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| 1 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010,30,8: | 25 |
| 2 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005,26,8: | 6 |
| 3 | Rho/Rock signal transduction pathway is required for MSC tenogenic differentiation显示文摘Mesenchymal stem cell(MSC)-based treatments have shown promise for improving tendon healing and repair.MSCs have the potential to differentiate into multiple lineages in response to select chemical and physical stimuli, including into tenocytes. Cell elongation and cytoskeletal tension have been shown to be instrumental to the process of MSC differentiation. Previous studies have shown that inhibition of stress fiber formation leads MSCs to default toward an adipogenic lineage, which suggests that stress fibers are required for MSCs to sense the environmental factors that can induce differentiation into tenocytes. As the Rho/ROCK signal transduction pathway plays a critical role in both stress fiber formation and in cell sensation, we examined whether the activation of this pathway was required when inducing MSC tendon differentiation using rope-like silk scaffolds. To accomplish this, we employed a loss-of-function approach by knocking out ROCK,actin and myosin(two other components of the pathway) using the specific inhibitors Y-27632, Latrunculin A and blebbistatin, respectively. We demonstrated that independently disrupting the cytoskeleton and the Rho/ROCK pathway abolished the expression of tendon differentiation markers and led to a loss of spindle morphology. Together, these studies suggest that the tension that is generated by MSC elongation is essential for MSC teno-differentiation and that the Rho/ROCK pathway is a critical mediator of tendon differentiation on rope-like silk scaffolds. | Edward Maharam Miguel Yaport Nathaniel L Villanueva Takintope Akinyibi Damien Laudier Zhiyong He Daniel J Leong Hui B Sun | 2015 | Bone Research2015,3,3: | 4 |
| 4 | Effects of cold preservation and warm reperfusion on rat fatty liver显示文摘INTRODUCTIONAlthough liver transplantation for irreversible liverdiseases is increasingly prevalent worldwide,patientdie while waiting for donors because of organshortages.One important problem commonlyencountered is that fatty livers often affect theoutcome of liver transplantation.It is reported thatthe incidence of abnormal fatty livers in autopsiesafter accidental death ranged from 15% to 24%.Since fatty livers may result in a primarynonfunction (PNF)liver graft,which contributes | Sun B Jiang HC Piao DX Qiao HQ Zhang L | 2000 | World Journal of Gastroenterology2000,6,2: | 3 |
| 5 | Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics显示文摘 | Fang B Zheng C Liao L Han Q Sun Z Jiang X Zhao RC | 2006 | 中国生物学文摘2006,20,5: | 3 |
| 6 | 纳米光子结构软膜紫外光固化纳米压印(英文)显示文摘紫外光固化纳米压印是实现纳米结构批量复制的一种新技术.其特点是低成本和高分辨,而且可以达到极高的套刻精度.为了得到大面积图案的均匀复制,可用聚二甲基硅氧烷(PDMS)制备透光的压印软模板.其母版图案可由高分辨率电子束曝光和反应离子刻蚀的方法在硅片基底上获得,然后用浇注的方法将图案转移到PDMS上.本实验特别发展了紫外光固化纳米压印适用于软膜压印的双层膜图型转移技术.该双层膜由廉价的光胶和聚甲基丙烯酸甲脂(PMMA)构成.对光胶层的压印可用普通的光学曝光仪实现.然后再将图案用反应离子刻蚀的方法转移到PMMA层中.为了证明方案的可行性,在两种不同材料的半导体基片上压印了三角晶格的光子晶体和准晶结构的图案,并用剥离的方法将它们转移到金属薄膜上,最后成功地进行了硅片刻蚀实验.相信这一纳米制做方法对大面积纳米光子结构和光学集成芯片的制造是普遍适用的. | SHI J WANG Z M BAO K PEROZ C BELOTTI M XU L P LUO C X SUN M H ZHANG B JI H OUYANG Q CHEN Y | 2006 | 纳米技术与精密工程2006,4,3: | 2 |
| 7 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013,,1: | 2 |
| 8 | Lmmunohistochemical and insim hybridization studies of GnRH and its receptor显示文摘 | HUANG W Q YAO B SUN L | 2001 | Life Science2001,68,15: | 1 |
| 9 | Rare earth elements modification of laser-clad nickel-based alloy coatings 显示文摘 | K L Wang Q B Zhang M L Sun | 2001 | Applied Surface Science2001,174,34: | 1 |
| 10 | Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis显示文摘 | Hao X Sun B Hu L | 2004 | Cancer2004,100,6: | 1 |
| 11 | Wind-blown origin of the Pliocene red clay formation in the central Loess Plateau 显示文摘 | Ding Z L Sun J M Liu T S Zhu R X Yang S L Guo B | 1998 | Earth and Planetary Science Letters1998,161,: | 1 |
| 12 | A Geochemical Method for Reconstruction of the Occupation History of Penguin Colony in the Maritime Antarctic显示文摘 | SUN L G ZHU R B YIN X B | 2004 | Polar Biology2004,27,: | 1 |
| 13 | AB5-type hydrogen storage alloy used as anodic materials in borohydride fuel cell显示文摘 | Wang L B Ma C N Sun Y M | 2005 | J Alloy Compd2005,391,: | 1 |
| 14 | The competence of maize shoot meristems for integrative transformation and inherited expression of transgenes显示文摘 | Zhong H Sun B L Warkentin D | 1996 | Plant Physiol1996,110,: | 1 |
| 15 | External quality assessment for entero- virus 71 and coxsackievirus A16 detection by reverse transcription- PCR using armored RNA as a virus surrogate显示文摘 | Song L Sun S Li B | 2011 | J Clin Microbiol2011,49,10: | 1 |
| 16 | Hepatitis B virus with a pro- posed genotype I was found in sichuan province,China显示文摘 | TONG W B HE J L SUN L | 2012 | J Med Viro12012,84,6: | 1 |
| 17 | Quantitative evaluation of precipitates in an A1-Zn-Mg-Cu alloy after isothermal aging 显示文摘 | DU Z W SUN Z M SHAO B L ZHOU T T CHEN C Q | 2006 | Materials Characterization2006,56,: | 1 |
| 18 | Characterization of polyphenol oxidase from litchi pericarp using ( - ) - epicatechin as substrate 显示文摘 | Liu L Can S Xie B Sun Z Li X Miao W | 2007 | Journal of Agriculture and Food Chemistry2007,55,17: | 1 |
| 19 | Effects of contrasting soil management regimes on total and labile soil organic carbon fractions in a loess soil in China显示文摘 | Yang X Y Ren W D Sun B H Zhang S L | 2012 | Geoderma2012,177,: | 1 |
| 20 | Speaker clustering and cluster purification methods for RT07 and RT09 evaluation meeting data 显示文摘 | NWE T L SUN H MA B | 2012 | IEEE Transactions on Audio Speech and Language Processing2012,20,2: | 1 |