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| 1 | The DnaA protein determines the initiation mass of Escherichia coli K-12显示文摘 | LOBNER-OLESEN A SKARSTAD K HANSEN F G VON MEYENBURG K BOYE E | 1989 | Cell1989,57,5: | 1 |
| 2 | Battery and capacitor technology for uniform charge time in implantable cardioverter-defibrillators显示文摘 | Skarstad P M | 2004 | J Power Sources2004,136,2: | 1 |
| 3 | The initiator protein DnaA:evolution,properities and function显示文摘 | Skarstad K Boye E | | 0,,: | 1 |
| 4 | Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the data region 显示文摘 | MORIGEN BOYE E SKARSTAD K | 2001 | Biochim Biophys Acta2001,1521,13: | 1 |
| 5 | Stable co-existence of separate replicons in Escherichia coli is dependent on onceper-cell-cycle initiation显示文摘 | Skarstad K Lobner-Olesen A | | 0,,: | 1 |
| 6 | Modeling and characterization of the resistance of lithium/SVO batteries for implantable cardioverter defibrillators显示文摘 | CRESPI A SCHMIDT C NORTON J CHEN K SKARSTAD P | 2001 | J Electrochem Soc2001,148,: | 1 |
| 7 | Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks,delayed replication initiation and delayed cell division显示文摘 | Morigen L(o)bner-Olesen A Skarstad K | | 0,,: | 1 |
| 8 | Limiting DNA replication to once and only once显示文摘 | Boye E Lobner-Olesen A Skarstad K | | 0,,: | 1 |
| 9 | Characterization of silver vanadium oxide cathode material by high-resolution electron microscopy 显示文摘 | Crespi A M Skarstad P Zandbergen H W | 1995 | Journal of Power Sources1995,54,1: | 1 |
| 10 | The Escherichia coli SeqA protein binds specifically and cooperatively to two sites in hemimethylated and fully methylated oriC显示文摘 | Skarstad K Lueder G Lurz | | 0,,: | 1 |
| 11 | Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC显示文摘 | Torheim NK Skarstad K | | 0,,: | 1 |
| 12 | Lack of SeqA focus formation,specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2显示文摘 | Fossum S Soreide S Skarstad K | | 0,,: | 1 |
| 13 | Positive supercoiling is generated in the presence of Escherichia coli SeqA protein显示文摘 | Klungsoyr HK Skarstad K | | 0,,: | 1 |
| 14 | Excess SeqA prolongs sequestration and cell division显示文摘 | Bach T Krekling M Skarstad K | | 0,,: | 1 |
| 15 | Battery and capacitor technology for uniform charge time in implantable cardioverter-defibrillators 显示文摘 | Skarstad P M | 2004 | Journal of Power Sources2004,136,2: | 1 |
| 16 | Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain显示文摘Background:Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer’s disease(AD).These beneficial effects may be partly mediated by blood-borne factors.Here we used an in vitro model of AD to investigate effects of blood plasma from exercise-trained donors on neuronal viability,and an in vivo rat model of AD to test whether such plasma impacts cognitive function,amyloid pathology,and neurogenesis.Methods:Mouse hippocampal neuronal cells were exposed to AD-like stress using amyloid-βand treated with plasma collected from human male donors 3 h after a single bout of high-intensity exercise.For in vivo studies,blood was collected from exercise-trained young male Wistar rats(high-intensity intervals 5 days/week for 6 weeks).Transgenic AD rats(McGill-R-Thyl-APP)were inj ected 5 times/fortnight for 6 weeks at2 months or 5 months of age with either(a)plasma from the exercise-trained rats,(b)plasma from sedentary rats,or(c)saline.Cognitive function,amyloid plaque pathology,and neurogenesis were assessed.The plasma used for the treatment was analyzed for 23 cytokines.Results:Plasma from exercised donors enhanced cell viability by 44.1%(p=0.032)and reduced atrophy by 50.0%(p<0.001)in amyloid-β-treated cells.In vivo exercised plasma treatment did not alter cognitive function or amyloid plaque pathology but did increase hippocampal neurogenesis by~3 fold,regardless of pathological stage,when compared to saline-treated rats.Concentrations of 7 cytokines were significantly reduced in exercised plasma compared to sedentary plasma.Conclusion:Our proof-of-concept study demonstrates that plasma from exercise-trained donors can protect neuronal cells in culture and promote adult hippocampal neurogenesis in the AD rat brain.This effect may be partly due to reduced pro-inflammatory signaling molecules in exercised plasma. | Cecilie Skarstad Norevik Aleksi M.Huuha Ragnhild N.RФsbjФrgen Linda Hildegard Bergersen Kamilla Jacobsen Rodrigo Miguel-dos-Santos Liv Ryan Belma Skender Jose Bianco N.Moreira Asgeir Kobro-Flatmoen Menno P.Witter Nathan Scrimgeour Atefe R.Tari | 2024 | Journal of Sport and Health Science2024,13,2: | 0 |
| 17 | A DnaA-dependent riboswitch for transcription attenuation of the his operon显示文摘Transcription attenuation in response to the availability of a specific amino acid is believed to be controlled by alternative configurations of RNA secondary structures that lead to the arrest of translation or the release of the arrested ribosome from the leader mRNA molecule.In this study,we first report a possible example of the DnaA‐dependent riboswitch for transcription attenuation in Escherichia coli.We show that(i)DnaA regulates the transcription of the structural genes but not that of the leader hisL gene;(ii)DnaA might bind to rDnaA boxes present in the HisL‐SL RNA,and subsequently attenuate the transcription of the operon;(iii)the HisL‐SL RNA and rDnaA boxes are phylogenetically conserved and evolutionarily important;and(iv)the translating ribosome is required for deattenuation of the his operon,whereas tRNA^(His) strengthens attenuation.This mechanism seems to be phylogenetically conserved in Gram‐negative bacteria and evolutionarily important. | Yuan Yao Hongwei Sun Wurihan Gegeheng Gezi Kirsten Skarstad Lifei Fan Morigen | 2023 | mLife2023,2,2: | 0 |