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| 1 | Patterns of genomic and phenomic diversity in wine and table grapes显示文摘Grapes are one of the most economically and culturally important crops worldwide,and they have been bred for both winemaking and fresh consumption.Here we evaluate patterns of diversity across 33 phenotypes collected over a 17-year period from 580 table and wine grape accessions that belong to one of the world’s largest grape gene banks,the grape germplasm collection of the United States Department of Agriculture.We find that phenological events throughout the growing season are correlated,and quantify the marked difference in size between table and wine grapes.By pairing publicly available historical phenotype data with genome-wide polymorphism data,we identify large effect loci controlling traits that have been targeted during domestication and breeding,including hermaphroditism,lighter skin pigmentation and muscat aroma.Breeding for larger berries in table grapes was traditionally concentrated in geographic regions where Islam predominates and alcohol was prohibited,whereas wine grapes retained the ancestral smaller size that is more desirable for winemaking in predominantly Christian regions.We uncover a novel locus with a suggestive association with berry size that harbors a signature of positive selection for larger berries.Our results suggest that religious rules concerning alcohol consumption have had a marked impact on patterns of phenomic and genomic diversity in grapes. | ZoëMigicovsky Jason Sawler Kyle M Gardner Mallikarjuna K Aradhya Bernard H Prins Heidi R Schwaninger Carlos D Bustamante Edward S Buckler Gan-Yuan Zhong Patrick J Brown Sean Myles | 2017 | Horticulture Research2017，4，1： | 3 |
| 2 | Determination of the oxidation states of manganese in brain, liver, and heart mitochondria 显示文摘 | Thomas E G Lisa M M Claire E G Roman E Jason S Linas B Andrei A Sean H Karlene K G | 2004 | Journal of Neuroehemistry2004，88，： | 1 |
| 3 | Diabetes and mortality follow- ing acute coronary syndromes 显示文摘 | Sean M Garrick C Carolyn H | 2007 | JAMA2007，298，7： | 1 |
| 4 | Microwave synthesis of benchmark organo-imn complexes 显示文摘 | SEAN M G ANDREW J H | 2009 | Organometal- lics2009，28，： | 1 |
| 5 | Radiotherapy for Liver Metastases: A Review of Evidence显示文摘 | Morten H?yer Anand Swaminath Sean Bydder Michael Lock Alejandra Méndez Romero Brian Kavanagh Karyn A. Goodman Paul Okunieff Laura A. Dawson | 2012 | International Journal of Radiation Oncology Biology Physics2012，，3： | 1 |
| 6 | A spatio-temporal model of house prices in the US显示文摘 | HOLLY SEAN PESARAN M H YAMAGATA T | 2008 | Journal of Econometrics2008，158，1： | 1 |
| 7 | Suppression of acute and chronic opioid withdrawal by a selective soluble guanylyl cyclase inhibitor显示文摘 | Michael E S Sean R H Brian M | 2000 | Brain Res2000，859，： | 1 |
| 8 | A synthe- tic route to size-controlled fcc and fct FePt nanoparticles显示文摘 | Luciano E M H Nguyen H L Sean R G | 2005 | Am Chem Soc2005，127，29： | 1 |
| 9 | A mechanism-based cancer risk assessment for 1,4-dichlorobenzene 显示文摘 | Byron E B Lesa L A Sean M H | 2007 | Regulatory Toxicology and Pharmacology2007，49，： | 1 |
| 10 | An introspective survey of data scientists and their work,analyzing the analyzers 显示文摘 | Harlan H Sean M Marck V | 2013 | O''Reilly2013，2013，： | 1 |
| 11 | A mechanism-based cancer risk assessment for 1,4-dichlorobenzene显示文摘 | BYRON E B LESA L A SEAN M H | 2007 | Regulatory Toxicology and Pharmacology2007，49，： | 1 |
| 12 | A Systematic Review of Business Incubation Research显示文摘 | Sean M H David M D | 2004 | Journal of Technology Transfer2004，29，1： | 1 |
| 13 | An Exploratory Study of How Potential' Family and Household Capital' Impacts New Venture Start-Up Rates显示文摘 | PETER R CHRISTOPHER S T SEAN M H | 2009 | Family Business Review2009，22，9： | 1 |
| 14 | Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus nonseptic acute kidney injury in critical illness显示文摘 | SEAN M B MICHAEL B MICHAEL H | 2010 | Intensive care medicine2010，36，3： | 1 |
| 15 | The influence of exchange hazards and power on opportunism in outsourcing relationships显示文摘 | Sean M H Benton W C | 2012 | Journal of Operations Management2012，30，1： | 1 |
| 16 | First GOCE gravity field models derived by three different approaches显示文摘 | Roland P Sean B Federica M Christoph F Helmut G Wolf D S Eduand H Mirko R Jan M B Oleg A Mantin V Thomas F Reinhard M Ina K Fernando S and Carl C T | | 0，，11： | 1 |
| 17 | Cocondensation of organosilica hybrid shells on nanoparticle templates:a direct synthetic route to functionalized core-shell colloids显示文摘 | Simon R H Sean A D Stephen M | 2000 | Langmuir2000，16，3： | 1 |
| 18 | Bacterial templating of ordered macrostructures in silica and silicasurfactant mesophases 显示文摘 | Sean A D Sandra L B Nell H M | 1997 | Nature1997，385，66116619： | 1 |
| 19 | Drained shear strength parameters for analysis of landslides 显示文摘 | Timothy D S Choi H Sean M C | 2005 | Journal of Geotechnical and Geoenvironmental Engineering2005，31，5： | 1 |
| 20 | The economics of parking provision for the morning commute显示文摘 | Qian Zhen(Sean) Xiao Feng(Evan) Zhang H M | 2011 | Transportation Research Part A:Policy and Practice2011，45，9： | 1 |
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