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| 1 | Insight-HXMT observations of the first binary neutron star merger GW170817显示文摘Finding the electromagnetic(EM) counterpart of binary compact star merger, especially the binary neutron star(BNS) merger,is critically important for gravitational wave(GW) astronomy, cosmology and fundamental physics. On Aug. 17, 2017,Advanced LIGO and Fermi/GBM independently triggered the first BNS merger, GW170817, and its high energy EM counterpart,GRB 170817 A, respectively, resulting in a global observation campaign covering gamma-ray, X-ray, UV, optical, IR, radio as well as neutrinos. The High Energy X-ray telescope(HE) onboard Insight-HXMT(Hard X-ray Modulation Telescope) is the unique high-energy gamma-ray telescope that monitored the entire GW localization area and especially the optical counterpart(SSS17 a/AT2017 gfo) with very large collection area(~1000 cm^2) and microsecond time resolution in 0.2-5 MeV. In addition,Insight-HXMT quickly implemented a Target of Opportunity(ToO) observation to scan the GW localization area for potential X-ray emission from the GW source. Although Insight-HXMT did not detect any significant high energy(0.2-5 MeV) radiation from GW170817, its observation helped to confirm the unexpected weak and soft nature of GRB 170817 A. Meanwhile,Insight-HXMT/HE provides one of the most stringent constraints(~10^(-7) to 10^(-6) erg/cm^2/s) for both GRB170817 A and any other possible precursor or extended emissions in 0.2-5 MeV, which help us to better understand the properties of EM radiation from this BNS merger. Therefore the observation of Insight-HXMT constitutes an important chapter in the full context of multi-wavelength and multi-messenger observation of this historical GW event. | TiPei Li ShaoLin Xiong ShuangNan Zhang FangJun Lu LiMing Song XueLei Cao Zhi Chang Gang Chen Li Chen TianXiang Chen Yong Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong YuanYuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao CongZhan Liu GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge OU JinLu Qu Na Sai Liang Sun Yin Tan Lian Tao WenHui Tao YouLi Tuo GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BoBing WU Mei Wu GuangCheng Xiao He Xu YuPeng Xu LinLi Yan JiaWei Yang Sheng Yang YanJi Yang AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang Shu Zhang Tong Zhang Wei Zhang WanChang Zhang WenZhao Zhang Yi Zhang Yue Zhang YiFei Zhang YongJie Zhang Zhao Zhang ZiLiang Zhang HaiSheng Zhao JianLing Zhao XiaoFan Zhao ShiJie Zheng Yue Zhu YuXuan Zhu ChangLin Zou | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，3： | 12 |
| 2 | Reuse of Fenton sludge as an iron source for NiFe_2O_4 synthesis and its application in the Fenton-based process显示文摘The potentially hazardous iron-containing sludge from the Fenton process requires proper treatment and disposal, which often results in high treatment cost. In this study, a novel method for the reuse of Fenton sludge as an iron source for the synthesis of nickel ferrite particles(NiFe_2O_4) is proposed. Through a co-precipitation method followed by sintering at 800°C, magnetic NiFe_2O_4 particles were successfully synthesized, which was confirmed by powder X-ray diffraction(XRD), scanning electronic microscopy(SEM), energy dispersive spectroscopy(EDS), Fourier transform infrared spectroscopy(FT-IR) and Raman spectroscopy. The synthesized NiFe_2O_4 could be used as an efficient catalyst in the heterogeneous Fenton process. In phenol degradation with H_2O_2 or NiFe_2O_4 alone, the phenol removal efficiencies within the reaction time of 330 min were as low as 5.9% ± 0.1% and 13.5% ±0.4%, respectively. However, in the presence of both NiFe_2O_4 and H_2O_2, phenol removal efficiency as high as 95% ± 3.4% could be achieved, indicating the excellent catalytic performance of NiFe_2O_4 in the heterogeneous Fenton process. Notably, a rapid electron exchange between_Ni II and_Fe III ions in the NiFe_2O_4 structure could be beneficial for the Fenton reaction. In addition, the magnetic catalyst was relatively stable, highly active and recoverable, and has potential applications in the Fenton process for organic pollutant removal. | Hui Zhang Jianguo Liu Changjin Ou Faheem Jinyou Shen Hongxia Yu Zhenhuan Jiao Weiqing Han Xiuyun Sun Jiansheng Li Lianjun Wang | 2017 | Journal of Environmental Sciences2017，29，3： | 10 |
| 3 | Stems and leaves of Aconitum carmichaelii Debx.as potential herbal resources for treating rheumatoid arthritis: Chemical analysis,toxicity and activity evaluation显示文摘According to folk usage of Aconitum carmichaelii Debx., the present study was designed to determine the feasibility of the stems and leaves of Aconitum carmichaelii Debx. as a new medicinal resource. Fourteen alkaloids in mother roots, fibrous roots, stems, and leaves of Aconitum carmichaelii Debx. were measured by HPLC-MS/MS. And multivariate analysis methods, such as clustering analysis and principal component analysis, were applied to analyze the difference among various parts. In addition, the acute toxicity, analgesia, and anti-inflammatory tests were carried out. The results suggested that the contents of alkaloids in mother roots and fibrous roots were approximate, but those of leaves and stems were different from mother roots and fibrous roots. The results of the acute toxicity testing demonstrated the toxicity of fibrous root was strongest, and mother roots were slightly less toxic than fibrous roots. The stems and leaves were far less toxic than mother and fibrous roots. In addition, the analgesia and inflammatory tests showed the effects of the various tissues had no difference each other. These results provided a basis for developing new complementary and alternative treatments for rheumatoid arthritis patients. Simultaneously, the approach may also turn wastes into treasure and promote the development of circular economy. | HE Ya-Nan OU Shui-Ping XIONG Xi PAN Yuan PEI Jin XU Run-Chun GENG Fu-Neng HAN Li ZHANG Ding-Kun YANG Ming | 2018 | Chinese Journal of Natural Medicines2018，16，9： | 10 |
| 4 | Malnutrition and Quality of Life in Chinese Cancer Patients: a Clinical Study of 23,994 Subjects显示文摘Background Malnutrition is common in patients with cancer,and can negatively impact their quality of life(QoL)and even survival.However,there is currently no large data available on the prevalence of malnutrition in Chinese cancer patients.This study evaluated the prevalence of malnutrition and the QoL of Chinese patients with locoregional,recurrent or metastatic cancer.Methods We conducted a nationwide observational,multi-center,hospital-based cross-sectional study within the Chinese Society of Nutritional Oncology(CSNO)Network.All of the patients were diagnosed with one of the following 18 different types of malignant tumors:lung cancer,gastric cancer,liver cancer,colorectal cancer,breast cancer,esophageal cancer,cervical cancer,endometrial cancer,nasopharyngeal carcinoma,malignant lymphoma,leukemia,pancreatic cancer,ovarian cancer,prostate cancer,bladder cancer,brain cancer,biliary tract malignant tumors or gastrointestinal stromal tumors.These patients were enrolled from 72 hospitals located in different regions of China.The patients’nutritional status was evaluated based on the body mass index(BMI),loss of bodyweight,laboratory measurements and patient generated-subjective global assessment(PG-SGA)scores.The cancer patients’physical status and QoL were assessed by the Karnofsky Performance Status(KPS)questionnaire and the European Organization for Research and Treatment of Cancer(EORTC)QLQ-C30 questionnaire,respectively.Results From December 2013 to April 2016,23,994 patients hospitalized for cancer treatment(such as surgery,chemotherapy or radiotherapy)were enrolled in the study.The patients included 12,494(52.9%)males and 11,124(47.1%)females.The mean age was 55.8±13.7 years.The proportions of patients in cancer stagesⅠ,Ⅱ,Ⅲ,Ⅳand uncertain were 11.5%,20.3%,27.5%,30.2%and 10.5%,respectively.Among the 23,994 inpatients,the proportions of patients who were underweight(BMI<18.5 kg/m2),normal(18.5 kg/m2 | Hong Xia Xu Chun Hua Song Zhen Ming Fu Chang Wang Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Jiu Wei Cui Wei Li Han Ping Shi the Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2021 | Journal of Nutritional Oncology2021，6，1： | 8 |
| 5 | Fossil Association from the Lower Cambrian Yanjiahe Formation in the Yangtze Gorges Area,Hubei,South China显示文摘摘要:除了以前报导的小壳的石块(SSF ) ,一个宏观的石块集合,包括的丰富的水藻,锥形的管状的石块形式,和可能的印象一放大了后生动物,在西方的湖北省的 Yangtze 峡区域来自更低的寒武纪的 Yanjiahe 形成,华南。可见石块在 thinlaminated siltstone 被保存或泥泞 siltstone 在 815 公里厚的碳酸盐存款之间设置了,浅水里的抑制本地消沉的可能代表的沉积背景在早寒武纪的 Meishucunian 阶段期间焦化站台。宏观的石块协会关于生活的进化提供重要石块证据从对寒武纪的爆炸间隔晚前寒武纪。 | GUO Junfeng LI Yong HAN Jian ZHANG Xingliang ZHANG Zhifei OU Qiang LIU Jianni SHU Degan Shigenori MARUYAMA Tsuyoshi KOMIYA | 2008 | Acta Geologica Sinica(English Edition)2008，82，6： | 8 |
| 6 | Effect of Fe, Si and Cooling Rate on the Formation of Fe-and Mn-rich Intermetallics in Al–5Mg–0.8Mn Alloy显示文摘The Fe-and Mn-rich intermetallics are of great effect on the mechanical properties of the AA5083 type alloy(Al–5Mg–0.8Mn). The effect of Fe, Si and cooling rate on the formation of the intermetallics were investigated by analyzing the microstructures of the alloys with different Fe and Si contents. The results indicated that increasing the Fe content resulted in the increase of the Al_6(Fe,Mn) phase in both amount and size. In the alloys with high Fe content, the platelet-like Al_6(Fe,Mn) compounds lined up and formed a band. Increasing the content of Si resulted in the increase of the Mg_2 Si phase which formed a network structure. Increasing the cooling rate significantly refined the intermetallics. However, increasing the cooling rate did not change the characteristic of the intermetallic compounds in the alloys with low or medium Si contents. For the alloys with high contents of Fe and Si under the condition of near-rapid cooling, the Fe- and Mn-rich intermetallic compound changed to the quaternary (Al)_15(Fe,Mn)_3Si phase and displayed a fine fish bone or Chinese script structure. The refinement of the intermetallics would allow higher tolerance of Fe and Si contents in the AA5083 alloy produced, for instance, via the continuous strip casting process. | Yulin Liu Lei Luo Chaofei Han Liangyun Ou Jijie Wang Chunzhong Liu | 2016 | Journal of Materials Science & Technology2016，32，4： | 7 |
| 7 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 8 | Validity of the Chinese Version of the Patient-Generated Subjective Global Assessment (PG-SGA) in Lung Cancer Patients显示文摘The prevalence of malnutrition is high among oncology patients in China. Although the Patient- Generated Subjective Global Assessment (PG-SGA) is widely recognized as an important nutritional assessment tool, it has not been validated for Chinese cancer patients. The purpose of this study was to conduct an analysis of nutrition screening and assessment data to validate the Chinese version of the PG-SGA in Chinese patients with lung cancer. This was an observational, cross-sectional study of 2,000 consecutive adult patients with lung cancer treated at several tertiary hospitals in China. Anthropometric and patient descriptive data were collected. The PG-SGA generated a score for the nutritional risk and a global rating for the nutritional status. The internal consistency, external consistency, and construct validity were evaluated, and a known-groups comparison and principal component analyses were conducted to evaluate the reliability and validity of the PG-SGA. The known-groups comparison demonstrated the ability of the PG-SGA to differentiate lung cancer patients of different nutritional and body mass index (BMI) groups. A confirmatory factor analysis supported the original four-factor structure of the PG-SGA. In terms of the internal and external consistency, the PG-SGA demonstrated intra-class correlation coefficients (ICC) up to 0.987. Alternative form validity was also demonstrated between Box 4 of the PG-SGA and the Karnofsky Performance Status score, with excellent external consistency (r = 0.972, P < 0.001). The construct validity was supported, and selected questionnaire dimensions were evident in the principal component analysis. Significant Spearman correlations (P < 0.001) were demonstrated. The Chinese version of the PG-SGA demonstrated significant reliability and sufficient exploratory properties to support its validity. It seems to be a valid tool that can be used to access the nutritional status of Chinese lung cancer patients. The validity of the PG-SGA in Chinese cancer patients warrants further investigation in other cancer types. | Zhen Ming Fu Hong Xia Xu Chun Hua Song Wei Li Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Chang Wang Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group | 2016 | Journal of Nutritional Oncology2016，1，1： | 7 |
| 9 | New Macroscopic Problematic Fossil from the Early Cambrian Yanjiahe Biota,Yichang,Hubei,China显示文摘Yanjiahella 情报。nov,从在 Yichang 的早寒武纪的 Yanjiahe 生物区系的特殊石块 taxon,湖北省,旁边被描绘:1 ) 一个全面身体计划梗和一个花萼创作了(也在某种类武装) ;2 ) 梗与仔细 spaced,横向的皱纹和一条中间的、纵的山脉;并且 3 ) 与三维的放射的有条纹或刻痕之状态保存的一个花萼,以及在一些标本的可能的 madreporite。能被分到这个类的三种,它是 Y。ancarpa sp。nov, Y。monocarpa sp。nov,和 Y。biscarpa sp。nov。Yanjiahella 以形态学和一些生物结构比得上某些棘皮动物类的动物 taxa,它可能从早早的寒武纪的 Yangtze 站台显示祖先的棘皮动物类的动物系的早进化和多样化。在 Yanjiahe 生物区系的通常认为的棘皮动物类的动物的发现关于 deuterostome 门棘皮类的起源和进化提供重要线索。 | GUO Junfeng LI Yong HAN Huiping OU Qiang ZHOU Jianren ZHENG Yajuan | 2012 | Acta Geologica Sinica(English Edition)2012，86，4： | 5 |
| 10 | Validity of the Chinese Version of the Patient-Generated Subjective Global Assessment (PG-SGA) in Gastric Cancer Patients显示文摘Purpose Malnutrition is severe among gastric cancer patients in China. While the Patient-Generated Subjective Global Assessment (PG-SGA) is a widely used nutritional assessment tool, the validation for Chinese patients with gastric cancer has not been performed yet. The aim of this research is to validate the Chinese version of the PGSGA in Chinese gastric cancer patients by conducting analyses of nutrition screening and assessment data. Methods Two thousand consecutive adult patients with gastric cancer were included in this observational, cross-sectional study in several tertiary hospitals in China. A survey was made among those patients, which included several questionnaires and some anthropometric parameters. We calculated the parameters to validate the use of PG-SGA categorizing the nutritional status of gastric cancer patients. Then we performed statistical analysis to evaluate the internal consistency, external consistency, and construct validity. Results This study verified the ability of the PG-SGA to differentiate gastric cancer patients into different nutritional groups. The confirmatory factor analysis verified the original four-factor structure of the PG-SGA. The internal and external consistency was measured by a concordance analysis which showed an intraclass correlation coefficients (ICC) of 0.987. The correlations of the Box 4 score with the Karnofsky performance status score demonstrated alternative form validity with good external consistency (Pearson, r = 0.643, P < 0.001). All three anthropometric dimensions of the PG-SGA were supported by principal component analysis. Spearman correlations (P < 0.001) were significant in the majority of tests. Conclusion The Chinese version of the PG-SGA is a valid tool to access the patients’ nutritional status for Chinese gastric patients. | Zhen Ming Fu Hong Xia Xu Chun Hua Song Wei Li Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Chang Wang Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers (INSCOC) Group | 2018 | Journal of Nutritional Oncology2018，3，4： | 5 |
| 11 | Novel fibrin-fibronectin matrix accelerates mice skin wound healing显示文摘Plasma fibrinogen(F1)and fibronectin(pFN)polymerize to form a fibrin clot that is both a hemostatic and provisional matrix for wound healing.About 90%of plasma F1 has a homodimeric pair ofγchains(γγF1),and 10%has a heterodimeric pair ofγand more acidicγ′chains(γγ′F1).We have synthesized a novel fibrin matrix exclusively from a 1:1(molar ratio)complex ofγγ′F1 and pFN in the presence of highly active thrombin and recombinant Factor XIII(rFXIIIa).In this matrix,the fibrin nanofibers were decorated with pFN nanoclusters(termedγγ′F1:pFN fibrin).In contrast,fibrin made from 1:1 mixture ofγγF1 and pFN formed a sporadic distribution of“pFN droplets”(termedγγF1+pFN fibrin).Theγγ′F1:pFN fibrin enhanced the adhesion of primary human umbilical vein endothelium cells(HUVECs)relative to theγγF1+FN fibrin.Three dimensional(3D)culturing showed that theγγ′F1:pFN complex fibrin matrix enhanced the proliferation of both HUVECs and primary human fibroblasts.HUVECs in the 3Dγγ′F1:pFN fibrin exhibited a starkly enhanced vascular morphogenesis while an apoptotic growth profile was observed in theγγF1+pFN fibrin.Relative toγγF1+pFN fibrin,mouse dermal wounds that were sealed byγγ′F1:pFN fibrin exhibited accelerated and enhanced healing.This study suggests that a 3D pFN presentation on a fibrin matrix promotes wound healing. | Carlos Poblete Jara Ou Wang Thais Paulino do Prado Ayman Ismail Frank Marco Fabian Han Li Licio A.Velloso Mark A.Carlson William Burgess Yuguo Lei William H.Velander Eliana P.Araújo | 2020 | Bioactive Materials2020，5，4： | 5 |
| 12 | Lipid Distribution in Marine Sediments from the Northern South China Sea and Association with Gas Hydrate显示文摘The distributions of lipids in surface and subsurface sediments from the northern South China Sea were determined. The n-alkanes were in bimodal distribution that is characterized by a centre at n-C16 –n-C20 with maximum at C18(or C19) and n-C27 –n-C31 as well as at C29(or C31). The short-chain alkanes suffered from significant losses due to their slow deposition in the water column, and their presence with a slight even carbon predominance in shallow seafloor sediments was ascribed mainly to the direct input from the benthos. The long-chain alkanes with odd predominance indicate transportion of terrigenous organic matter. Immature hopanoid biomarkers reflect the intense microbial activity for bacteria–derived organic matter and the gradual increase of maturity with burial depth. Abundant n-fatty acid methyl esters(n-FAMEs) that are in distributions coincident with fatty acids were detected in all samples. We proposed that the observed FAMEs originated from the methyl esterification of fatty acids; methanol production by methanotrophs and methanogenic archaea related to the anaerobic oxidation of methane, and sulfate reduction provided an O–methyl donor for methylation of fatty acids. The CH4 released from hydrate dissociation at oxygen isotope stage II of Cores ZD3 and ZS5, which had been confirmed by the occurrence of negative δ13C excursion and spherical pyrite aggregates, could have accelerated the above process and thus maximized the relative content of FAMEs at ZD3-2(400–420 cm depth) and ZS5-2(241–291 cm depth). | OU Wenjia LEI Huaiyan LU Wanjun ZHANG Jie SHI Chunxiao GONG Chujun HAN Chao | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 4 |
| 13 | Single Beacon Cruise Positioning Algorithm in Wireless Sensor Networks显示文摘 | ZHU Darong HAN Jianghong OU Jian MIN Jie | 2013 | Chinese Journal of Electronics2013，22，3： | 4 |
| 14 | Dampness in dwellings and its associations with asthma and allergies among children in Chongqing: A cross-sectional study显示文摘The city of Chongqing has high outdoor temperatures and humidity throughout the year and consequently a high risk of dampness and mold problems in dwellings.As part of the China,Children,Homes,Health(CCHH),associations between home characteristics and children’s asthma,allergies,and related symptoms were investigated in Chongqing,China.A cross-sectional questionnaire survey on home characteristics including dampness and symptoms of asthma and allergies in 5299 children was performed.Data for 4754 children(3–6 years)and their homes were analyzed.Results showed that 35.1%of homes were reported to have'damp bedding',14.3%'condensation on window panes(higher than 5 cm)',11.6%'mouldy odor',9.3%'water leakage',8.3%'damp stains'and 5.3%'visible mould'.Wheezing and rhinitis ever were reported for 27.0%and 51.1%children respectively,and rhinitis,wheezing,cough at night and eczema in the last 12 months were reported for 38.1%,20.5%,18.9%and 13.2%respectively.Doctor-diagnosed asthma was reported for 8.3%of children,and doctor-diagnosed rhinitis for 6.2%.Dampness in homes was generally strongly associated with asthma and allergies among Chongqing children.The strongest association was found between'visible mould'and doctor-diagnosed rhinitis,and the adjusted Odds Ratio(ORA)was 2.27(95%CI:1.48,3.49).'Damp bedding'was significantly associated with all asthma and allergic symptoms,but doctor-diagnosed asthma and rhinitis.The behavior of'putting bedding to sunshine'could effectively reduce the prevalence of asthma and allergic symptoms,and the risk of bedding affected with damp was reduced significantly when bedding was put to sunshine frequently. | WANG Han LI BaiZhan YANG Qin YU Wei WANG Juan LIU YiLong OU YangJin SUNDELL Jan | 2013 | Chinese Science Bulletin2013，58，34： | 4 |
| 15 | Efficiency of Slit Dam Prevention against Non-Viscous Debris Flow显示文摘This paper describes an experimental work in order to assess the efficiency of slit dam on non-viscous debris flow. Some results have been acquired as follows: ① there are three kinds of blocking type: Total-blocking, opening and part-blocking. The blocking conditions of slit dam are closely link to b/d_ max (the ratio of slit width to maximum diameter of solid matter), as b/d_ max is less than 0.739, the slit dam is total- blocking; and b/d_ max is more than 1.478, the slit dam will be opening; whereas b/d_ max ranges from 0.739 to 1.478, the slit dam is part-blocking. ② Variation of the mean density passing through slit dam is the most obvious as b/d_ max ranges from 0.739 to 1.232. ③ According to experimental results, slit dams have been shown to be effective in reducing debris flow density while slit density ∑b/B (B is slit dam width) ranges from 0.2 to 0.5. | HAN Wenbing OU Guoqiang | 2006 | Wuhan University Journal of Natural Sciences2006，11，4： | 4 |
| 16 | Benefit of infusions with ibandronate treatment in children with osteogenesis imperfecta显示文摘背景成骨 imperfecta (OI ) 是稀罕骨头疾病,它的有效治疗是相对缺乏的。我们试着估计新 bisphosphonate 的效果,有在这开标签的、未来的、控制研究的 OI.Methods 的孩子上的 ibandronate,有 OI 的 30 个孩子被注册。他们在每三个月或口头的 calcitriol 内收到了 ibandronate (2 mg ) 的任何一个注入为 24 个月的 0.25 g 日报。所有病人每天一起加 200 U 维生素 D 拿了 500 mg 钙。端点是年度新破裂率的变化(由病历和脊骨的 X 光线电影观察了),骨头矿物质密度( BMD ,由双精力X光检查 absortiometry 测量了),类型骨胶原的 carboxy-telopeptide 交叉结合的浆液集中( CTX ,骨头再吞标记)并且碱的磷酸酶(高山,骨头形成标记)在在 ibandronate 的周期的注入以后的 follow-up.Results 期间,年度新破裂率显著地从 1.9~0.13 次被减少,显然更低的 t 在 ibandronate 组的 BMD 的增加比 calcitriol 组(P 0.001 ) 的大。高山和 CTX 的集中显然在 ibandronate 组被减少,并且 CTX 的减小比高山(P 0.001 ) 的更重要。到 ibandronate 的孩子们的忍耐相当好。温和发烧和肌肉疼痛在 ibandronate 的第一注入以后在 1-3 天以内在 9 种情况中被发现,没有到有 OI 的孩子的 ibandronate 的周期的注入的好处是的特殊 management.Conclusions ,它能在 1-2 以后减轻天重要因为 ibandronate 能显著地减少年度骨头骨折,评价,增加腰部、新潮的 BMD ,通过骨头再吞的抑制保存病人的脊椎的 morphometry 。 | LI Mei XIA Wei-bo XING Xiao-ping YU Wei HU Ying-ying JIANG Yan WANG Ou LIU Hai-juan HAN Lan-wen MENG Xun-wu XU Ling | 2011 | Chinese Medical Journal2011，，19： | 4 |
| 17 | Reductive transformation and detoxification mechanism of 2,4-dinitrochlorobenzene in combined zero valent iron and anaerobic-aerobic process显示文摘A combined zero valent iron (ZVI) and anaerobic-aerobic process was adopted for the treatment of 2,4-dinitrochlorobenzene (DNCB)-containing wastewater. The transformation pathway, reduction of acute toxicity and enhancement of biodegradability were investigated. After pretreatment by ZVI, DNCB in wastewater could be completely converted into 2,4-diaminochlorobenzene (DACB). The ratio of BOD5/COD increased from 0.005±0.001 to 0.168±0.007, while EC 50, 48 hr (V/V) increased from 0.65% to 5.20%, indicating the enhancement of biodegradability and reduction of acute toxicity with the pretreatment by ZVI. DACB was further dechlorinated to m-phenylenediamine during the anaerobic process using methanol as electron donor, with EC50, 48 hr increasing from 5.20% to 48.2%. After the subsequent anaerobic-aerobic process, m-phenylenediamine was degraded completely, with effluent COD of 67.5±10.8 mg/L. This effluent of the subsequent anaerobic-aerobic process was not toxic to zebrafish. The combined ZVI and anaerobic-aerobic process offers bright prospects for the treatment of chlorinated nitroaromatic compound-containing wastewater. | Jinyou Shen Zongyuan Zhou Changjin OU Xiuyun Sun Jiansheng Li Weiqing Han Lin Zhou Lianjun Wang | 2012 | Journal of Environmental Sciences2012，24，11： | 4 |
| 18 | Extension Protocol for the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC)Study:2021 update显示文摘Background Malnutrition is common in patients with cancer,and this adversely affects the survival and quality of life of patients.Chinese Society for Nutritional Oncology issued a multi-center,large-scale,long-term follow-up prospective study,the Investigation on Nutrition Status and Clinical Outcome of Patients with Common Cancers in China(INSCOC study)since 2013.This is an extension to the previous 2013-2020 study protocol.This study still sought to:①address the prognostic impact of nutritional factors and quality of life on cancer patient survival;②describe the overall and cancer-specific incidence and/or distribution of malnutrition and different measurements of patient quality of life.Methods and study design This is an observational,multi-centered,hospital-based prospective cohort study.Data collection will be performed at baseline(within 48 hours after patient admission),during the hospital stay and 30 days after hospital admission.Follow-up will be conducted for 1-20 years after enrollment.The primary outcome will be the all-cause mortality/overall survival,and secondary outcomes will be the length of hospital stay and costs of hospitalization.Study factors will include demographic characteristics,tumor characteristics,information about chronic diseases,hematological measurements(e.g.,red blood cell count,total lymphocyte counts,hemoglobin,albumin,prealbumin,creatinine,C-reactive protein,IL-6),anthropometric measurements(e.g.,height,weight,arm circumference,arm muscle circumference,triceps skinfold thickness,and waist circumference),body composition parameters,PG-SGA scores,quality of life(as indicated by the QLQ-C30 questionnaire),muscle mass(as indicated by the calf circumference),muscle strength(as indicated by the handgrip strength),muscle function(as indicated by the six-meter walking speed test)and physical status assessments(as indicated by the Karnofsky Performance Status scores).This clinical study protocol was approved by local Ethics Committees of all the participating hospitals.Written informed consent is required for each subject included.Discussion This multi-center,large-scale,long-term follow up prospective study will help improve the diagnosis of malnutrition in cancer patients and identify the risk factors associated with adverse clinical outcomes.The anticipated results of this study will highlight the need for a truly scientific appraisal of nutrition therapy in Chinese oncology populations,and finally help treat the potentially reversible elements of malnutrition in cancer patients to improve their clinical outcomes in the future. | Hong Xia Xu Chun Hua Song Liang Yu Yin Chang Wang Zhen Ming Fu Zeng Qing Guo Yuan Lin Ying Ying Shi Wen Hu Yi Ba Su Yi Li Zeng Ning Li Kun Hua Wang Jing Wu Ying He Jia Jun Yang Cong Hua Xie Fu Xiang Zhou Xin Xia Song Gong Yan Chen Wen Jun Ma Su Xia Luo Zi Hua Chen Zhi Kang Chen Ming Hua Cong Hu Ma Chun Ling Zhou Wei Wang Qi Luo Yong Mei Shi Yu Mei Qi Hai Ping Jiang Wen Xian Guan Jun Qiang Chen Xiang Hua Wu Jia Xin Chen Yu Fang Lan Zhou Yong Dong Feng Rong Shao Tan Tao Li Jun Wen Ou Qing Chuan Zhao Jian Xiong Wu Min Weng Qing Hua Yao Ya Yin Yu Quan Jun Lyu Hong Qiu Ming Liu Wei Li Han Ping Shi The Investigation on Nutrition Status and Clinical Outcome of Common Cancers(INSCOC)Group | 2022 | Journal of Nutritional Oncology2022，7，2： | 3 |
| 19 | Morphological and electrophysiological properties of single myocardial cells from Koch triangle of rabbit heart显示文摘Background The morphological and electrophysiological characteristics of cardiac cells in Koch triangle are still disputed.We studied the appearance and electrical properties of these diverse myocytes to elucidate their complex electrophysiological phenomena.Methods Experiments were conducted using cooled charge coupling device(CCD) system and whole cell,patch clamp technique to determine the morphology,action potential and sodium current density of single viable myocytes enzymatically isolated from the Koch triangle of rabbit hearts.Results Morphologically,cardiac cells in shape of spider,tiny spindle,slender spindle,rod and strip were observed in percentage of 3.0±0.3,35.0±5.0,15.0±2.0,40.0±5.0 and 6.0±0.7 respectively.The cellular dimensions and capacitance gradually increased in the above order(all P<0.05).Electrophysiologically,action potential configurations recorded from them were similar respectively to nodal(N),atrial nodal(AN),nodal Hisian(NH),atrial(A) and Hisian like potentials obtained from the intact atrioventricular nodal preparations.Diastolic depolarization appeared in all myocytes except for rod cells.Sodium current density increased in the order of tiny spindle,strip,rod,slender spindle cell(all P<0.05),but could not be detected in spider-shaped cells.Linear regression analysis revealed that membrane capacitance was correlated negatively to the rate of diastolic depolarization r=-0.70,P<0.001,but positively to maximum depolarization potential,amplitude of action potential,upstroke velocity and maximum peak value of sodium current density r=0.84,0.80,0.87 and 0.75,respectively;all P<0.001.Conclusions The results demonstrated that spider-shaped,spindle,rod and strip cells in Koch triangle might correspond to pacemaking,transitional,atrial and Purkinje like cells,respectively.Furthermore,tiny spindle and slender spindle cells were referred to transitional cell α(TCα) and β(TCβ) accordingly considering their distinctive electrical properties.Different myocytes with diverse electrical properties constituted the infrastructure of sophisticated electrophysiological phenomena in Koch triangle.In view of the prominent percentage and electrical properties,tiny spindle and slender spindle cells were presumed to play important roles. | REN Fu-xian NIU Xiao-lin OU Yan HAN Zhen-hua LING Feng-dong ZHOU Shi-sheng LI Ya-jie | 2006 | Chinese Medical Journal2006，，24： | 3 |
| 20 | High performance of a unique mesoporous polystyrene-based adsorbent for blood purification显示文摘A multi-functional polystyrene based adsorbent(NKU-9)with a unique mesoporous and a high surface area was prepared by suspension polymerization for removal of therapeutic toxins in blood purification.The adsorbent produced had an almost equal amount of mesopore distribution in the range from 2 to 50 nm.The adsorption of serum toxins with different molecular weights were examined by in vitro adsorption assays and compared with some clinical currently used adsorbents such as HA-330,Cytosorb and BL-300 which are produced by China,America and Japan,respectively.Test results indicated that the adsorption rate for pentobarbital by NKU-9 was 81.24%which is nearly as high as HA-330(81.44%).The latter adsorbent is currently used for acute detoxification treatment in China.To reach adsorption equilibrium,NKU-9 was faster than HA-330,which implies short treatment time.For the removal of middle molecular toxins such as b2-microglobulin(98.88%),NKU-9 performed better adsorptive selectivity than Cytosorb(92.80%).In addition,NKU-9 showed high performance for the removal of albumin-bound toxins(e.g.,bilirubin),and its adsorption rate for total bilirubin(80.79%)in plasma was 8.4%higher than that of anion exchange resin BL-300 which is currently used to eliminate bilirubin in clinic.Therefore,our results indicate that the newly developed adsorbent with a wide distribution and almost equal amount of mesopores is a multifunctional adsorbent for high efficient removal of serum toxins with different molecular weights which might be an excellent blood purification adsorbent especially to treat diseases that conventional medical methods are low or not efficient. | Jian Chen Wenyan Han Jie Chen Wenhui Zong Weichao Wang Yue Wang Guanghui Cheng Chunran Li Lailiang Ou Yaoting Yu | 2017 | Regenerative Biomaterials2017，4，1： | 3 |
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