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| 1 | PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix显示文摘Biofilms 是在细胞外的矩阵嵌入的微生物的联系表面的社区。Exopolysaccharide 是在维持 biofilm 建筑学并且保护居民 biofilm 细菌免受抗菌剂和主人免疫者攻击的伤害的细胞外的矩阵的一个批评部件。然而,指向矩阵 exopolysaccharides 的自我生产的因素,仍然糟糕被理解。这里,我们显示出那 PslG,在 Pseudomonas aeruginosa 涉及关键 biofilm 矩阵 exopolysaccharide Psl 的合成的蛋白质,阻止 biofilm 形成并且拆卸存在在外长地供应的在 nanomolar 集中的分钟以内的 biofilms。PslG 的水晶结构显示 endoglycosidase 的典型特征。PslG 主要破坏 Psl 矩阵从 biofilms 驱散细菌。PslG 处理显著地提高 biofilm 敏感到抗菌素和巨噬细胞房间,导致在一只老鼠的改进 biofilm 清理植入感染模型。而且, PslG 对大量 Pseudomonas 种类显示出 biofilm 抑制和拆卸活动,显示它在与 biofilm 相关的复杂并发症作斗争的大潜力。 | Shan Yu Tiantian Su Huijun Wu Shiheng Liu Di Wang Tianhu Zhao Zengjun Jin Wenbin Du Mei-Jun Zhu Song Lin Chua Liang Yang Deyu Zhu Lichuan Gu Luyan Z Ma | 2015 | Cell Research2015，25，12： | 13 |
| 2 | Sequence and epitope analysis of surface proteins of avian influenza H5N1 viruses from Asian patients显示文摘Increasing cases of human infections with the high pathogenic avian influenza virus H5N1 have raised great concern on potential human flu pandemics caused by H5N1. The two viral surface glycoproteins, the hemagglutinin (HA) and the neuraminidase (NA) proteins, are major antigens o H5N1. Introducing new mutations on these two pro teins is the major strategy used by H5N1 to expand host range and to avoid the recognition of host im mune systems. We analyzed the two surface proteins of H5N1 from Asian human patients and identified many new mutation sites, including a few that were unique to certain lethal strains. We also analyzed the distribution of mutations on different epitopes of the two surface proteins. A receptor-binding site tha might involve in the determination of host specificity of H5N1 was also found. Results reported here pro vided information for better understanding of the evolution trend of H5N1 genome in human. | LI Guanglin TAO Shiheng WANG Xiujie | 2006 | Chinese Science Bulletin2006，51，20： | 6 |
| 3 | MgO(001) barrier based magnetic tunnel junctions and their device applications显示文摘Spintronics has received a great attention and significant interest within the past decades,and provided considerable and remarked applications in industry and electronic information etc.In spintronics,the MgO based magnetic tunnel junction(MTJ) is an important research advancement because of its physical properties and excellent performance,such as the high TMR ratio in MgO based MTJs.We present an overview of more than a decade development in MgO based MTJs.The review contains three main sections.(1) Research of several types of MgO based MTJs,including single-crystal MgO barrier based-MTJs,double barrier MTJs,MgO based MTJs with interlayer,novel electrode material MTJs based on MgO,novel barrier based MTJs,novel barrier MTJs based on MgO,and perpendicular MTJs.(2) Some typical physical effects in MgO based MTJs,which include six observed physical effects in MgO based MTJs,namely spin transfer torque(STT) effect,Coulomb blockade magnetoresistance(CBMR) effect,oscillatory magnetoresistance,quantum-well resonance tunneling effect,electric field assisted magnetization switching effect,and spincaloric effect.(3) In the last section,a brief introduction of some important device applications of MgO based MTJs,such as GMR & TMR read heads and magneto-sensitive sensors,both field and current switching MRAM,spin nano oscillators,and spin logic devices,have been provided. | HAN XiuFeng ALI Syed Shahbaz LIANG ShiHeng | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，1： | 4 |
| 4 | The origin of Mosuo people as revealed by mtDNA and Y chromosome variation显示文摘The Mosuo, living in the Lugu Lake area in northwest Yunnan Province, China, is the only matriarchal population in China. The Mosuo was officially identified as Naxi nationality although its relationship with Naxi remains controversial. We studied the genetic relationship between the Mosuo and five other ethnic groups currently residing in northwest Yunnan, i.e. Naxi, Tibetan, Bai, Yi and Pumi, by typing the genetic variations in mtDNA HVS1 and 21 Y chromosome markers (13 SNPs & 8 STR markers). We showed that the maternal lineages of the Mosuo bear the strongest resemblance with those found in Naxi while its paternal lineages are more similar to those that are prevalent in Yunnan Tibetan. The marked difference between paternal and maternal lineages may be attributable to the genetic history, matriarchal structure, and visiting marriage. | WEN Bo, SHI Hong, REN Ling, XI Huifeng, LI Kaiyuan, ZHANG Wenyi, SU Bing, SI Shiheng, JIN Li & XIAO ChunjieJoined Laboratory of Human Population Genetics of Yunnan University and Fudan University, Kunming 650091, China Key Laboratory of Bioresources Conservation and Utilization & Human Genetics Center of Yunnan University, Kunming 650091, China National Key Laboratory of Genetic Engineering & Center for Anthropological Studies, School of Life Sciences, Fudan University, Shanghai 200433, China Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650031, China Center for Genome Information, Department of Environmental Health, University of Cincinnati, Cincinnati 45267, USA The Central Hospital of Ninglang County, Ninglang 674300, China | 2004 | Science China(Life Sciences)2004，47，1： | 3 |
| 5 | Argon Plasma-Induced Graft Polymerization of PEGMA on Chitosan Membrane Surface for Cell Adhesion Improvement显示文摘For its biocompatibility and biodegradability,chitosan has had considerable attention for biomedical applications in recent years.In this paper,polymerization of poly(ethylene glycol)methyl ether methacrylate(PEGMA)was grafted onto chitosan membrane surface through argon plasma-induced graft polymerization.The surface properties after modification were characterized by contact angle measurement,X-ray photoelectron spectroscopy(XPS)and atomic force microscopy(AFM),respectively.The results indicated that PEGMA can be grafted successfully onto chitosan membrane surface.The surface hydrophilicity and free energy were improved and the surface roughness increased after modification.The adhesion of a human corneal epithelial cell(HCEC)on chitosan membrane surface was enhanced due to improvement of surface free energy and roughness. | YIN Shiheng REN Li WANG Yingjun | 2013 | Plasma Science and Technology2013，15，10： | 2 |
| 6 | Prediction of sorghum miRNAs and their targets with computational methods显示文摘microRNAs 是 21-nt 的一个班在 post-transcriptional 起关键作用的长、非编码、最新识别的 RNA 基因规定。他们的目标涉及各种各样的生物过程,包括开发,新陈代谢,和压力反应。尽管很多 miRNAs 在许多种类被报导了,在蜀黍的 miRNAs 的报告是有限的。基于 genomic 调查顺序(GSS ) 和 microRNA (miRNA ) 使用相同搜索第二等的结构, 17 新 miRNAs 的一个总数在这个工作被识别。他们被发现在 11 个 miRNA 家庭之中不均匀的分布式。一些 miRNA 基因在多重地点并且在超过一 genomic 上下文被发现。大多数 miRNAs 在一样的王国以内被保存,但是我们在蜀黍发现 sbi-miR127 和 sbi-miR466 与 H 显示出保存。现代人并且 M。musculus 分别地。经由联机软件 miRU 的那些 17 新 miRNAs 的分析证明他们可能调整 64 目标基因,其大多数涉及 RNA 处理,新陈代谢,房间周期,蛋白质降级,压力反应和交通。11 个 miRNA 家庭中的至少 7 个指向在新陈代谢和压力反应是必要的蛋白质,包括 NADPH 细胞色素 P450 reductase, nucleoside diphosphate kinase 和 superoxide dismutase,建议 miRNAs 起在生物过程的一个必要作用。 | DU JiangFeng WU YongJun FANG XiaoFeng CAO JunXia ZHAO Liang TAO ShiHeng | 2010 | Chinese Science Bulletin2010，55，13： | 2 |
| 7 | Surface characteristics and biocompatibility of sandblasted and acid‐etched titanium surface modified by ultraviolet irradiation: An in vitro study显示文摘 | Shaobing Li Jia Ni Xiangning Liu Xueyang Zhang Shiheng Yin Mingdeng Rong Zehong Guo Lei Zhou | 2012 | J Biomed Mater Res2012，，6： | 1 |
| 8 | Coupled fixed points for mixed monotone condensing operators and an existencetheorem of the solution for a class of functional equations arising in dynamic programming显示文摘 | MA Yihai | 1991 | J Math Anal Appl1991，160，： | 1 |
| 9 | On the existence and uniqueness theorems of the systems of mixed monotone operator equations with applications显示文摘 | GUO Weipin | 1993 | Applied mathematics a Journal of Chinese Universities1993，8，1： | 1 |
| 10 | Characterization and biocompatibility of nanohybrid scaffold prepared via in situ crystallization of hydroxyapatite in chitosan matrix显示文摘 | Jingdi Chen Kaihui Nan Shiheng Yin | 2010 | Colloids and Surfaces B:Biointerfaces2010，81，： | 1 |
| 11 | Leaching Machanism of the Spodumene by Sulfuric Acid Process 显示文摘 | Xiao Mingshun Wang Shiheng Zhang Qinfang | 1997 | Rare Metal1997，16，1： | 1 |
| 12 | Analyst following and forecast accuracy after mandated IFRS adoptions 显示文摘 | Tan Hongping Wang Shiheng Welker M | 2011 | Jour- nal of Accounting Research2011，49，： | 1 |
| 13 | A population genetics model of linkage disequilibrium in admixed populations显示文摘Understanding linkage disequilibrium (LD) created in admixed population and the rate of decay in the disequilibrium over evolution is an important subject in population genetics theory and in disease gene mapping in human populations. The present study represents the theoretical investigation of effects of gene frequencies, levels of LD and admixture proportions of donor populations on the evolutionary dynamics of the LD of the admixed population. We examined the conditions under which the admixed population reached linkage equilibrium or the peak level of the LD. The study reveals the inappropriateness in approximating the dynamics of the LD generated by population admixture by the commonly used formula in literature. An appropriate equation for the dynamics isproposed. The distinct feature of the newly suggested formula is that the value of the nonlinear component of the LD remains constant in the first generation of the population evolution. Comparison between the predicted disequilibrium dynamics | Shiheng Tao Rongmei Zhang Jianhua Chu Xiaoming Liu Liping Du Qingyuan Qi Zewei Luo | 2001 | Chinese Science Bulletin2001，46，3： | 1 |
| 14 | Timing Equity Issuance in Response to Information Asymmetry Arising from IFRS Adoption in Australia and Europe, Journal of Accounting Research显示文摘 | Shiheng Wang and Michael Welker | 2011 | 49(1): 257-3072011，49，1： | 1 |
| 15 | Theta pairs and the structure of finite groups显示文摘 | Li Xianhua and Li Shiheng | 2004 | Siberian Mathematical Journal2004，45，3： | 1 |
| 16 | Finite groups with some subgroups semi eover-avoiding显示文摘 | LI Shiheng LIANG Dengfeng | 2006 | J Suzhou Universi- ty2006，22，1： | 1 |
| 17 | Controllable printing of large-scale compact perovskite films for flexible photodetectors显示文摘Perovskite materials are promising candidates for the next generation of wearable optoelectronics.However,due to uncontrolled crystallization and the natural brittle property of crystals,it remains a great challenge to fabricate large-scale compact and tough perovskite film.Here we report a facile method to print large-scale perovskite films with high quality for flexible photodetectors.By introducing a soluble polyethylene oxide(PEO)layer during the inkjet printing process,the nucleation and crystal growth of perovskite is well controlled.Perovskite films can be easily printed in large scale and patterned in high resolution.Moreover,this method can be extended to various kinds of perovskite materials,such as MAPbb(MA=methylammonium),MA_(3)Sb_(2)l_(9),and(BA)_(2)PbBr_(4)(BA=benzylammonium).The printed perovskite films show high quality and excellent mechanical performance.The photodetectors based on the MAPbBr3 perovskite films show a responsivity up to -1,036 mAA/V and maintain over 96.8%of the initial photocurrent after 15,000 consecutive bending cycles.This strategy provides a facile approach to prepare large-scale flexible perovskite films.It opens up new opportunities for the fabrication of diverse wearable optoelectronic devices. | Zhenkun Gu Ying Wang Shiheng Wang Ting Zhang Rudai Zhao Xiaotian Hu Zhandong Huang Meng Su Qun Xu Lihong Li Yiqiang Zhang Yanlin Song | 2022 | Nano Research2022，15，2： | 1 |
| 18 | Finite groups with some subgroups semi-cover-avoiding显示文摘 | LI Shiheng LIANG Dengfeng | 2006 | J Suzhou University2006，22，1： | 1 |
| 19 | Finite groups with some subgroups semi cover-avoiding显示文摘 | LI Shiheng LIANG Dengfeng | 2006 | J Suzhou University2006，22，1： | 1 |
| 20 | A review of the literature on randomized controlled trials of acupuncture and moxibustion in the treatment of chronic prostatitis/chronic pelvic-pain syndrome within 2016-2021显示文摘Chronic prostatitis(CP)/chronic pelvic-pain syndrome(CPPS)is a common urinary-system disease with a high incidence in young and middle-aged men,seriously affecting patients'ability to work and their quality of life(Qo L).Western medicine(WM)has some limitations in treating CP/CPPS.Acupuncture is an ancient Chinese medical method that is commonly used to treat this condition and has a relatively good effect on it.Many randomized controlled trials(RCTs)on this subject have been published.For this study,we searched the China National Knowledge Infrastructure(CNKI),Chinese Science and Technology Periodical(VIP),Wanfang,Sino Med,and Pub Med databases for RCTs on acupuncture treatment of CP/CPPS in the last 5 years(2016/01/01-2021/12/01).In addition,we conducted analysis and research,aiming to summarize acupuncture treatment in CP/CPPS RCTs and the clinical efficacy,with the goal of providing clinical reference.A total of 466 related documents were retrieved in the search,and 62 articles were retained after screening.We obtained RCT information on acupuncture treatment of CP/CPPS.The results showed that several relevant clinical studies have been performed over the last 5 years and that acupuncture and moxibustion have better curative effect on CP/CPPS than WM.Due to the small number of included studies,more experimental evidence is needed to verify the clinical efficacy of acupuncture. | Shiheng Wang Peijie Qin Fengxia Zhang Jianfeng Liu | 2022 | Journal of Traditional Chinese Medical Sciences2022，9，3： | 1 |
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