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14篇 您的检索式：作者名="Tanja O"

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		题名	作者	年代	出处	被引量
	1	The relationship of the immunity and the disease of porcine circovirus type 2(PCV-2) 显示文摘	Ptric H Tanja O	2004	Pig International2004，34，3：	1
	2	Systemic therapy of advanced non-small cell lung cancer: Major-developments of the last 5-years显示文摘	Tanja Cufer Tanja Ovcaricek Mary E.R. O’Brien	2012	European Journal of Cancer2012，，：	1
	3	Silver-based crystalline nanoparti-cles,microbially fabricated显示文摘	TANJA K RALPH J EVA O	1999	Proc Natl Acad Sci1999，96，13：	1
	4	显示文摘	Gerhard H W Tanja M W Jurgen O B	1999	Electro- chem Commun1999，1，34：	1
	5	Propylene sulfite as film-forming electrolyte additive in lithium ion batteries 显示文摘	Gerhard H Wrodnigg Tanja M Wrodnigg Jurgen O Besenhard	1999	Electrochemistry Communications1999，1，34：	1
	6	A DNA vaccine based on a shuffled E7 oncogene of the human papillomavirus type 16 (HPV 16 ) induces E7-specific cytotoxic T ceils but lacks transforming activity 显示文摘	WOLFRAM O TANJA P SANDRA C	2001	Vaccine2001，19，30：	1
	7	PropyIene sulfite as film-forming electrolyte additive in lithium-ion batteries 显示文摘	Gehard H W Tanja M W Jurgen O B	1999	Electrochem Commun1999，1，34：	1
	8	Epidemiology and transmission of porcine circovirus type 2 (PCV2) 显示文摘	Nicolas R Tanja O	2012	Virus Res2012，164，：	1
	9	Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma显示文摘	Vasiliki Michopoulos Alex O Rothbaum Tanja Jovanovic	2015	American Journal of Psychiatry2015，172，4：	1
	10	The Mhc class II ofthe Black grouse (Tetrao tetrix)consists of low numbers of B andY genes with variable diversity and expression 显示文摘	Tanja S Westerdahl H H o glund J	2007	Immunogenetics2007，59，9：	1
	11	Structure and self-association of the Rous sarcoma virus capsid protein显示文摘	Richard L Kingston Tanja F O Elan Zohar Eisenmesser	2000	Structure2000，，8：	1
	12	Propylene sulfite as film-forming electrolyte additivein lithium ion batteries显示文摘	GERHARD H W TANJA M W JURGEN O B	1999	Electrochem Commun1999，，1：	1
	13	Model-based local pathplanning for UAVs显示文摘	Tanja H Robert B Frank O	2015	Journal of Intelligent and RoboticSystems: Theory and Applications2015，78，1：	1
	14	Upregulation of 25-hydroxyvitamin D_3-1α-hydroxylase by butyrate in Caco-2 cells显示文摘AIM: To investigate the possible involvement of 25-hydroxyvitamin D3-1α-hydroxylase [1α-25(OH)2D3] in butyrate-induced differentiation in human intestinal cell line Caco-2 cells.METHODS: Caco-2 cells were incubated either with 3 mmol/L butyrate and 1 μmol/L 25(OH)2D3 or with 1μmol/L 1α-25(OH)2D3 for various time intervals ranging from 0 to 72 h. Additionally, cells were co-incubated with butyrate and either 25(OH)2D3 or 1α-25(OH)2D3.1α-25(OH)2D3 mRNA was determined semi-quantitatively using the fluorescent dye PicoGreen. Immunoblotting was used for the detection of 1α-25(OH)2D3 protein.Finally, enzymatic activity was measured by ELISA.RESULTS: Both butyrate and 1α-25(OH)2D3 stimulated differentiation of Caco-2 cells after a 48 h incubation period, while 25(OH)2D3 had no impact on cell differentiation. Synergistic effects on differentiation were observed when cells were co-incubated with butyrate and vitamin D metabolite. Butyrate transiently upregulated 1α-25(OH)2D3 mRNA followed by a timely delayed protein upregulation. Coincidently, enzymatic activity was enhanced significantly. The induction of the enzyme allowed for comparable differentiating effects of both vitamin D metabolites.CONCLUSION: Our experimental data pr ovide a further mechanism for the involvement of the vitamin D signaling pathway in colonic epithelial cell differentiation by butyrate. The enhancement of 1α-25(OH)2D3 followed by antiproliferative effects of the vitamin D prohormone in the Caco-2 cell line suggest that 25(OH)2D3 in combination with butyrate may offer a new therapeutic approach for the treatment of colon cancer.	Oliver Schr(o\|¨)der Sinan Turak Carolin Daniel Tanja Gaschott Jürgen Stein	2005	World Journal of Gastroenterology2005，11，45：	0

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