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| 1 | Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats显示文摘Clinical and animal studies have indicated that propofol has potential for abuse,but the specific neurobiological mechanism underlying propofol reward is not fully understood.The purpose of this study was to investigate the role of extracellular signal-regulated kinase(ERK) signal transduction pathways in the nucleus accumbens(NAc) in propofol self-administration.We tested the expression of p-ERK in the NAc following the maintenance of propofol self-administration in rats.We also assessed the effect of administration of SCH23390,an antagonist of the D1 dopamine receptor,on the expression of p-ERK in the NAc in propofol self-administering rats,and examined the effects of intra-NAc injection of U0126,an MEK inhibitor,on propofol reinforcement in rats.The results showed that the expression of p-ERK in the NAc increased significantly in rats maintained on propofol,and pre-treatment with SCH23390 inhibited the propofol selfadministration and diminished the expression of p-ERK in the NAc.Moreover,intra-NAc injection of U0126(4 μg/side) attenuated the propofol self-administration.The data suggest that ERK signal transduction pathways coupled with D1 dopamine receptors in the NAc may be involved in the maintenance of propofol self-administration and its rewarding effects. | Benfu Wang Xiaowei Yang Anna Sun Lanman Xu Sicong Wang Wenxuan Lin Miaojun Lai Huaqiang Zhu Wenhua Zhou Qingquan Lian | 2016 | Neuroscience Bulletin2016,32,6: | 12 |
| 2 | Spraying printing of liquid metal electronics on various clothes to compose wearable functional device显示文摘Liquid metal printing is emerging as an important tool for making wearable electronics. However, very limited academic efforts were made to fulfill such an increasing need. This paper is dedicated to present relatively complete theoretical and experimental characterizations for liquid metal spraying printing towards developing wearable electronic textile. The practical conditions of liquid metal droplets in the spraying printing process such as the jet velocity, the size distribution of droplets and their evenness degree, the morphology of droplets and their unrolling areas after impacting the substrate are quantified. The dominating factors, including the oxidation of liquid metal and the pressure force on cloth substrate during the impacting process, which ensure liquid metal firmly adhere to the cloth, are clarified. Further, various clothes are comparatively investigated to test their capabilities in printing liquid metal conductors, where the resistance difference can be over thousand-fold. In addition to interpreting the basic mechanisms and performances of the spraying printing, two programmable flexible circuits with specifically designed functions such as blinking LED lighting and wireless infrared temperature measurement via current manufacture technology were also demonstrated and evaluated for their washable ability. With the realization of wearable modules via liquid metal printing technology, it can be expected that flexible functional devices on cloth fabricated quickly and directly would witness more broad applications in the coming time. | GUI Han TAN SiCong WANG Qian YU Yang LIU FuJun LIN Ju LIU Jing | 2017 | Science China(Technological Sciences)2017,60,2: | 8 |
| 3 | Electrically driven chip cooling device using hybrid coolants of liquid metal and aqueous solution显示文摘Heat dissipation of electronic devices keeps as a tough issue for decades. As the most classical coolant in a convective heat transfer process, water has been widely adopted which however inherits with limited thermal conductivity and relies heavily on mechanical pump. As an alternative, the room temperature liquid metal was increasingly emerging as an important coolant to realize much stronger enhanced heat transfer. However, its thermal capacity is somewhat lower than that of water, which may restrict the overall cooling performance. In addition, the high cost by taking too much amount of liquid metal into the device also turns out to be a big concern for practical purpose. Here, through combining the individual merits from both the liquid metal with high conductivity and water with large heat capacity, we proposed and demonstrated a new conceptual cooling device that integrated hybrid coolants, radiator and annular channel together for chip thermal management. Particularly, the electrically induced actuation effect of liquid metal was introduced as the only flow driving strategy, which significantly simplified the whole system design. This enables the liquid metal sphere and its surrounding aqueous solution to be quickly accelerated to a large speed under only a very low electric voltage. Further experiments demonstrated that the cooling device could effectively maintain the temperature of a hotpot(3.15 W/cm^2) below 55oC with an extremely small power consumption rate(0.8 W). Several situations to simulate the practical working of the device were experimentally explored and a theoretical thermal resistance model was established to evaluate its heat transfer performance. The present work suggests an important way to make highly compact chip cooling device, which can be flexibly extended into a wide variety of engineering areas. | TAN SiCong ZHOU YiXin WANG Lei LIU Jing | 2016 | Science China(Technological Sciences)2016,59,2: | 7 |
| 4 | False data injection attacks against smart grid state estimation:Construction, detection and defense显示文摘As a typical representative of the so-called cyber-physical system,smart grid reveals its high efficiency,robustness and reliability compared with conventional power grid.However,due to the deep integration of electrical components and computinginformation in cyber space,smart grid is vulnerable to malicious attacks,especially for a type of attacks named false data injection attacks(FDIAs).FDIAs are capable of tampering meter measurements and affecting the results of state estimation stealthily,which severely threat the security of smart grid.Due to the significantinfluence of FDIAs on smart grid,the research related to FDIAs has received considerable attention over the past decade.This paper aims to summarize recent advances in FDIAs against smart grid state estimation,especially from the aspects of background materials,construction methods,detection and defense strategies.Moreover,future research directions are discussed and outlined by analyzing existing results.It is expected that through the review of FDIAs,the vulnerabilities of smart grid to malicious attacks can be further revealed and more attention can be devoted to the detection and defense of cyber-physical attacks against smart grid. | ZHANG Meng SHEN Chao HE Ning HAN SiCong LI Qi WANG Qian GUAN XiaoHong | 2019 | Science China(Technological Sciences)2019,62,12: | 6 |
| 5 | Surface effects on in-shoe plantar pressure and tibial impact during running显示文摘目的:探讨在不同表面上跑步对足底压力和胫骨加速度的影响。方法:13位男性跑步者被要求分别在水泥地、塑胶跑道、天然草地、跑步机以及配备EVA缓冲衬垫物的跑步机上以12 km/h的速度进行慢跑。用足底压力测试系统和安放在胫骨粗隆的加速度计,记录和分析足底压力与胫骨冲击的特点。结果:第一和第二足底压力峰值(发生时间)、压力时间积分、峰值压力分布在混凝土、塑胶、草地和正常的跑步机的表面间没有明显差异。在5种不同测试表面下,峰值加速度正值也无显著差异。但相比于混凝土表面,在配备EVA缓冲衬垫物的跑步机上跑步能明显减小在冲击阶段的足底压力第一峰值和压力积分(p<0.05)。上述结果可进一步归因为足后跟区域峰值压力下降(P<0.05)。结论:运动表面和下肢冲击之间也许并无必然关系。然而值得注意的是,在解释足底压力的表现及将其运用到陆地表面的跑步运动中时应考虑不同跑步机表面的影响。 | Weijie Fu Ying Fang David Ming Shuo Liu Lin Wang Sicong Ren Yu Liu | 2015 | Journal of Sport and Health Science2015,4,4: | 4 |
| 6 | Dual-shot dynamics and ultimate frequency of all-optical magnetic recording on GdFeCo显示文摘Although photonics presents the fastest and most energy-efficient method of data transfer,magnetism still offers the cheapest and most natural way to store data.The ultrafast and energy-efficient optical control of magnetism is presently a missing technological link that prevents us from reaching the next evolution in information processing.The discovery of all-optical magnetization reversal in GdFeCo with the help of 100fs laser pulses has further aroused intense interest in this compelling problem.Although the applicability of this approach to high-speed data processing depends vitally on the maximum repetition rate of the switching,the latter remains virtually unknown.Here we experimentally unveil the ultimate frequency of repetitive all-optical magnetization reversal through time-resolved studies of the dual-shot magnetization dynamics in Gd27 Fe63.87 C09.T3.Varying the intensities of the shots and the shotto-shot separation,we reveal the conditions for ultrafast writing and the fastest possible restoration of magnetic bits.It is shown that although magnetic writing launched by the first shot is completed after 100 ps,a reliable rewriting of the bit by the second shot requires separating the shots by at least 300 ps.Using two shots partially overlapping in space and minimally separated by 300 ps,we demonstrate an approach for GHz magnetic writing that can be scaled down to sizes below the diffraction limit. | Sicong Wang Chen Wei\Yuanhua Feng Hongkun Cao Wenzhe Li Yaoyu Cao Bai-Ou Guan Arata Tsukamoto Andrei Kirilyuk Alexey VKimel Xiangping Li | 2021 | Light(Science & Applications)2021,10,1: | 3 |
| 7 | Surface Oxygen Injection in Tin Disulfide Nanosheets for Efficient CO_(2) Electroreduction to Formate and Syngas显示文摘Surface chemistry modification represents a promising strategy to tailor the adsorption and activation of reaction intermediates for enhancing activity.Herein,we designed a surface oxygen-injection strategy to tune the electronic structure of SnS_(2) nanosheets,which showed effectively enhanced electrocatalytic activity and selectivity of CO_(2) reduction to formate and syngas(CO and H_(2)).The oxygen-injection SnS_(2) nanosheets exhibit a remarkable Faradaic efficiency of 91.6%for carbonaceous products with a current density of 24.1 mA cm^(−2) at−0.9 V vs RHE,including 83.2%for formate production and 16.5%for syngas with the CO/H_(2) ratio of 1:1.By operando X-ray absorption spectroscopy,we unravel the in situ surface oxygen doping into the matrix during reaction,thereby optimizing the Sn local electronic states.Operando synchrotron radiation infrared spectroscopy along with theoretical calculations further reveals that the surface oxygen doping facilitated the CO_(2) activation and enhanced the affinity for HCOO*species.This result demonstrates the potential strategy of surface oxygen injection for the rational design of advanced catalysts for CO_(2) electroreduction. | Tao Chen Tong Liu Tao Ding Beibei Pang Lan Wang Xiaokang Liu Xinyi Shen Sicong Wang Dan Wu Dong Liu Linlin Cao Qiquan Luo Wei Zhang Wenkun Zhu Tao Yao | 2021 | Nano-Micro Letters2021,13,11: | 3 |
| 8 | MARVEL:Multi-Agent Reinforcement Learning for VANET Delay Minimization显示文摘In urban Vehicular Ad hoc Networks(VANETs),high mobility of vehicular environment and frequently changed network topology call for a low delay end-to-end routing algorithm.In this paper,we propose a Multi-Agent Reinforcement Learning(MARL)based decentralized routing scheme,where the inherent similarity between the routing problem in VANET and the MARL problem is exploited.The proposed routing scheme models the interaction between vehicles and the environment as a multi-agent problem in which each vehicle autonomously establishes the communication channel with a neighbor device regardless of the global information.Simulation performed in the 3GPP Manhattan mobility model demonstrates that our proposed decentralized routing algorithm achieves less than 45.8 ms average latency and high stability of 0.05%averaging failure rate with varying vehicle capacities. | Chengyue Lu Zihan Wang Wenbo Ding Gang Li Sicong Liu Ling Cheng | 2021 | China Communications2021,18,6: | 2 |
| 9 | Diffractive photonic applications mediated by laser reduced graphene oxides显示文摘 | Sicong Wang Xueying Ouyang Ziwei Feng Yaoyu Cao Min Gu Xiangping Li | 2018 | Opto-Electronic Advances2018,1,2: | 2 |
| 10 | Research on knowledge acquisition method about the IF/THEN rules based on rough set theory显示文摘The basic principles of IF/THEN rules in rough set theory are analyzed first, and then the automatic process of knowledge acquisition is given. The numerical data is qualitatively processed by the classification of membership functions and membership degrees to get the normative decision table. The regular method of relations and the reduction algorithm of attributes are studied. The reduced relations are presented by the multi-represent-value method and its algorithm is offered. The whole knowledge acquisition process has high degree of automation and the extracted knowledge is true and reliable. | Liu Daohua Yuan Sicong Zhang Xiaolong Wang Fazhan | 2008 | Journal of Systems Engineering and Electronics2008,19,3: | 2 |
| 11 | Soliton and bound-state soliton mode-locked fiber laser based on a MoS_2/fluorine mica Langmuir–Blodgett film saturable absorber显示文摘In this article, we report on an experimentally generated soliton and bound-state soliton passively mode-locked erbium-doped fiber laser by incorporating a saturable absorber(SA) made of MoS2∕fluorine mica(FM) that was fabricated with the Langmuir–Blodgett(LB) method. The FM substrate is 20 μm thick and easy to bend or cut,like a polymer. However, it has a higher damage threshold and a better thermal dissipation than polymers.In addition, the LB method can be used to fabricate a thin film with good uniformity. In this study, the modulation depth, saturable intensity, and unsaturated loss of the SA are measured as 5.9%, 57.69 MW∕cm2, and13.4%, respectively. Based on the SA, a soliton mode-locked laser is achieved. The pulse duration, repetition rate, and signal-to-noise ratio are 581 fs, 15.67 MHz, and 65 dB, respectively. By adjusting the polarization controller and pump power, we obtain a bound-state soliton mode-locked pulse. The temporal interval between the two solitons forming the bound-state pulse is 2.7 ps. The repetition rate of the bound-state pulses is proportional to the pump power. The maximum repetition rate is 517 MHz, corresponding to the 33 rd harmonic of the fundamental repetition rate. The results indicate that the MoS2∕FM LB film absorber is a promising photonic device in ultrafast fiber lasers. | RUIDONG Lü YONGGANG WANG JIANG WANG WEI REN LU LI SICONG LIU ZHENDONG CHEN YONGFANG LI HONGYING WANG FUXING FU | 2019 | Photonics Research2019,7,4: | 2 |
| 12 | Effects of Diet with 'Lianteng' Additive of Chinese Herbal Medicine on Blood Biochemical Indexes,Immune and Antioxidant Function of Guangxi Sanhuang Chickens显示文摘[Objectives]This trial was conducted to investigate the effects of diet with'Lianteng'additive of Chinese herbal medicine on blood biochemical indexes,immune and antioxidant function of Guangxi Sanhuang chickens.[Methods]480 Guangxi Sanhuang chickens at the age of 1 d were divided into 4 groups randomly and each group was assigned to 6 replicates with 20 chicks in each replicate;groups A,B and C were treatment groups and fed basal diets with 0.1%,0.2%and 0.4%of'Lianteng'additive of Chinese herbal medicine respectively during a trial of 70 d.Group D was control group and fed only basal diet.The serum samples were taken from 6 chicks in each group at the age of 21,35 and 49 d respectively and analyzed for biochemical,immune and antioxidant parameters in serum.[Results]Results from the trial showed that no difference was found in serum content of GLU,TG,TP,TC,and UN in the measurement at the age of 21,35 and 49 d(P>0.05);however,the content of ALB from groups A and B at 35 d was significantly higher than that from group D(P<0.01),and the ALB content from group B at 49 d was also higher than that from group D(P<0.05);the IgM content at 49 d from group A was lower than that from group D(P<0.05),in addition to this,there was no differences found in the contents of IgG,IgM and IFN-y among groups A,B,C and D during the trial(P>0.05);but the content of IL-2 from groups A and B at 49 d was significantly greater than that from group D(P<0.05);T-AOC from groups A,B and C at 49 d was very significantly higher than that from group D(P<0.01),and the one of group B at 35 d was still obviously higher than that of group D(P<0.05);also at 49 d,the GSH content in groups A and B was much greater than that in group D(P<0.01);T-SOD activity of group B and C at 35 d was distinctly greater than that of group D(P<0.05).[Conclusions]It can be concluded that the addition of 0.2%of'Lianteng'additive of Chinese herbal medicine in diet can increase immune function in a certain extent and promote the antioxidant ability observably for Guangxi Sanhuang chickens. | Sicong LUO Wenjie LU Lizhi LU Fulin WANG Qian QIN Cui YANG Jiahuang YANG | 2021 | Medicinal Plant2021,12,1: | 1 |
| 13 | Biomass-derived hard carbon microtubes with tunable apertures for high-performance sodium-ion batteries显示文摘Sodium-ion batteries(SIBs)are considered the most up-and-coming complements for large-scale energy storage devices due to the abundance and cheap sodium.However,due to the bigger radius,it is still a great challenge to develop anode materials with suitable space for the intercalation of sodium ions.Herein,we present hard carbon microtubes(HCTs)with tunable apertures derived from low-cost natural kapok fibers via a carbonization process for SIBs.The resulted HCTs feature with smaller surface area and shorter Na+diffusion path benefitting from their unique micro-nano structure.Most importantly,the wall thickness of HCTs could be regulated and controlled by the carbonization temperature.At a high temperature of 1,600℃,the carbonized HCTs possess the smallest wall thickness,which reduces the diffusion barrier of Na+and enhances the reversibility Na+storage.As a result,the 1600HCTs deliver a high initial Coulombic efficiency of 90%,good cycling stability(89.4%of capacity retention over 100 cycles at 100 mA·g^(−1)),and excellent rate capacity.This work not only charts a new path for preparing hard carbon materials with adequate ion channels and novel tubular micro-nano structures but also unravels the mechanism of hard carbon materials for sodium storage. | Pin Song Shiqiang Wei Jun Di Jun Du Wenjie Xu Daobin Liu Changda Wang Sicong Qiao Yuyang Cao Qilong Cui Pengjun Zhang Liaobo Ma Jiewu Cui Yan Wang Yujie Xiong | 2023 | Nano Research2023,16,4: | 1 |
| 14 | Progress of optically pumped GaSb based semiconductor disk laser显示文摘 | Shili Shu Guanyu Hou Jian Feng Lijie Wang Sicong Tian Cunzhu Tong Lijun Wang | 2018 | Opto-Electronic Advances2018,1,2: | 1 |
| 15 | Effect ofCa and Nd alloying on the microstructure of Mg-6Al-Ca-Nd alloy 显示文摘 | Feng Yicheng Wang Qin Zhao Sicong | 2015 | Advanced Materials Research2015,1095,: | 1 |
| 16 | Three-dimensional measurement of a tightly focused laser beam显示文摘 | Xie Xiangsheng Li li Wang Sicong | 2013 | AIP Advances2013,3,02: | 1 |
| 17 | An Efficient Approach to Predict Far Field Pattern in FDTD Simulation 显示文摘 | Baixin Zhou Sicong Wang Wenhua Yu | 2004 | IEEE Antennas and Wireless Propagation Letters (S1536-1225)2004,3,: | 1 |
| 18 | An intravenous clarithromycin lipid emulsion with a high drug loading, H-bonding and a hydrogen-bonded ion pair complex exhibiting excellent antibacterial activity显示文摘The aim of this study was to develop an intravenous clarithromycin lipid emulsion(CLE)with good stability and excellent antibacterial activity. The CLE was prepared by the thinfilm dispersed homogenization method. The interaction between clarithromycin(CLA) and cholesteryl hemisuccinate(CHEMS) was confirmed by DSC, FT-IR and^1H NMR analysis. The interfacial drug loading, thermal sterilization, freeze–thaw stability, and in vitro and in vivo antibacterial activity were investigated systematically. DSC, FT-IR and^1H NMR spectra showed that CHEMS(CLA: CHEMS, M ratio 1:2) could interact with CLA through H-bonding and a hydrogen-bonded ion pair. The CHEMS was found necessary to maintain the stability of CLE.Ultracentrifugation showed that almost 88% CLA could be loaded into the interfacial layer.The optimized CLE formulation could withstand autoclaving at 121 °C for 10 min and remain stable after three freeze–thaw cycles. The in vitro susceptibility test revealed that the CLA–CHEMS ion-pair and CLE have similar activity to the parent drug against many different bacterial strains. The in vivo antibacterial activity showed that the ED50 of intravenous CLE was markedly lower than that of CLA solution administrated orally. CLE exhibited pronounced antibacterial activity and might be a candidate for a new nanocarrier for CLA with potential advantages over the current commercial formulation. | Haoyu Gong Sicong Geng Qi Zheng Puxiu Wang Lifeng Luo Xiuzhi Wang Yan Zhang Yu Zhang Haibing He Xing Tang | 2016 | Asian Journal of Pharmaceutical Sciences2016,11,5: | 1 |
| 19 | Liquid metal corrosion sculpture to fabricate quickly complex patterns on aluminum显示文摘A liquid metal enabled corrosion sculpture technique for quickly fabricating complex patterns on aluminum substrate is proposed and experimentally demonstrated.According to the conceptual investigation,it is clarified that the width and the depth of a printed track are dominated by sculpture time and working temperature.The printed size can reach small values of 3 8 μm through controlling the sculpture time for 60 s.As the sculpture time was increased from 5 to 25 min at 20℃,the depth of the fabricated pattern was improved from 13.3 to 25.6 μm.The sculptured depth of the pattern would increase from 13.3 to 106.9 μm when the sculpture time was fixed at 5 min and the temperature was raised from 20 to 60℃.To investigate the sculpture behavior in detail,the phases and microstructure of sculpture surface were quantitatively measured via a group of microscope imaging system with fundamental mechanisms interpreted.The present liquid metal sculpture method on aluminum substrate adds a new valuable soft tool for current metal engraving technology family. | LU JinRong YI LiTing WANG Lei TAN SiCong GUI Han LIU Jing | 2017 | Science China(Technological Sciences)2017,60,1: | 1 |
| 20 | A diet-induced type 2 diabetes model in Drosophila显示文摘Dear Editor.Type 2 diabetes has become a global epidemic.It is a disease characterized by insulin resistance and relative insulin deficiency,resulting in hyperglycemia and various physiological and metabolic abnormalities.Besides genetic risk factors,inappropriate life styles,such as lack of physical activity and imbalanced diet,also contribute to the development of type 2diabetes in human(Jia et al.,2019).Animal models of type 2diabetes are of great value to understand its underlying mechanisms as well as to develop and evaluate potential diagnostic and therapeutic options(Kleinert et al.,2018). | Danping Chen Jie Yang Zhengyun Xiao Sicong Zhou Liming Wang | 2021 | Science China(Life Sciences)2021,64,2: | 1 |