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| 1 | Cloning of differentially expressed genes in human hepatocellular carcinoma and nontumor liver显示文摘INTRODUCTIONThe mechanism of hepatocellular carcinoma(HCC)is still unclear,although some genes have been found to play a role in the transformation of liver cells,and a variety of studies have described differences in gene expression which distinguished tumor from nontumor[1-6].The new genes,especially the functional genes directly related with tumor are still worth being found.The purpose of our study is to find the different genes between human liver tumor and normal tissues using suppression subtractive hybridization. | Xiao-Yan Cao Jie Liu Zhao-Rui Lian Marcy Clayton Jia-Lu Hu Ming-Hua Zh Dai-Ming Fan Mark Feitelson Institute of Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,ChinaDepartment of Pathology & Cell Biology,Thomas Jefferson University,Philadelphia,PA19107 USADepartment of Pathology,Second Military Medical University,Shanghai 200433,China | 2001 | World Journal of Gastroenterology2001，7，4： | 7 |
| 2 | Early surgery in Crohn's disease a benefit in selected cases显示文摘AIM: To compare the outcomes of a cohort of Crohn's disease(CD) patients undergoing early surgery(ES) to those undergoing initial medical therapy(IMT).METHODS: We performed a review of a prospective database CD patients managed at a single tertiary institution. Inclusion criteria were all patients with ileal or ileocolonic CD between 1995-2014. Patients with incomplete data, isolated colonic or perianal CD were excluded. Primary endpoints included the need for, and time to subsequent surgery. Secondary endpoints included the number and duration of hospital admissions, and medical therapy. RESULTS: Forty-two patients underwent ES and 115 underwent IMT. The operative intervention rate at 5 years in the ES group was 14.2% vs IMT 31.3%(HR = 0.41, 95%CI: 0.23-0.72, P = 0.041). The ES group had fewer hospital admissions per patient [median 1 vs 3(P = 0.012)] and fewer patients required anti-TNF therapy than IMT(33.3% vs 57%, P = 0.003). A subgroup analysis of 62 IMT patients who had undergone surgery were compared to ES patients, and showed similar 5 year(from index surgery) re-operation rates 16.1% vs 14.3%. In this subset, a significant difference was still found in median number of hospital admissions favouring ES, 1 vs 2(P = 0.002).CONCLUSION: Our data supports other recent studies suggesting that patients with ileocolonic CD may have a more benign disease course if undergoing early surgical intervention, with fewer admissions to hospital and atrend to reduced overall operation rates. | Vinna An Lauren Cohen Matthew Lawrence Michelle Thomas Jane Andrews James Moore | 2016 | World Journal of Gastrointestinal Surgery2016，8，7： | 3 |
| 3 | Measurement of muscle activity with magnetic resonance elastography显示文摘 | Guido Heers Thomas Jenkyn M. Alex Dresner Marc-Oliver Klein Jeffrey R Basford Kenton R Kaufman Richard L Ehman Kai-Nan An | 2003 | Clinical Biomechanics2003，，6： | 2 |
| 4 | Noninvasive muscle tension measurement using the novel technique of magnetic resonance elastography (MRE)显示文摘 | Thomas R. Jenkyn Richard L. Ehman Kai-Nan An | 2003 | Journal of Biomechanics2003，，12： | 2 |
| 5 | Effect of a near-zero magnetic field on development and flight of oriental armyworm(Mythimna separata)显示文摘The geomagnetic field affects all living organisms on the Earth.In this study we investigated the developmental and behavioral effects of rearing Mythimna separata in a near-zero magnetic field(<500 n T)compared to the local geomagnetic field(approximately 50μT).The near-zero magnetic field produced by a Helmholtz coil system significantly lengthened larval and pupal development durations,increased male longevity,and reduced pupal weight,female reproduction,and the relative expression level of the vitellogenin(Vg)gene in newly emerged females.Moreover,the near-zero magnetic field had a considerable negative effect on the mating ratio of M.separata adults.In addition,the moths in the near-zero magnetic field displayed less flight activity late in the night than those in the Earth's normal geomagnetic field,indicating that the flight rhythm of M.separata may be affected by the near-zero magnetic field.Reduction in magnetic field intensity may have negative effects on the development and flight of oriental armyworm,with consequent additional effects on its migration. | AN Meng-meng ZHANG Lei CHENG Yun-xia Thomas W.SAPPINGTON PAN Wei-dong JIANG Xing-fu | 2021 | Journal of Integrative Agriculture2021，20，5： | 2 |
| 6 | Adaptive Wall-Based Attachment Ventilation:A Comparative Study on Its Effectiveness in Airborne Infection Isolation Rooms with Negative Pressure显示文摘The transmission of coronavirus disease 2019(COVID-19)has presented challenges for the control of the indoor environment of isolation wards.Scientific air distribution design and operation management are crucial to ensure the environmental safety of medical staff.This paper proposes the application of adaptive wall-based attachment ventilation and evaluates this air supply mode based on contaminants dispersion,removal efficiency,thermal comfort,and operating expense.Adaptive wall-based attachment ventilation provides a direct supply of fresh air to the occupied zone.In comparison with a ceiling air supply or upper sidewall air supply,adaptive wall-based attachment ventilation results in a 15%–47%lower average concentration of contaminants,for a continual release of contaminants at the same air changes per hour(ACH;10 h^(-1)).The contaminant removal efficiency of complete mixing ventilation cannot exceed 1.For adaptive wall-based attachment ventilation,the contaminant removal efficiency is an exponential function of the ACH.Compared with the ceiling air supply mode or upper sidewall air supply mode,adaptive wall-based attachment ventilation achieves a similar thermal comfort level(predicted mean vote(PMV)of0.1–0.4;draught rate of 2.5%–6.7%)and a similar performance in removing contaminants,but has a lower ACH and uses less energy. | Ying Zhang Ou Han Angui Li Li’an Hou Thomas Olofsson Linhua Zhang Wenjun Lei | 2022 | Engineering2022，8，1： | 2 |
| 7 | Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds. | Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，6： | 2 |
| 8 | Occult splenic rupture with cardiovascular collapse: a report of three cases in critically ill patients显示文摘 | Subramani K Thomas AN Reeve RS | 2002 | Intensive Care Med2002，28，12： | 1 |
| 9 | Transfusion requirements duringcontinuous veno-venous haemofiltration:the importance of filterLife显示文摘 | Cutts MW Thomas AN Kishen R | 2000 | Intensive Care Med2000，26，11： | 1 |
| 10 | Nitrogen fixationand leaching of biological soil crust communities in mesictemperate soils显示文摘 | Roberta MV Deborah AN Thomas RW | 2006 | Microbial Ecology2006，51，2： | 1 |
| 11 | Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease显示文摘 | THORBUM AN O'SULLIVAN BJ THOMAS R | 2010 | Thorax2010，65，12： | 1 |
| 12 | Modeling neurodegenerative disorders in adult somatic cells: A critical review显示文摘为 neurodegenerative 混乱的新治疗学的目标的开发被信赖在结束阶段疾病是代表性的帖子 mortem 织物上,或在没能提供忠诚类似物的动物模型上妨碍了。然而,在细胞的基因 reprogramming 的快速的进展,特别地进干细胞的体的房间的正式就职,或直接进神经原,在在 vitro 人的 neurodegeneration 当模特儿导致了强烈兴趣。这里,我们极其在 Alzheimers 疾病, Parkinsons 疾病和 amyotrophic 的细胞的模型考察当前的方法和最近的进步侧面的硬化。几挑战被识别,包括为分散的疾病的模型的技术可变性,退化显型的缺乏, neurodevelopmental 年龄和建立的地面真相。为评估 neurodegenerative 的建议细胞的模型为未来研究与建议一起被建议。 | An Truong Emily Si Thomas Duncan Michael Valenzuela | 2016 | Frontiers in Biology2016，11，3： | 1 |
| 13 | Assay systems and characterization of Pacific whiting protease 显示文摘 | An Haejung S Thomas A W Junwen | 1994 | Journal of Food Science1994，59，2： | 1 |
| 14 | Use of a patient information system to audit the introduction of modified early warning scoring 显示文摘 | Quarterman CP Thomas AN McKenna M | 2005 | J Eval Clin Pratt2005，11，2： | 1 |
| 15 | Transfusion requirements during continuous veno-venous haemofihration : the importance of filter life 显示文摘 | Cutts MW Thomas AN Kishen R | 2000 | Intensive Care Med2000，26，11： | 1 |
| 16 | Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging显示文摘 | Binh An P. Phan Baocheng Chu Nayak Polissar Thomas S. Hatsukami Chun Yuan Xue-Qiao Zhao | 2007 | The International Journal of Cardiovascular Imaging2007，，3： | 1 |
| 17 | Patient safety incidents associated with airway devices in critical care:a review of reports to the UK National Patient Safety Agency显示文摘 | Thomas AN Mc Grath BA | 2009 | Anaesthesia2009，64，4： | 1 |
| 18 | Noninrasive measurement of cardiac output during induction of anesthesia and tracheal intubation: thiopentone and propofol显示文摘 | Vohra A Thomas AN Harper HJN | 1991 | Br J Anaesth1991，67，： | 1 |
| 19 | Use of a patient infor- mation system to audit the introduction of modified early warning scoring 显示文摘 | Quarterman CP Thomas AN Mckenna M el al | 2005 | J Eval Clin Pract2005，11，2： | 1 |
| 20 | Non-invasive measuryement of cardiac output during induction of anesthesia and tracheal intubation:thiopentone and propofol compared显示文摘 | Vohra A Thomas AN Harper NJ | 1991 | Br J Aneath1991，67，1： | 1 |
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