|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of surgical resection for multiple hepatocellular carcinomas显示文摘AIM:To clarify the role of surgical resection for multiple hepatocellular carcinomas(HCCs)compared to transarterial chemoembolization(TACE)and liver transplantation(LT). METHODS:Among the HCC patients who were managed at Yonsei University Health System between January 2003 and December 2008,160 patients who met the following criteria were retrospectively enrolled:(1) two or three radiologically diagnosed HCCs;(2)no radiologic vascular invasion;(3)Child-Pugh class A;(4) main tumor smaller than 5 cm in diameter;and(5) platelet count greater than 50 000/mm3.Long-term outcomes were compared among the following three treatment modalities:surgical resection or combined radiofrequency ablation(RFA)(n=36),TACE(n=107), and LT(n=17).The survival curves were computed using the Kaplan-Meier method and compared with a log-rank test.To identify the patients who gained a survival benefit from surgical resection,we also investigated prognostic factors for survival following surgical resection.Multivariate analyses of the prognostic factors for survival were performed using the Cox proportional hazard model. RESULTS:The overall survival(OS)rate was significantly higher in the surgical resection group than in the TACE group(48.1%vs 28.9%at 5 years,P<0.005). LT had the best OS rate,which was better than that of the surgical resection group,although the difference was not statistically significant(80.2%vs 48.1%at 5 years,P=0.447).The disease-free survival rates were also significantly higher in the LT group than in the surgical resection group(88.2%vs 11.2%at 5 years, P<0.001).Liver cirrhosis was the only significant prognostic factor for poor OS after surgical resection. Clinical liver cirrhosis rates were 55.6%(20/36)in the resection group and 93.5%(100/107)in the TACE group.There were 19 major and 17 minor resections. En bloc resection was performed in 23 patients,multisite resection was performed in 5 patients,and combined resection with RFA was performed in 8 patients. In the TACE group,only 34 patients(31.8%)were recorded as having complete remission after primary TACE.Seventy-two patients(67.3%)were retreated with repeated TACE combined with other therapies. In patients who underwent surgical resection,the 16 patients who did not have cirrhosis had higher 5-year OS and disease-free survival rates than the 20 patients who had cirrhosis(80.8%vs 25.5%5-year OS rate, P=0.006;22.2%vs 0%5-year disease-free survival rate,P=0.048).Surgical resection in the 20 patients who had cirrhosis did not provide any survival benefit when compared with TACE(25.5%vs 24.7%5-year OS rate,P=0.225).Twenty-nine of the 36 patients who underwent surgical resection experienced recur-rence.Of the patients with cirrhosis,80%(16/20) were within the Milan criteria at the time of recurrence CONCLUSION:Among patients with two or three HCCs, no radiologic vascular invasion,and tumor diameters≤ 5 cm,surgical resection is recommended only in those without cirrhosis. | Sung Hoon Choi Gi Hong Choi Seung Up Kim Jun Yong Park Dong Jin Joo Man Ki Ju Myoung Soo Kim Jin Sub Choi Kwang Hyub Han Soon Il Kim | 2013 | World Journal of Gastroenterology2013，19，3： | 12 |
| 2 | Histological improvement following administration of autologous bone marrow‐derived mesenchymal stem cells for alcoholic cirrhosis: a pilot study显示文摘 | Yoon Ok Jang Young Ju Kim Soon Koo Baik Moon Young Kim Young Woo Eom Mee Yon Cho Hong Jun Park So Yeon Park Bo Ra Kim Jae Woo Kim Hyun Soo Kim Sang Ok Kwon Eun Hee Choi Yong Man Kim | 2014 | Liver Int2014，，1： | 2 |
| 3 | Polymer Journal显示文摘 | | 1991 | 371991，37，： | 1 |
| 4 | Structure Development during Flow of Ternary Blends of a Polyamide (Nylon46), a Thermotropic Liquid Crystal- line Polymer E Poly ( ester amide) 1, and a Thermoplastic Elastomer (EPDM) 显示文摘 | Yongsok Seo Soon Man Hong Kwang Ung Kim | 1997 | Macromolecules1997，30，： | 1 |
| 5 | Synthesis and curing of liquid crystalline epoxy resins based on 4,4' -biphenol显示文摘 | Jun Yeob Lee Jyongsik Jang Seung Sang Hwang Soon Man Hong Kwang Ung Kim | 1998 | Polymer1998，39，24： | 1 |
| 6 | Structure development during flow of ternary blends of a polyamide (ntlon 46),a thermotropic liquid crystalline polymer (poly (ester amide)),and a thermoplastic elastomer (EPDM)显示文摘 | SOON MAN HONG KWANG UNG KIM | 1997 | Macromolecules1997，30，： | 1 |
| 7 | Synthesis and curing of liquid crystalline epoxy resins based on 4,4'-biphenol显示文摘 | Jun Yeob Lee Jyongsik Jang Seung Sang Hwang Soon Man Hong and Kwang Ung Kim | 1998 | Polymer1998，39，24： | 1 |
| 8 | The morphology and properties of ternary blends of polyamides, a thermotropic liquid crystalline polymer and a compatibilizer显示文摘 | Yongsok Seo Byeongyeol Kim Seung Sang Hwang Soon Man Hong Kwang Ung Kim | 2000 | Composite Interfaces2000，，3： | 1 |
| 9 | Poly(ethylenedioxythiophene) (PEDOT) as polymer electrode in redox supercapacitor显示文摘 | Kwang Sun Ryu Young-Gi Lee Young-Sik Hong Yong Joon Park Xianlan Wu Kwang Man Kim Man Gu Kang Nam-Gyu Park Soon Ho Chang | 2004 | Electrochimica Acta2004，，2： | 1 |
| 10 | Effects of Aerobic Exercise Training on C1q Tumor Necrosis Factor α-Related Protein Isoform 5 (Myonectin): Association with Insulin Resistance and Mitochondrial DNA Density in Women显示文摘 | Soo Lim Sung Hee Choi Bo Kyung Koo Seon Mee Kang Ji Won Yoon Hak Chul Jang Soon Mi Choi Man Gyoon Lee Wan Lee Hayley Shin Young-Bum Kim Hong Kyu Lee Kyong Soo Park | 2012 | The Journal of Clinical Endocrinology & Metabolism2012，，1： | 1 |
| 11 | 显示文摘 | Sangmook Lee Soon Man Hong Yongsok Seo | 1994 | Polymer1994，35，3： | 1 |
| 12 | Structure Development during Flow of Ternary Blends of a Polyamide(Nylon 46 ), a Thermotropic Liquid Crystalline Polymer(Poly (ester amide)), and a Thermoplastic Elastomer(EPDM) 显示文摘 | Yongsok Seo Soon Man Hong Kwang Ung Kin | 1997 | Macromolecures1997，30，： | 1 |
| 13 | Structure Development during Flow of Ternary Blends of a Polyamide (Nylon 46), a Thermotropic Liquid Crystalline Polymer (Poly(ester amide)), and a Thermoplastic Elastomer (EPDM)显示文摘 | Yongsok Se Soon Man Hong Kwang Ung Kim | 1997 | Macromolecules1997，30，： | 1 |
| 14 | Synthesis and curing of liquid crystalline epoxy resins based on 4,4′-biphenol显示文摘 | Jun Yeob Lee Jyongsik Jang Seung Sang Hwang Soon Man Hong Kwang Ung Kim | 1998 | Polymer1998，，24： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员