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| 1 | Isolation and characterization of a novel lectin with antifungal and antiproliferative activities from Sophora alopecuroides seeds显示文摘Sophora alopecuroides lectin (柳安) ,从 Sophora alopecuroides 的种子的新奇 lectin,被离子交换层析在 diethylaminoethyl (DEAE ) 上净化 - 并且 carboxymethyl (厘米)-Sepharose 列,在 Sephadex 75 10/300 GL 列上由胶化过滤列在后面。柳安被发现是 39916.3 Da 的单体,由 tricine 钠 dodecyl sulphate-polyacrylamide 胶化电气泳动和高效的液体层析决定了 HPLC ) 。柳安的 N 终端 10-amino 酸顺序, KPWALSFSFG,另外的荚 lectins 类似于那些。对在 11.9 g/ml 的兔子红血球的柳安展览 hemagglutinating 活动。它的 hemagglutinating 活动在 pH 范围是稳定的 711 并且在温度范围 3090 吗? | Tingting Li Xiaoli Yin Dongliang Liu Xiaojin Ma Hui Lv Surong Sun | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 2 | Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China显示文摘The Crimean-Congo hemorrhagic fever virus(CCHFV),a member of the genus Orthonairovirus and family Nairoviridae,is transmitted by ticks and causes severe hemorrhagic disease in humans.To study the epidemiology of CCHFV in different ecosystems in Xinjiang,China,a total of 58,932 ticks were collected from Tarim Basin,Junggar Basin,Tianshan Mountain,and Altai Mountain from 2014 to 2017.Hyalomma asiaticum asiaticum was the dominant tick species in Tarim and Junggar basins,whereas Dermacentor nuttalli and Hyalomma detritum were found in Tianshan Mountain and Altai Mountain,respectively.Reverse transcription-polymerase chain reaction of the CCHFV small(S)genome segment was used for the molecular detection.The CCHFV-positive percentage was 5.26%,6.85%,1.94%,and 5.56% in Tarim Basin,Junggar Basin,Tianshan Mountain,and Altai Mountain,respectively.Sequences of the S segment were used for phylogenetic analysis and the results showed that the newly identified CCHFV strains belonged to two clades.Our study confirms that H.asiaticum asiaticum is the major vector of CCHFV in desert habitats which is consistent with previous studies,and also suggests that H.detritum and D.nuttalli are emerging vectors for CCHFV in Xinjiang.Moreover,this study reports the presence of CCHFV in the mountain habitat of Xinjiang for the first time,suggesting that future surveillance of CCHFV should also include mountainous areas. | Abulimiti Moming Xihong Yue Shu Shen Chenchen Chang Cheng Wang Tao Luo Yanfang Zhang Rong Guo Zhihong Hu Yujiang Zhang Fei Deng Surong Sun | 2018 | Virologica Sinica2018，33，1： | 5 |
| 3 | Structural changes in pyramidal cell dendrites and synapses in the unaffected side of the sensorimotor cortex following transcranial magnetic stimulation and rehabilitation training in a rat model of focal cerebral infarct显示文摘Very little is known about the effects of transcranial magnetic stimulation and rehabilitation training on pyramidal cell dendrites and synapses of the contralateral,unaffected sensorimotor cortex in a rat model of focal cerebral infarct.The present study was designed to explore the mechanisms underlying improved motor function via transcranial magnetic stimulation and rehabilitation training following cerebral infarction.Results showed that rehabilitation training or transcranial magnetic stimulation alone reduced neurological impairment in rats following cerebral infarction,as well as significantly increased synaptic curvatures and post-synaptic density in the non-injured cerebral hemisphere sensorimotor cortex and narrowed the synapse cleft width.In addition,the percentage of perforated synapses increased.The combination of transcranial magnetic stimulation and rehabilitation resulted in significantly increased total dendritic length,dendritic branching points,and dendritic density in layer V pyramidal cells of the non-injured cerebral hemisphere motor cortex.These results demonstrated that transcranial magnetic stimulation and rehabilitation training altered structural parameters of pyramidal cell dendrites and synapses in the non-injured cerebral hemisphere sensorimotor cortex,thereby improving the ability to compensate for neurological functions in rats following cerebral infarction. | Chuanyu Liu Surong Zhou Xuwen Sun Zhuli Liu Hongliang Wu Yuanwu Mei | 2011 | Neural Regeneration Research2011，6，9： | 2 |
| 4 | Purification and characterization of a novel antifungal protein with antiproliferation and anti-HIV-1 reverse transcriptase activities from Peganum harmala seeds显示文摘新奇抗真菌的蛋白质,指定了为 PHP,从 Peganum harmala 的种子被孤立,由资源 S 列上的 cationic 交换层析和 Sephadex 75 10/300 GL 上的胶化过滤列。PHP 被发现形成大约 16 kDa 的 homodimer。等电位的集中 polyacrylamide 胶化电气泳动分析证明 PHP 的等电位的点是 8.4。PHP 的 N 终端 20-amino 酸顺序, ITCPQVTQSLAPCVPYLISG,在某些植物类似于非特定的类脂化合物转移蛋白质。PHP 展出了类脂化合物绑定活动。而且, PHP 对 Alternaria 替换物,毛丛 degitatum, Rhizopus stuolonifer,和 Magnaporthe grisea 施加了抗真菌的活动,并且它的抗真菌的活动在温度范围是稳定的 460 瑮晩湵慧 ? 牰瑯楥? 楷桴愠瑮灩潲楬敦慲楴湯愠摮愠瑮 ???? 敲敶獲? 牴湡 ' 諛 L 瑰獡 ? 捡楴楶楴獥映潲 ? 敐慧畮 ? 慨浲污 ?敳摥 s 瑮吗?? | Xiaojin Ma Dongliang Liu Haishu Tang Yan Wang Ting Wu Yang Li Jie Yang Jianhua Yang Surong Sun Fuchun Zhang | 2013 | Acta Biochimica et Biophysica Sinica2013，45，2： | 1 |
| 5 | A CONTROLLED STUDY OF THERAPEUTIC EFFECTS OF COMPUTER-CONTROLLED ELECTRIC ACUPUNCTURE TREATMENT ON REFRACTORY SCHIZOPHRENIA显示文摘Out of 100 cases of intractable schizophrenia,57 cases were in the group ofComputer-Controlled Electric Acupuncture (CCEA) and 43 in the control group.The therapeutic re-sults showed that clinically CCEA had a remarkably effective rate of 40. 35% on refractoryschizophrenia,which had much better curative effects than those in the control group.Through dy-namic evaluation of brief psychiatric rating scale (BPRS),negative symptom scale (SANS) and posi-tive symptom scale (SAPS) for both groups before,during and after treatment,the results indicatedthat in CCEA group the scores of BPRS,SANS and SAPS after treatment were much less than thosebefore treatment,which were remarkably different from those in the control group (P<0.01).Lab-oratory examination of thyroxin and androgen of patients in both groups before and after treatmentfound a significant result. | Zhang Ben Meng Surong Yu Jiang Quan Changgeng Li Wentong Sun Hexiang Zhang Baoting Shi Qiuying Kailuan Psychiatric Hospital,Tangshan 063001,ChinaWang Jianjun Kailuan Hospital,Tangshan 063001,China | 1993 | World Journal of Acupuncture-Moxibustion1993，3，4： | 1 |
| 6 | Molecular cloning, expression, and characterization of a Sophora alopecuroides lectin from Escherichia coli显示文摘Sophora alopecuroides lectin (柳安) 从种子被孤立并且证实了有抗真菌并且 antitumor 活动,并且一会儿自然 lectin 的准备是拖累的,费时间,并且收益为进一步的分析是相对低的。在这研究, lectin,修正地点,和第二等的结构的信号肽被分析,并且柳安的三维的结构被建模。柳安的基因被反向的抄写聚合酶链反应放大,并且克隆进 pET-30a 向量并且由 isopropyl-beta-d-thiogalactopyranoside 的正式就职在 Escherichia coli BL21 (DE3 ) 表示了。完全, recombinant 柳安(rSAL ) 的 400 mg 通过 Ni-NTA agarose 列从细菌的文化的 1 l 被净化,纯净到达了 95% 。recombinant 蛋白质被西方的污点进一步用 rSAL 特定的抗体证实。生物活动分析结果显示出只绑在 d 半乳糖并且举办了通用 hemagglutinating 活动到人的 A, B, O,和 AB 的那 rSAL,并且兔子和老鼠红血球。rSAL 也禁止了真菌,癌症细胞的增长,和 HIV-I 反向的 transcriptase 活动的生长。在结论,这研究显示 rSAL 能在原核生物的表示系统在大数量被生产, recombinant 蛋白质仍然保留各种各样的生物活动,它将以可能的戏剧性地减少的成本做柳安 recombinant 蛋白质的大规模生产。 | Yang Li Tingting Li Jinyao Li Dongliang Liu Jie Yang Jianhua Yang Fuchun Zhang Surong Sun | 2014 | Acta Biochimica et Biophysica Sinica2014，46，9： | 0 |
| 7 | Types of biogenic quartz and its coupling storage mechanism in organic-rich shales: A case study of the Upper Ordovician Wufeng Formation to Lower Silurian Longmaxi Formation in the Sichuan Basin, SW China显示文摘Biogenic quartz in the Upper Ordovician Wufeng Formation to Lower Silurian Longmaxi Formation(WufengLongmaxi)shale layers in the Sichuan Basin and its periphery is qualitatively analyzed and quantitatively characterized by organic petrologic,mineralogic,and geochemical methods to find out the coupling effect between organic matter and quartz.(1)There are two types of biogenic quartz in the shale layers:Type I quartz is submicron quartz appearing in clusters around the organic matter.Type II quartz is in nano-scale grain size and floats in spherical shape on organic matter,with grains in point-to-point or surface-to-surface contact;this type of quartz is mainly biologic origin and slightly affected by hydrothermal activity in local parts.(2)The reservoirs in the Wufeng-Longmaxi formations is consistent in distribution with biogenic silica content in them,and mainly concentrated at the bottom of the Wufeng-Longmaxi formations,and is thinner in the Changning and Weiyuan regions,while thicker in the Fuling region.(3)The biogenic quartz in the Wufeng-Longmaxi shale worked through the entire evolution process of hydrocarbon generation.The presence of biogenic quartz can enhance the development of organic matter pores and microcracks,and can effectively preserve the organic matter pores and residual intergranular pores,forming'biological silicon intergranular pores,organic pores and micro-fractures'.This would benefit later hydraulic fracturing and result in high production/stable production of well.The coupling effect between biogenic quartz development and organic matter evolution and hydrocarbon generation is a critical factor for high-quality shale reservoir development. | GUAN Quanzhong DONG Dazhong ZHANG Hualing SUN Shasha ZHANG Surong GUO Wen | 2021 | Petroleum Exploration and Development2021，48，4： | 0 |
| 8 | Antigenicity of severe fever with thrombocytopenia syndrome virus nucleocapsid protein and its potential application in the virus serodiagnosis显示文摘Dear Editor,Severe fever with thrombocytopenia syndrome virus(SFTSV)is a newly identified viral pathogen of the genus Phlebovirus in the family Bunyaviridae(Sun et al.,2012).SFTSV was first identified from patient serum samples in China(Li et al.,2013;Ning et al.,2015).SFTSV can cause a severe hemorrhagic fever-like disease with a reported case fatality rate ranging from 2.5% | Abulimiti Moming Yujiang Zhang Chenchen Chang Huan Yu Meifang Wang Zhihong Hu Fei Deng Surong Sun | 2017 | Virologica Sinica2017，32，1： | 0 |
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