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| 1 | Efficacy of Atorvastatin combined with adipose-derived mesenchymal stem cell transplantation on cardiac function in rats with acute myocardial infarction显示文摘间充质的干细胞(MSC ) 广泛地被申请了在尖锐心肌的梗塞(AMI ) 以后的 cardiomyocytes 损失的恢复。然而,在 ischemic 心疾病的 MSC 的最佳的治疗学的功效被他们的差的幸存和低区分的率妨碍了。因此, MSC 幸存的改进和区分的率被保证并且为在 AMI 的 MSC 的功效批评。在这份报纸,从腹股沟的胖纸巾作为脂肪质导出被称为间充质的干细胞(ASC ) 的老鼠孤立的 MSC,和 ASC 的第四个段落被文化 co 在一个 transwell 系统与 cardiomyocytes 预先指定作为 co-ASCs 称为。十四天以后, GATA-4 (一个抄写因素) 和心脏的 troponin -- 我被细胞的 immunofluorescence 检测。Atorvastatin (Ator 组) 或车辆(控制组) 在老鼠在 AMI 生产以后为开始的 24 h 被管理。十四天以后,煽动性的参数和心脏的功能被评估。另外的幸存老鼠与 1 普物敭 ? 潴戠 ? 的一个总数被注射 ? 楤敲瑣琠牡敧 ? 敧敮漠 ? 業??? 祢攠桮湡散 ? 牧敥 ? 汦潵敲 ' 諟?牰瑯楥? 敲潰瑲牥攠灸牥浩湥吗? | Anping Cai Dongdan Zheng Yugang Dong Ruofeng Qiu Yuli Huang Yuanbin Song Zhigao Jiang Shaoqi Rao Xinxue Liao Jian Kuang Gang Dai Weiyi Mai | 2011 | Acta Biochimica et Biophysica Sinica2011，43，11： | 16 |
| 2 | Flight strategy optimization for high-altitude long-endurance solar-powered aircraft based on Gauss pseudo-spectral method显示文摘Solar-powered aircraft have attracted great attention owing to their potential for longendurance flight and wide application prospects.Due to the particularity of energy system,flight strategy optimization is a significant way to enhance the flight performance for solar-powered aircraft.In this study,a flight strategy optimization model for high-altitude long-endurance solar-powered aircraft was proposed.This model consists of three-dimensional kinematic model,aerodynamic model,energy collection model,energy store model and energy loss model.To solve the nonlinear optimal control problem with process constraints and terminal constraints,Gauss pseudo-spectral method was employed to discretize the state equations and constraint equations.Then a typical mission flying from given initial point to given final point within a time interval was considered.Results indicate that proper changes of the attitude angle contribute to increasing the energy gained by photovoltaic cells.Utilization of gravitational potential energy can partly take the role of battery pack.Integrating these two measures,the optimized flight strategy can improve the final state of charge compared with current constant-altitude constant-velocity strategy.The optimized strategy brings more profits on condition of lower sunlight intensity and shorter daytime. | Shaoqi WANG Dongli MA Muqing YANG Liang ZHANG Guanxiong LI | 2019 | Chinese Journal of Aeronautics2019，32，10： | 15 |
| 3 | Effect of slurry conditioning on flocculant-aided filtration of coal tailings studied by low-field nuclear magnetic resonance and X-ray micro-tomography显示文摘The present work aimed to study the effect of slurry conditioning on flocculant-aided filtration of coal tailings by the analysis of filtration kinetics and filter cake structure.Laboratory filtration tests of the coal tailings showed that both the shear rate and agitation time have significant effects on filtration rate and cake moisture.Moderate agitation at the shear rate of 92 s^-1 was favorable for fast filtration,but high cake moisture was encountered.The low-field 1H nuclear magnetic resonance(NMR)measurements of the filter cake showed that the slurry conditioning has a significant effect on the residual water in large pores and a negligible effect on the residual water in small pores.The X-ray micro-tomography(XRM)measurements indicated that the filter cake formed at the shear rate of 92 s^-1 has more macro-pores and higher porosity than that formed at the shear rate of 53 s1,hence more residual water was entrapped in filter cake.The slurry conditioning in the presence of flocculant will change the structure of filter cake and affect the filtration performance.There was a paradox between fast filtration rate and low filter cake moisture.The findings enable better understanding of the effect of slurry conditioning on flocculant-aided filtration of coal tailings. | Pengfei Hu Long Liang Guangyuan Xie Shaoqi Zhou Yaoli Peng | 2020 | International Journal of Mining Science and Technology2020，30，6： | 12 |
| 4 | Dynamic simulation of aerial towed decoy system based on tension recurrence algorithm显示文摘Dynamic model of aerial towed decoy system is established and simulations are performed to research the dynamic characteristics of the system. Firstly, Kinetic equations based on spinor are built, where the cable is discretized into a number of rigid segments while the decoy is modeled as a rigid body hinged on the cable. Then tension recurrence algorithm is developed to improve computational efficiency, which makes it possible to predict the dynamic response of aerial towed decoy system rapidly and accurately. Subsequently, the efficiency and validity of this algorithm are verified by comparison with Kane's function and further validated by wind tunnel tests.Simulation results indicate that the distance between the towing point and the decoy's center of gravity is suggested to be 5%–20% of the length of decoy body to ensure the stability of system.In up-risen maneuver process, the value of angular velocity is recommended to be less than0.10 rad/s to protect the cable from the aircraft exhaust jet. During the turning movement of aircraft, the cable's extent of stretching outwards is proportional to the aircraft's angular velocity.Meanwhile, the decoy, aircraft and missile form a triangle, which promotes the decoy's performance. | Ma Dongli Wang Shaoqi Yang Muqing Dong Yongpan | 2016 | Chinese Journal of Aeronautics2016，29，6： | 5 |
| 5 | Serum semaphorin 4C as a diagnostic biomarker in breast cancer:A multicenter retrospective study显示文摘Background:To date,there is no approved blood-based biomarker for breast cancer detection.Herein,we aimed to assess semaphorin 4C(SEMA4C),a pivotal protein involved in breast cancer progression,as a serum diagnostic biomarker.Methods:We included 6,213 consecutive inpatients from Tongji Hospital,Qilu Hospital,and Hubei Cancer Hospital.Training cohort and two validation cohorts were introduced for diagnostic exploration and validation.A pan-cancer cohort was used to independently explore the diagnostic potential of SEMA4C among solid tumors.Breast cancer patients who underwent mass excision prior to modified radical mastectomy were also analyzed.We hypothesized that increased pretreatment serum SEMA4C levels,measured using optimized in-house enzymelinked immunosorbent assay kits,could detect breast cancer.The endpoints were diagnostic performance,including area under the receiver operating characteristic curve(AUC),sensitivity,and specificity.Post-surgery pathological diagnosis was the reference standard and breast cancer staging followed the TNM classification.There was no restriction on disease stage for eligibilities.Results:We included 2667 inpatients with breast lesions,2378 patients with other solid tumors,and 1168 healthy participants.Specifically,118 patients with breast cancer were diagnosed with stage 0(5.71%),620 with stage I(30.00%),966 with stage II(46.73%),217 with stage III(10.50%),and 8 with stage IV(0.39%).Patients with breast cancer had significantly higher serum SEMA4C levels than benign breast tumor patients and normal controls(P<0.001).Elevated serum SEMA4C levels had AUC of 0.920(95%confidence interval[CI]:0.900–0.941)and 0.932(95%CI:0.911–0.953)for breast cancer detection in the two validation cohorts.The AUCs for detecting early-stage breast cancer(n=366)and ductal carcinoma in situ(n=85)were 0.931(95%CI:0.916–0.946)and 0.879(95%CI:0.832–0.925),respectively.Serum SEMA4C levels significantly decreased after surgery,and the reduction was more striking after modified radical mastectomy,compared with mass excision(P<0.001).The positive rate of enhanced serum SEMA4C levels was 84.77%for breast cancer and below 20.75%for the other 14 solid tumors.Conclusions:Serum SEMA4C demonstrated promising potential as a candidate biomarker for breast cancer diagnosis.However,validation in prospective settings and by other study groups is warranted. | Ya Wang Long Qiao Jie Yang Xiong Li Yaqi Duan Jiahao Liu Shaoqi Chen Huayi Li Dan Liu Tian Fang Jingjing Ma Xiaoting Li Fei Ye Junxiang Wan Juncheng Wei Qin Xu Ensong Guo Ping Jin Mingfu Wu Lin Zhang Yun Xia Yaqun Wu Jun Shao Yaojun Feng Qing Zhang Zongyuan Yang Gang Chen Qinghua Zhang Xingrui Li Shixuan Wang Junbo Hu Xiaoyun Wang Mona P.Tan Kazuaki Takabe Beihua Kong Qifeng Yang Ding Ma Qinglei Gao | 2021 | Cancer Communications2021，41，12： | 3 |
| 6 | Effects of cutoff thresholds for minor allele frequencies on HapMap resolution: A real dataset-based evaluation of the Chinese Han and Tibetan populations显示文摘Genomic variation is the genetic basis of phenotypic diversity among individuals, including variation in disease susceptibility and drug response. The greatest promise of the International HapMap is to provide roadmaps for identifying genetic variants predisposing to complex diseases. Single nucleotide polymorphism (SNP) is the fundamental element of the HapMap. Allele frequency of SNPs is one of the major factors affecting the resulting HapMap, being the factor upon which linkage disequilibrium (LD) is calculated, haplotypes are constructed, and tagging SNPs (tagSNPs) are selected. The cutoff thresholds for the frequency of minor alleles used in the making of the map therefore have profound effects on the resolution of that map. To date most researchers have adopted their own cutoff thresholds, and there has been little real dataset-based evaluation of the effects of different cutoff thresholds on HapMap resolution. In an attempt to assess the implications of different cutoff values, we analyzed our own data for the centromeric genes on Chromosome 15 in Chinese Han and Tibetan populations, with respect to minor allele frequency cutoff values of ≥0.01 (0.01 group), ≥0.05 (0.05 group), and ≥0.10 (0.10 group), and constructed HapMaps from each of the datasets. The resolution, study power and cost-effectiveness for each of the maps were compared. Our results show that the 0.01 threshold pro- vides the greatest power (P = 0.019 in Han and P = 0.029 in Tibetan for 0.01 vs. 0.05 threshold) and detects most population-specific haploypes (P = 0.012 for 0.01 vs. 0.05 threshold). However, in the regions studied, the 0.05 cutoff threshold did not significantly increase power above the 0.10 threshold (P = 0.191 in Han; 1.000 in Tibetans), and did not improve resolution over the 0.10 value for population-specific haplotypes (P = 0.592) neither. Furthermore the 0.05 and 0.10 values produced the same figures for tagging efficiency, LD block number, LD length, study power and cost-savings in the Tibetan population. These results suggest that a lower cutoff value is more appropriate for studies in which population-specific haplotypes are crucial, and that the most appropriate cutoff value may differ between populations. Due to the limited genes studied in this project more studies should be conducted to further address this important issue. | XIONG ShiYi HAO YuanTao RAO ShaoQi HUANG WeiJun HU Bin Labu Pubuzhuoma Gesangzhuogab WANG YiMing | 2009 | Chinese Science Bulletin2009，54，12： | 3 |
| 7 | Identifying disease feature genes based on cellular localized gene functional modules and regulation networks显示文摘Identifying disease-relevant genes and functional modules, based on gene expression pro- files and gene functional knowledge, is of high im- portance for studying disease mechanisms and sub- typing disease phenotypes. Using gene categories of biological process and cellular component in Gene Ontology, we propose an approach to selecting func- tional modules enriched with differentially expressed genes, and identifying the feature functional modules of high disease discriminating abilities. Using the differentially expressed genes in each feature module as the feature genes, we reveal the relevance of the modules to the studied diseases. Using three data- sets for prostate cancer, gastric cancer, and leukemia, we have demonstrated that the proposed modular approach is of high power in identifying functionally integrated feature gene subsets that are highly rele- vant to the disease mechanisms. Our analysis has also shown that the critical disease-relevant genes might be better recognized from the gene regulation network, which is constructed using the characterized functional modules, giving important clues to the concerted mechanisms of the modules responding to complex disease states. In addition, the proposed approach to selecting the disease-relevant genes byjointly considering the gene functional knowledge suggests a new way for precisely classifying disease samples with clear biological interpretations, which is critical for the clinical diagnosis and the elucidation of the pathogenic basis of complex diseases. | ZHANG Min ZHU Jing GUO Zheng LI Xia YANG Da WANG Lei RAO Shaoqi | 2006 | Chinese Science Bulletin2006，51，15： | 3 |
| 8 | Internal field study of 21700 battery based on long-life embedded wireless temperature sensor显示文摘The safety of lithium-ion batteries is an essential concern where instant and accurate temperature sensing is critical.It is generally desired to put sensors inside batteries for instant sensing.However,the transmission of internal measurement outside batteries without interfering their normal state is a non-trivial task due to the harsh electrochemical environment,the particular packaging structures and the intrinsic electromagnetic shielding problems of batteries.In this work,a novel in-situ temperature sensing framework is proposed by incorporating temperature sensors with a novel signal transmission solution.The signal transmission solution uses a self-designed integrated-circuit which modulates the internal measurements outside battery via its positive pole without package breaking.Extensive experimental results validate the noninterference properties of the proposed framework.Our proposed in-situ temperature measurement by the self-designed signal modulation solution has a promising potential for in-situ battery health monitoring and thus promoting the development of smart batteries. | Le Yang Na Li Likun Hu Shaoqi Wang Lin Wang Jiang Zhou Wei-Li Song Lei Sun Tai-Song Pan Hao-Sen Chen Daining Fang | 2021 | Acta Mechanica Sinica2021，37，6： | 3 |
| 9 | A feature ensemble technology to identify molecular mechanisms for distinction between multiple subtypes of lymphoma显示文摘由于复杂性和生物显型的基因异质,柔韧的计算途径是合乎需要的与多重分类器,数据结构的不安,和生物解释完成高归纳性能。这研究的目的是扩大我们的发达整体决定途径区分多重异构的显型并且阐明缠绕子类型的内在的分子的桥。我们的工作识别支撑的重要分子的机制(疾病相关的基因和功能) 为在多重显型之间的区别的复杂分子的机制。特征基因和我们的方法识别的层次基因核心在多重显型的分类完成了高精确性。结果证明建议分析策略在生物子类型的分类并且在在临床的显型之间的分子的连接的解释可行、强大。有基因本体论的生物解释为一些淋巴瘤子类型揭示了一致基因小径。 | Yueying Yang Haiyun Wang Xia Li Xue Xiao Su Fei Chuanxing Li Hongzhi Wang Shaoqi Rao Yadong Wang | 2008 | Progress in Natural Science:Materials International2008，18，12： | 2 |
| 10 | Multi-level modulation scheme based on PAK algorithm for optical camera communications显示文摘In an optical camera communication(OCC) system, multi-level modulation is essential for data rate enhancement with the finite frame rate of the receiving camera constraint, where the K-means algorithm is widely used as a thresholding scheme. The result of K-means clustering is sensitive to initial cluster centers. In this paper, we propose a multi-level modulation scheme utilizing the pilot-aided K-means(PAK) algorithm. PAK algorithm innovates in both obtaining the state of the stripes propagated through the optical channel under different environments and overcoming the susceptibility of K-means. Our scheme could prompt data rate and improve the performance of OCC. Finally, non-orthogonal multiple access(NOMA) pattern is designed based on the proposed scheme to achieve multiplex communications. | WU Jing CHI Xuefen JI Fenglei JIANG Keyu CHEN Shaoqi LI Shuai | 2022 | Optoelectronics Letters2022，18，3： | 2 |
| 11 | Removal of humic substances from landfill leachate by Fenton oxidation and coagulation显示文摘 | Yanyu Wu Shaoqi Zhou Fanghui Qin Huaping Peng Yanglan Lai Yiming Lin | 2010 | Process Safety and Environmental Protection2010，，4： | 2 |
| 12 | Fast start-up of ANAMMOX reactor: Operational strategy and some characteristics as indicators of reactor performance显示文摘 | Huosheng Li Shaoqi Zhou Weihao Ma Guotao Huang Bin Xu | 2011 | Desalination2011，，： | 2 |
| 13 | Optimization and analysis of winglet configuration for solar aircraft显示文摘Installing winglets can notably improve the aerodynamic performance of solar aircraft.This paper proposes a multi-constraints optimization method of winglets for solar aircraft,aiming to enhance the corresponding uninterrupted cruising capability.An optimization objective function is formed and is separately studied in aerodynamic and structural terms.Qualitative analysis shows that the winglet design parameters are restricted by four special constraints(geometry,aerodynamics,energy and stability)of solar aircraft.The optimization process is constructed on the basis of a multi-island genetic algorithm,and carried out for a 15 m wingspan solar aircraft.Although the designed winglet is not as good as the traditional winglet in terms of drag and structural weight,the designed winglet provides a better 24 h cruising capability.The sensitivity between the objective function and the design parameters is investigated,and the winglet effects vary with respect to the wing aspect ratio(AR=10,15,19.6).The effect of the constraints is analysed quantitatively,and some basic laws are obtained.Moreover,the feasible design region and the possible optimal design parameters of winglets for different wing configurations are explored.The calculation results show that when the aspect ratio exceeds a certain value,the winglets will not benefit the aircraft. | Liang ZHANG Dongli MA Muqing YANG Shaoqi WANG | 2020 | Chinese Journal of Aeronautics2020，33，12： | 2 |
| 14 | Effects of heavy metals on planting watercress in kailyard soil amended by adding compost of sewage sludge 显示文摘 | ZHOU Shaoqi LU Weidong ZHOU Xiao | 2010 | Process Safety and Environmental Protection2010，88，4： | 1 |
| 15 | INT-dehydrogenase activity test for assessing anaerobic biodegradability of organic compounds显示文摘 | Yang Hongwei Jiang Zhanpeng Shi Shaoqi | 2002 | Ecotoxicology and Environmental Safety2002，53，： | 1 |
| 16 | Removal ofhumic substances from Landfill Leachate by Fenton oxidation and coagulation 显示文摘 | Wu Yanyu Zhou Shaoqi Qin Fanghui | 2010 | Process Safety and Environmental Protection2010，88，4： | 1 |
| 17 | Anaerobic biodegradability of aliphatic compounds and their quantitative structure biodegradability relationship显示文摘 | Yang Hongwei Jiang Zhanpeng Shi Shaoqi | 2004 | Science of the Total Environment2004，322，： | 1 |
| 18 | Constructing disease-specific gene networks using pair-wise releyance metric : Application to co- lon cancer identifies interleukin8,desmin and enolase 1 as the cen tral elements显示文摘 | Wei Jiang Xia Li Shaoqi Rao | 2008 | BMC Systems Biology2008，2，： | 1 |
| 19 | Effect of different types of electron acceptors on the anoxic phosphorus uptake activity of denitrifying phosphorus removing bacteria 显示文摘 | Zhou Shaoqi Zhang Xiaojie Feng Linyu | 2010 | Bioresource Technology2010，101，6： | 1 |
| 20 | The biological treatment of landfill leachate using a simultaneous aerobic and anaerobic (SAA) bio-reactor system显示文摘 | Yang Zhiquan Zhou Shaoqi | 2008 | Chemosphere2008，72，11： | 1 |
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