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| 1 | 弥漫性中线胶质瘤,组蛋白H3-K27M突变型:47例形态学变异谱系及相关遗传学改变分析显示文摘最近发现在儿童和年轻人丘脑、桥脑和脊髓的高级别胶质瘤中存在编码组蛋白H3的亚型H3.3和H3.1的H3F3A和HIST1H3B基因体细胞突变。然而,关于发生这些肿瘤的患者和部位具体范围,以及形态学谱系和相关遗传学改变仍然不确定。本文检测47例伴组蛋白H3-K27M突变的弥漫性中线胶质瘤,包括25例男性和22例女性患者,年龄2~65岁(中位年龄14岁)。肿瘤中心位置除了位于桥脑(17例)、丘脑(15例)和脊髓(9例),还可见于第三脑室(3例)、下丘脑(1例)、松果体区(1例)和小脑(1例)。 | Solomon D A Wood M D Tihan T 李晓玲 王行富 | 2016 | 临床与实验病理学杂志2016,32,9: | 49 |
| 2 | Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract显示文摘Objective:To explore the antidiabetic properties of Mucuna pruriens(M.pruriens).Methods: Diabetes was induced in Wistar rats by single intravenous injection of 120 mg/kg of alloxan monohydrate and different doses of the extract were administered to diabetic rats.The blood glucose level was determined using a glucometer and results were compared with normal and untreated diabetic rats.The acute toxicity was also determined in albino mice.Results:Results showed that the administration of 5,10,20,30,40,50,and 100 mg/kg of the crude ethanolic extract of M.pruriens seeds to alloxan-induced diabetic rats(plasma glucose > 450 mg/dL) resulted in 18.6%,24.9%,30.8%,41.4%,49.7%,53.1%and 55.4%reduction,respectively in blood glucose level of the diabetic rats after 8h of treatment while the administration of glibenclamide (5 mg/kg/day) resulted in 59.7%reduction.Chronic administration of the extract resulted in a significant dose dependent reduction in the blood glucose level(P<0.001).It also showed that the antidiabetic activity of M.pruriens seeds resides in the methanolic and ethanolic fractions of the extract.Acute toxicity studies indicated that the extract was relatively safe at low doses,although some adverse reactions were observed at higher doses(8-32 mg/kg body weight),no death was recorded.Furthermore,oral administration of M.pruriens seed extract also significandy reduced the weight loss associated with diabetes.Conclusions:The study clearly supports the traditional use of M.pruriens for the treatment of diabetes and indicates that the plant could be a good source of potent antidiabetic drug. | Stephen O Majekodunmi Ademola A Oyagbemi Solomon Umukoro Oluwatoyin A Odeku | 2011 | Asian Pacific Journal of Tropical Medicine2011,4,8: | 8 |
| 3 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004,7,4: | 3 |
| 4 | 甘蔗茎分枝:稀有的形态分离(英文)显示文摘虽然在甘蔗同节上出现多芽现象已被报道,但是却未曾发现同节多芽能独立生长成蔗茎的现象。文章阐述了2008~2009年度在甘蔗品种CoS 96268宿根蔗大田观察到的一株甘蔗植株上发生的独特的形态分离现象。在该株甘蔗地上部的第7、8节上均有2个芽,但第8节出现溢痕,将该节间分成不等的两部分;该分离部分在第9节间更为明显,并独立生长成两条蔗茎(分枝),每条蔗茎均具有正常的节间形态。 | S P Shukla Anita Sawnani S Solomon A K Shrivastava | 2010 | 广西农业科学2010,41,6: | 2 |
| 5 | 大鼠腹腔内心脏移植模型的构建和体会显示文摘目的总结在美国国立卫生研究院临床中心建立大鼠腹腔内心脏移植模型的经验,探讨手术成功的主要影响因素。方法以80只DarkAgouti大鼠为供体,70只BrownNorway大鼠为受体,制作大鼠心脏移植模型。以连续20例手术死亡率低于15%且无明显合并症为手术合格标准。结果为达到合格标准,共施行了10例大鼠供体手术,70例大鼠移植手术。最后20例移植手术成功率为95%,平均手术时间为55min,供心平均缺血时间为35min。结论精准的显微外科技术,加上标准化手术训练和严格的动物管理,是保证手术成功率的关键因素。 | 陈浩 梅运清 Michael A Solomon | 2012 | 中华医学杂志2012,92,24: | 2 |
| 6 | 尼日利亚博尔努盆地沉积地层分布特征显示文摘利用博尔努盆地内23口探井的钻井、测井资料,借助于Excel、Petrel及Surfer等软件,确定了盆地Kerri-Kerri组、Gombe组、Fika组、Gongila组和Bima组及整个沉积地层的空间分布。对整个沉积地层空间分布研究发现,博尔努盆地共有3个主要坳陷(A、C、D)和1个构造高点B。坳陷A位于盆地东北部,坳陷C和D分别位于盆地东南部和西南部,构造高点B分隔坳陷A和坳陷C。Kerri-Kerri组、Gombe组、Fika组、Gongila组和Bima组在盆地广泛分布,但地层厚度存在变化;3口深层探井(Kadaru-1井、Herwa-1井及Kinasar-1井)仅钻揭Bima组上部层段(岩性为中—粗粒长石砂岩),对Bima组下部层段尚未钻遇。因此建议针对盆地内部的潜在含油气坳陷区开展深层钻探。 | Olabode Solomon O Adekoya John A Ola Peter S | 2015 | 石油勘探与开发2015,42,5: | 2 |
| 7 | Limbal cell autograft transplantation for severe ocular surface disorders显示文摘 | Frucht-Pery J Siganos CS Solomon A | 1998 | Graefes Arch Clin Exp Ophthalmol1998,236,8: | 2 |
| 8 | Dry eye and delayed tear clearance: ''a call to arms''显示文摘 | Pflugfelder SC Solomon A Dursun D | 2002 | Adv Exp Med Biol2002,506,: | 2 |
| 9 | Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease显示文摘 | Solomon A Dursun D Liu Z | 2001 | Invest Ophthalmol Vis Sci2001,42,10: | 2 |
| 10 | Candida parapsilosis keratitis following treatment of epithelial ingrowth after laser in situ keratomileusis显示文摘 | Solomon R Biser S A Donnenfeld E D | 2004 | Eye Contact Lens2004,30,2: | 1 |
| 11 | Microstructural characterization of Ni-Mn-Ga ferromagnetic shape memory alloy powders显示文摘 | SOLOMON V C SMITH D J TANG Y J BERKOWITZ A E | 2004 | J Appl Phys2004,95,: | 1 |
| 12 | Model of visual contrast gain control and pattern masking显示文摘 | WATSON A B SOLOMON J A | 1997 | Journal of the Opti- cal Society of America a-Optics Image Science and Vi- sion1997,,9: | 1 |
| 13 | Supplementation of cottonseed meal on feed intake, digestibility, live weight and carcass parameters of Si- dama goats 显示文摘 | SOLOMON M MELAKU S TOLERA A | 2008 | Livest Sci2008,,119: | 1 |
| 14 | Antioxidant activities and anthocyanin content of fresh fruits of common fig(ficus caricaL) 显示文摘 | Solomon A Golubowicz S Yablowicz Z | 2006 | J Agric and Food Chem2006,54,20: | 1 |
| 15 | Computed tomography in bronchial atresia显示文摘 | Cohen A M Solomon E H Alfidi R J | 1980 | AJR Am J Roentgenol1980,135,5: | 1 |
| 16 | Temporal and spatial trends of mercury in fish collected in the English-Wabigoon river system in Ontario, Canada显示文摘 | Kinghorn A Solomon P Chan H M | 2007 | Science of the Total Environment2007,372,2: | 1 |
| 17 | Amniotic membrane grafts for nontraumatic corneal perforations, descemetoceles, and deep ulcers显示文摘 | Solomon A Meller D Prabhasawat P | 2002 | Ophthalmology2002,109,4: | 1 |
| 18 | Alzheimer's disease:clinical trials and drug development显示文摘 | Mangialasche F Solomon A Winblad B | | 0,,07: | 1 |
| 19 | The aspext of trauma in he bone changes of eongenital lues显示文摘 | I Solomon A Rosen E | 1975 | Pediatr Radiol1975,3,: | 1 |
| 20 | Temporal and spatial trends of mercury in fish collected in the English-Wabigoon river system in Ontario, Canada 显示文摘 | Kinghorn A Solomon P Chan H M | 2007 | Science of the Total Environment2007,372,23: | 1 |