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| 1 | Dynamic roles of angiopoietin-like proteins 1, 2, 3, 4, 6 and 7 in the survival and enhancement of ex vivo expansion of bone-marrow hematopoietic stem cells显示文摘Recent advances in hematopoietic stem cells(HSCs)expansion by growth factors including angiopoietin-like proteins(Angptls)have opened up the possibility to use HSCs in regenerative medicine.However,the unavailability of true in vitro HSCs expansion by these growth factors has limited the understanding of the cellular and molecular mechanism of HSCs expansion.Here,we report the functional role of mouse Angptls 1,2,3,4,6 and 7 and growth factors SCF,TPO,IGF-2 and FGF-1 on purified mouse bone-marrow(BM)Lineage-Sca-1+(Lin-Sca-1+)HSCs.The recombinant retroviral transduced-CHO-S cells that secrete Angptls in serum-free medium were used alone or in combination with growth factors(SCF,TPO,IGF-2 and FGF-1).None of the Angptls stimu-lated HSC proliferation,enhanced or inhibited HSCs colony formation,but they did support the survival of HSCs.By contrast,any of the six Angptls together with saturating levels of growth factors dramatically stimulated a 3-to 4.5-fold net expansion of HSCs compared to stimulation with a combination of those growth factors alone.These findings lead to an understanding of the basic function of Angptls on signaling pathways for the survival as well as expansion of HSCs in the bone marrow niche. | Shahina Akhter MdMashiar Rahman Hyun Seo Lee Hyeon-Jin Kim Seong-Tshool Hong | 2013 | Protein & Cell2013，4，3： | 2 |
| 2 | Prevalence of Barrett's esophagus in patients with moderate to severe erosive esophagitis显示文摘AIM: To investigate the proportion of patients with moderate-severe erosive esophagitis (EE) who will have Barrett's esophagus (BE) after healing of inflammation. METHODS: Patients with EE of Los Angeles (LA) class B, C and D who underwent follow-up endoscopy documenting complete mucosal healing. RESULTS: A total of 86/169 patients were suspected of having BE (38 before healing and 48 after healing of EE) and, 46/86 eventually had the histological confirmation. At index esophago-gastro-duodenoscopy (EGD), BE was suspected in 38/169 (22%), and ultimately, histologically confirmed in 20 of these. In 11 patients where biopsies were performed in the presence of inflammation, BE was detected in 2 and missed in 5 (including 2 dysplasias). In 131/169 patients (77.5%), BE was not suspected at index EGD. After healing of EE though, 48 patients had suspicion of BE who underwent biopsies, and in 26 of these histology was positive for BE. The length of inflammation had a linear correlation with the length of BE (P = 0.01). Out of multiple variables to predict BE, only the suspicion at index endoscopy was statistically significant (P = 0.01). CONCLUSION: BE was seen in 46/169 (27%) patients with EE of LA class B, C and D. The length of EE can predict the length of underlying BE segment.Even when suspected, BE and associated dysplasia can be missed in the presence of inflammation; therefore, repeat evaluation should be considered after complete healing of esophagitis. | Nooman Gilani Richard D Gerkin Francisco C Ramirez Shahina Hakim Adam C Randolph | 2008 | World Journal of Gastroenterology2008，14，22： | 2 |
| 3 | Comparative genomic analyses of Streptococcus pseudopneumoniae provide insight into virulence and commensalism dynamics显示文摘 | Shahinas D Thornton CS Tamber GS | 2013 | PLoS One2013，8，65： | 1 |
| 4 | Marchiafava-Bignami disease:Role 6f neuroimaging in the diagno- sis andmanagement of acute disease 显示文摘 | Shahina Bano Shibani Mehra Sacchida Nand Yadav | 2009 | Neurology India2009，57，： | 1 |
| 5 | Transfusion associated CMV infection: Transfusion strategies for high risk patients显示文摘 | Munira J Shahina T Abdul A | 2010 | Bangladesh Journal of Medical Microbiology2010，4，2： | 1 |
| 6 | Effect of flavonoids on the oxidative stability of corn oil during deep frying 显示文摘 | Shahina Naz Rahmanullah Siddiqi Syed Asad Sayeed | 2008 | International Journal of Food Science and Technology2008，，43： | 1 |
| 7 | Intercellular Cell Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and Regulated on Activation Normal T Cell Expressed and Secreted Are Expressed by Human Breast Carcinoma Cells and Support Eosinophil Adhesion and Activation显示文摘 | Shahina Ali Jaswinder Kaur Kamala D. Patel | 2000 | The American Journal of Pathology2000，，1： | 1 |
| 8 | Novel mutations in a patient isolate of streptococcus agalactiae with reduced penicillin susceptibility emerging after long-term oral suppressive therapy显示文摘 | Longtin J Vermeiren C Shahinas D | | 0，，： | 1 |
| 9 | Expression of multiple insecticidal genes confers broad resistance against a range of different rice pests显示文摘 | Shahina Bano Maqbool Sheikh Riazuddin Nguyen Thi Loc Angharad M.R. Gatehouse John A. Gatehouse Paul Christou | 2001 | Molecular Breeding2001，，1： | 1 |
| 10 | Detection of sprout damage in Canada western red spring wheat with multiple wavebands u- sing visible-near-infrared hyperspectral in aging显示文摘 | Xing J Symons S Shahina M | 2010 | Biosystems Engineering2010，106，2： | 1 |
| 11 | A compendium of the genus Seinura Fuchs,1931(Nematoda:Aphelenchida)显示文摘 | Shahina F Hunt D J | 1995 | Afro-Asian Journal of Nematology1995，5，2： | 1 |
| 12 | 基于GIS的巴基斯坦北部文化遗址时空分布特征及保护对策显示文摘巴基斯坦北部地区是历史上犍陀罗文化的中心区域,拥有大量的印度教、佛教和伊斯兰教文化遗址。借助考古文献资料、数字高程模型以及野外实地调查与验证数据,运用GIS空间分析方法,对巴基斯坦北部地区印度教、佛教和伊斯兰教文化遗址的时空分布特征、保存现状进行研究,并提出相应保护对策。结果表明:巴基斯坦北部地区先后经历了印度教文化、佛教文化、伊斯兰教文化的传入、兴衰等演变过程。核密度估计显示3种文化遗址分布范围、聚集程度有所不同,但都以伊斯兰堡周边区域聚集程度最高。基于高分辨率的DEM分析表明,90%以上的文化遗址距离河流小于800 m,反映其位置选择对于河流的依赖与需求。从分布的高程看,3种文化遗址大多数在800 m以下、坡度范围在0°~10°之间,主要沿河道和交通要道分布。统计数据表明:伊斯兰教遗址数目最多,佛教遗址次之,印度教遗址最少,反映遗址保存的数量随时间而变化。由于自然因素和人类活动,一些文化遗址如古佩拉、维吉等保存状况较差,亟待加大保护力度。针对遗址目前的保存状况与面临的风险,提出对应的保护措施。 | 姜纯 骆磊 Shahina Tariq Muhammad Ali 姚娅 王心源 | 2021 | 中国科学院大学学报(中英文)2021，38，4： | 1 |
| 13 | Studies on electrodeposition of FeW alloys for fuel cell applications显示文摘 | Tharamani C N Beera Parthasarathi Jayaram V Begum Noor Shahina | 2006 | Applied Surface Science2006，253，： | 1 |
| 14 | Expression of multiple insecticidal genes confers broad resistance against a range of different rice pests显示文摘 | Shahina Bano Maqbool Sheikh Riazuddin Nguyen Thi Loc Angharad M.R. Gatehouse John A. Gatehouse Paul Christou | 2001 | Molecular Breeding2001，，1： | 1 |
| 15 | Detection of sprout damage in Canada Western Red Spring wheat with mul- tiple wavebands using visible/near - infrared hyperspectral imaging 显示文摘 | Xing J Symons S Shahina M | 2010 | Biosystems Engineering2010，106，2： | 1 |
| 16 | p38 MAP kinase regulates rapid matrix metalloproteinase-9 release from eosinophils显示文摘 | Shahina W Susan L Subhadeep C | 2004 | Bioehem Biophys Rescommun2004，315，2： | 1 |
| 17 | Oxidative stability of olive, corn and soybean oil under different conditions 显示文摘 | Shahina Naz Hina Sheikh Rahmanullah Siddiqi | 2004 | Food Chemistry2004，88，： | 1 |
| 18 | Imaging of the pituitary:Recent advances 显示文摘 | Vikas Chaudhary Shahina Bano | 2011 | India Journal of Endocrinology and Metabolism2011，15，： | 1 |
| 19 | Genomewide dissection of globally emergent muhi-drug resistant semtype 19A Streptococcus pneumoniae显示文摘 | Pillai DR Shahinas D Buzina A | 2009 | BMC Genomics2009，10，： | 1 |
| 20 | Deteri- oration of olive, corn and soybean oils due to air, light, heat and deep-frying显示文摘 | Shahina Naz Rahmanullah Siddiqi Hina Sheikh | 2005 | Food Research International2005，38，12： | 1 |
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