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77篇 您的检索式:作者名="Shinzawa"
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1RANKL-RANK interaction in immune regulatory systems显示文摘The interaction between the receptor activator of NF-κB ligand(RANKL)and its receptor RANK plays a critical role in the development and function of diverse tissues.This review summarizes the studies regarding the functions of RANKL signaling in immune regulatory systems.Previous in vitro and in vivo studies have indicated that the RANKL signal promotes the survival of dendritic cells(DCs),thereby activating the immune response.In addition,RANKL signaling to DCs in the body surface barriers controls self-tolerance and oral-tolerance through regulatory T cell functions.In addition to regulating DC functions,the RANKL and RANK interaction is critical for the development and organization of several lymphoid organs.The RANKL signal initiates the formation of clusters of lymphoid tissue inducer cells,which is crucial for lymph node organogenesis.Moreover,the RANKL-RANK interaction controls the differentiation of M cells,specialized epithelial cells in mucosal tissues,that take up and transcytose antigen particles to control the immune response to pathogens or commensal bacterium.The development of epithelial cells localized in the thymic medulla(m TECs)is also regulated by the RANKL-RANK signal.Given that the unique property ofm TECs to express a wide variety of tissue-specific selfantigens is critical for the elimination of self-antigen reactive T cells in the thymus,the RANKL-RANK interaction contributes to the suppression of autoimmunity.Future studies on the roles of the RANKL-RANK system in immune regulatory functions would be informative for the development and application of inhibitors of RANKL signaling for disease treatment.Taishin Akiyama Miho Shinzawa Nobuko Akiyama 2012World Journal of Orthopedics2012,3,9:5
2Amyotrophic cervical myelopathy in adolescence显示文摘TOMA S SHINZAWA Z 1995Neurol Neurosuerg Psychiatry1995,58,:1
3Accelerated weathering-induced degradation of Poly(Lactic acid) fiber studied by near-infrared (NIR) hyperspectral imaging显示文摘Shinzawa H Nishida M Tanaka T 0,,04:1
4Perturbation-correlation moving-window two-dimensional correlation spectroscopy 显示文摘MORITA S SHINZAWA H NODA I 2006Applied Spectroscopy2006,60,:1
5Home lactulose enema: prevention of hepatic encephalopathy at home 显示文摘Saito T Shinzawa H Watanabe H 2002Gastroenterol2002,37,1:1
6Home lactulose enema: prevention of hepatic encephalopathy at home显示文摘Saito T Shinzawa H Watanabe H 2002J Gastroenterol2002,37,1:1
7Neuroaxonal dystrophy in calci- um-independent phospholipase A213 deficiency results from insufficient remodeling and degeneration of mito- chondrial and presynaptic membranes 显示文摘Beck G SY Shinzawa K 2011J Neurosci2011,31,11:1
8An evalua- tion of hepatic ultrasound speed in injury models in rats:correlation with tissue constituents 显示文摘MATSUHASHI T YAMADA N SHINZAWA H 1996J Ultrasound Med1996,5,8:1
9Mutations of the X region of hepatitis B virus and their clinical implications显示文摘Uchida T Saitoh T Shinzawa H 1997Pathol Int1997,47,:1
10Mutation of the X region of hepatitis B virus and their clinical implications 显示文摘Uchida T Saitoh T Shinzawa H 1997Pathol Int1997,47,4:1
11Rheo-optical near-infrared (NIR) spectroscopy study of low-density polyethylene (LDPE) in conjunction with projection two-dimensional (2D) correlation analysis显示文摘Hideyuki Shinzawa Wataru Kanematsu Isao Noda 2014Vibrational Spectroscopy2014,,:1
12Pressure-induced variation of cellulose tablet studied by two-dimensional (2D) near-infi-ared (NIR) correlation spectroscopy in conjunction with projection pretreatrnent 显示文摘SHINZAWA H AWA K NODA I 2013Vibrational Spectroscopy2013,65,:1
13The immunohistological study of alpha - fetopro-tein on carcinoma of digestive organs 显示文摘Shinzawa H 1980Nippon Shokakibyo Gakkai Zasshi1980,77,8:1
14Value of laparoscopic microwave coagulation therapy for hepatocellular carcinoma in relation to tumor size and location 显示文摘Abe T Shinzawa H Wakabayashi H 2000Endoscopy2000,32,:1
15Pathogenesis of lipid metabolism disorder in hepatitis C: Polyunsaturated fatty acids counteract lipid alterations induced by the core protein显示文摘Hideyuki Miyoshi Kyoji Moriya Takeya Tsutsumi Seiko Shinzawa Hajime Fujie Yoshizumi Shintani Hidetake Fujinaga Koji Goto Toru Todoroki Tetsuro Suzuki Tatsuo Miyamura Yoshiharu Matsuura Hiroshi Yotsuyanagi Kazuhiko Koike 2010Journal of Hepatology2010,,3:1
16Growth inhibition and apoptosis of gastric cancer cell lines by Anemarrhena asphodeloides Bunge显示文摘Yoshio Takeda Hitoshi Togashi Taku Matsuo Haruhide Shinzawa Yumiko Takeda Tsuneo Takahashi 2001Journal of Gastroenterology2001,,2:1
17Self-modeling curve resolution (SMCR) analysis of near-infrared (NIR) imaging data of pharmaceutical tablets 显示文摘Awa K Okumura T Shinzawa H 2008Analytica Chimica Acta2008,619,1:1
18Non-destructive and rapid analysis of chemical compositions in Thai steamed pork sausages by near-infrared spectroscopy 显示文摘Pitiporn Ritthiruangdej Ronnarit Ritthiron Hideyuki Shinzawa 2011Food Chemistry2011,129,2:1
19Neuroaxonal dystrophy in calcium-independent phospholipase A2beta deficiency results from in- sufficient remodeling and degeneration of mitochondrial and presynap- tic membranes显示文摘Beck G Sugiura Y Shinzawa K 2011J Neurosci2011,31,11:1
20Use of short-period microtrcmors for VS profiling显示文摘KOKKMIMATSU K SHINZAWA k KUWAYAMA S 1992Journal of Geotechnical Engineering1992,118,10:1
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