder C Gastmeier P | 2014 | Dtsch Arztebl Int2014，111，19： | 1 |
| 10 | Heme oxygenase-1 and cardiovascular disease显示文摘 | Immenschuh S Schrder H | 2006 | Histol Histopathol2006，1，6： | 1 |
| 11 | Histological study of lumbar intervertebral disc herniation in adolescents 显示文摘 | Lee JY Emestus RI Schrder R | 2000 | Acta neurochirurgica2000，142，： | 1 |
| 12 | Autopsy-verified major pulmonary embolism after hip fracture 显示文摘 | Schrder HM Andreassen M | 1993 | Clin Orthop Relat Res1993，，293： | 1 |
| 13 | Antibiotic associated diarrhea 显示文摘 | Schrder O Gerhard R Stein J | 2006 | Z Gastroenterol2006，44，2： | 1 |
| 14 | Prevalence of mild cognitive impairment in an elderly community sample 显示文摘 | Schrder J Kratz B Pantel J | 1998 | J Neural Transm Suppl1998，54，： | 1 |
| 15 | Exploiting complex carbohydrates for microbial electricity generation: A bacterial fuel cell operating on starch显示文摘 | Niessen J Schrder U Scholz F | 2004 | ElectroehemistryCommunications2004，6，： | 1 |
| 16 | D-Type prostanoid receptor enhances the signaling of chemoattractant receptor-homologous molecule expressed on TH2cells显示文摘 | SEDEJ M SCHRDER R BELL K | 2012 | Journal of Allergy and Clinical Immunology2012，129，2： | 1 |
| 17 | DnaK, DnaJ, and GrpE from a Cellular Chaperone Machinery Capable of Repairing Heat - induced Protein Damage显示文摘 | Schrder H Langer T Hard F U | 1993 | EMBO J1993，12，11： | 1 |
| 18 | Identificationand elimination of the competing ^-acetyldiaminopentanepathway for improved production of diaminopentane bycorynebacterium glutamicum 显示文摘 | KIND S JEONG W K SCHRDER H | 2010 | Applied and Environ-mental Microbiology2010，76，15： | 1 |
| 19 | Two types of sunburn is ap-ple caused by high fruit surface (peel) temperature 显示文摘 | SCHRDER L ZHANG J G | 2001 | Plant Health Progewss2001，，10： | 1 |
| 20 | High H2Adsorption by Coordination-Framework Materials显示文摘 | Lin X Schrder M | 2006 | Angew Chem Int Ed2006，45，： | 1 |
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