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| 1 | Updated Kimura-Takemoto classification of atrophic gastritis显示文摘BACKGROUND The Updated Sydney system for visual evaluation of gastric mucosal atrophy viaendoscopic observation is subject to sampling error and interobserver variability.The Kimura-Takemoto classification system was developed to overcome theselimitations.AIMTo compare the morphological classification of atrophic gastritis between theKimura-Takemoto system and the Updated Sydney system.METHODSA total of 169 patients with atrophic gastritis were selected according to diagnosisby the visual endoscopic Kimura-Takemoto method. Following the UpdatedKimura-Takemoto classification system, one antrum biopsy and five gastriccorpus biopsies were taken according to the visual stages of the Kimura-Takemoto system. The Updated Kimura-Takemoto classification system was thenapplied to each and showed 165 to have histological mucosal atrophy;theremaining 4 patients had no histological evidence of atrophy in any biopsy. The Updated Kimura-Takemoto classification was verified as a referencemorphological method and applied for the diagnosis of atrophic gastritis. Addingone more biopsy from the antrum to the six biopsies according to the Updated Kimura-Takemoto classification, constitutes the updated combined Kimura-Takemoto classification and Sydney system.RESULTSThe sensitivity for degree of mucosal atrophy assessed by the Updated Sydneysystem was 25% for mild, 36% for moderate, and 42% for severe, when comparedwith the Updated Kimura-Takemoto classification of atrophic gastritis formorphological diagnosis. Four types of multifocal atrophic gastritis wereidentified: sequential uniform (type 1;in 28%), sequential non-uniform (type 2;in7%), diffuse uniform (type 3;in 23%), diffuse non-uniform (type 4;in 24%), and'alternating atrophic – non-atrophic' (type 5;in 18%). The pattern of the spread ofatrophy, sequentially from the antrum to the cardiac segment of the stomach,which was described by the Updated Kimura-Takemoto system, washistologically confirmed in 82% of cases evaluated.CONCLUSIONThe Updated Sydney system is significantly inferior to the Updated Kimura-Takemoto classification for morphological verification of atrophic gastritis. | Sergey M Kotelevets Sergey A Chekh Sergey Z Chukov | 2021 | World Journal of Clinical Cases2021，9，13： | 8 |
| 2 | Contribution of functional KIR3DL1 to ankylosing spondylitis显示文摘Increasing evidence points to a role for killer immunoglobulin-like receptors(KIRs)in the development of autoimmune diseases.In particular,a positive association of KIR3DS1(activating receptor)and a negative association of KIR3DL1(inhibitory receptor)alleles with ankylosing spondylitis(AS)have been reported by several groups.However,none of the studies analyzed these associations in the context of functionality of polymorphic KIR3DL1.To better understand how the KIR3DL1/3DS1 genes determine susceptibility to AS,we analyzed the frequencies of alleles and genotypes encoding functional(KIR3DL1*F)and non-functional(KIR3DL1*004)receptors.We genotyped 83 AS patients and 107 human leukocyte antigen(HLA)-B27-positive healthy controls from the Russian Caucasian population using a two-stage sequence-specific primer PCR,which distinguishes KIR3DS1,KIR3DL1*F and KIR3DL1*004 alleles.For the patients carrying two functional KIR3DL1 alleles,those alleles were additionally genotyped to identify KIR3DL1*005 and KIR3DL1*007 alleles,which are functional but are expressed at low levels.KIR3DL1 was negatively associated with AS at the expense of KIR3DL1*F but not of KIR3DL1*004.This finding indicates that the inhibitory KIR3DL1 receptor protects against the development of AS and is not simply a passive counterpart of the segregating KIR3DS1 allele encoding the activating receptor.However,analysis of genotype frequencies indicates that the presence of KIR3DS1 is a more important factor for AS susceptibility than the absence of KIR3DL1*F.The activation of either natural killer(NK)or T cells via the KIR3DS1 receptor can be one of the critical events in AS development,while the presence of the functional KIR3DL1 receptor has a protective effect.Nevertheless,even individuals with a genotype that carried two inhibitory KIR3DL1 alleles expressed at high levels could develop AS. | Ivan V Zvyagin Ilgar Z Mamedov Olga V Britanova Dmitriy B Staroverov Evgeni L Nasonov Anna G Bochkova Anna V Chkalina Alexei A Kotlobay Dmitriy O Korostin Denis V Rebrikov Sergey Lukyanov Yuri B Lebedev Dmitriy M Chudakov | 2010 | Cellular & Molecular Immunology2010，7，6： | 5 |
| 3 | The heat capacities of titanium sfiici6es TisSi3,TiSi and TiSi2 显示文摘 | Shilpa A Eric J C Sergei Z | | Journal of Aoys and Compounds0，314，： | 1 |
| 4 | Exploiting Growing Stock Volume Maps for Large Scale Forest Resource Assessment: Cross- Comparisons of ASAR- and PALSAR-Based GSV Estimates with Forest Inventory in Central Siberia 显示文摘 | Christian H Mikhail K Sergey B Vasily Z Dmitry S Anatoly S Christiane S | 2014 | Forests2014，5，7： | 1 |
| 5 | Glucose and tolbutamide induce apoptosis in pancreatic-cells: a process dependent on intracellular Ca2+ concentration显示文摘 | Sergei VZ Boris Z Martin K Sten O Per-Olof B | 1998 | J Biol Chem1998，273，33： | 1 |
| 6 | Density-Dependent Liquid Nitromethane Decomposition: Molecular Dynamics Simulations Based on ReaxFF 显示文摘 | NAOMI R SERGEY V Z | 2011 | Journal of Physical Chemistry A2011，115，10： | 1 |
| 7 | Use of 16S rRNA, 23S rRNA, and gyrB gene sequence analysis to determine phylogenetic relationships of Bacillus cereus group microorganisms显示文摘 | SERGEI G B YURI P L VLADIMIR Z | 2004 | J Clinical Microbiology2004，42，8： | 1 |
| 8 | Water channels(Aquaporins)and their role for post-natal adaptation显示文摘 | Marina Z Sergey Z Anita A | 2005 | Pediatric Res2005，，57： | 1 |
| 9 | Viscoaoustic modeling and imaging using low-rank approximation显示文摘 | Sun J Z Zhu T Y Sergey F | 2014 | Ex- panded Abstracts of 84th Annual Internat SEG Mtg2014，，： | 1 |
| 10 | CVRQD ab initio ground-state adiabatic potential energy surfaces for the water molecule显示文摘 | SERGEI V S NIKOLAI F Z | 2006 | Journal of Chemical Physics2006，125，20： | 1 |
| 11 | Water channels(Aquaporins)and their role for postnatal adaptation显示文摘 | Sergey Z Anita A | 2005 | Pediatric Research2005，57，： | 1 |
| 12 | 显示文摘 | AlviseP SergeiY etal | 2002 | JCatal2002，211，： | 1 |
| 13 | Antifouling properties of zinc oxide nanorod coatings 显示文摘 | Marwan A F Sergey D Myo T Z M | 2014 | Biofouling2014，30，7： | 1 |
| 14 | Precise radiolarian age constraints on the timing of ophiolite generation and sedimentation in the Dazhuqu terrane,Yarlung-Tsangpro suture zone,Tibet显示文摘 | Sergey V Z Jonathan C A Alexandra V A | 2003 | Journal of the Geological Society2003，160，： | 1 |
| 15 | Bainang terrane,Yarlung-Tsangpo suture,southern Tibet (Xizang,China):a record of intra-Neotethyan subduction-accretion processes preserved on the roof of the world显示文摘 | Sergey V Z Jonathan C A Alexandra V A | 2004 | Journal of the Geological Society2004，161，： | 1 |
| 16 | Water channels (Aquaporins)and their role for postnatal adaptation显示文摘 | Marina Z Sergey Z Anita A | 2005 | Pediatric Res2005，57，： | 1 |
| 17 | Identification of rifampin-resi- stant mycobacterium tuberculosis strains by hybridization,PCR, and ligase detection reaction on oligonucleotide microchips显示文摘 | Vladimir M Sergey L Dimitry G Alexander S Boris S Nikolai C Olga S Olga I Arkadii M Vitalii L Mikhall V Mikhail P Larisa C Vladislav E Alexander Z Andrei M | 2001 | Journal of Clinical Microbiology2001，39，7： | 1 |
| 18 | Hydrodechlorination and hydrogenation over raney-Ni under multiphase conditions:role of multiphase environment in reaction kinetics and selectivity显示文摘 | SERGEI Z ALVISE P SERGEI Y | 2002 | Journal of Catalysis2002，211，： | 1 |
| 19 | Asymmetric trans- mission in planar chiral split-ring metamaterials: Micro- scopic Lorentz-theory approach显示文摘 | Andrey V N Vladimir M G Sergei V Z | 2012 | Physical Review B2012，86，07： | 1 |
| 20 | Dramatic Changes in the Prevalence of Helicobacter pylori Infection During Childhood: A 10-year Follow-up Study in Russia显示文摘 | Mikhail A Tkachenko Nurgalieva Z Zhannat Lev V Erman Elena L Blashenkova Sergey V Isachenko Olga B Isachenko David Y Graham Hoda M Malaty | 2007 | Journal of Pediatric Gastroenterology and Nutrition2007，，4： | 1 |
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