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3篇 您的检索式:作者名="Taipin Guo"
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1Cerebral fractional amplitude of low-frequency fluctuations may predict headache intensity improvement following acupuncture treatment in migraine patients显示文摘OBJECTIVE:To explore how baseline resting-state cerebral function predicts clinical outcomes of acupuncture treatment for migraine.METHODS:One hundred migraine patients and 46 healthy subjects were recruited.Patients were randomized into the acupuncture,sham acupuncture,and waiting list groups.Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments.Fractional amplitude of low-frequency fluctuations(f ALFF)calculations were applied to explore the associations between baseline f ALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group.RESULTS:Compared with healthy subjects,migraine patients had lower f ALFF in the left rostral ventromedial medulla,right thalamus,left amygdala,and right angular gyrus.Regression analyses revealed that baseline f ALFF values in the left middle frontal gyrus,left superior temporal gyrus,and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group,while baseline f ALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group.CONCLUSION:The baseline f ALFF values of brain regions associated with cognitive pain modulation,but not migraine severity,may predict future headache intensity improvement levels in migraine patients receiving acupuncture treatment.Li Zhengjie Zhou Jun Cheng Shirui Lan Lei Sun Ruirui Liu Mailan Yang Jie Gao Yujie Guo Taipin Gong Qiyong Zeng Fang Liang Fanrong 2020Journal of Traditional Chinese Medicine2020,40,6:5
2A central analgesic mechanism of acupuncture for migraine An ongoing functional MRI study显示文摘Shaoyang acupoints are the most frequently used in migraine treatment.However,the central analgesic mechanism remains poorly understood.Studies have demonstrated that single stimulus of the verum acupuncture in healthy subjects can induce significant connectivity or activity changes in painrelated central networks compared with sham acupuncture.However,these findings are not indicative of the central analgesic mechanism of acupuncture at Shaoyang acupoints.Thus,we recruited 100migraine sufferers and randomly assigned them into five groups:Shaoyang uncommon acupoint,Shaoyang common acupoint,Yangming uncommon acupoint,non-acupoint control,and blank control groups.Subjects were subjected to evaluation of curative effects and functional MRI prior to and after10 and 20 acupuncture treatments.All subjects were diagnosed by physicians and enrolled following clinical physical examination.Subjects were observed during 1–4 weeks after inclusion.At the fifth week,the first clinical evaluation and resting functional MRI were conducted.The Shaoyang uncommon acupoint,Shaoyang common acupoint,Yangming uncommon acupoint,and non-acupoint control grousp then were treated with acupuncture,five times per week,20 times in total over 4 weeks.The second and third clinical evaluations and resting functional MRI screenings were conducted following10 and 20 acupuncture treatments.The blank control group was observed during the 5 to 8 week period,followed by clinical evaluation and resting functional MRI.The aim of this study was to examine changes in brain functional activity and central networks in subjects with migraine undergoing acupuncture at Shaoyang uncommon acupoints.This study provides a further explanation of the central analgesic mechanism by which acupuncture at Shaoyang acupoints treats migraine.Lei Lan Yujie Gao Fang Zeng Wei Qin Mingkai Dong Mailan Liu Taipin Guo Fanrong Liang 2013Neural Regeneration Research2013,8,28:3
3Effect of catgut embedding at acupoints versus non-acupoints in abdominal obesity:a randomized clinical trial显示文摘OBJECTIVE:To explore the difference of catgut embedding effect between acupoints and non-acupoints in patients with abdominal obesity(AO).METHODS:In this multicenter,double-blind,randomized controlled trial,all subjects were randomly assigned into the acupoint catgut embedding(ACE)group and control group(catgut embedding at non-acupoints).With a 12-week actual intervention period and a 4-week period of follow-up.Waist circumference(WC),body weight,body mass index(BMI),hip circumference(HC)and appetite were applied and assessed at baseline and after 6,12 and 16 weeks.RESULTS:After the total intervention phase(12 weeks),the WC,body weight,BMI,HC and visual analogue scale scores of appetite,decreased significantly in the two groups as compared to the baseline(P<0.001).Meanwhile,after the 4-week follow-up,the indicators still decreased significantly in the ACE group(P<0.001).At 12 and 16 weeks,catgut embedding at acupoints showed significantly advantages to non-acupoints in WC and appetite(P<0.05).No serious adverse events were observed in ACE group and control group.CONCLUSIONS:Catgut embedding at acupoints and non-acupoints are all effective and safe for AO.ACE can effectively treat AO as expected and deliver lasting results.ZHANG Xinghe LI Qifu YI Rong XING Chonghui JIN Yuhao MENG Jiangqiong FENG Jialei ZHAO Siwen LIANG Fanrong GUO Taipin 2023Journal of Traditional Chinese Medicine2023,43,4:0
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