|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Clinically detected gastroenteropancreatic neuroendocrine tumors are on the rise: Epidemiological changes in Germany显示文摘AIM:To study the epidemiologic changes of gastroenteropancreatic neuroendocrine tumors(GEP-NET)in Germany,we analyzed two time periods 1976-1988 and1998-2006.METHODS:We evaluated epidemiological data of GEP-NET from the former East German National Cancer Registry(DDR Krebsregister,1976-1988)and its successor,the Joint Cancer Registry(GKR,1998-2006),which was founded after German reunification.Due to a particularly substantial database the epidemiological data from the federal states of Mecklenburg-Western Pomerania,Saxony,Brandenburg and Thuringia,covering a population of more than 10.8 million people,were analyzed.Survival probabilities were calculated using life table analysis.In addition,GEP-NET patients were evaluated for one or more second(non-GEP-NET)primary malignancies.RESULTS:A total of 2821 GEP neuroendocrine neoplasms were identified in the two registries.The overall incidence increased significantly between 1976 and2006 from 0.31(per 100.000 inhabitants per year)to2.27 for men and from 0.57 to 2.38 for women.In the later period studied(2004-2006),the small intestine was the most common site.Neuroendocrine(NE)neoplasms of the small intestine showed the largest absolute increase in incidence,while rectal NE neoplasms exhibited the greatest relative increase.Only the incidence of appendiceal NET in women showed little change between 1976 and 2006.Overall survival of patients varied for sex,tumor site and the two periods studied but improved significantly over time.Interestingly,about 20%of the GEP-NET patients developed one or more second malignancies.Their most common location was the gastrointestinal tract.GEP-NET patients without second malignancies fared better than those with one or more of them.CONCLUSION:The number of detected GEP-NET increased about 5-fold in Germany between 1976 and2006.At the same time,their anatomic distribution changed,and the survival of GEP-NET patients improved significantly.Second malignancies are common and influence the overall survival of GEP-NET patients.Thus,GEP-NET warrant our attention as well as intensive research on their tumorigenesis. | Hans Scherübl Brigitte Streller Roland Stabenow Hermann Herbst Michael Hopfner Christoph Schwertner Joachim Steinberg Jan Eick Wanda Ring Krishna Tiwari Soren M Zappe | 2013 | World Journal of Gastroenterology2013，19，47： | 16 |
| 2 | Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma显示文摘 | Stabenow E Tavares MR Ab' Saber AM | 2005 | Clinics2005，60，3： | 1 |
| 3 | Hexxarylcyclotripumbane:A Molecule with a Homonuclear Ring System of Lead 显示文摘 | F Stabenow W Saak H Marsmann | 2003 | J Am Chem Soc2003，125，34： | 1 |
| 4 | Site- and gender-specific time trend analyses of the incidence of skin melanomas in the former German Democratic Republic (GDR) including 19351 cases 显示文摘 | Stang A Stabenow R Eisinger B | 2003 | Eur J Cancer2003，39，11： | 1 |
| 5 | Tumor thickness as a predictive factor of lymph node metastasis and disease recurrence in T1N0 and T2N0 squamous cell carcinoma of the oral tongue显示文摘 | Leandro Luongo de Matos Gabriel Manfro Ricardo Vieira dos Santos Elaine Stabenow Evandro Sobroza de Mello Venancio Avancini F. Alves Fábio Roberto Pinto Marco Aurélio Vamondes Kulcsar Lenine Garcia Brand?o Cláudio Roberto Cernea | 2014 | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology2014，，： | 1 |
| 6 | Mechanisms balancing tolerance and immunity in the liver显示文摘 | B6ttcher JP Knolle PA Stabenow D | 2011 | Dig Dis2011，29，4： | 1 |
| 7 | Site-and gender-specifictime trend analyses of the incidence of skin melanomas in theformer German Democratic Republic (GDR) including 1935 1cases显示文摘 | Stang A Stabenow R Eisinger B | 2003 | Eur JCancer2003，39，11： | 1 |
| 8 | Stress whitening and yield ing mechanism of rubber modified PVC显示文摘 | Breuer H Haaf F Stabenow J | 1977 | J Macromol Sci Phys1977，14，3： | 1 |
| 9 | Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma显示文摘 | Stabenow E Tavares MR Ab Saber AM | 2005 | Clinics (Sao Paulo)2005，60，3： | 1 |
| 10 | Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma显示文摘 | Stabenow E Tavares MR Ab'Saber AM | 2005 | Clinics2005，60，3： | 1 |
| 11 | Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma显示文摘 | STABENOW E TAVARES M R AB'SABER A M | 2005 | Clinics2005，60，3： | 1 |
| 12 | A mouse model of lethal infection for evaluating prophylactics and therapeutics against monkeypox virus 显示文摘 | Stabenow J Buller RM Schriewer J | 2010 | J Virol2010，84，8： | 1 |
| 13 | Angiogenesis as an indicator of metastatic potential in papillary thyroid carcinoma 显示文摘 | Stabenow E Tavares MR Ab'saber AM etal | 2005 | Clinics (Sao Paulo Brazil)2005，60，3： | 1 |
| 14 | Hexxary- leyclotripumbane:A Molecule with a Homonuclear Ring System of Lead显示文摘 | Stabenow F Saak W Marsman H | 2003 | J Am Chem Soc2003，123，34： | 1 |
| 15 | Systemic antigen cross‐presented by liver sinusoidal endothelial cells induces liver‐specific CD8 T‐cell retention and tolerization显示文摘 | Nanette von Oppen Anna Schurich Silke Hegenbarth Dirk Stabenow Rene Tolba Ralf Weiskirchen Albert Geerts Waldemar Kolanus Percy Knolle Linda Diehl | 2009 | Hepatology2009，，5： | 1 |
| 16 | Mechanisms balancing tolerance and immunity in the liver显示文摘 | Botteher JP1 Knolle PA Stabenow D | 2011 | DigDis2011，29，4： | 1 |
| 17 | Bioluminescence imag- ing allows measuring CD8 T cell function in the liver显示文摘 | Stabenow D Frings M Track C | 2010 | Hep- atology2010，1，： | 1 |
| 18 | Stress whitening and yield ing mechanism of rubber modified PVC 显示文摘 | Breuer H Haaf F Stabenow J J | 1977 | Macromol Sci Phys1977，14，3： | 1 |
| 19 | Radiofrequency for benign and malign thyroid lesions显示文摘Background:Thermal ablation of thyroid nodules is new modality for the management of the benign and malign lesions.This minimally invasive treatment is performed as an outpatient,local anesthetic,single professional procedure that can treat neoplastic lesions without removing normal thyroid tissue and thus avoiding hypothyroidism.Method:A comprehensive review of the most relevant literature regarding the thermal ablation of benign and malign nodules was performed in order to currently define its role on the management of the nodular thyroid disease.The data was divided into benign and malign literature.Results:The benign nodules can be effectively treated by radiofrequency ablation(RFA)but some limitation exists regarding the nodule’s size but not nodules characteristics.The RFA of primary malign tumors of the thyroid recently demonstrated positive and safe long-term follow-up and encouraged additional investigation and possibly a definitive role in the management of these low risk nodules.Conclusion:RFA is a safe,cost-effective minimally invasive procedure that avoids thyroid tissue removal while destroying neoplastic one thus,preventing hypothyroidism. | Leonardo Rangel Leonardo M.Volpi Elaine Stabenow Jose Higino Steck Erivelto Volpi Jonathon O.Russell Ralph P.Tufano | 2020 | World Journal of Otorhinolaryngology-Head and Neck Surgery2020，6，3： | 1 |
| 20 | Unexplained inversion of the incidence ratio of colon and rectal cancer among men in East Germany. A time trend analysis including 147,790 cases显示文摘 | Andreas Stang Roland Stabenow Christa Stegmaier Bettina Eisinger Edeltraud Bischof-Hammes Karl-Heinz J?ckel | 2007 | European Journal of Epidemiology2007，，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员