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| 1 | dentification of TRA2B-DNAH5 fusion as a novel oncogenic driver in human lung squamous cell carcinoma显示文摘 | Fei Li Zhaoyuan Fang Jian Zhang Chen Li Hongyan Liu Jufeng Xia Hongwen Zhu Chenchen auo Zhen Qin Fuming Li Xiangkun Han Yuetong Wang Yan Feng Ye Wang Wenjing Zhang Zuoyun Wang Yujuan Jin Yihua Sun Wenyi Wei Rong Zeng Haiquan Chen Hongbin Ji | 2016 | Cell Research2016，26，10： | 9 |
| 2 | A multi-layered Ti3C2/Li2S composite as cathode material for advanced lithium-sulfur batteries显示文摘Lithium-sulfur(Li-S)batteries with lithium sulfide(Li2S)as cathode have attracted great attention recently,because of high specific capacity(1166 mA h g^-1)of Li2S and potential safety of using Li metal-free anode.Li2S cathode has lower volume expansion and higher thermal stability than the traditional sulfur cathode.However,the problems of'shuttle effect'and poor electrical conductivity of the cathode material still need to be overcome.In this work,multi-layered Ti3C2/Li2S(ML-Ti3C2/Li2S)composite has been prepared and applied as a cathode in advanced Li-S batteries.The unique multi-layer sheet structure of Ti3 C2 provides space for the storage of Li2S,and its good conductivity greatly enhances the usage ratio of Li2 S and improves the conductivity of the whole Li2S cathode.Compared with commonly used graphene,ML-Ti3C2 can trap polysulfides effectively by chemical adsorption and also activate the reaction of Li2S to polysulfides by forming Ti-S bond.As a result,during the cycling of the batteries with ML-Ti3C2/Li2S cathodes,the activation voltage barrier of the first cycle has decreased to 2.8 V,and the'shuttle effect'has been suppressed effectively.The cycling and rate performances of the ML-Ti3C2/Li2S cathodes have been significantly improved compared to that of graphene/Li2 S cathodes.They maintain a capacity of 450 mAh g^-1 at 0.2 C after 100 cycles,and deliver attractive rate performances of 750,630,540,470 and 360 mAh g^-1 at 0.1 C,0.2 C,0.5 C,1 C,and 2 C,respectively. | Xin Liang Jufeng Yun Kun Xu Hongfa Xiang Yong Wang Yi Sun Yan Yu | 2019 | Journal of Energy Chemistry2019，28，12： | 4 |
| 3 | Synthesis,characterization and antibacterial properties of dihydroxy quaternary ammonium salts with long chain alkyl bromides显示文摘 | Liu Wenshuai Wang Chunhua Sun Jufeng | 2015 | Chem Biol Drug Des2015，85，1： | 1 |
| 4 | PD-L1^(+)exosomes from bone marrow-derived cells of tumor-bearing mice inhibit antitumor immunity显示文摘Tumors escape immune attack by upregulating the surface expression of PD-L1,which interacts with PD-1 on T cells to activate immune inhibitory signaling.Anti-PD-1 treatments can effectively block this inhibitory signaling and activate antitumor immune responses.However,anti-PD-1 treatment also has a tumor suppressive effect in patients whose tumor cells do not express PD-L1.The underlying mechanisms are poorly defined.Here,we report that exosomes from bone marrow-derived cells(BMDCs)in tumor-bearing mice,but not in healthy mice,carry PD-L1.PD-L1 on these exosomes is biofunctional and can inhibit CD8^(+)T cell proliferation and activation in vitro and in vivo.The transfer of exogenous exosomes from BMDCs and the inhibition of the production of endogenous exosomes by BMDCs promote and suppress tumor growth,respectively.PD-L1^(+)exosomes from BMDCs can be found in tumor tissues.In addition,exosomes from BMDCs promote tumor metastasis in a PD-L1-dependent manner.Therefore,our results indicate that exosomes from BMDCs play important roles in tumor immunosuppression via PD-L1. | Yan Sun Jufeng Guo Lei Yu Tianxin Guo Jiaoli Wang Xian Wang Yinghu Chen | 2021 | Cellular & Molecular Immunology2021，18，10： | 1 |
| 5 | A Dimension-Splitting Variational Multiscale Element-Free Galerkin Method for Three-Dimensional Singularly Perturbed Convection-Diffusion Problems显示文摘By introducing the dimensional splitting(DS)method into the multiscale interpolating element-free Galerkin(VMIEFG)method,a dimension-splitting multiscale interpolating element-free Galerkin(DS-VMIEFG)method is proposed for three-dimensional(3D)singular perturbed convection-diffusion(SPCD)problems.In the DSVMIEFG method,the 3D problem is decomposed into a series of 2D problems by the DS method,and the discrete equations on the 2D splitting surface are obtained by the VMIEFG method.The improved interpolation-type moving least squares(IIMLS)method is used to construct shape functions in the weak form and to combine 2D discrete equations into a global system of discrete equations for the three-dimensional SPCD problems.The solved numerical example verifies the effectiveness of the method in this paper for the 3D SPCD problems.The numerical solution will gradually converge to the analytical solution with the increase in the number of nodes.For extremely small singular diffusion coefficients,the numerical solution will avoid numerical oscillation and has high computational stability. | Jufeng Wang Yong Wu Ying Xu Fengxin Sun | 2023 | Computer Modeling in Engineering & Sciences2023，，4： | 1 |
| 6 | Hydrocarbon accumulation characteristics in basement reservoirs and exploration targets of deep basement reservoirs in onshore China显示文摘Based on the global basement reservoir database and the dissection of basement reservoirs in China,the characteristics of hydrocarbon accumulation in basement reservoirs are analyzed,and the favorable conditions for hydrocarbon accumulation in deep basement reservoirs are investigated to highlight the exploration targets.The discovered basement reservoirs worldwide are mainly buried in the Archean and Precambrian granitic and metamorphic formations with depths less than 4500 m,and the relatively large reservoirs have been found in rift,back-arc and foreland basins in tectonic active zones of the Meso-Cenozoic plates.The hydrocarbon accumulation in basement reservoirs exhibits the characteristics in three aspects.First,the porous-fractured reservoirs with low porosity and ultra-low permeability are dominant,where extensive hydrocarbon accumulation occurred during the weathering denudation and later tectonic reworking of the basin basement.High resistance to compaction allows the physical properties of these highly heterogeneous reservoirs to be independent of the buried depth.Second,the hydrocarbons were sourced from the formations outside the basement.The source-reservoir assemblages are divided into contacted source rock-basement and separated source rock-basement patterns.Third,the abnormal high pressure in the source rock and the normal–low pressure in the basement reservoirs cause a large pressure difference between the source rock and the reservoirs,which is conducive to the pumping effect of hydrocarbons in the deep basement.The deep basement prospects are mainly evaluated by the factors such as tectonic activity of basement,source-reservoir combination,development of large deep faults(especially strike-slip faults),and regional seals.The Precambrian crystalline basements at the margin of the intracontinental rifts in cratonic basins,as well as the Paleozoic folded basements and the Meso-Cenozoic fault-block basements adjacent to the hydrocarbon generation depressions,have favorable conditions for hydrocarbon accumulation,and thus they are considered as the main targets for future exploration of deep basement reservoirs. | WANG Zecheng JIANG Qingchun WANG Jufeng LONG Guohui CHENG Honggang SHI Yizuo SUN Qisen JIANG Hua ABULIMITI Yiming CAO Zhenglin XU Yang LU Jiamin HUANG Linjun | 2024 | Petroleum Exploration and Development2024，51，1： | 0 |
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