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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Ocular Findings Among Thalassemia Patients显示文摘 | Ali Taher Ziad Bashshur Wael A. Shamseddeen Raja-Elie E. Abdulnour Elie Aoun Suzann Koussa Patrick Baz | 2006 | American Journal of Ophthalmology2006，，4： | 1 |
| 3 | Behacioral modeling to guide adherence to fluid control on hemodialysispatients显示文摘 | Ghaddar S Shamseddeen W Elzein Z | 2009 | J Ren Nutr2009，2，19： | 1 |
| 4 | Modulation of COX-2 expression by statins in human monocytic cells显示文摘 | Habib A Shamseddeen I Nasrallah MS | 2007 | FASEB J2007，21，8： | 1 |
| 5 | Gross lower gastrointestinal bleeding in patients on anticoagulant and/or anti-platelet therapy:endoscopic findings, management, and clinical Outcomes 显示文摘 | Hashash JG Shamseddeen W Skoury A | 2009 | J Clin Gastroenterol2009，43，1： | 1 |
| 6 | Adjunctive sleep medications and depression outcome in the treatment of serotonin-selective reuptake inhibitor resistant depression in adolescents study显示文摘 | SHAMSEDDEEN W CLARKE G KELLER MB | 2012 | J Child Adolesc Psychopharmacol2012，22，1： | 1 |
| 7 | Thrombophilic risk factors among 16 Lebanese patients with cerebral venous and sinus thrombosis显示文摘 | Otrock ZK Taher AT Shamseddeen WA | 2008 | J Thromb Thrombolysis2008，26，1： | 1 |
| 8 | Adjunctive sleep medi- cations and depression outcome in the treatment of serotonin-selee- tive reuptake inhibitor resistant depression in adolescents study 显示文摘 | Shamseddeen W Clarke G Keller MB | 2012 | J Child Adolesc Psychopharmacol2012，22，1： | 1 |
| 9 | Upper Gastrointestinal Bleeding in Patients With Acute Coronary Syndromes: Clinical Predictors and Prophylactic Role of Proton Pump Inhibitors显示文摘 | Kassem Barada Wassef Karrowni Mouhamad Abdallah Wael Shamseddeen Ala I. Sharara Habib A. Dakik | 2008 | Journal of Clinical Gastroenterology2008，，4： | 1 |
| 10 | Elevated levels of circulating procoagulant microparticles in patients with 显示文摘 | Habib A Kunzelmann C Shamseddeen W | 2008 | Haematologica2008，93，6： | 1 |
| 11 | TNF polymorphisms in patients with Behcet disease:a meta-analysis显示文摘 | Touma Z Farra C Hamda A Shamseddeen W Uthman I Hourani H | | 0，，02： | 1 |
| 12 | Adjunctive sleep medications and depression outcome in the treatment of serotonin- selective reuptake inhibitor resistant depression in adolescents study显示文摘 | Shamseddeen W Clarke G Keller MB | 2012 | J Child Adolesc Psychopharmacol2012，22，1： | 1 |
| 13 | Greater than expected prevalence of pseudotumor cerebri: a prospective study显示文摘 | Hamdallah IN Shamseddeen HN Getty JL | 2013 | Surg Obes Relat Dis2013，9，1： | 1 |
| 14 | Gross lower gastrointestinal bleeding in patients on anticoagulant and/or antiplatelet therapy: endoscopic findings, management, and clinical outcomes显示文摘 | Hashash JG Shamseddeen W Skoury A | 2009 | J Clin Gastroenterol2009，43，1： | 1 |
| 15 | Greater than expected prevalence of pseudotumor cerebri , a prospective study显示文摘 | Hamdallah IN Shamseddeen HN GettyJL | | Surg Obes Relat Dis0，9，1： | 1 |
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