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| 1 | Comparison of microstructure and mechanical properties of titanium/ steel composite plates by two manufacturing processes显示文摘 | Xuan Yang Chang-gen Shi Yu-heng Ge Md Nahid Hasan Sabuj | 2018 | Journal of Iron and Steel Research(International)2018，25，3： | 7 |
| 2 | Spatial and temporal regulation of collagenases-3, -4,and stromelysin -3 implicates distinct functions in apoptosis and tissue remodeling during frog metamorphosis显示文摘Matrix metalloproteinases (MMPs) are a family of extracellular proteases capable of degrading various proteinaceous components of the extracellular matrix (ECM).They have been implicated to play important roles in a number of developmental and pathological processes, such as tumor metastasis and inflammation. Relatively few studies have been carried out to investigate the function of MMPs during postembryonic organ-development. Using Xenopus laevis development as a model system, we demonstrate here that three MMPs, stromelysin-3 (ST3),collagenases-3 (Col3), and Col4, have distinct spatial and temporal expression profiles during metamorphosis as the tadpole transforms into a frog. In situ hybridizations reveal a tight, but distinct, association of individual MMPs with tissue remodeling in the tail and intestine during metamorphosis. In particular, ST3 expression is strongly correlated with apoptosis in both organs as demonstrated by analyses of serial sections with in situ hybridization for ST3 mRNA and TUNEL (terminal deoxyribonucleotidyl transferase-mediated dUTP-biotin nick end labeling) for apoptosis, respectively. On the other hand, Col3 and Col4 MMPs in Xenopus laevis development are present in regions where extensive connective tissue remodeling take place. These results indicate that ST3 is likely to play a role in ECM-remodeling that facilitateapoptotic tissue remodeling or resorption while Col3 and Col4 appear to participate in connective tissue degradation during development. | DAMJANOVSKI SASHKO ATSUKO ISHIZUYAOKA YUN-BO SHI (Laboratory of Molecular Embryology, Building 18T, Rm. 106, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA)(Department Of Histology and | 1999 | Cell Research1999，9，2： | 3 |
| 3 | Magnitude of modulation of gene expression in aneuploid maize depends on the extent of genomic imbalance显示文摘Aneuploidy has profound effects on an organism,typically more so than polyploidy,and the basis of this contrast is not fully understood.A dosage series of the maize long arm of chromosome 1(1L)was used to compa re relative global gene expression in diffe rent types and degrees of aneuploidy to gain insights into how the magnitude of genomic imbalance as well as hypoploidy affects global gene expression.While previously available methods require a selective examination of specific genes,RNA sequencing provides a whole-genome view of gene expression in aneuploids.Most studies of global aneuploidy effects have concentrated on individual types of aneuploids because multiple dose aneuploidies of the same genomic region are difficult to produce in most model genetic organisms.The genetic toolkit of maize allows the examination of multiple ploidies and 1-4 doses of chromosome arms.Thus,a detailed examination of expression changes both on the varied chromosome arms and elsewhere in the genome is possible,in both hypoploids and hyperploids,compared with euploid controls.Previous studies observed the inverse trans effect,in which genes not varied in DNA dosage were expressed in a negative relationship to the varied chromosomal region.This response was also the major type of changes found globally in this study.Many genes varied in dosage showed proportional expression changes,though some were seen to be partly or fully dosage compensated.It was also found that the effects of aneuploidy were progressive,with more severe aneuploids producing effects of greater magnitude. | Adam F·Johnson Jie Hou Hua Yang Xiaowen Shi Chen Chen Md Soliman Islam Tieming Ji Jianlin Cheng James A·Birchler | 2020 | Journal of Genetics and Genomics2020，47，2： | 3 |
| 4 | Surgical Treatment of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus显示文摘 | Jie Shi MD Eric C. H. Lai MBChB MRCS(Ed) FRACS Nan Li MD Wei-Xing Guo MD Jie Xue MD Wan Yee Lau MD FRCS FACS FRACS(Hon) Meng-Chao Wu MD Shu-Qun Cheng MD | 2010 | Annals of Surgical Oncology2010，，8： | 2 |
| 5 | A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for T2N0 Rectal Cancer: Preliminary Results of the ACOSOG Z6041 Trial显示文摘 | Julio Garcia-Aguilar MD PhD Qian Shi PhD Charles R. Thomas MD Emily Chan MD PhD Peter Cataldo MD Jorge Marcet MD David Medich MD Alessio Pigazzi MD Samuel Oommen MD Mitchell C. Posner MD | 2012 | Annals of Surgical Oncology2012，，2： | 2 |
| 6 | A Comparative Study of Antiviral Therapy After Resection of Hepatocellular Carcinoma in the Immune-Active Phase of Hepatitis B Virus Infection显示文摘 | Nan Li MD Eric C. H. Lai MBChB MRCS(Ed) FRACS Jie Shi MD Wei-Xing Guo MD Jie Xue MD Bing Huang MD Wan-Yee Lau MD FRCS FACS FRACS(Hon) Meng-Chao Wu MD Shu-Qun Cheng MD | 2010 | Annals of Surgical Oncology2010，，1： | 2 |
| 7 | Regulation of P450c17 expres-sion in the early embryo depends on GATA factors显示文摘 | Shi Y Schonemann MD Mellon SH | 2009 | Endocrinolo-gy2009，150，2： | 1 |
| 8 | Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human 显示文摘 | Shi TJ Xiang Q Zhang MD | 2012 | Mol Pain2012，8，： | 1 |
| 9 | Semiconstrained Primary and Revision Total Elbow Arthroplasty with Use of the CoonradMorrey Prosthesis显示文摘 | Shi LL MD Zurakowski D Jones DG | 2007 | J Bone Joint Surg Am2007，89，7： | 1 |
| 10 | Characterization of the 3a protein of SARS-assoeiated coronavirus in infected vero E6 cells and SARS patients显示文摘 | Zeng R Yang RF Shi MD | 2004 | J Mol Biol2004，341，1： | 1 |
| 11 | Template-imprinting nanostructured surfaces for protein recognition显示文摘 | Shi H Tsai WB Garrison MD Fenari S Ratner BD | 1999 | Nature1999，396，6728： | 1 |
| 12 | Purification and preliminary crystallographic analysis of a Penicillium expansum lipase 显示文摘 | Bian CB Yuan C Lin L Lin JH Shi XL Ye XM Huang ZX Huang MD | 2005 | Biochim Biophys Acta2005，1752，： | 1 |
| 13 | Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition 显示文摘 | Goudar RK Shi Q Hjelmeland MD | 2005 | Mol Cancer Ther2005，4，1： | 1 |
| 14 | a-To- marine suppi'esses invasion and migration of human non-small cell lung cancer NCI-H460 cells through in- activating FAK/PI3K/Akt signaling pathway and re- ducing binding activity of NF-κB显示文摘 | SHIEH J M CHENGT H SHI MD | 2011 | Cell Biochem Biophys2011，60，： | 1 |
| 15 | A-tomatine suppresses invasion and migration of human non-small cell lung cancer NCI-H460 cells through inactivating FAK/PI3K/Akt signaling pathway and reducing binding activity of NF-jB 显示文摘 | Shieh JM Cheng TH Shi MD | 2011 | Cell Biochem Biophys2011，60，1： | 1 |
| 16 | TGF/BMP signaling in cartilage and bone cells显示文摘 | Wan Mei MD PhD Shi Xingming PhD Cao Xu PhD | 2002 | Current Opinion in Orthopaedics2002，13，5： | 1 |
| 17 | Inhibition of cell cycle progression in human colorectal carcinoma LOVo cells by andrographolide 显示文摘 | Shi MD Lin HH Lee YC | 2008 | Chem Biol Interact2008，174，： | 1 |
| 18 | Advanced glyca- tion end product (AGE) modified proteins in tears of diabetic patients 显示文摘 | Zhao Z Liu J Shi B He S Yao X Willcox MD | 2010 | Mol Vis2010，16，： | 1 |
| 19 | ENaC regulation by proteases and shear stress 显示文摘 | Shi S Carattino MD Hughey RP | 2013 | CUrT Mol Pharmacol2013，6，： | 1 |
| 20 | Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisplatin via enhancing apoptosis pathways in vitro and in vivo显示文摘 | Lin HH Shi MD Tseng HC | 2014 | Toxicol Sci2014，139，1： | 1 |
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