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| 1 | Hazard and vulnerability evaluation of water distribution system in cases of contamination intrusion accidents显示文摘在这份报纸,它为危险和水分发网络的危险评估建议了一个索引系统,基于在不同连接的污染物质注射引起的污染事件的模拟。它试图在污染事件的情况中回答下列二个问题:1 ) 最危险的连接是哪个?2 ) 最脆弱的连接是哪个?与 EPANET 工具箱,它模仿了沾染物的繁殖,并且计算了在不同节点交付的沾染物和团的山峰集中。根据消费者的类型,不同重量为在消费者上估计沾染物的影响被分到消费者节点。用此处建议的方法,危险索引和危险索引在管子网络为每个节点被计算。介绍方法因此被用于 Zhenjiang 的城市的水网络,它包含二水植物,有存储坦克的二个增强软件抽水站。在结论,反应时间,在沾染物和全部的吸收的山峰集中之间的关系是在危险和水分发网络的危险评估的最重要的因素。 | Kunlun XIN Tao TAO Yong WANG Suiqing LIU | 2012 | Frontiers of Environmental Science & Engineering2012，6，6： | 2 |
| 2 | Suppression of vascular cell adhesion molecule - 1 expressi on by crocetin contributes to attenuation of atherosclerosis in hypercholesterolemic rabbits显示文摘 | Zheng Suiqing Qian Zhiyu Tang Futian | 2005 | Biochem Pharmacol2005，70，： | 1 |
| 3 | Overexpression of phosphorylated - STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma 显示文摘 | Suiqing C Min Z Lirong C | 2005 | J Dermatol2005，32，5： | 1 |
| 4 | Pro-inflammatory cytokine network in peripheral inflammation response to cerebral ischemia显示文摘 | Lili Zeng Yongting Wang Jianrong Liu Ling Wang Suiqing Weng Kewei Chen Edward F. Domino Guo-Yuan Yang | 2013 | Neuroscience Letters2013，，： | 1 |
| 5 | Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma 显示文摘 | SUIQING C MIN Z LIRONG C | 2005 | J Dermatol2005，32，： | 1 |
| 6 | Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma显示文摘 | Suiqing C Min Z Lirong C | 2005 | J Dermatol2005，32，5： | 1 |
| 7 | Cocktail Blood Biomarkers: Prediction of Clinical Outcomes in Patients with Acute Ischemic Stroke显示文摘 | Zeng Lili Liu Jianrong Wang Yongting Wang Ling Weng Suiqing Chen Shengdi Yang Guo-yuan | 2013 | European Neurology2013，，2： | 1 |
| 8 | Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma显示文摘 | Suiqing C Min Z Lirong C | 2005 | J Dermatol2005，32，5： | 1 |
| 9 | Overexpression of phosphorylated-STAT3 correlated with the invasion and metastasis of cutaneous squamous cell carcinoma显示文摘 | Suiqing C /tlin Z Lirong C | 2005 | J Dermatol2005，32，5： | 1 |
| 10 | Pro-inflammatory cytokine network in peripheral inflammation response to cerebral ischemia显示文摘 | Lili Zeng Yongting Wang Jianrong Liu Ling Wang Suiqing Weng Kewei Chen Edward F. Domino Guo-Yuan Yang | 2013 | Neuroscience Letters2013，，： | 1 |
| 11 | Cocktail Blood Biomarkers: Prediction of Clinical Outcomes in Patients with Acute Ischemic Stroke显示文摘 | Zeng Lili Liu Jianrong Wang Yongting Wang Ling Weng Suiqing Chen Shengdi Yang Guo-yuan | 2013 | European Neurology2013，，2： | 1 |
| 12 | Identification of (-)-bornyl diphosphate synthase from Blumea balsamifera and its application for (-)-borneol biosynthesis in Saccharomyces cerevisiae显示文摘Borneol is a precious monoterpenoid with two chiral structures,(-)-borneol and(+)-borneol.Bornyl diphosphate synthase is the key enzyme in the borneol biosynthesis pathway.Many(+)-bornyl diphosphate synthases have been reported,but no(-)-bornyl diphosphate synthases have been identified.Blumea balsamifera leaves are rich in borneol,almost all of which is(-)-borneol.In this study,we identified a high-efficiency(-)-bornyl diphosphate synthase(BbTPS3)from B.balsamifera that converts geranyl diphosphate(GPP)to(-)-bornyl diphosphate,which is then converted to(-)-borneol after dephosphorylation in vitro.BbTPS3 exhibited a K m value of 4.93±1.38μM for GPP,and the corresponding k cat value was 1.49 s−1.Multiple strategies were applied to obtain a high-yielding(-)-borneol producing yeast strain.A codon-optimized BbTPS3 protein was introduced into the GPP high-yield strain MD,and the resulting MD-B1 strain produced 1.24 mg⋅L^(-1)(-)-borneol.After truncating the N-terminus of BbTPS3 and adding a Kozak sequence,the(-)-borneol yield was further improved by 4-fold to 4.87 mg⋅L^(-1).Moreover,the(-)-borneol yield was improved by expressing the fusion protein module of ERG20 F96W-N127W-YRSQI-t14-BbTPS3K2,resulting in a final yield of 12.68 mg⋅L^(-1) in shake flasks and 148.59 mg⋅L^(-1) in a 5-L bioreactor.This work is the first reported attempt to produce(-)-borneol by microbial fermentation. | Rui Ma Ping Su Qing Ma Juan Guo Suiqing Chen Baolong Jin Haiyan Zhang Jinfu Tang Tao Zhou Chenghong Xiao Guanghong Cui Luqi Huang | 2022 | Synthetic and Systems Biotechnology2022，7，1： | 0 |
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