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| 1 | Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan显示文摘AIM: To examine the long term survival of geriatric patients treated with percutaneous endoscopic gastrostomy (PEG) in Japan. METHODS: We retrospectively included 46 Japanese community and tertiary hospitals to investigate 931 consecutive geriatric patients (≥ 65 years old) with swallowing difficulty and newly performed PEG between Jan 1st 2005 and Dec 31st 2008. We set death as an outcome and explored the associations among patient’s characteristics at PEG using log-rank tests and Cox proportional hazard models. RESULTS: Nine hundred and thirty one patients were followed up for a median of 468 d. A total of 502 deaths were observed (mortality 53%). However, 99%, 95%, 88%, 75% and 66% of 931 patients survived more than 7, 30, 60 d, a half year and one year, respectively. In addition, 50% and 25% of the patients survived 753 and 1647 d, respectively. Eight deaths were considered as PEG-related, and were associated with lower serum albumin levels (P = 0.002). On the other hand, among 28 surviving patients (6.5%), PEG was removed. In a multivariate hazard model, older age [hazard ratio (HR), 1.02; 95% confidence interval (CI), 1.00-1.03; P = 0.009], higher C-reactive protein (HR, 1.04; 95% CI: 1.01-1.07; P = 0.005), and higher blood urea nitrogen (HR, 1.01; 95% CI: 1.00-1.02; P = 0.003) were significant poor prognostic factors, whereas higher albumin (HR, 0.67; 95% CI: 0.52-0.85; P = 0.001), female gender (HR, 0.60; 95% CI: 0.48-0.75; P < 0.001) and no previous history of ischemic heart disease (HR, 0.69; 95% CI: 0.54-0.88, P = 0.003) were markedly better prognostic factors. CONCLUSION: These results suggest that more than half of geriatric patients with PEG may survive longer than 2 years. The analysis elucidated prognostic factors. | Yutaka Suzuki Seryna Tamez Akihiko Murakami Akihiko Taira Akihiro Mizuhara Akira Horiuchi Chie Mihara Eiji Ako Hirohito Muramatsu Hitoshi Okano Hitoshi Suenaga Kazuaki Jomoto Junya Kobayashi Katsunari Takifuji Kazuhiro Akiyama Koh Tahara Koji Onishi Makoto Shimazaki Masami Matsumoto Masashi Ijima Masato Murakami Masato Nakahori Michiaki Kudo Michio Maruyama Mikako Takahashi Naohiro Washizawa Shigeru Onozawa Satoshi Goshi Satoyoshi Yamashita Shigeki Ono Shin Imazato Shinji Nishiwaki Shuichirou Kitahara Takao Endo Takao Iiri Takeshi Nagahama Takuto Hikichi Tatsuya Mikami Tetsuo Yamamoto Tetsushi Ogawa Tomoko Ogawa Tomoyuki Ohta Toshifumi Matsumoto Toshiroh Kura Tsutomu Kikuchi Tsuyoshi Iwase Tsuyotoshi Tsuji Yukio Nishiguchi Mitsuyoshi Urashima | 2010 | World Journal of Gastroenterology2010，16，40： | 4 |
| 2 | Biologically active all- kylated coumarins from Kayea assamica 显示文摘 | Lee KH Chai HB Tamez PA | 2003 | Phytochem2003，64，2： | 1 |
| 3 | Design concepts and principle of operation of the HeartWare ventricular assist system 显示文摘 | Larose JA Tamez D Asgenuga M | 2010 | ASAIO2010，56，： | 1 |
| 4 | HeartWare miniature axial-flow ventrieular assist device-design and initial feasibility test显示文摘 | Slaughter MS Sobieski MA Tamez D | 2009 | Tex Heart Inst J2009，36，1： | 1 |
| 5 | Design concepts and principle of operation of the HearrtWare ventricular assist system显示文摘 | Larose JA Tamez D Ashenuga M | 2010 | ASAIO J2010，56，4： | 1 |
| 6 | Adsorptive removal of methylene blue by tea waste显示文摘 | Md. Tamez Uddin Md. Akhtarul Islam Shaheen Mahmud Md. Rukanuzzaman | 2008 | Journal of Hazardous Materials2008，，1： | 1 |
| 7 | Active vitamin D treatment for reduction of residual proteinuria:a systematic review显示文摘 | de Borst MH Hajhosseiny R Tamez H | 2013 | J Am Soc Nephrol2013，24，11： | 1 |
| 8 | Klotho variants and chronic hemodialysis mortality显示文摘 | Friedman DJ Afkarian M Tamez H | 2009 | J Bone Miner Res2009，24，11： | 1 |
| 9 | N-terminal pro-B- type natriuretic peptide 显示文摘 | Gutierrez OM Tamez H Bhan I | 2008 | Clin Chem2008，54，8： | 1 |
| 10 | Adsotive removal of methylene blue by tea waste显示文摘 | Md Tamez Uddin Md Akhtarul Islam Shaheen Mahmud | 2009 | Joumal of Hazardous Materials2009，164，1： | 1 |
| 11 | Active vitamin D treatment for reduction of residual proteinuria: a systematic review显示文摘 | Borst MH Hajhosseiny R Tamez H | 2013 | J Am Soc Nephrol2013，24，11： | 1 |
| 12 | Natural anti-HIV agents - part I: (+)-demethoxyepiexcelsin and verticillatol from Litsea verticillata显示文摘 | Hoang V.D Tan G.T Zhang H.-J Tamez P.A Hung N.V Cuong N.M Soejarto D.D Fong H.H.S. Pezzuto J | | 0，，3： | 1 |
| 13 | Biologically Active Allkylatedcoumarins from Kayeaassamica显示文摘 | Lee K H Chai H B Tamez P A Pezzuto J M Cordell G A Win K K TinWa M | 2003 | Phyto Chemistry2003，64，2： | 1 |
| 14 | Structural change and estimated persistence in the GARCH (1,1)-model显示文摘 | Walter Kramer Baudouin Tameze Azamo | | 0，，： | 1 |
| 15 | Biventricular support with the Jarvik 2000 axial flow pump:a feasibility study显示文摘 | Radovancevic B Gregoric ID Tamez D | | 0，，05： | 1 |
| 16 | Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease显示文摘 | Tamez H Zoccali C Packham D | 2012 | Am Heart J2012，164，6： | 1 |
| 17 | Vitamin D and chron-ic kidney disease Mineral bone disease (CKD-MBD) 显示文摘 | Nigwekar SU Tamez H Thadhani RI | 2014 | BoneKEy Reports2014，3，： | 1 |
| 18 | Active vitamin D treatment for reduction of residual proteinuria:a systematic review显示文摘 | De Borst MH Hajhosseiny R Tamez H | 2013 | J Am Soc Nephrol2013，24，： | 1 |
| 19 | Adsorptive removal of methylene blue by tea waste显示文摘 | Tamez Uddin M Akhtarul Islam M Mahmud S | 2009 | Journal of Hazardous Materials2009，164，1： | 1 |
| 20 | Klotho va- riants and chronic hemodialysis mortality显示文摘 | FRIEDMAN DJ AFKARIAN M TAMEZ H | 2009 | J Bone Miner Res2009，24，11： | 1 |
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