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| 1 | 二甲双胍与吡格列酮两种2型糖尿病药物在亲水作用色谱上的保留机理研究(英文)显示文摘二甲双胍和吡格列酮是治疗2型糖尿病的常见药物,经常用于同一复方制剂。制药和临床领域常要求同时测定这两种药物。亲水作用色谱近来在医药分析领域展现出良好的前景。本文通过研究流动相的有机溶剂含量、pH值和缓冲盐浓度等参数对色谱保留的影响,从而尝试揭示两种药物在亲水性硅胶柱上的分离机理。流动相中甲醇的增加会导致二甲双胍的保留因子的增加。流动相pH值比较低时,二甲双胍的保留因子会随着pH值升高而增加,而当pH值>6.09,其反而会随着pH值的升高而下降。吡格列酮的保留因子几乎不受甲醇比例和pH值的影响。缓冲盐浓度对两种药物的保留因子几乎都没有影响。因此,对于二甲双胍,亲水作用是主要的保留机理,静电作用和氢键也起到了重要作用。对于吡格列酮,亲水作用是支配性的。经过优化的亲水作用色谱方法可成功地应用到分离测定两种药物在2型糖尿病复方药物中的含量。 | 鲁肖飞 Caroline Martin 戚忠林 Pari Samani Zemen Berhe Dominic B Siaw Shyam K Pahari 左跃钢 | 2019 | 分析科学学报2019，35，6： | 4 |
| 2 | UNDERSTANDING THE MECHANICAL PROPERTIES OF SINGLE MICRO-PARTICLES AND THEIR COMPACTION BEHAVIOUR显示文摘The compaction of particulate materials to form tablets is increasingly employed as a final dosage form for functional products due to its simplicity and low cost. However, the functionality of some products may be impaired due to the high compression pressures required. The general aim of the current study is to understand the relationship between the mechanical properties of single feed particles (< 100 μm) and their compaction behaviour in order to produce tablets at low compression pressure with acceptable strength. The materials studied were pharmaceutical excipients, comprising three enteric polymer particles and three different powders in the form of agglomerates. The mechanical properties of the individual particles or agglomerates were determined by a micromanipulation technique. The samples were also com- pacted in cylindrical tableting dies. It was observed that there was a strong correlation between the forces required to cause the fracture of the single particles and those derived from the compaction measurements as determined using an existing analysis. | Siaw Fung Yap Michael Adams Jonathan Seville Zhibing Zhang | 2006 | China Particuology2006，4，1： | 2 |
| 3 | 中小学校长教学领导力量表编制及测量显示文摘校长教学领导力在学校发展中发挥着重要的作用,编制校长教学领导力量表有助于提升校长的领导效能。本研究基于我国教育政策与实践需求的视角编制了适合本土教育情境的中小学校长教学领导力量表,包括四项教学领导力职能、八个维度和70个行为锚定项。四项教学领导力职能分别是领导概念、教学管理、环境规划和师生管理。根据量表测量学公认标准对260名教师进行技术分析,包括探索性因素分析、信度分析和验证性因素分析。量表显示出了较高的效度和信度,表明此量表适用于测量中小学校长的教学领导力。 | Siaw Yan-Li 张灵 江娜 | 2021 | 教育观察2021，10，39： | 2 |
| 4 | Investigation on the ignition of a MEMS solid propellant microthruster before propellant combustion显示文摘 | Zhang Kai-li Siaw Kiang Chou Simon S Ang | | 0，，： | 1 |
| 5 | Designand construction of non-imaging planar concentrator forconcentrator photovoltaic system显示文摘 | CHONG K K SIAW F L WONG C W | 2009 | Renewable Energy2009，34，13： | 1 |
| 6 | Advances in pediatric gastroenterology: introducing video camera capsule endoscopy 显示文摘 | Siaw EO | 2006 | J Ark Med Soc2006，102，10： | 1 |
| 7 | Fuel injection strategies for performance improvement and emissions reduction in compression ignition engines-a review显示文摘 | Balaji Mohan Wenming Yang Siaw kiang Chou | 2013 | Renewable and Sustainable Energy Reviews2013，，28： | 1 |
| 8 | The relationships between gas production and chemical composition of 23 browses of the Genus sesbania显示文摘 | Nsahlai I V Siaw D E K A Osuji P O | 1994 | Journal Science of Food and Agriculture1994，65，： | 1 |
| 9 | Comments on mutual authentication and key exchange protocols for low power wireless communications显示文摘 | SIAW L N CHRIS M | 2004 | IEEE communications letters2004，8，4： | 1 |
| 10 | Immobilization of aminoacylase in polyethylenimine stabilized calcium alginate beads for L-phenylalanine production显示文摘 | LEE PAT M LEE KONG H SIAW YEW S | 1993 | Biomaterials Artificial Cells and Immobilization Biotechnology1993，21，4： | 1 |
| 11 | The relationships between gas production and chemical of 23 browses of the genus sesbania 显示文摘 | Nsahlai I V Siaw D E K A Osuji P O | 1994 | Journal of Science Food Agriculture1994，65，： | 1 |
| 12 | 1,25-dihydroxyvitamin D-stimulated calmodulin binding proteins:a sustained effect on distal tubules显示文摘 | Walters WR | 2002 | Am J Physiol Renal Physiol2002，282，1： | 1 |
| 13 | Design and construction of non-imaging planar concentrator for con- centrator photovoltaic system 显示文摘 | Chong K K Siaw F L Wong C W | 2009 | Renewable Energy2009，34，5： | 1 |
| 14 | Proteome database of hepatocellular carcinoma显示文摘 | Rosa C.M.Y Liang Jason C.H Neo Siaw Ling Lo Gek San Tan Teck Keong Seow Maxey C.M Chung | 2002 | Journal of Chromatography B2002，，1： | 1 |
| 15 | Advances in pediatric gastroenterology:introducing video camera capsule endoscopy显示文摘 | Siaw E O | | 0，，10： | 1 |
| 16 | Design and construction of non-imaging planar concentrator for concentrator photovoltaic system显示文摘 | Chong K K Siaw F L Wong C W | 2009 | Renewable Energy2009，34，13： | 1 |
| 17 | Eosinophilic gastroenteritis presenting as acute gastric perforation 显示文摘 | Siaw EK Sayed K Jackson RJ | 2006 | J Pediatr Gastroenterol Nutr2006，43，5： | 1 |
| 18 | Development of Cloud Movement Prediction Method for Solar Photovoltaic System显示文摘Variability of power generation due to the prevalence of cloud cover over solar photovoltaics(PV)power plants is a challenge faced by grid operators and independent system operators(ISOs)in the integration of solar energy into the grid.Solar forecasts generated through ground⁃based sky imaging systems are useful for short⁃term cloud motion predictions.However,the cost of sky imaging systems currently available in industries is relatively high.Hence,a ground⁃based camera system utilizing a simple webcam is proposed in this study.The proposed method can produce predictions with high levels of accuracy.Forecasts were generated through video analysis using MATLAB for the computation of cloud motion predictions.The image processing involved in the implementation of the proposed system is based on the detection of cloud regions in the form of a cluster of white pixels within individual frames and tracking their motion through comparison of subsequent frames.This study describes the techniques and processes used in the development of the proposed method,along with the evaluation of performance through analysis of the results.The predictions were carried out over multiple time horizons.The time horizons selected include 5,10,15,20,25,and 30 s.The overall results computed showed promising accuracy levels above 94.60%,which makes it adequate for generating reliable forecasts. | Fei Lu Siaw Yaw Yoong Sia Mallikarachchi Dilshani | 2022 | Journal of Harbin Institute of Technology(New Series)2022，29，1： | 1 |
| 19 | Hcc-2, a novel mammalian ER thioredoxin that is differentially expressed in hepatocellular carcinoma显示文摘 | Peter Morin Nissom Siaw Ling Lo Jennifer Chi Yi Lo Peh Fern Ong Justin Wee Eng Lim Keli Ou Rosa Cynthia Liang Teck Keong Seow Maxey Ching Ming Chung | 2006 | FEBS Letters2006，，9： | 1 |
| 20 | The relationships be- tween gas production and chemical composition of 23 browses of the Genus sesbania显示文摘 | Nsahlai I V Siaw D E K A Osuji P O | 1994 | Journal Science of Food Agricul- ture1994，65，1： | 1 |
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