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| 1 | Development of distributed time-variant gain model for nonlinear hydrological systems显示文摘In this paper, a rainfall-runoff modeling system is developed based on a nonlinear Volterra functional series and a hydrological conceptual modeling approach. Two models, i.e. the time-variant gain model (TVGM) and the distributed time-variant gain model (DTVGM) that are built on the platform of Digital Elevation Model (DEM), Remote Sensing (RS) and Unit Hydro-logical Process were proposed. The developed DTVGM model was applied to two cases in the Heihe River Basin that is located in the arid and semiarid region of northwestern China and the Chaobai River basin located in the semihumid region of northern China. The results indicate that, in addition to the classic dynamic differential approach to describe nonlinear processes in hy-drological systems, it is possible to study such complex processes through the proposed sys-tematic approach to identify prominent hydrological relations. The DTVGM, coupling the advan-tages of both nonlinear and distributed hydrological models, can simulate variant hydrological processes under different environment conditions. Satisfactory results were obtained in fore-casting the time-space variations of hydrological processes and the relationships between land use/cover change and surface runoff variation. | XIA Jun1, 2, WANG Gangsheng1, TAN Ge1, YE Aizhong2 & G. H. Huang3 1. Key Laboratory of Water Cycle & Related Land Surface Processes, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China 2. State Key Laboratory of Water Resources & Hydropower Engineering Sciences, Wuhan University, Wuhan 430072, China 3. Faculty of Engineering, University of Regina, 3737 Wascana Parkway, Regina, Sask., S4S 0A2, Canada Correspondence should be addressed to Xia Jun | 2005 | Science China Earth Sciences2005，48，6： | 32 |
| 2 | Artificial coordinating field and its application to motion planning of robots in uncertain dynamic environments显示文摘Artificial coordinating fields (ACF) are proposed to deal with the motion planning problems of mobile robots in uncertain dynamic environments. An ACF around an obstacle can generate two orthogonal force vectors to a robot: one is called the coordinating force vector which is purposively designed in this paper, and the other is the repulsive force vector which is the same as that in a conventional artificial potential field. The ACF is designed according to the updated motion purpose and the relative states of the robot with respect to its local environment, and it also satisfies the robots dynamic constraints. The direction of the coordinating force can be determined on line according to an optimal evaluation function. The ACF can effectively remove the local minima, and reduce the oscillation of the planned trajectory between multiple obstacles. Only local knowledge of the environments is needed in the ACF-based motion planning. The properties of the ACF such as controllability, adaptability, safety and reachability are studied and discussed in detail in this paper. Theoretical analysis and simulations are given to illustrate our main results. | JING Xingjian1, 2, WANG Yuechao1 & TAN Dalong1 1. Robotics Laboratory, Shenyang Institute of Automation, Chinese Academy of Sciences, Shenyang 110016, China 2. Graduate School, Chinese Academy of Sciences, Beijing 100039, China Correspondence should be addressed to Jing Xingjian | 2004 | Science China(Technological Sciences)2004，47，5： | 11 |
| 3 | Protective Effect of Dimethyl-4,4'-Dimethoxy-5,6,5',6'-Dimethylene Dioxybiphenyl-2,2'-Dicarboxylate (DDB) against Carcinogen-Induced Rat Liver Nuclear DNA Damage显示文摘The protective effect fDDB against carcinogen-induced DNA damage was examined in the present investigation.Preincubation of rat liver nuclei with DDB(1mmol·L^-1)resulted in 60% inhibition of binding of ^3H-benzo(a)pyrene to nuclear DNA.unscheduled DNA synthesis(UDS)induced by aflatoxin B1(10^-7mol·L^-1) in freshly isolated rat hepatocytes was also inhibited by DDB(10^-6-10^-3mol·L^-1).Oral administation of DDB at 200mg·k^-1once daily for 3 d induced a significant increase of liver cytosol glutathione-S-transferase and microsomal UDPG-transferase activity in mice.These results indicate that DDB is able to directly or indirectly antagonize certain carcinogen-induced DNA damages. | QlNG WEIGUO1 AND LIU GENGTAODepartment of Pharmacology, Institute of Materia Medico, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050,ChinaBeijing Institute for Cancer Research, Da-Hong-Luo-Chang Street, West District, Beijing, 100034 China.To whom correspondence should be addressed. | 1992 | Biomedical and Environmental Sciences1992，5，3： | 4 |
| 4 | Theory,controls parameter and application of the packed-bed electroosmotic pump显示文摘Theory and controls parameters affecting the output pressure and flow rate of the packed-bed electroos-motic pump (p-EOP), including zeta potential z, electric in-tensity E, length of the column L, cross-section area of the column A, dielectric constant e and viscosity coefficient h of the liquid being pumped, are discussed concisely. And also, the fabrication and application of the p-EOP are introduced. | CHEN Lingxin, GUAN Yafeng, MA Jiping, SHU Xin & TAN Feng Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116012, China Correspondence should be addressed to Guan Yafeng (e-mail: kfguan@ mail.dlptt.ln.cn) | 2003 | Chinese Science Bulletin2003，48，23： | 3 |
| 5 | Ribozyme probe based on molecular beacon for real time monitoring of enzymatic cleavage process显示文摘Ribozyme probe based on molecular beacon (MBR) for monitoring enzymatic cleavage process in real time is designed and studied. The approach relies on ri-bozyme substrates modified at the two arms, with a fluores-cent moiety attached to the end of one arm and a non-fluorescent quenching moiety attached to the end of the other arm. MBR is employed to directly convert the cleavage information into fluorescence signal in real time. Compared with traditional approach, this method provides a no-radiolabeling, sensitive and effective way to research on the ribozyme activity, enzymatic dynamic process and ri-bozyme function during gene therapy. The activity of the ribozyme against hepatitis C virus RNA (HCV-RNA) is stud-ied based on this assay. | MENG Xiangxian, WANG Kemin, TAN Weihong, LI Jun, TANG Zhiwen, GUO Qiuping, HUANG Shasheng & LI Du State Key Laboratory of Chemo/Biosensing and Chemometrics, Institute of Biological Technology, College of Chemistry and Chemical Engi-neering, Hunan University, Changsha 410082, China Correspondence should be addressed to Wang Kemin (e-mail: kmwang @hnu.net.cn) | 2003 | Chinese Science Bulletin2003，48，23： | 3 |
| 6 | Protective Effects of Dimethyl-4,4'-Dimethoxy-5,6,5',6'-Dimethylene Dioxybiphenyl-2,2'-Dicarboxylate on Damages of Isolated Rat Hepatocytes Induced by Carbon Tetrachloride and D-galactosamine显示文摘The rotective effect of biphenyl dimethyl dicarboxylate(DDB)on chemically induced damages was studied in isolated suspended rat hepatocytes.The experimental results showed that DDB(200μg/10^6cells) efficiently protected the hepatocytes against carbon tetrachloride(CCl4 10mmol·L^-1)and D-galactosamine(1mmol·L^1)induce damages.Membranal lipid peroxidation(malondialdehyde,MDA formation(and glutamic pyruvic transaminase(GPT) release from the hepatocytes were markedly decreased.The damage of the cell surfaces of the hepatocytes were also reduced as seen under a scanning electrom microscope(SEM). Pretreatment with DDB(300mg·kg^-1)orally ameliorated the reduction of liver glycogen and blood glucose caused by ip injection of D-galactosamine(800mg·kg^-1)in mice.When normal rats were given DDB 300mg·kg^-1 once daily for 10d,the free ribosomal protein and RNA in the liver increased significantly.These results indicate that DDB is of beneficial effects on both damaged and normal hepatocytes. | FU TIEBO AND LIU GENGTAODepartment of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050,ChinaFox Chase Cancer Center. 7701 Burholme Avenue. Philadelphia, Pennsylvania 19111, USA.To whom correspondence should be addressed. | 1992 | Biomedical and Environmental Sciences1992，5，3： | 2 |
| 7 | Laparoscopic nephroureterctomy with bladder-cuff resection techniques and outcomes显示文摘 | Tan BJ Ost MC Lee BE | 2005 | Endourol2005，19，6： | 1 |
| 8 | A systematic review of the survival and complication rates of fixed partial dentures ( FPDS ) after an observation period of at least 5 years 显示文摘 | Pjetursson BE Tan k Lang NP | 2004 | Clin Oral Implants Res2004，15，6： | 1 |
| 9 | Upper- extremity pe- ripheral nerve blocks in the perioperative pain management of or- thopaedic patients: AAOS exhibit selection 显示文摘 | Srikumaran U Stein BE Tan EW | 2013 | J Bone Joint Surg Am2013，95，24： | 1 |
| 10 | Colossal magnetoresistance and spin-glass properties of La(1-x)TexMnO3(x=0.04,0.1)显示文摘For the first time, a novel material of La1-x- TexMnO3 (x = 0.04, 0.1), in which the La ions are replaced by the nonmetal element Te in the Chalcogen, has been synthesized. The material has a rhombohedral lattice with the space group of R3c, and Te ions have a tetravalence state. The curves of the resistivity vs. temperature indicate that this material has the property of a metal-semiconductor transition and the colossal magnetoresistance (CMR) effect. The maximum magnetoreistance ratio MR=[(0)()]/(0)H? is about 51% at 4 T for x = 0.1. Besides, a spin-glass behavior at low magnetic fields is observed in this compound. | TAN Guotai, DUAN Peng, DAI Shouyu, CHEN Zhenghao, LU Huibin & ZHOU Yueliang Laboratory of Optical Physics, Institute of Physics & Center for Condensed Matter Physics, Chinese Academy of Sciences, Beijing 100080, China Correspondence should be addressed to Chen Zhenghao (e-mail: zhchen @aphy.iphy.ac.cn) | 2003 | Chinese Science Bulletin2003，48，13： | 1 |
| 11 | Disparate effects on renal and oxidative parameters following RAGE deletion,AGE accumulation inhibition,or dietary AGE control in experimental diabetic nephropathy显示文摘 | Tan AL Sourris KC Harcourt BE | | 0，，： | 1 |
| 12 | A systematic review of thesurvival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years 显示文摘 | Pjetursson BE Tan K Lang NP | 2004 | Clin Oral Implants Res2004，15，： | 1 |
| 13 | A systematic review of the survival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years 显示文摘 | Tan K Pjetursson BE Lang NP | 2004 | Clin Oral Implants Res2004，15，： | 1 |
| 14 | Interferon-gamma-inducing factor elicits antitumor immunity in association with interferon-gamma production显示文摘 | Tan J Crucian BE | 1998 | J Immunother1998，21，1： | 1 |
| 15 | A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation显示文摘 | Pjetursson BE Tan WC Zwahlem M | 2008 | J Clin Periodontol2008，35，8： | 1 |
| 16 | Disparate effects on renal and oxidative parameters following RAGE deletion,AGE accumulation inhibition,or dietary AGE control in experimental diabetic nephropathy显示文摘 | Tan AL Sourris KC Harcourt BE | 2010 | Am J Physiol Renal Physiol2010，298，3： | 1 |
| 17 | A systematic re- view of the survival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years显示文摘 | Pjetursson BE Tan K Lang NP | 2004 | Clin Oral Implants Res2004，15，6： | 1 |
| 18 | A sys- tematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation显示文摘 | Pjetursson BE Tan WC Zwahlen M | 2008 | J Clin Periodontol2008，35，8： | 1 |
| 19 | A systematic review of the survival and complication rates of fixed partial dentures (FPDs) after an observation period of at least 5 years 显示文摘 | Pjetursson BE Tan K Lang NP | 2004 | Clin Oral Im- plants Res2004，15，6： | 1 |
| 20 | Major gastrointestinal manifestations in lupus patients in Asia: lupus enteritis, intestinal pseudo-obstruction, and protein-losing gastroenteropathy显示文摘 | Chng HH Tan BE Teh CL | 2010 | Lupus2010，19，12： | 1 |
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