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| 1 | Hedge fund return sensitivity to global liquidity显示文摘 | Stephan Kessler Bernd Scherer | 2010 | Journal of Financial Markets2010，，2： | 1 |
| 2 | Perilesional Blood Flow and Edema Formation in Acute Intracerebral Hemorrhage: A SPECT Study显示文摘 | Stephan A. Mayer Angela Lignelli Matthew E. Fink Deborah B. Kessler Carole E. Thomas Rupendra Swarup Ronald L. Van Heertum | 1998 | Stroke: A Journal of Cerebral Circulation1998，，9： | 1 |
| 3 | Rapid chromatographic method to decipher distinct alterations in lipid classes in NAFLD/NASH显示文摘AIM: To establish a simple method to quantify lipid classes in liver diseases and to decipher the lipid profile in p62/IMP2-2/IGF2BP2-2 transgenic mice.METHODS: Liver-specific overexpression of the insulin-like growth factor 2 mRNA binding protein p62/IMP2-2/IGF2BP2-2 was used as a model for steatosis.Steatohepatitis was induced by feeding a methioninecholine deficient diet. Steatosis was assessed histologically. For thin layer chromatographic analysis, lipids were extracted from freeze-dried tissues by hexane/2-propanol, dried, redissolved, and chromatographically separated by a two-solvent system. Dilution series of lipid standards were chromatographed, detected, andquantified. The detection was performed by either2',7'-dichlorofluoresceine or a sulfuric acid/ethanol mixture.RESULTS: Histological analyses confirmed steatosis and steatohepatitis development. The extraction,chromatographic, and detection method showed high inter-assay reproducibility and allowed quantification of the different lipid classes. The analyses confirmed an increase of triglycerides and phosphatidylethanolamine and a decrease in phosphatidylcholine in the methionine-choline deficient diet. The method was used for the first time to asses the lipid classes induced in the p62-overexpressing mouse model and showed a significant increase in all detected lipid species with a prominent increase of triglycerides by 2-fold. Interestingly, the ratio of phosphatidylcholine to phosphatidylethanolamine was decreased, as previously suggested as a marker in the progression from steatosis to steatohepatitis.CONCLUSION: The thin layer chromatography analysis allows a reliable quantification of lipid classes and provides detailed insight into the lipogenic effect of p62. | Stephan Laggai Yvette Simon Theo Ranssweiler Alexandra K Kiemer Sonja M Kessler | 2013 | World Journal of Hepatology2013，5，10： | 1 |
| 4 | Outcome in neonates with necrotizing enterocolitis and patent ductus arteriosus显示文摘Background:There is no agreement of the influence of patent ductus arteriosus(PDA)on outcomes in patients with necrotizing enterocolitis(NEC).In this study,we assessed the infl uence of PDA on NEC outcomes.Methods:A retrospective study of 131 infants with established NEC was performed.Outcomes(death,disease severity,need for surgery,hospitalization duration),as well as multiple clinical parameters were compared between NEC patients with no congenital heart disease(n=102)and those with isolated PDA(n=29).Univariate,multivariate and stepwise logistic regression analyses were performed.Results:Birth weight and gestational age were significantly lower in patients with PDA[median(95%CI):1120 g(1009-1562 g),28.4 wk(27.8-30.5 wk)]than in those without PDA[median(95%CI):1580 g(1593-1905 g),32.4 wk(31.8-33.5 wk);P<0.05].The risk of NEC-attributable fatality was higher in NEC patients with PDA(35%)than in NEC patients without PDA(14%)[univariate odds ratio(OR)=3.3,95%CI:1.8-8.6,P<0.05;multivariate OR=2.4,95%CI:0.82-2.39,P=0.111].Significant independent predictors for nonsurvival within the entire cohort were advanced disease severity stage III(OR=27.9,95%CI:7.4-105,P<0.001)and birth weight below 1100 g(OR=5.7,95%CI:1.7-19.4,P<0.01).Conclusions:In patients with NEC,the presence of PDA is associated with an increased risk of death.However,when important differences between the two study groups are controlled,only birth weight and disease severity may independently predict mortality. | Ulf Kessler Franzisca Schulte Dietmar Cholewa Mathias Nelle Stephan C.Schaefer Peter M.Klimek Steffen Berger | 2016 | World Journal of Pediatrics2016，12，1： | 0 |
| 5 | A comparative study on design standards of screw conveyors in China,Germany and the USA-PartⅠ:Theoretical calculation and quantitative analysis显示文摘Screw conveyors,widely used devices for transporting bulk materials,play an irreplaceable role in the modern industrial system.Despite of their traditional advantages,designers of screw conveyors still heavily rely on their own country's experiments and standards,which are closely related to empirical data.Therefore,the same conveying task often results in different designs.This work aims to compare the design standards of screw conveyors in China,Germany and the USA.Based on related standards acquired from renowned associations in the three countries,the similarities and particularities of these design guidances are compared.With preforming the geometrical and operational designs for horizon-tal,slightly inclined and vertical conveyance of three representative bulk solids(barley,lignite,sand),the advantages and disadvantages of these semi-empirical designs are comprehensively presented.Fur-thermore,the potential influence of empirical coefficients,which are not explicitly documented,are extensively discussed.By analysing all outcomes,the compatibility and applicability of each standard are qualitatively assessed. | Yuan Tan Michael Rackl Weijie Yang Johannes Fottner Wenjun Meng Stephan Kessler | 2022 | Particuology2022，20，10： | 0 |
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