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| 1 | Hepatocellular carcinoma: Review of disease and tumor biomarkers显示文摘Hepatocellular carcinoma(HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative treatments is limited to early stage cancers, diagnosis in non-symptomatic individuals is crucial. International guidelines advise regular surveillance of high-risk populations but the current tools lack sufficient sensitivity for early stage tumors on the background of a cirrhotic nodular liver. A number of novel biomarkers have now been suggested in the literature, which may reinforce the current surveillance methods. In addition, recent metabonomic and proteomic discoveries have established specific metabolite expressions in HCC, according to Warburg's phenomenon of altered energy metabolism. With clinical validation, a simple and non-invasive test from the serum or urine may be performed to diagnose HCC, particularly benefiting low resource regions where the burden of HCC is highest. | Jin Un Kim Mohamed I F Shariff Mary M E Crossey Maria Gomez-Romero Elaine Holmes I Jane Cox Haddy K S Fye Ramou Njie Simon D Taylor-Robinson | 2016 | World Journal of Hepatology2016，8，10： | 13 |
| 2 | Imaging of liver cancer显示文摘Improvements in imaging technology allow exploitation of the dual blood supply of the liver to aid in the identif ication and characterisation of both malignant and benign liver lesions. Imaging techniques available include contrast enhanced ultrasound, computed tomography and magnetic resonance imaging. This review discusses the application of several imaging techniques in the diagnosis and staging of both hepatocellular carcinoma and cholangiocarcinoma and outlines certain characteristics of benign liver lesions. The advantages of each imaging technique are highlighted, while underscoring the potential pitfalls and limitations of each imaging modality. | Ben Ariff Claire R Lloyd Sameer Khan Mohamed Shariff Andrew V Thillainayagam Devinder S Bansi Shahid A Khan Simon D Taylor-Robinson Adrian KP Lim | 2009 | World Journal of Gastroenterology2009，15，11： | 4 |
| 3 | Global Wheat Head Detection 2021:An Improved Dataset for Benchmarking Wheat Head Detection Methods显示文摘The Global Wheat Head Detection(GWHD)dataset was created in 2020 and has assembled 193,634 labelled wheat heads from 4700 RGB images acquired from various acquisition platforms and 7 countries/institutions.With an associated competition hosted in Kaggle,GWHD_2020 has successfully attracted attention from both the computer vision and agricultural science communities.From this first experience,a few avenues for improvements have been identified regarding data size,head diversity,and label reliability.To address these issues,the 2020 dataset has been reexamined,relabeled,and complemented by adding 1722 images from 5 additional countries,allowing for 81,553 additional wheat heads.We now release in 2021 a new version of the Global Wheat Head Detection dataset,which is bigger,more diverse,and less noisy than the GWHD_2020 version. | Etienne David Mario Serouart Daniel Smith Simon Madec Kaaviya Velumani Shouyang Liu Xu Wang Francisco Pinto Shahameh Shafiee Izzat SATahir Hisashi Tsujimoto Shuhei Nasuda Bangyou Zheng Norbert Kirchgessner Helge Aasen Andreas Hund Pouria Sadhegi-Tehran Koichi Nagasawa Goro Ishikawa Sébastien Dandrifosse Alexis Carlier Benjamin Dumont Benoit Mercatoris Byron Evers Ken Kuroki Haozhou Wang Masanori Ishii Minhajul ABadhon Curtis Pozniak David Shaner LeBauer Morten Lillemo Jesse Poland Scott Chapman Benoit de Solan Frédéric Baret Ian Stavness Wei Guo | 2021 | Plant Phenomics2021，3，1： | 2 |
| 4 | Synthesis of CMP-NeuAc from N-acetylglucosamine: Generation of CTP from CMP using adenylate kinase 显示文摘 | Simon E S Bednarski M D Whitesides G M | 1988 | J Am Chem Soc1988，110，： | 2 |
| 5 | Mayo clinic Scottsdale experience with laparoscopic nephron sparing surgery for renal tumors 显示文摘 | Simon S D Ferrigni R G Novicki D E | 2003 | J Urol2003，169，6： | 1 |
| 6 | Stability of clay minerals in acid显示文摘 | Simon D E Anderson M S | 1942 | SPE1942，2，： | 1 |
| 7 | Advertising and the diffusion of new products 显示文摘 | Horsky D Simon L S | 1983 | Marketting Science1983，，： | 1 |
| 8 | Hand hygiene among physicians:performance,beliefs and perceptions显示文摘 | Pittet D Simon A Hugonnet S | | 0，，01： | 1 |
| 9 | Long-term multiple color imaging of live cells using quantum dot bioconjugates显示文摘 | JAISWAL J K MATTOUSSI H D SIMON S M | 2003 | Nature Biotechnol2003，21，1： | 1 |
| 10 | Reaction of o-phthalaldehyde and thiols with primary amines: formation of 1-alkyl(and aryl) thio-2-alkylisoindoles显示文摘 | Simons JR S Johnson D F | 1978 | J Org Chem1978，43，14： | 1 |
| 11 | Neurobehavioral function and tibial and chelatable lead levels in 543 former organo lead workers显示文摘 | STEWART W F SCHWARIZ B S SIMON D | 1999 | Neurology1999，52，： | 1 |
| 12 | Anal sphincter EMG does not distinguish between multiple system atrophy and Parkinsons disease显示文摘 | Giladi N Simon E S Korczyn A D | 2000 | Muscle Nerve2000，23，5： | 1 |
| 13 | Unified forms for Kalman and finite impulse response filtering and smoothing显示文摘 | Simon D Shmaliy Y S | | 0，，06： | 1 |
| 14 | A review of ac- celerated carbonation technology in the treatment of cement- based materials and sequestration 'of CO2 显示文摘 | Fernandez Bertos M Simons S J R Hills C D | 2004 | Journal of Hazard- ous Materia/s2004，112，3： | 1 |
| 15 | An adaptive optical flow technique for person tracking systems 显示文摘 | Simon D Vinod C Sridha S | 2007 | Pattern Recognition Letters2007，28，10： | 1 |
| 16 | A novel FIP1LI-PDGFRA mutant destabilizing the inactive conformation of the kinase domain in chronic eosinophilic leukemia/hypereosinophilic syndrome显示文摘 | Salemi S Yousefi S Simon D | 2009 | Allergy2009，64，6： | 1 |
| 17 | Management of dissociated vertical deviation显示文摘 | Lehman S Bacal D Simon J | 2005 | J Pediatr Ophthalmol Strabismus2005，42，5： | 1 |
| 18 | Generation of cytidine 5'-triphosphate using adenylatekinase显示文摘 | SIMON E S BEDNARSKI M D WHITESIDES G M | 1988 | Tetrahedron Letters1988，29，10： | 1 |
| 19 | Reduced thickness of ante- rior cingulate cortex in obsessive compulsive disorder显示文摘 | Kuhn S Kaufmann C Simon D | 2013 | Cortex2013，49，8： | 1 |
| 20 | Fulvcstrant ('Faslodex'):clinical experience from the Compassionate Use Programme显示文摘 | STEGER G G GIPS M SIMON S D | | 0，，2： | 1 |
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