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    题名 作者 年代 出处 被引量
1散裂中子源与先进核能系统显示文摘散裂中子源的应用日益受到人们的重视。本报告仅对散裂中子源的历史、物理基础、对加速器要求、靶系统及其应用于先进核能系统作一般介绍。LI SHOUNAN (China Institute of Atomic Energy) 1998核科学与工程1998,18,1:5
2关于先进核能系统的嬗变能力显示文摘就中子经济性对不同类型先进核能系统的嬗变能力进行初步分析和比较。LI SHOUNAN (China Institute of Atomic Energy) 1998核科学与工程1998,18,3:4
3Gene therapy by myoblast-mediated gene transfer显示文摘 Shounan Y 1995Somatic Gene Therapy1995,8,:1
4Transplantation of Xenogeneic Islets: Are We There Yet?显示文摘Philip J. O’Connell Peter J. Cowan Wayne J. Hawthorne Shounan Yi Andrew M. Lew 2013Current Diabetes Reports2013,,5:1
5Adoptive transfer with in vitro expanded human regulatory T cells protects against porcine islet xenograft rejection via interleukin- 10 in humanized mice 显示文摘Shounan Y Ming J Jingjing W 2012Diabetes2012,61,5:1
6Right hepatectomy with preservation of segment VI: Seven cases of preliminary experience显示文摘Background:Surgical treatment of tumors near the center of the liver is challenging.Right hemihepatic or triple resection is considered the preferred approach,but it is associated with a high mortality rate due to postoperative liver failure.Therefore,attempts should be made to preserve liver parenchyma to the maximum extent possible.Segment VI of the liver is often excised“innocently”.This article aims to discuss the experience of the right hemihepatectomy with the segment VI preserved.Case presentation:The clinical medical records of 7 patients with right lobe liver cancer who underwent right hemihepatectomy with segment VI preservation during 2015–2021 were collected to selectively reconstruct the right hepatic vein to ensure liver blood return at segment VI.Conclusions:Right hemihepatectomy with segment VI preservation can preserve more liver parenchyma and is a safe and reliable surgical method for patients who need to preserve more liver parenchyma.Shounan Lu Zhilei Su Zongrui Yangc Sheng Tai 2022iLIVER2022,1,2:0
7A SLC31A1-MEK-DNMT1-miR-124 feedback loop contributes to pancreatic cancer progression显示文摘Although the role of copper (Cu) in promoting KRas- or BRaf-mutation driven cancers via activating MEK1/2 kinases is known, the mechanism by which the copper transporter SLC31A1 (CTR1) is upregulated in pancreatic cancer (PDAC, KRas mutation) is not defined. In this study, we provide evidence that MEK signal maintains a high level of SLC31A1 through silencing the expression of miR-124-3P (miR-124) via a novel MEK-DNMT1-miR-124 feedback loop in PDAC cells. Further, we reveal that miR-124 directly targets suppression of SLC31A1, and miR-124 introduction together with tetrathiomolybdate (TM) treatment hampered pancreatic cancer growth in vitro and in vivo. Our results demonstrate that a SLC31A1-MEK-DNMT1-miR-124 feedback loop is an important pathway to maintain copper absorption and promote pancreatic cancer progression, and we hope to provide a Cu-chelation as an adjuvant treatment strategy, to block the progression in Kras mutant PDAC patients.Jing Jin Mingjun Ma Bingru Yan Botao Qiu Shounan Lu Lin Yang Yuzhe Nie Sheng Tai Ze Yu Chun-Bo Teng 2023Genes & Diseases2023,10,3:0
8关于先进核能系统的经济性显示文摘从中子经济性角度对不同先进核能系统的嬗变(或增殖)经济性作初步分析和比较LI SHOUNAN (China Institute of Atomic Energy) (Manuscript received 8 August,1997) 1998核科学与工程1998,18,4:0
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