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| 1 | Comparison of Leptosphaeria biglobosa-induced and chemically induced systemic resistance to L.maculans in Brassica napus显示文摘Brassica napus(cv.Madrigal)seedlings pre-treated with ascospores of Leptosphaeria biglobosa or foliar sprays of either acibenzolar-S-methyl(ASM)or menadione sodium bisulphite(MSB)were chal- lenge inoculated with L.maculans ascospores and assessed for phoma leaf spot development and tissue morphology and gene expression responses to infection.Rates of increase in phoma leaf spot area 8―21 d after challenge inoculation were significantly greater on water pre-treated plants than on plants pre-treated with L.biglobosa,ASM or MSB on both pre-treated leaves(local effect)and younger leaves without pre-treatment(systemic effect).Ninety-six h after challenge inoculation,the invasive hyphae of L.maculans were encircled by rings of necrotic mesophyll cells on leaves pre-treated with L. biglobosa,ASM or MSB but not those pre-treated with water.Quantification of transcript levels of genes commonly used as markers of the major defence signalling pathways(PDF1.2,PR-1,NPR1,APX, CHB4)0–96 h after L.maculans challenge inoculation showed expression patterns indicating prefer- ential activation of the jasmonate/ethylene pathway and involved induction of NPR1 locally and sys- temically in leaves of plants pre-treated with L.biglobosa ascospores. | LIU ShengYi LIU RenHu Akinwunmi O. LATUNDE-DADA Hans J. COOLS Simon J. FOSTER HUANG YongJu Bruce D. L. FITT | 2007 | Chinese Science Bulletin2007，52，8： | 4 |
| 2 | The Role of Dihydroresveratrol in Enhancing the Synergistic Effect of Ligilactobacillus salivarius Liol and Resveratrol in Ameliorating Colitis in Mice显示文摘Currently approved therapeutical strategies for inflammatory bowel diseases(IBD)suffer from variable efficacy and association with risk of serious side effects.Therefore,efforts have been made in searching for alternative therapeutics strategies utilizing gut microbiota manipulation.In this study,we show that the probiotic strain Ligilactobacillus salivarius Li01(Li01)and the phytochemical prebiotic resveratrol(RSV)have synergistic effect in ameliorating colitis in mice.Oral coadministration of Li01(109 CFU/d)and RSV(1.5 g/kg/d)promoted restoration of various inflammatory injuries and gut microbiota composition,exhibiting a favorable anti-inflammatory effect in DSS-induced colitis mice.The combination treatment was associated with reductions in the levels of proinflammatory cytokines IL-1βand IL-6 and increases in the levels of the anti-inflammatory cytokine IL-17A in mouse serum.Moreover,the combination treatment was found to alter the composition and metabolism of the gut microbiota,especially influencing the production of short chain fatty acids and anti-inflammatory related molecules.The mechanism underlying the improved anti-inflammatory effect from the RSV and Li01 combination treatment was found to be associated with the environmental sensor mammalian aryl hydrocarbon receptor(AHR)and tryptophan metabolism pathway.Administration of RSV in combination with Li01 in different mouse model led to enhanced conversion of RSV into metabolites,including dihydroresveratrol(DHR),resveratrol-sulfate,and resveratrol-glucuronide.DHR was found to be the dominant metabolite of RSV in conventional and colitis mice.An increased DHR/RSV ratio was confirmed to activate AHR and contribute to an enhanced anti-inflammatory effect.DHR is considered as a potential AHR ligand.The DHR/RSV ratio also affected the serotonin pathway by controlling the expression of Tph1,SERT,and 5-HT7R leading to amelioration of colitis in mice.Our data suggest that treatment with a combination of Li01 and RSV has potential as a therapeutic strategy for IBD;further investigation of this combination in clinical settings is warranted. | Yiqiu Fei Shuobo Zhang Shengyi Han Bo Qiu Yanmeng Lu Weixing Huang Fang Li Deying Chen Bjorn Berglund Hang Xiao Lanjuan Li Mingfei Yao | 2022 | Research2022，，4： | 1 |
| 3 | Overexpres- sion of Brassica napus MPK4 enhances resistance to Scle- rotinia sclerotiorum in oilseed rape 显示文摘 | Wang Zheng Mao Han Liu Shengyi | 2009 | Molecular Plant - Microbe Interactions2009，22，3： | 1 |
| 4 | Supramolecular control over LCST behavior of hybrid macrocyclic system based on pillar[5]arene and crown ether显示文摘A hybrid system containing a pillar[5]arene unit and ten crown ether moieties was developed.The LCST behavior and thermo-responsive ness were successfully introduced into this pillar[5]arene-crown ether system.Both host-guest interactions and salting-out effect displayed great effects in realizing the supramolecular control over LCST properties and the rmo-re sponsiveness.Compa red with the individual macrocycles,this hybrid macrocycle system dramatically amplified the supramolecular control effect over LCST behavior. | Yan Deng Xing Li Chengyou Han Shengyi Dong | 2020 | Chinese Chemical Letters2020，31，12： | 0 |
| 5 | Lipid biomarker composition in surface sediments from the Carlsberg Ridge near the Tianxiu Hydrothermal Field显示文摘Hydrothermal venting has a profound effect on the chemical and biological properties of local and distal seawater and sediments. In this study, lipid biomarkers were analyzed to examine the potential influence of hydrothermal activity on the fate of organic matter(OM) in surface sediments around Tianxiu Hydrothermal Field in the Carlsberg Ridge(CR), Northwest Indian Ocean. By comparing the biomarker distributions of the samples with that of other typical hydrothermal sediments in the mid ocean ridge, it is shown that the location of the samples is not affected by the hydrothermal activity. The relatively low abundances of terrestrial n-alkyl lipids and riverine1,15-C_(32) diol suggested a minor contribution of terrigenous OM to the study area. The bacteria contributed predominantly to sedimentary marine OM;however, other marine source organisms, e.g., eukaryotes(i.e.,phytoplankton and fungi) could not be completely neglected. The marine-originated biomarkers showed significantly variable distributions between the two sediments, suggesting different dynamic physical and biogeochemical processes controlling the fate of marine OM. This study identified various diagnostic biomarkers(5,5-diethyl alkanes, diols and β-OH FAs), which may have significant environmental implications for future works in this region. | Shengyi Mao Hongxiang Guan Lihua Liu Xiqiu Han Xueping Chen Juan Yu Yongge Sun Yejian Wang | 2021 | Acta Oceanologica Sinica2021，40，8： | 0 |
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