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| 1 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 2 | Management of gastric cancer in Asia: resource-stratified guidelines显示文摘 | Lin Shen Yan-Shen Shan Huang-Ming Hu Timothy J Price Bhawna Sirohi Kun-Huei Yeh Yi-Hsin Yang Takeshi Sano Han-Kwang Yang Xiaotian Zhang Sook Ryun Park Masashi Fujii Yoon-Koo Kang Li-Tzong Chen | 2013 | Lancet Oncology2013，，12： | 5 |
| 3 | Polyethylene glycol-coated liposomes for oral delivery of recombinant human epidermal growth factor显示文摘 | Song LH Park JH Sook J | 2003 | lnt J Pharm2003，258，12： | 1 |
| 4 | Cloning of prophenoloxidase from hemocytes of the blue crab, Callinectes sapidus and its expression and enzyme activity during the molt cycle 显示文摘 | Alvarez Javier V Sook Chung J | 2013 | Fish & Shellfish Immunology2013，35，： | 1 |
| 5 | Cloning of prophenoloxidase from hemocytes of the blue crab, Callinectes sapidus and its expression and enzyme activity during the molt cycle 显示文摘 | Alvarez Javier V Sook Chung J | 2013 | Fish & Shellfish Immunology2013，35，： | 1 |
| 6 | Cure characteriza-tion in bis(maleimide) / diallylbisphenol a resin by fluorescence,FT-IR, and UV-reflection spectroscopy显示文摘 | Phelan J C Chong Sook Paik Sung | 1997 | Macromolecules1997，30，： | 1 |
| 7 | Molecular characterization of antimicrobial resistance in Shigella sonnei isolates in Korea显示文摘 | Sung YS Yong TK Young Sook J | 2006 | J Med Microbiol2006，55，7： | 1 |
| 8 | Inclusion Complex of Conjugated Linoleic Acid (CLA) with Cyclodextrins 显示文摘 | Cherl W P Seck J K Sook J P | 2002 | Agric Food Chem2002，50，10： | 1 |
| 9 | Novel miniature SPR immunosensor equipped with all- in-one multi-microehannel sensor chip for detecting low- molecular-weight analytes 显示文摘 | SOOK J K K VENGATAJALABATHY G HIROYUKI I | 2007 | Biosensors and Bioeleetronics2007，23，： | 1 |
| 10 | Endothelial dysfunction and increased carotid intima-media thickness in the patients with slow coronary flow显示文摘 | Hyun JY Myung H J Sook HC | 2012 | J Korean Med Sci2012，27，6： | 1 |
| 11 | 显示文摘 | Jaephil C Sook J H Chul P Y | 2000 | J Elctrochem Soc2000，147，： | 1 |
| 12 | A second copper zinc superoxide dismutase(CuZnSOD)in the blue crab Callinectes sapidus:cloning and up-regulated expression in the hemocytes after immune challenge显示文摘 | Sook Chung J Bachvaroff T R Trant J | 2012 | Fish&Shellfish Immunology2012，32，1： | 1 |
| 13 | Ant i-invasive activity of soli e and correalat es w i th the reduced exp ressi on of mat rix met al loproteninase-9 (M M P-9)in HT-1080 human fibro-sarcoma cell s显示文摘 | Hee J Sook B Ho Y | 1996 | Cancer Res1996，56，： | 1 |
| 14 | A longitudinal study of oralural ulcerative mucositis in bune marrow transplant recipients 显示文摘 | Sook Bin W Wardley J Michacl M | 1993 | Cancer1993，72，5： | 1 |
| 15 | Kinetics and mechanisms for thermal imidization of a polyamic acid studied by ultraviolet - visible spectroscopy 显示文摘 | Eumi Pyun Richard J Mathisen Chong Sook Paik Sung | 1989 | Macromolecules1989，22，3： | 1 |
| 16 | Thromboxane A2 synthetase inhibitor plus low dose aspirin: can it be a salvage treatment in acute stroke beyond thrombolytic time window 显示文摘 | Gyu HA Sook YS Cheol S J | 2011 | J Korean Neurosurg S2011，50，1： | 1 |
| 17 | Cure characterization in bis (maleimide)/diallylbisphenol a resin by fluorescence, FT-IR and UV-reflection spectroscopy显示文摘 | PHELAN J C SUNG CHONG SOOK PAIK | 1997 | Macromolecules1997，30，22： | 1 |
| 18 | Kinetics and mechanisms for thermal imidization of a polyamic acid studied by ultraviolet-visible spectroscopy显示文摘 | Eumi Pyun Richard J Mathisen Chong Sook Paik Sung | 1989 | Macromolecules1989，22，3： | 1 |
| 19 | Influence of Dispersion States of Carbon Nanotubes on Physical Properties of Epoxy Nanocomposites显示文摘 | S Y Sook J R Youn | 2005 | Carbon2005，43，： | 1 |
| 20 | Effects of Fomes fomentarius supplementation on antioxidant enzyme activities,blood glucose,and lipid profile in streptozotocininduced diabetic rats显示文摘 | SOOK L J | 2005 | Nutrition Research2005，25，2： | 1 |
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