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| 1 | Quercetin induces apoptosis by activating caspase-3 and regulating Bcl-2 and cyclooxygenase-2 pathways in human HL-60 cells显示文摘橡黄素是自然地发生之一饮食的黄酮醇混合物。它在植物富有地是在场的并且有 chemopreventive 和 anticancer 效果。调查它的 anticancer 机制,我们对尖锐白血病房间线检验了橡黄素的活动, HL-60。我们的结果证明橡黄素禁止了房间增长并且在一个时间依赖者和剂量依赖者举止导致了 apoptosis。而且,橡黄素下面调整 anti-apoptosis 蛋白质 Bcl-2 的表示并且起来调整 pro-apoptosis 蛋白质 Bax 的表示。Caspase-3 被橡黄素也激活,它开始了一条 caspase-3-depended mitochodrial 小径导致 apoptosis。橡黄素禁止了 cycloocygenase-2 (Cox-2 ) 的表示,这也被发现 mRNA 和 Cox-2 蛋白质。一起拿,这些调查结果建议橡黄素由禁止 Cox-2 表示在一条 caspase-3-dependent 小径导致 apoptosis 并且调整下游的 apoptotic 部件的表示,包括 Bcl-2 和 Bax。橡黄素能是可能安全地在白血病治疗被使用的一个有势力和有希望的药。 | Guomin Niu Songmei Yin Shuangfeng Xie Yiqing Li Danian Nie Liping Ma Xiuju Wang Yudan Wu | 2011 | Acta Biochimica et Biophysica Sinica2011，43，1： | 28 |
| 2 | The epidemiology of norovirus gastroenteritis in China:disease burden and distribution of genotypes显示文摘With the improvements of sanitation and nationwide safe water supply the occurrence of bacterial diarrhea declined remarkably,while viruses became the leading causes of acute gastroenteritis(AGE).Of these viruses,noroviruses(NoVs)are responsible for a considerable burden of gastroenteritis,especially in children<2 years and elderly≥65 years.NoVs circulating in the Chinese population are antigenically highly diverse with the genotype GII.4 being the dominant strain followed by GII.3.Given the widespread contamination in environmental sources,and highly infectious nature of NoVs,vaccination would be the desirable strategy for the control of NoV infections.However,a better understanding of acquired immunity after infection,and a reliable immunological surrogate marker are urgently needed,since two vaccine candidates based on virus-like particles(VLPs)are currently moving into clinical evaluations in China. | Honglu Zhou Songmei Wang Lorenz von Seidlein Xuanyi Wang | 2020 | Frontiers of Medicine2020，14，1： | 28 |
| 3 | Special Section:SARS-CoV-2 Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19显示文摘Effective therapies are urgently needed for the SARS-CoV-2 pandemic.Chloroquine has been proved to have antiviral effect against coronavirus in vitro.In this study,we aimed to assess the efficacy and safety of chloroquine with different doses in COVID-19.In this multicenter prospective observational study,we enrolled patients older than 18 years old with confirmed SARS-CoV-2 infection excluding critical cases from 12 hospitals in Guangdong and Hubei Provinces.Eligible patients received chloroquinephosphate s00 mg,orally,once(half dose)or twice(full dose)daily.Patients treated with non-chloroquine therapy were included as historical controls.The primary endpoint is the time to undetectable viral RNA.Secondary outcomes include the proportion of patients with undetectable viral RNA by day 10 and 14,hospitalization time,duration of fever,and adverse events.A total of 197 patients completed chloroquine treatment,and 176patients were included as historical controls.The median time to achieve an undetectable viral RNA was shorter in chloroquine than in non-chloroquine(absolute difference in medians-6.0 days;95%CI-6.0 to—4.0).The duration of fever is shorter in chloroquine(geometric mean ratio 0.6;95%CIO.5 to 0.8).No serious adverse events were observed in the chloroquine group.Patients treated with half dose experienced lower rate of adverse events than with full dose.Although randomized trials are needed for further evaluation,this study provides evidence for safety and efficacy of chloroquine in COVID-19 and suggests that chloroquine can be a cost-effective therapy for combating the COVID-19 pandemic. | Mingxing Huang Man Li Fei Xiao Pengfei Pang Jiabi Liang Tiantian Tang Shaoxuan Liu Binghui Chen Jingxian Shu Yingying You Yang Li Meiwen Tang Jianhui Zhou Guanmin Jiang Jingfen Xiang Wenxin Hong Songmei He Zhaoqin Wang Jianhua Feng Changqing Lin Yinong Ye Zhilong Wu Yaocai Li Bei Zhong Ruilin Sun Zhongsi Hong Jing Liu Huili Chen Xiaohua Wang Zhonghe Li Duanqing Pei Lin Tian Jinyu Xia Shanping Jiang Nanshan Zhong Hong Shan | 2020 | National Science Review2020，7，9： | 20 |
| 4 | Characterization and Evaluation of OsLCT1 and OsN ramp5 Mutants Generated Through CRISPR/Cas9-Mediated Mutagenesis for Breeding Low Cd Rice显示文摘To explore how rice(Oryza sativa L.) can be safely produced in Cd-polluted soil, OsLCT1 and OsNramp5 mutant lines were generated by CRISPR/Cas9-mediated mutagenesis. One of OsLCT1 mutant(lct1×1) and two of OsNramp5 mutants(nramp5×7 and nramp5×9) were evaluated for grain Cd accumulation and agronomic performances. In paddy field soil containing approximately 0.9 mg/kg Cd, lct1×1 grains contained approximately 40%(0.17 mg/kg) of the Cd concentration of the wild type parental line, less than the China National Food Safety Standard(0.20 mg/kg). Both OsNramp5 mutants showed low grain Cd accumulation(< 0.06 mg/kg) in the paddy(approximately 0.9 mg/kg Cd) or in pots in soil spiked with 2 mg/kg Cd. However, only nramp5×7 showed normal growth and yield, whereas the growth of nramp5×9 was severely impaired. The study showed that lct1×1 could be used to produce rice grains safe for human consumption in lightly contaminated paddy soils and nramp5×7 used in soils contaminated by much higher levels of Cd. | LIU Songmei JIANG Jie LIU Yang MENG Jun XU Shouling TAN Yuanyuan LI Youfa SHU Qingyao HUANG Jianzhong | 2019 | Rice science2019，26，2： | 15 |
| 5 | Effect of temperature on corrosion behavior of 3003 aluminum alloy in ethylene glycol–water solution显示文摘The effect of temperature on the corrosion behavior of 3003 aluminum alloy in ethylene glycol–water solution was investigated by potentiodynamic polarization and electrochemical impedance spectroscopy(EIS) techniques. The surface characterization was observed and determined by scanning electron microscopy(SEM), atomic force microscopy(AFM) and energy dispersive spectrometer(EDS). The results demonstrate that the anodic aluminum dissolution and the cathodic oxygen reduction were accelerated by the increased temperature. However, as temperature was over60 °C, the solubility and concentration of oxygen decreased, resulting in the inhibition of cathodic reaction. The cathodic reaction rate of 3003 aluminum alloy rose to the maximum at 60 °C. The Warburg impedance in Nyquist diagram diminished and then was replaced by a negative capacitance caused by the absorption of intermediate corrosion product on electrode. On the other hand,after potentiodynamic measurements, 3003 aluminum alloy suffered pitting corrosion. The dissolution of aluminum alloy around secondary phase particles expanded both horizontally and vertically. | Chen Xin Tian Wenming Li Songmei Yu Mei Liu Jianhua | 2016 | Chinese Journal of Aeronautics2016，29，4： | 14 |
| 6 | Photoreduction of C02 on BiOCI nanoplates with the assistance of photoinduced oxygen vacancies显示文摘 | Ling Zhang WenzhongWang Dong Jiang Erping Gao Songmei Sun | 2015 | Nano Research2015，8，3： | 13 |
| 7 | An Important Ornithischian Tracksite in the Early Jurassic of the Shenmu Region,Shaanxi,China显示文摘A large track site with multiple, well-preserved trackways of an Early Jurassic quadrupedal ornithischian dinosaur is the first report of Moyenisauripus-like trackways from Asia, herein named Shenmuichnus youngteilhardorum. The tracks occur in a clastic fluvial sequence in the Fuxian Formation in Shenmu County, Shaanxi Province, which is in the same general region as the discovery site of Sinoichnites,the first dinosaur track reported from China. Based on size and morphology, it is likely that Sinoichnites, which is now lost, also represents an ornithischian. The Shenmuichnus youngteilhardorum trackways show two modes of preservation: the first representing deeper tracks, with sediment rims, results in Deltapodus-like tracks, with indistinct pes digit traces and sub-circular manus traces, the second produces Moyenosauripus-like tracks, with clear tridactyl and pentadactyl digit traces in the pes and manus respectively. Thus the Shenmu trackways play a key role in resolving globally significant ichnotaxonomic problems surrounding the nomenclature of Sinoichnites, Moyenosauripus, Deltapodus and other named (Ravatichnus) and unnamed trackways from Asia, Africa and Europe. In addition they shed important light on the paleogeographical and paleoecological distribution of quadrupedal ornithischians in the Early Mesozoic. The track site has been the focus of a major excavation to transfer the trackways from their original remote location to the new Shenmu Museum, in Shenmu City. Other tracksites in the area which reveal Anomoepus, Grallator and the Deltapodus morphotype, together with Shenmuichnus and plant fossil evidence, suggest an Early Jurassic age for the tracksite. | LI Jianjun Martin G.LOCKLEY ZHANG Yuguang HU Songmei MATSUKAWA Masaki BAI Zhiqiang | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 11 |
| 8 | Specific cellular immune responses in mice immunized with DNA,adeno-associated virus and adenoviral vaccines of Epstein-Barr virus-LMP2 alone or in combination显示文摘Cellular immune responses,particularly those associated with CD3+CD8+ cytotoxic T lymphocytes (CTL),are critical factors in controlling viral infection.Nasopharyngeal carcinoma (NPC) is closely associated with persistent Epstein-Barr virus (EBV) infection.NPC vaccine studies have focused on enhancing specific antiviral CTL responses.In this study,three vaccines capable of expressing the EBV-latent membrane protein 2 (LMP2) (a DNA vector,an adeno-associated virus (AAV) vector,and a replication-defective adenovirus serotype 5 (Ad5) vector) were respectively used to immunize female Balb/c mice (4-6 weeks old) at weeks 0,2 and 4,either alone or in combination.Our results suggest that combined immunization with DNA,AAV,and adenovirus vector vaccines induced specific cellular immunity more effectively than any of these vectors alone or a combination of two of the three,constituting a sound vaccine strategy for the prevention and treatment of NPC. | WANG Zhan YANG SongMei ZHOU Ling DU HaiJun MO WuNing ZENG Yi | 2011 | Science China(Life Sciences)2011，54，3： | 10 |
| 9 | High Accurate Interpolation of NURBS Tool Path for CNC Machine Tools显示文摘Feedrate fluctuation caused by approximation errors of interpolation methods has great effects on machining quality in NURBS interpolation, but few methods can efficiently eliminate or reduce it to a satisfying level without sacrificing the computing efficiency at present. In order to solve this problem, a high accurate interpolation method for NURBS tool path is proposed. The proposed method can efficiently reduce the feedrate fluctuation by forming a quartic equation with respect to the curve parameter increment, which can be efficiently solved by analytic methods in real-time. Theoretically, the proposed method can totally eliminate the feedrate fluctuation for any 2nd degree NURBS curves and can interpolate 3rd degree NURBS curves with minimal feedrate fluctuation.Moreover, a smooth feedrate planning algorithm is also proposed to generate smooth tool motion with considering multiple constraints and scheduling errors by an efficient planning strategy. Experiments are conducted to verify the feasibility and applicability of the proposed method. This research presents a novel NURBS interpolation method with not only high accuracy but also satisfying computing efficiency. | LIU Qiang LIU Huan YUAN Songmei | 2016 | Chinese Journal of Mechanical Engineering2016，29，5： | 10 |
| 10 | Bi2WO6 quantum dot-intercalated ultrathin montmo- rillonite nanostructure and its enhanced photocatalytic performance显示文摘在电子洞再结合和水氧化之间的运动比赛是为切开材料的有效的太阳的水的发展的关键限制。在这研究,我们在场由构造量解决这挑战的一个解决方案设置点的 nanostructure。第一次,我们证明设置的 nanostructure 的夹层费用能显著地在光催化禁止电子洞再结合。为双性人<潜水艇class=“ a-plus-plus ”> 2 WO <潜水艇class=“ a-plus-plus ”> 6 个量点( QD )在 montmorillonite ( MMT )设置了 nanostructure 作为一个例子, photogenerated 费用搬运人的平均一生被构造设置的 nanostructure 从 3.06 s 增加到 18.8 s 。增加的一生显著地改进了双性人的 photocatalytic 表演 < 潜水艇 class= “ a-plus-plus ” > 2 WO < 潜水艇 class= “ a-plus-plus ” > 在太阳的水氧化和环境纯化的 6 。这个工作不仅提供一个方法生产设置 QD 的 ultrathin nanostructures 而且一条一般线路为太阳的燃料产生和环境纯化设计有效基于半导体的 photoconversion 材料。 | Songmei Sun Wenzhong Wang Dong Jiang Ling Zhang Xiaoman Li Yali Zheng Qi An | 2014 | Nano Research2014，7，10： | 10 |
| 11 | Downregulation of lncRNA AFAP1-AS1 by oridonin inhibits the epithelial-to-mesenchymal transition and proliferation of pancreatic cancer cells显示文摘Recent studies have demonstrated that the expression of the long non-coding RNA(lncRNA)AFAP1-AS1 in pancreatic cancer is negatively correlated with survival and prognosis.However,the effects of oridonin and lncRNA AFAP1-AS1 on the epithelial-to-mesenchymal transition(EMT)and migration of pancreatic cancer cells have not been fully elucidated.Surgery is the only potentially curative method for pancreatic cancer,but postoperative recurrence and metastasis are common.The aim of the present study was to assess the effect of oridonin and lncRNA AFAP1-AS1 silencing on pancreatic cancer cells.The pancreatic cancer cell lines BxPC-3 and PANC-1 cells were transfected with siAFAP1-AS1 and its negative control(siNC).After that,oridonin was used to treat the siAFAP1-AS1-transfected cells.The expression of lncRNA AFAP1-AS1 was downregulated in the pancreatic cancer cell lines BxPC-3 and PANC-1.The apoptosis and cell cycle progression of pancreatic cancer cells were evaluated by flow cytometry and Hoechst 33258 staining.Metastasis and invasion of BxPC-3 and PANC-1 cells were detected by transwell migration assay,real-time cell analysis,and western blot analysis.Cells were transfected with the lentiviral siAFAP1-AS1 and siNC,and tumorigenesis was evaluated in BALB/C nude mice.Immunohistochemical examination was used to verify the effects of oridonin and siAFAP1-AS1 on pancreatic cancer.The results demonstrated that the combination of oridonin and siAFAP1-AS1 inhibited pancreatic cancer cell proliferation,induced apoptosis,arrested cell cycle progression,prevented the migration,regulated EMT-related protein expression in BxPC-3 and PANC-1 cells,and inhibited pancreatic cancer cell tumorigenicity and EMT in nude mice. | Songmei Lou Jian Xu Bili Wang Shuquan Li Jun Ren Zhengjun Hu Bin Xu Feng Luo | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 10 |
| 12 | Corrosion behavior of an Al-6Mg-Sc-Zr alloy显示文摘The corrosion behavior of an Al-6Mg-Sc-Zr alloy was studied and compared with that of an Al-6Mg-Zr alloy.The addition of scandium into the Al-6Mg-Zr alloy reduced the susceptibility to exfoliation corrosion. By using the constantload tensile method in a 3.5 wt.% NaCl solution, the resistance to SCC of the Al-6Mg-Sc-Zr alloy was higher than that ofthe Al-6Mg-Zr alloy. When the specimens were not applied with an anodic current, the Al-6Mg-Sc-Zr alloy was resistanceto SCC and no brittle cracking was found on the fracture surface. When an anodic current was applied, the Al-6Mg-Sc-Zralloy specimens failed as a result of accelerated corrosion rather than SCC. It was believed that the addition of scandium re-sulted in (Al3Sc, Zr) particles that greatly refined grains and promoted the formation of homogeneous discontinuous distri-bution of β-phase in the alloy base, which much contributed to good corrosion resistance of the Al-6Mg-Sc-Zr alloy. | XU Guangxin TAO Binwu LIU Jianhua LI Songmei | 2005 | Rare Metals2005，24，3： | 8 |
| 13 | Prediction of Dynamic Cutting Force and Regenerative Chatter Stability in Inserted Cutters Milling显示文摘Currently, the modeling of cutting process mainly focuses on two aspects: one is the setup of the universal cutting force model that can be adapted to a broader cutting condition; the other is the setup of the exact cutting force model that can accurately reflect a true cutting process. However, there is little research on the prediction of chatter stablity in milling. Based on the generalized mathematical model of inserted cutters introduced by ENGIN, an improved geometrical, mechanical and dynamic model for the vast variety of inserted cutters widely used in engineering applications is presented, in which the average directional cutting force coefficients are obtained by means of a numerical approach, thus leading to an analytical determination of stability lobes diagram (SLD) on the axial depth of cut. A new kind of SLD on the radial depth of cut is also created to satisfy the special requirement of inserted cutter milling. The corresponding algorithms used for predicting cutting forces, vibrations, dimensional surface finish and stability lobes in inserted cutter milling under different cutting conditions are put forward. Thereafter, a dynamic simulation module of inserted cutter milling is implemented by using hybrid program of Matlab with Visual Basic. Verification tests are conducted on a vertical machine center for Aluminum alloy LC4 by using two different types of inserted cutters, and the effectiveness of the model and the algorithm is verified by the good agreement of simulation result with that of cutting tests under different cutting conditions. The proposed model can predict the cutting process accurately under a variety of cutting conditions, and a high efficient and chatter-free milling operation can be achieved by a cutting condition optimization in industry applications. | LI Zhongqun LIU Qiang YUAN Songmei HUANG Kaisheng | 2013 | Chinese Journal of Mechanical Engineering2013，26，3： | 8 |
| 14 | Surface pollen distribution patterns in Beibu Gulf and corresponding sediment dynamics environment显示文摘The Beibu Gulf is a semi-enclosed gulf in the northwest of the South China Sea.We palynologically analyzed 306 surface sediment samples from the eastern Beibu Gulf to improve bioclimatic interpretation of fossil pollen records there.Surface pollen assemblages could be classified into five pollen regions based on the distributions of total,arboreal,herbaceous and fern pollen concentrations.Four high-concentration and three low-concentration subregions could be distinguished within these regions.The distribution patterns of surface pollen assemblages were consistent with those of grain sizes of surface sediments.Sediments from regions with high pollen concentrations were very fine and fine silts (>7.0,<0.008 mm),whereas those with low pollen concentrations were fine sand (<3.5,>0.088 mm).Sedimentary heterogeneity of surface pollen assemblages was closely related to pollen source,transportation and sedimentation controlled by ocean currents,tides and waves,and oceanic bottom topography.Fern spores exhibited higher percentages along the east margins of the region,while arboreal types like Pinus increased in concentration towards the center.Herbaceous pollen appeared in high percentages around seacoasts near their source areas.Dacrydium and mangrove pollen were distributed near their source regions at low percentages.We discuss the sediment dynamic environments in the eastern Beibu Gulf based on surface pollen distributions.The estuary region is an important access to the sea basin and a depositional site for terrestrial pollen grains.Coastal regions can accumulate pollen due to the back-and-forth movements of tides there.Although ocean currents on a gulf scale tend to spread pollen grains,the interaction of multiple currents could lead to pollen accumulation and deposition.Low surface pollen concentrations in the northeast shallow-water regions of the eastern Beibu Gulf could be attributed to repeated washing and sediment floatation caused by severe wave activities during the summer.Strong tides in Qiongzhou Strait frequently wash the seabed and disadvantage pollen deposition,leading to low surface pollen concentrations there. | TONG GuoBan CHEN Lian LONG JiangPing LI TuanJie XIAO XiaYun TONG SongMei | 2012 | Chinese Science Bulletin2012，57，8： | 8 |
| 15 | Preparation and characterization of the TiO_2-V_2O_5 photocatalyst with visible-light activity显示文摘Visible-light responsive TiO2-V2O5 catalyst was prepared using a binary sol-gel and in-situ intercalation method. The TiO2 sol and V2O5 sol were mixed to disperse the V2O5 species in the TiO2 phase at molecular level. The binary sol was then intercalated into interspaces of polyaniline (PANI) by means of in-situ polymerization of aniline. Conglomeration of the TiO2-V2O5 clusters during the calcination process was avoided because of the wrap of polyaniline. The surface mor- phology, the crystal phases, the structure, and the absorption spectra of (PANI)n/TiO2-V2O5 and the composite catalyst were studied using SEM, XRD, FT-IR, and UV-Vis. The photoactivity of the prepared catalyst under UV and visible light irra- diation were evaluated by decolorization of methylene blue (MB) solution. The results showed that the composite catalyst displayed a homogeneous anatase phase, and the vanadium pentoxide species was highly dispersed in the TiO2 phase. The composite catalyst responded to visible light because of the narrowed band gap. In this study, the catalyst with the sol vol- ume ratio of TiO2 : V2O5 = 10:1 presented the best photocatalytic activity. | LIU Jianhua YANG Rong LI Songmei | 2006 | Rare Metals2006，25，6： | 7 |
| 16 | Preparation of bimodal grain size 7075 aviation aluminum alloys and their corrosion properties显示文摘The bimodal grain size metals show improved strength and ductility compared to traditional metals; however, their corrosion properties are unknown. In order to evaluate the corrosion properties of these metals, the bimodal grain size 7075 aviation aluminum alloys containing different ratios of coarse(100 μm in diameter) and fine(10 μm in diameter) grains were prepared by spark plasma sintering(SPS). The effects of grain size as well as the mixture degree of coarse and fine grains on general corrosion were estimated by immersion tests, electrochemical measurements and complementary techniques such as scanning electron microscope(SEM) and transmission electron microscope-energy disperse spectroscopy(TEM-EDS). The results show that, compared to fine grains, the coarse grains have a faster dissolution rate in acidic NaCl solution due to the bigger size,higher alloying elements content and larger area fraction of second phases in them. In coarse grains,the hydrogen ions have a faster reduction rate on cathodic second phases, therefore promoting the corrosion propagation. The mixture of coarse and fine grains also increases the electrochemical heterogeneity of alloys in micro-scale, and thus the increased mixture degree of these grains in metal matrix accelerates the corrosion rate of alloys in acidic NaCl solution. | Wenming TIAN Songmei LI Jianhua LIU Mei YU Yujie DU | 2017 | Chinese Journal of Aeronautics2017，30，5： | 7 |
| 17 | SKP2 siRNA inhibits the degradation of P27^kip1 and down-regulates the expression of MRP in HL-60/A cells显示文摘S 阶段联系 kinase 的蛋白质 2 (SKP2 ) 基因是肿瘤 suppressor 基因,并且涉及 P27kip1 的调停 ubiquitin 的降级。SKP2 和 P27kip1 影响通过调整白血病房间的增长, apoptosis 和区别继续和白血病的预后。在这研究,我们探索了通过 SKP2 下面规定 HL-60/A 药抵抗逆行的机制。HL-60/A 房间是由有 SKP2 siRNA 的 Amaxa Nucleofector 系统的 nucleofected。Skp2, P27kip1,和多药抵抗的基因和蛋白质表示层次联系了蛋白质(MRP ) 被反向的抄写聚合酶链反应和西方的污点分析分别地决定。房间周期被流动 cytometry 分析。50% 禁止的集中价值在 chemotherapeutics 的不同集中下面根据这些二种房间的死亡率用细胞毒素的分析被计算比较房间的敏感。HL-60/A 房间显示出由抗力移转特征的多药抵抗显型到 adriamycin, daunorubicin,和 arabinosylcytosine,由于 MRP 的表示。我们发现 SKP2 的表示比在 HL-60 房间在 HL-60/A 房间是更高的,但是 P27kip1 的表示更低。而 P27kip1 的蛋白质水平是起来调整的,在由 SKP2 siRNA 的 HL-60/A 房间 nucleofected 的 SKP2 的表示是下面调整的。与在控制组(由控制 siRNA 的 nucleofected ) 的 MRP 表达式水平相比, mRNA 和蛋白质表达式由 SKP2 siRNA 在 HL-60/A 房间 nucleofected MRP 铺平更低,并且后者房间对 adriamycin, daunorubicin,和 arabinosylcytosine 更敏感。下面调整在 G0/G1 阶段的 SKP2 表示和逮捕房间与下面调整的 MRP 改进白血病房间的药敏感表示。 | Jie Xiao Songmei Yin Yiqing Li Shuangfeng Xie Danian Nie Liping Ma Xiuju Wang Yudan Wu Jianhong Feng | 2009 | Acta Biochimica et Biophysica Sinica2009，41，8： | 7 |
| 18 | Fabrication and characterization of highly ordered Ni_(0.5)Zn_(0.5)Fe_2O_4 nanowire/tube arrays by sol-gel template method显示文摘Highly ordered nanowire/tube arrays of Ni0.5Zn0.5Fe2O4 were fabricated by the sol-gel method in the pores of anodic alu- mina membrane (AAM). Whether nanowires or nanotubes were fabricated depends on immersion time. The immersion time was 15-40 s for nanotubes and over 60 s for nanowires. The topography and crystalline structure of the nanowire arrays were character- ized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray diffraction (XRD). It was found that the length and diameter of the Ni0.5Zn0.5Fe2O4 nanowires are related to the thickness of the AAM and the diameter of the pores. The results indicated that the Ni0.5Zn0.5Fe2O4 nanowires are uniform and parallel to each other. | Mei Yu Jianhua Liu Songmei Li | 2007 | Journal of University of Science and Technology Beijing2007，14，5： | 6 |
| 19 | Preparation and characterization of high photoactive TiO_2 catalyst using the UV irradiation-induced sol-gel method显示文摘High photoactive TiO2 catalyst was prepared using the sol-gel method through UV irradiation during the formation stage of nuclei. The surface morphology and microstructure of the prepared catalyst were characterized using scanning electron microscopy (SEM), X-ray diffraction patterns (XRD), and Fourier transform infrared spectroscopy (FT-IR). The photoactivity was evaluated by the degradation of methylene blue. The results show that the photocatalysis of the prepared catalyst is higher than that of conventional heat-treated particles. The higher photoactivity is a combined result of favorable microstructure, appropriate hydroxyl groups, and active sites of Ti3+ ions on the surface of TiO2. It is concluded that the ultraviolet irradiation-induced sol-gel method is an effective method to enhance the photocatalysis of TiO2. | Jianhua Liu Rong Yang Songmei Li | 2006 | Journal of University of Science and Technology Beijing2006，13，4： | 4 |
| 20 | Influence of Minimum Quantity Lubrication Parameters on Tool Wear and Surface Roughness in Milling of Forged Steel显示文摘The minimum quantity of lubrication(MQL) technique is becoming increasingly more popular due to the safety of environment.Moreover,MQL technique not only leads to economical benefits by way of saving lubricant costs but also presents better machinability.However,the effect of MQL parameters on machining is still not clear,which needs to be overcome.In this paper,the effect of different modes of lubrication,i.e.,conventional way using flushing,dry cutting and using the minimum quantity lubrication(MQL) technique on the machinability in end milling of a forged steel(50CrMnMo),is investigated.The influence of MQL parameters on tool wear and surface roughness is also discussed.MQL parameters include nozzle direction in relation to feed direction,nozzle elevation angle,distance from the nozzle tip to the cutting zone,lubricant flow rate and air pressure.The investigation results show that MQL technique lowers the tool wear and surface roughness values compared with that of conventional flood cutting fluid supply and dry cutting conditions.Based on the investigations of chip morphology and color,MQL technique reduces the cutting temperature to some extent.The relative nozzle-feed position at 120°,the angle elevation of 60° and distance from nozzle tip to cutting zone at 20 mm provide the prolonged tool life and reduced surface roughness values.This fact is due to the oil mists can penetrate in the inner zones of the tool edges in a very efficient way.Improvement in tool life and surface finish could be achieved utilizing higher oil flow rate and higher compressed air pressure.Moreover,oil flow rate increased from 43.8 mL?h to 58.4 mL?h leads to a small decrease of flank wear,but it is not very significant.The results obtained in this paper can be used to determine optimal conditions for milling of forged steel under MQL conditions. | YAN Lutao YUAN Songmei LIU Qiang | 2012 | Chinese Journal of Mechanical Engineering2012，25，3： | 4 |
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