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| 1 | 单克隆抗体免疫亲和层析法纯化人的凝血因子Ⅸ显示文摘本文报告一种对连接钙(或镁)离子的因子Ⅸ(FⅨ)之构型具有特异性的单克隆抗体(MAb),并将其偶联Affi-Gel 15凝胶,组成亲和层析柱.将钙(或镁)离子加入含有FⅨ的原料液内,混合液流进层析柱时,唯独FⅨ被吸附,而且易被不含钙(或镁)离子的缓冲液洗脱.如洗脱液内含1 mM EDTA,则FⅨ洗脱峰十分陡峭.1 ml凝胶能吸附0.1mg的FⅨ,其吸附容量是理论容量的8%.FⅨ制品比活性为140~180活性单位/mg蛋白.在还原和非还原的SDS-PAGE电泳图谱上呈现一条谱带.此方法快速,且仅需一步即可从人血浆内提取纯化10000倍的FⅨ. | 王海龄 耿力 丁卫 肖小璞 Steiner J Battey F Strickland D | 1989 | 中国输血杂志1989，2，3： | 6 |
| 2 | 2型糖尿病合并肢体部分性脂肪萎缩:一种新的脂肪萎缩表型显示文摘脂肪萎缩在糖尿病患者中并不罕见,2013年8期Diabetes Care刊登了Stricklan等的《2型糖尿病合并肢体部分性脂肪萎缩》一文,该文介绍了一种新的脂肪萎缩表型。来自NIH的Rother与Brown对该文进行了文献复习和评论。鉴于目前我国和全球T2DM患病者迅猛增加,而脂肪萎缩也是糖尿病合并症之一,为了引起临床医师对本合并症的重视,避免误漏诊,编辑部特将此二文介绍给本刊读者以供参考。 | 钱荣立 Strickland LR Guo F Lok K | 2015 | 中国糖尿病杂志2015，23，3： | 5 |
| 3 | Regulation of macrophage activation in the liver after acute injury: Role of the fibrinolytic system显示文摘The liver functions,in part,to prevent exposure of the body to potentially harmful substances ingested in the diet.While it is highly efficient at accomplishing this,it is frequently prone to liver injury due to the biotransformation of xenobiotics into toxic metabolites.To counter this injury,the liver has evolved a unique capacity to rapidly and efficiently repair itself.Successful resolution of acute liver injury relies on hepatic macrophage populations that orchestrate the reparative response.After injury,Kupffer cells,the resident macrophages of the liver,become activated and secrete proinflammatory cytokines.These cytokines recruit other immune cells,including monocyte-derived macrophages,to the liver where they contribute to the repair process.Monocyte-derived macrophages traffic into the necrotic foci where they rapidly phagocytose dead cell debris.Simultaneous with this process,these cells change phenotype from a proinflammatory macrophage to a prorestorative macrophage that produce pro-mitogenic growth factors and antiinflammatory cytokines.Ultimately this process triggers resolution of inflammation,and along with proliferation of other hepatic cells,restores the liver architecture and function.While the mechanisms regulating specific macrophage functions during repair remain to be elucidated,recent studies indicate a key role for the fibrinolytic system in coordinating macrophage function during repair.In this review,we will highlight the function and role of hepatic macrophages in repair after acute liver injury,and will discuss the role of the fibrinolytic enzyme,plasmin,in regulation of these various processes. | Katherine Roth Jenna Strickland Bryan L Copple | 2020 | World Journal of Gastroenterology2020，26，16： | 3 |
| 4 | Evaluation of serum biomarkers of fibrosis and injury in Egyptian patients with chronic hepatitis C显示文摘 | Gamal Esmat Mohamed Metwally Khalid R. Zalata Shahinaz Gadalla Mohamed Abdel-Hamid Amr Abouzied Abdel-Aziz Shaheen Maissa El-Raziky Hani Khatab Sherif El-Kafrawy Nabiel Mikhail Laurence S. Magder Nezam H. Afdhal G. Thomas Strickland | 2007 | Journal of Hepatology2007，，4： | 2 |
| 5 | 紫铜等离子体特征谱线及其展宽形成机制显示文摘利用波长为1064nm,最大能量为500mJ的Nd:YAG脉冲激光器对紫铜进行冲击,并且改变激光能量,获得一系列等离子体特征谱线,结果表明:本实验条件下,获得铜原子谱线不完整,只有5条明显激发谱线,分别为:CuⅠ406.33nm,CuⅠ458.69nm,CuⅠ521.8nm,CuⅠ529.25nm,CuⅠ578.2nm。根据跃迁原理,得出激光不能使铜原子完全受到激发;选取CuⅠ521.8nm原子光谱与CuⅠ578.2nm的原子光谱谱线线型作为分析对象,发现其展宽线型不同,分别为Lorenz线型与Gauss线型。通过对应线型曲线方程分析得出,同一原子光谱不同波段对应形成光谱展宽机制不同。 | 姚红兵 邢博 Donna Strickland 周祝生 丁桂林 佟艳群 平洁 李良湾 张永康 | 2012 | 强激光与粒子束2012，24，9： | 2 |
| 6 | A photoactive isoprenoid diphosphate analogue containing a stable phosphonate linkage: synthesis and biochemical studies with prenyhransferases 显示文摘 | DEGRAW A J ZHAO Z STRICKLAND C L | 2007 | J Org Chem2007，72，13： | 1 |
| 7 | Wavelet Transform Methods for Object Detection and Recovery显示文摘 | Robin N Strickland Hee Hahn | 1995 | IEEE Transactions on Image Processing1995，5，： | 1 |
| 8 | Induction of Differentiation in Teratocarcinoma Stem- cells by Retinoic Acid显示文摘 | Strickland S Mahdavi V | 1978 | Cell1978，15，2： | 1 |
| 9 | Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin显示文摘 | Chen ZL Strickland S | 1997 | Cell1997，91，： | 1 |
| 10 | 25th Anniversary presentation development of flexor tendonsurgery:Twenty-five years of progress显示文摘 | Strickland JW | 2000 | Hand Surg2000，25，2： | 1 |
| 11 | Tissue plasminogen activator(tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice显示文摘 | Wang YE Tsirka SE Strickland S | 1998 | Nat Med1998，4，： | 1 |
| 12 | Hormonal Induction of Differentiation in Teratocarcinoma Stem - cells - generation of Parietal Endoderm by Retinoic Acid and Dibutyryl Camp 显示文摘 | Strickland S Smith K K Marotti K R | 1980 | Cell1980，21，2： | 1 |
| 13 | Dystrophin expression in the mdx mouse restored by stem cell transplantation显示文摘 | Gussoni E Soneoka Y Strickland CD | 1999 | Nature1999，401，6751： | 1 |
| 14 | Gastrointestinal stromal tumors显示文摘 | Strickland L Letson GD Murocacho CA | 2001 | Cancer Control2001，8，： | 1 |
| 15 | Creating a positive business climate for women:An approach to small business development显示文摘 | BURR S G Strickland M | 1992 | Economic Development Review1992，10，1： | 1 |
| 16 | MicroRNA dysregu- lation following spinal cord contusion: implications for neural plas- ticity and repair 显示文摘 | Strickland ER Hook MA Balaraman S | 2011 | Neuroseience2011，186，： | 1 |
| 17 | Generation of ultrahigh peak power pulses by chirped pulse amplification显示文摘 | Maine P Strickland D Bado P | 1988 | IEEE J of Quantum Electronics1988，24，2： | 1 |
| 18 | Increased glucocorticoid receptor Beta expression converts mouse hybridoma cells to a corticosteroid-insensitive phenotype显示文摘 | Hauk PJ Goleva E Strickland I Vottero A | 2002 | Am J Respir Cell Mol Biol2002，27，3： | 1 |
| 19 | Pharmacist-physician collaboration in pain management practice 显示文摘 | STRICKLAND J M HUSKEY A BRUSHWOOD D B | 2007 | J Opioid Manag2007，3，6： | 1 |
| 20 | Virus infection and al lergy in the development of asthma what is the connec tion? 显示文摘 | Holt PG Strickland DH Sly PD | 2012 | Curr Opin Allergy Clin Immunol2012，12，2： | 1 |
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